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The map label for this gene is mdtA [H]

Identifier: 85375524

GI number: 85375524

Start: 2715213

End: 2716427

Strand: Direct

Name: mdtA [H]

Synonym: ELI_13485

Alternate gene names: 85375524

Gene position: 2715213-2716427 (Clockwise)

Preceding gene: 85375523

Following gene: 85375525

Centisome position: 88.95

GC content: 69.05

Gene sequence:

>1215_bases
ATGAACTACCAGCCGAATGAAATTCGAAGCGATACGCCGGTCGAGGTGCGGGGCGAGTCGCTCTCCACCACCGGTTATGG
CGAGCAGCGCGGGTTGCCGTGGCGTCTGATCGTGCTCGGCATCCTGATCGTCGGCGCGCTGGTCGCGGCATGGTATTTCT
TCGGCCAGGGTTCCGGAACCGCCGTCCCCGCGGCGGACCGGGACGACCAGGCGCCGCGCATCACGGTGGTGACGCCGGGC
CGCACCACCATCGAAGGCACGATCAGCGCGACCGGTTCGCTCGCTGCACGGCGCGAAATGCCGGTCGGTGTCGTCGGCGA
AGGCGGGCGGGTGGTTTCGGTGCCGGTGGAACAGGGCCAGTGGGTCCGCGCCGGCCAGGTCCTCGCTTCGATCGACCAGT
CCGTGCAGAGCCAGCAGGCCCGCGCGCAGGCGGCGCAGATCGAAGTCGCCCGCGCCGATGCCGAACTTGCGCAGTCGAAC
CTCGACCGCGCATTGCAACTGGTCGAGCGCGGTTTCATCTCCAAGGCCGACGTCGATCGCCTCACGGCTACGCGCGATGC
GGCGCGGGCCCGTGTCCAGGTGGCGCAGGCCCAGCTCAACGAATTGCGCGCGCGCAACGCCCGGCTCAATATCGTCGCCC
CCGCTGCCGGCCTGCTGCTCGAACGCAATGTCGAGCCGGGTGCAACCGTCAGTGCGGGCTCGCCACCGCTGTTCCGCATC
GCCCGTGGCGGCGAGATGGAATTGCGCGCGCAAGTCGGCGAAAGCGACCTCGCCCGGCTTTCGGTCGGCGTGCAGGCCTC
GGTCGTGCCCTCGGGCACCGACAAGAGTTTCGTCGGCCAGATCTGGCAGCTCGCGCCCACCATCGATGCGCAGAATCGCC
AGGGTACGGCGCGCATCGCGCTGCCTTACGCACCCGAGCTTCGCCCCGGCGGCTTCGCCACGGCGACGATCCAGAGCGGC
ACGGTGGTCGCACCGATGCTGCCCGAATCGGCAATTCTTTCCGATGACGACGGCGCCTTCGTCTATATCGTCGATGCCGA
GAACAAGGCGCGCCGCCGCGGCGTCACGACCGGGATCGTGACGCGTGACGGCATCGCCGTCATCGATGGCCTCGACGGAA
GCGAGAAGGTCGTCCTGCGCGCCGGCGGATTCCTGACCGAAGGCGAGACCATCGCACCGCAGCAGGCGGACGCAGAGACC
CGGACCGGGGGCTGA

Upstream 100 bases:

>100_bases
GCTCGCGAATCGCCGCGCCTAGGCAGTTTCGGAGCACCTTGCGCTAGGTGACTTATATAGGTAATACAGCGGCTCCCTTC
GGGCCGGCGACAGGAACCGT

Downstream 100 bases:

>100_bases
TCGGCATGAACTTCCGCAACATCTCCGCCTGGTCGATCCGCAACCCGACGATACCGCTGGTCTTCTTCACCGCGATCCTG
TTCGCCGGGATCATGGCCTT

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNYQPNEIRSDTPVEVRGESLSTTGYGEQRGLPWRLIVLGILIVGALVAAWYFFGQGSGTAVPAADRDDQAPRITVVTPG
RTTIEGTISATGSLAARREMPVGVVGEGGRVVSVPVEQGQWVRAGQVLASIDQSVQSQQARAQAAQIEVARADAELAQSN
LDRALQLVERGFISKADVDRLTATRDAARARVQVAQAQLNELRARNARLNIVAPAAGLLLERNVEPGATVSAGSPPLFRI
ARGGEMELRAQVGESDLARLSVGVQASVVPSGTDKSFVGQIWQLAPTIDAQNRQGTARIALPYAPELRPGGFATATIQSG
TVVAPMLPESAILSDDDGAFVYIVDAENKARRRGVTTGIVTRDGIAVIDGLDGSEKVVLRAGGFLTEGETIAPQQADAET
RTGG

Sequences:

>Translated_404_residues
MNYQPNEIRSDTPVEVRGESLSTTGYGEQRGLPWRLIVLGILIVGALVAAWYFFGQGSGTAVPAADRDDQAPRITVVTPG
RTTIEGTISATGSLAARREMPVGVVGEGGRVVSVPVEQGQWVRAGQVLASIDQSVQSQQARAQAAQIEVARADAELAQSN
LDRALQLVERGFISKADVDRLTATRDAARARVQVAQAQLNELRARNARLNIVAPAAGLLLERNVEPGATVSAGSPPLFRI
ARGGEMELRAQVGESDLARLSVGVQASVVPSGTDKSFVGQIWQLAPTIDAQNRQGTARIALPYAPELRPGGFATATIQSG
TVVAPMLPESAILSDDDGAFVYIVDAENKARRRGVTTGIVTRDGIAVIDGLDGSEKVVLRAGGFLTEGETIAPQQADAET
RTGG
>Mature_404_residues
MNYQPNEIRSDTPVEVRGESLSTTGYGEQRGLPWRLIVLGILIVGALVAAWYFFGQGSGTAVPAADRDDQAPRITVVTPG
RTTIEGTISATGSLAARREMPVGVVGEGGRVVSVPVEQGQWVRAGQVLASIDQSVQSQQARAQAAQIEVARADAELAQSN
LDRALQLVERGFISKADVDRLTATRDAARARVQVAQAQLNELRARNARLNIVAPAAGLLLERNVEPGATVSAGSPPLFRI
ARGGEMELRAQVGESDLARLSVGVQASVVPSGTDKSFVGQIWQLAPTIDAQNRQGTARIALPYAPELRPGGFATATIQSG
TVVAPMLPESAILSDDDGAFVYIVDAENKARRRGVTTGIVTRDGIAVIDGLDGSEKVVLRAGGFLTEGETIAPQQADAET
RTGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=337, Percent_Identity=27.893175074184, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081796, Length=378, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42488; Mature: 42488

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQPNEIRSDTPVEVRGESLSTTGYGEQRGLPWRLIVLGILIVGALVAAWYFFGQGSGT
CCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
AVPAADRDDQAPRITVVTPGRTTIEGTISATGSLAARREMPVGVVGEGGRVVSVPVEQGQ
CCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHCCCEEEECCCCEEEEEECCCCC
WVRAGQVLASIDQSVQSQQARAQAAQIEVARADAELAQSNLDRALQLVERGFISKADVDR
EEHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LTATRDAARARVQVAQAQLNELRARNARLNIVAPAAGLLLERNVEPGATVSAGSPPLFRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCCEECCCCCCEEEE
ARGGEMELRAQVGESDLARLSVGVQASVVPSGTDKSFVGQIWQLAPTIDAQNRQGTARIA
ECCCCEEEEEECCCCHHHHEEECEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LPYAPELRPGGFATATIQSGTVVAPMLPESAILSDDDGAFVYIVDAENKARRRGVTTGIV
ECCCCCCCCCCEEEEEECCCEEEECCCCCCCEEECCCCCEEEEEECCCCHHHCCCEEEEE
TRDGIAVIDGLDGSEKVVLRAGGFLTEGETIAPQQADAETRTGG
ECCCEEEEECCCCCCEEEEEECCEEECCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MNYQPNEIRSDTPVEVRGESLSTTGYGEQRGLPWRLIVLGILIVGALVAAWYFFGQGSGT
CCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
AVPAADRDDQAPRITVVTPGRTTIEGTISATGSLAARREMPVGVVGEGGRVVSVPVEQGQ
CCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCHHHHHCCCEEEECCCCEEEEEECCCCC
WVRAGQVLASIDQSVQSQQARAQAAQIEVARADAELAQSNLDRALQLVERGFISKADVDR
EEHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LTATRDAARARVQVAQAQLNELRARNARLNIVAPAAGLLLERNVEPGATVSAGSPPLFRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCCEECCCCCCEEEE
ARGGEMELRAQVGESDLARLSVGVQASVVPSGTDKSFVGQIWQLAPTIDAQNRQGTARIA
ECCCCEEEEEECCCCHHHHEEECEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LPYAPELRPGGFATATIQSGTVVAPMLPESAILSDDDGAFVYIVDAENKARRRGVTTGIV
ECCCCCCCCCCEEEEEECCCEEEECCCCCCCEEECCCCCEEEEEECCCCHHHCCCEEEEE
TRDGIAVIDGLDGSEKVVLRAGGFLTEGETIAPQQADAETRTGG
ECCCEEEEECCCCCCEEEEEECCEEECCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA