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The map label for this gene is opuCB [H]

Identifier: 85375187

GI number: 85375187

Start: 2375768

End: 2377321

Strand: Direct

Name: opuCB [H]

Synonym: ELI_11800

Alternate gene names: 85375187

Gene position: 2375768-2377321 (Clockwise)

Preceding gene: 85375186

Following gene: 85375191

Centisome position: 77.83

GC content: 65.7

Gene sequence:

>1554_bases
GTGAACGGAATCTGGGAAACGATGCTCGGCCTCGGCGACAAGCTCGCCGCGCACGTGCTGCTGGCTGCGAGCGCCATTGC
GCTCGGCATTGTCGTCGCTCTGCCGCTGGCGGTCTGGGCCAGCCGCAACACAACCGTCGCGCGCATAACGCTGGGCTTCG
CCAGCCTCGTGCAGACCATCCCCGCGCTGGCCCTGCTGGCGCTGTTCTTCCCGATCCTGCTGAGCCTGCGGGCGATATTC
GGGGAAGGCCTGCCGACGCTCGGCTTCCTGCCCGCGCTGCTGGCGCTGGCGCTCTATGCGCTGCTGCCGATCCTGCGCAA
CGCCGTGACCGCGCGCGACAACATGGCGCCCGGCGTGCTCGAAGCCGCCGACGGCGTCGGCATGTCCAAATGGCAGAAAC
TGCGGCTGGTCGAGGCGCCGCTGGCTGCCCCCTATGTCATGGCCGGGATCCGCACCGCGTCCGTGTGGACCATCGGCGCG
GCGACCCTTTCCACCACCATCGGCCAGCCGAGCCTCGGCGATCCGATCTTTGCCGGGCTGCAGACGCAGAACTGGTCGCT
GGTGCTGGCGGGCTGCCTCTCCTCGGCAGCATTGGCACTGATCGCCGACGCGCTGCTGGGCGCGATCGAGCGCGGTTTCG
CCGAGCGCAAACCATGGCTGGTGTGGGGCGGCGCAGCGGCGGCGGCACTCGGCATCTTCGCTTCGGCCTGGGCGCTCTAC
GGACCCAGCGGCGAAGACGATGACGACACGATAGTGATTGCCGCCAAGCAGTTCTCCGAGCAATATATCCTCGCCCGGCT
GATCGGCGGACAGCTGGAGAAAGCCGGCTACAATATCGAATATCGCGACGGGCTCGGCTCGGCGGTGGTCCACAATGCCG
TCAGCACCGGGGCGATCGATATCTCGATCGATTATACCGGCACGATCTGGACGAACAATTTGGCGCGGCAAGACAATCCG
GGGCGCGACGCAATGTACCGGATCATCAAGCAATGGGAGGCGGAGCAGACCGGCACGCTGGTGCTCGGCAAGCTTGGTTT
CGAGAACGCCTATGGTCTCGGAATGCGCGAGGACCGGGCGGAGAAACTGGGCGTGACCGGCATCGGCGATCTCACACCGA
TAGCCTCACGGTTGGTCACCGGCGGCGATCCCGAATGGTTCGAGCGGCCCGAATGGATCGCGGTGCGCGATGCCTATGGC
CTGGAATTCGCCCGCCAGCGCAATTTCTCGCCCACCTTCATGTACAATGCGCTCAAATCGGGCGAGGCGGATGTGATCAG
CGCCTACACGTCGGACGGACGCATCGCGGCGGACAATATCCGTATTCTCGACGATCCGAAGCAGGCGCTACCGAGTTACG
ATGCGATGATCATGATCGCCCCGGATCGCGCCGACGACGAGCGGCTGATCGCGGCGCTGGAACCGCTACTGGGCGCGATC
GATGTCGAGCTGATGCGCGAAGCCAACCTCTCGGTCGATCGCACAGACGGGCAGAAGATGAGCCCCGATCAGGCCGCCGC
GATGATCGCAGAGCGGATCGGGCTGGAACGCTGA

Upstream 100 bases:

>100_bases
AGACGCCCCGCGCGCTGATCAACGGTGCGGGCGGCGACATCGCGCAGGGCCTCGTCGCGGTGCCGCGCGCCCAAGCGGAT
GCGCTCGCGGGGATGGAGGC

Downstream 100 bases:

>100_bases
CCTAGCGCGCGCGGCGCCAGTTCTGGGTCTGGCAGAACGGGCCGATGCAGCCCTTCACCTCGAGCACGCTTGCGCTCTTG
CGGCGCACGACCGAACGATA

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MNGIWETMLGLGDKLAAHVLLAASAIALGIVVALPLAVWASRNTTVARITLGFASLVQTIPALALLALFFPILLSLRAIF
GEGLPTLGFLPALLALALYALLPILRNAVTARDNMAPGVLEAADGVGMSKWQKLRLVEAPLAAPYVMAGIRTASVWTIGA
ATLSTTIGQPSLGDPIFAGLQTQNWSLVLAGCLSSAALALIADALLGAIERGFAERKPWLVWGGAAAAALGIFASAWALY
GPSGEDDDDTIVIAAKQFSEQYILARLIGGQLEKAGYNIEYRDGLGSAVVHNAVSTGAIDISIDYTGTIWTNNLARQDNP
GRDAMYRIIKQWEAEQTGTLVLGKLGFENAYGLGMREDRAEKLGVTGIGDLTPIASRLVTGGDPEWFERPEWIAVRDAYG
LEFARQRNFSPTFMYNALKSGEADVISAYTSDGRIAADNIRILDDPKQALPSYDAMIMIAPDRADDERLIAALEPLLGAI
DVELMREANLSVDRTDGQKMSPDQAAAMIAERIGLER

Sequences:

>Translated_517_residues
MNGIWETMLGLGDKLAAHVLLAASAIALGIVVALPLAVWASRNTTVARITLGFASLVQTIPALALLALFFPILLSLRAIF
GEGLPTLGFLPALLALALYALLPILRNAVTARDNMAPGVLEAADGVGMSKWQKLRLVEAPLAAPYVMAGIRTASVWTIGA
ATLSTTIGQPSLGDPIFAGLQTQNWSLVLAGCLSSAALALIADALLGAIERGFAERKPWLVWGGAAAAALGIFASAWALY
GPSGEDDDDTIVIAAKQFSEQYILARLIGGQLEKAGYNIEYRDGLGSAVVHNAVSTGAIDISIDYTGTIWTNNLARQDNP
GRDAMYRIIKQWEAEQTGTLVLGKLGFENAYGLGMREDRAEKLGVTGIGDLTPIASRLVTGGDPEWFERPEWIAVRDAYG
LEFARQRNFSPTFMYNALKSGEADVISAYTSDGRIAADNIRILDDPKQALPSYDAMIMIAPDRADDERLIAALEPLLGAI
DVELMREANLSVDRTDGQKMSPDQAAAMIAERIGLER
>Mature_517_residues
MNGIWETMLGLGDKLAAHVLLAASAIALGIVVALPLAVWASRNTTVARITLGFASLVQTIPALALLALFFPILLSLRAIF
GEGLPTLGFLPALLALALYALLPILRNAVTARDNMAPGVLEAADGVGMSKWQKLRLVEAPLAAPYVMAGIRTASVWTIGA
ATLSTTIGQPSLGDPIFAGLQTQNWSLVLAGCLSSAALALIADALLGAIERGFAERKPWLVWGGAAAAALGIFASAWALY
GPSGEDDDDTIVIAAKQFSEQYILARLIGGQLEKAGYNIEYRDGLGSAVVHNAVSTGAIDISIDYTGTIWTNNLARQDNP
GRDAMYRIIKQWEAEQTGTLVLGKLGFENAYGLGMREDRAEKLGVTGIGDLTPIASRLVTGGDPEWFERPEWIAVRDAYG
LEFARQRNFSPTFMYNALKSGEADVISAYTSDGRIAADNIRILDDPKQALPSYDAMIMIAPDRADDERLIAALEPLLGAI
DVELMREANLSVDRTDGQKMSPDQAAAMIAERIGLER

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=198, Percent_Identity=34.3434343434343, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788449, Length=163, Percent_Identity=36.8098159509202, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789033, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788452, Length=273, Percent_Identity=24.1758241758242, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55152; Mature: 55152

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIWETMLGLGDKLAAHVLLAASAIALGIVVALPLAVWASRNTTVARITLGFASLVQTI
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
PALALLALFFPILLSLRAIFGEGLPTLGFLPALLALALYALLPILRNAVTARDNMAPGVL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EAADGVGMSKWQKLRLVEAPLAAPYVMAGIRTASVWTIGAATLSTTIGQPSLGDPIFAGL
HHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHEEEEEHHHHHHHCCCCCCCCHHHCCC
QTQNWSLVLAGCLSSAALALIADALLGAIERGFAERKPWLVWGGAAAAALGIFASAWALY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHC
GPSGEDDDDTIVIAAKQFSEQYILARLIGGQLEKAGYNIEYRDGLGSAVVHNAVSTGAID
CCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHCCCCEEECCCCCHHHHHHHHCCCEEE
ISIDYTGTIWTNNLARQDNPGRDAMYRIIKQWEAEQTGTLVLGKLGFENAYGLGMREDRA
EEEEECEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHH
EKLGVTGIGDLTPIASRLVTGGDPEWFERPEWIAVRDAYGLEFARQRNFSPTFMYNALKS
HHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECHHCHHHHHHCCCCHHHHHHHHCC
GEADVISAYTSDGRIAADNIRILDDPKQALPSYDAMIMIAPDRADDERLIAALEPLLGAI
CCCCEEEEECCCCEEEECCEEEECCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
DVELMREANLSVDRTDGQKMSPDQAAAMIAERIGLER
HHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNGIWETMLGLGDKLAAHVLLAASAIALGIVVALPLAVWASRNTTVARITLGFASLVQTI
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
PALALLALFFPILLSLRAIFGEGLPTLGFLPALLALALYALLPILRNAVTARDNMAPGVL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EAADGVGMSKWQKLRLVEAPLAAPYVMAGIRTASVWTIGAATLSTTIGQPSLGDPIFAGL
HHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHEEEEEHHHHHHHCCCCCCCCHHHCCC
QTQNWSLVLAGCLSSAALALIADALLGAIERGFAERKPWLVWGGAAAAALGIFASAWALY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHC
GPSGEDDDDTIVIAAKQFSEQYILARLIGGQLEKAGYNIEYRDGLGSAVVHNAVSTGAID
CCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHCCCCEEECCCCCHHHHHHHHCCCEEE
ISIDYTGTIWTNNLARQDNPGRDAMYRIIKQWEAEQTGTLVLGKLGFENAYGLGMREDRA
EEEEECEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHH
EKLGVTGIGDLTPIASRLVTGGDPEWFERPEWIAVRDAYGLEFARQRNFSPTFMYNALKS
HHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECHHCHHHHHHCCCCHHHHHHHHCC
GEADVISAYTSDGRIAADNIRILDDPKQALPSYDAMIMIAPDRADDERLIAALEPLLGAI
CCCCEEEEECCCCEEEECCEEEECCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
DVELMREANLSVDRTDGQKMSPDQAAAMIAERIGLER
HHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]