Click here to switch to the map view.

The map label for this gene is dcd

Identifier: 85375122

GI number: 85375122

Start: 2319901

End: 2320455

Strand: Direct

Name: dcd

Synonym: ELI_11475

Alternate gene names: 85375122

Gene position: 2319901-2320455 (Clockwise)

Preceding gene: 85375121

Following gene: 85375123

Centisome position: 76.0

GC content: 60.54

Gene sequence:

>555_bases
ATGGCAATTCTCAGCGACAAGTGGATTCGCGAAGCGGCGCAGACGCGCGGCATGATCGAACCGTTCGAGGAAGCGCAGCG
GCGCGACGGCTGCATTTCCTACGGTCTCAGCTCGTTCGGCTACGACGCCCGCGTCGCACCCGAATTCAAGATCTTCACAA
ACGTCAACAGCGCGGTTGTGGATCCCAAGGATTTCGACGGCGACAGTCTGGTCGACCGTGAGACCGAAGTCTGCATCATC
CCGCCCAACAGCTTCGCGCTGGCCCGCACGGTCGAATATTTCCGCATCCCGGAAGACGTGCTGGTCATCTGTCTCGGCAA
GAGCACCTATGCCCGTTGCGGGATCATTGTGAACGTCACGCCGCTGGAGCCGGGTTGGGAAGGCCATGTGACGCTGGAGT
TTTCCAATACCACGCCGCTCCCGGCCAAAATCTACGCCAATGAAGGCGCGTGCCAATTCCTGTTCCTGCAAGGCAACGAG
CGACCCGAAGTCACCTATGCCGACCGCGCCGGCAAATATATGGGCCAGCGCGGCGTGACGCTGCCGCGTTTATGA

Upstream 100 bases:

>100_bases
GCGCCAAGCAGCTCTGACACAAAGCGCCTCCTCTTCACAGGAGGGGGGTAACATCGGCTTGGCCCTTGCCCCGCCGCGCC
AAGTCCGGAATCACTCGCGC

Downstream 100 bases:

>100_bases
GAATGATCCATGCCACCCGCTCCCTCCACCCTTCCACCCGGATGATAACTCCGGAGTACGATCCGGGTGGAAGGGTGGAG
GGAGCGGGTGGCGCGGCCTT

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MAILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVVDPKDFDGDSLVDRETEVCII
PPNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNE
RPEVTYADRAGKYMGQRGVTLPRL

Sequences:

>Translated_184_residues
MAILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVVDPKDFDGDSLVDRETEVCII
PPNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNE
RPEVTYADRAGKYMGQRGVTLPRL
>Mature_183_residues
AILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVVDPKDFDGDSLVDRETEVCIIP
PNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNER
PEVTYADRAGKYMGQRGVTLPRL

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=160, Percent_Identity=32.5, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_ERYLH (Q2N7F4)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459184.1
- ProteinModelPortal:   Q2N7F4
- SMR:   Q2N7F4
- STRING:   Q2N7F4
- GeneID:   3870404
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_11475
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q2N7F4
- ProtClustDB:   PRK00416
- BioCyc:   ELIT314225:ELI_11475-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20521; Mature: 20389

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVV
CCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEECCHHHCCCCCCCCCCEEEEECCCCEEE
DPKDFDGDSLVDRETEVCIIPPNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVT
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEE
PLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNERPEVTYADRAGKYMGQRGVT
ECCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCEEECCCCCHHHCCCCCC
LPRL
CCCC
>Mature Secondary Structure 
AILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVV
CCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEECCHHHCCCCCCCCCCEEEEECCCCEEE
DPKDFDGDSLVDRETEVCIIPPNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVT
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEE
PLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNERPEVTYADRAGKYMGQRGVT
ECCCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCEEECCCCCHHHCCCCCC
LPRL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA