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The map label for this gene is putA [H]

Identifier: 85375120

GI number: 85375120

Start: 2316111

End: 2319233

Strand: Direct

Name: putA [H]

Synonym: ELI_11465

Alternate gene names: 85375120

Gene position: 2316111-2319233 (Clockwise)

Preceding gene: 85375117

Following gene: 85375121

Centisome position: 75.88

GC content: 65.64

Gene sequence:

>3123_bases
ATGTCCAAGATCGCCCCTTTGAACCGCTTGCATTTCCGGACCGCCTATCGGCAGGAGGAGAATGCCTGCGTTGCCGAACG
GCTTAAACAGGCCGCGCCCGTTTCCGCGCGCCACGAGGAAGCGCAGGCTCTGGCGGTAAGGCTGATCGAAGACGCGCGCA
GCCGCAAGGCGAGCGGGATCGACGCATTCCTGCATACCTATGGCCTCGCGACAGAGGAAGGCATCGCGCTGATGTGTCTT
GCCGAGGCGCTGCTACGCGTGCCCGATCACGAGACCGCCGACGCGCTGATCCGCGACAAGCTGGGCGATATCGACTGGGG
CGAACATCTGGGCGAAAGCTCCTCCACCTTCGTCAACGCGGCGACCTTCTCGCTGATGCTGACCGGCGAAGTGCTGGAAC
GGCCCGAAGAGCACCAACGCGGCATGGGCAAGACGCTGAAGCGGACCGTCAACCGGCTGGGCGAGCCGGTGATCCGCAAG
GCGACGCTGCAGGCGATGCGGATTCTCGGTGGGCAGTTCGTTTATGGCCGCACGATCGGCGAAGCGCTGAAACGCGCCAA
GCCGGAACGGGCGAAGGGCCTGACGCACAGTTTCGACATGCTCGGCGAAGCGGCGATGACCTTCGAAGATGCGGAGCGCT
ACCGCCGGGCCTACGAGCGTGCGATCGAGCGGCTGGCGGGCGAGACCGACGGGACGATCCAGTCGAGCCCCGGTATTTCG
GTCAAGCTGTCGGCGCTCTATCCGAAGTACGACATCTTCCACCAGGATGCCGCGGTCGAGGCGCTGGTGCCGATGTTGCG
CGATCTCGCCATCAAGGCGCGCGATGCCAACATGCACTTCAACATCGATGCCGAGGAAGCCGAGCGGCTTGAGATTTCGC
TCGATATCATTGAGCGGCTGGCGGCGGACGATGCGCTGTTTACTAAGGCCGACGGCACCCGCTGGGACGGCTTCGGCCTC
GCCATCCAGGCCTATCAGAAACGCGCCGCGCCGCTGTGCGACTGGATCGTCAAGCTCGCCCGGCGGCATGATCGCCGCTT
CATGGTGCGTCTGGTCAAAGGCGCGTATTGGGACACCGAGATCAAGCTGAGCCAGGTCGGCGGCTACGAGGACTTCCCGG
TTTTCACCCGCAAGGTGGCGACAGATGTTTCCTACCTCGCCTGCGCTGCGAAACTGCTCGAAGCGCCCGACGCGATCTAT
CCGGCCTTCGCGACACACAACGCCTATACGGTCGGCGCGGTAAAGGCTCTTGCAGGACATACCGAGTTCGAGTTCCAGCG
CTTGCACGGCATGGGCGAAGAGTTGTTCGAAGCGCTTGCCGCGCAGGAGGGCAACCGCAAGACACCGGTACGCATCTACG
CGCCGGTCGGCGTGCACAAGGACCTGCTGGCCTATCTCGTCCGCCGCCTGCTGGAAAACGGCGCCAACTCCTCCTTCGTC
AACCGCATGGCCGATGCCGAAGTACCGGCGGTGGAACTCGCCAACGACCCGGTCGAGGAGCTCGCACTGCTCGAGCCCAA
GCGCAATCCGGACATCCCGCTCCCGGCGGATATTTTCCCGGGGCGGCGCAACAGCATCGGTGTCGACCTCGCCGATCCGC
TCGTGCGCGATCCGCTGCTGCAGCGGCTCGAGGCGCTCGAAAGCAGGCACTGGTATGCCGGGCCGACCTTCCCGTCCGAA
GACGCGGGCGAGGAAGCGCCGATCAATGCGCCGCAGGACCTGACGCACGAAGTTGGCACGCGCCGCGATTCGACCGAAGA
GGAAGTGCGCGCGGCCATCACGCAGGCCGAATTCATCCAGCCGGGGTGGAACGCCCTCGGCGGCGAGAAGCGAGCCGTGC
TGCTCGAAGCCGCCGCCGACCTGTTCGAAGACCACATGGACGAATTCCTCAGCCTGTGTCGGCGCGAGGCGGGGAAGACC
GTGCTCGACGGCGTGCTGGAGGTTCGCGAGGCGGTCGACTTCCTGCGCTATTACGCCACCGAAGCGCGGCGGCAATTCAG
CGCCCCGATCATGCTGCCGGGTCCGACCGGCGAGGAAAACCGCCTGCATCTTGCCGGGCGCGGCGTATTCGCAACCATCA
GCCCGTGGAACTTCCCGCTGGCAATCTTCATCGGCCCTGCCGCCGCCGCGATGGCGGCGGGCAATACCGTCATCGCCAAG
CCCGCCGAGCAGACCCCACTGATCGCCGCGCTGGCGGTGAAGCTATGCCACGAGGCGGGTATTCCCGAGGAAGTCTTCCA
GCTCCTCCCGGGGGCGGGCGATGTCGGGCAGATGATTACCGGCGATCCGCGCATAGCAGGGGTCGCCTTTACCGGCTCGA
CCGAGACCGCGCAGGCGATCAACCGCTCGCTCGCCGCACGCGAAGGGCCGATCGCGACGTTTATCGCCGAAACCGGTGGG
CAGAACGCCATGATCGTCGACAGTTCTGCCTTGCCCGAACAGGTCGCGCGCGATGTCGTCGCCAGCGCGTTCCAGAGCGC
CGGCCAGCGCTGTTCGGCCCAGCGCATGCTCTACATCCAGGACGACGTATACGACGACATGCTGGCGATGATCCGCGGCG
CGTTCGCAGCATTGCAGATCGGCGATCCGACCGATTTCGCCATCGATGTCGGCCCGGTGATCGATCCCGATGCCAAGGCT
GCGCTCGAACGCCATGTCGCGCGGCGCAAGAAGGCCGGGCGCACGGTGTGGCGGCGCAAGCTTCCGCGCGGCACCGCCAA
CGGCTGCTTCGTCGCGCCAACCATTATCGAGCTCGACTCGATCCTCGATCTGAAGCGCGAGAATTTCGGGCCGATCCTGC
ACGTTGCGCGCTACAAGGCCGACGGGCTCAACCGGGTCATCGCGGACATCAATTCGACCGGCTATGGCCTGACGTTGGGC
CTGCACAGCCGCATCGAAGCGACGCGCCGTTATGTAGAAGCGCGCGCGCGGGTCGGCAATTTCTACGTCAACCGCAACCA
GATCGGCGCGGTGGTGGAAAGCCAGCCCTTCGGCGGCGAGGGTCTGTCGGGCACCGGCCCCAAGGCGGGCGGCCCGCATT
ATGTCGCCCGCTTTGCGACCGAGCGGGTAGTCTGTATCGACACCACGGCTGCGGGCGGCAACGCAACACTGCTGGCGAGT
TAG

Upstream 100 bases:

>100_bases
GGATCGAACCGGCTTGGCGACTTTCCTTGAATGATACGCTCTTCGGGTCCAATTCGCTGCGATGGACACGACTCGCCACA
GGAGAAAATCGACCACCCCT

Downstream 100 bases:

>100_bases
CGACGGCCGACCAAGAGGGGGGTTCGCAAGGCGGCGCTGAATGATTATACAGCGCCGCCATGGGCCGATTCCTCAAGCTT
TTCATCGCAATATTCGCTCT

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1040; Mature: 1039

Protein sequence:

>1040_residues
MSKIAPLNRLHFRTAYRQEENACVAERLKQAAPVSARHEEAQALAVRLIEDARSRKASGIDAFLHTYGLATEEGIALMCL
AEALLRVPDHETADALIRDKLGDIDWGEHLGESSSTFVNAATFSLMLTGEVLERPEEHQRGMGKTLKRTVNRLGEPVIRK
ATLQAMRILGGQFVYGRTIGEALKRAKPERAKGLTHSFDMLGEAAMTFEDAERYRRAYERAIERLAGETDGTIQSSPGIS
VKLSALYPKYDIFHQDAAVEALVPMLRDLAIKARDANMHFNIDAEEAERLEISLDIIERLAADDALFTKADGTRWDGFGL
AIQAYQKRAAPLCDWIVKLARRHDRRFMVRLVKGAYWDTEIKLSQVGGYEDFPVFTRKVATDVSYLACAAKLLEAPDAIY
PAFATHNAYTVGAVKALAGHTEFEFQRLHGMGEELFEALAAQEGNRKTPVRIYAPVGVHKDLLAYLVRRLLENGANSSFV
NRMADAEVPAVELANDPVEELALLEPKRNPDIPLPADIFPGRRNSIGVDLADPLVRDPLLQRLEALESRHWYAGPTFPSE
DAGEEAPINAPQDLTHEVGTRRDSTEEEVRAAITQAEFIQPGWNALGGEKRAVLLEAAADLFEDHMDEFLSLCRREAGKT
VLDGVLEVREAVDFLRYYATEARRQFSAPIMLPGPTGEENRLHLAGRGVFATISPWNFPLAIFIGPAAAAMAAGNTVIAK
PAEQTPLIAALAVKLCHEAGIPEEVFQLLPGAGDVGQMITGDPRIAGVAFTGSTETAQAINRSLAAREGPIATFIAETGG
QNAMIVDSSALPEQVARDVVASAFQSAGQRCSAQRMLYIQDDVYDDMLAMIRGAFAALQIGDPTDFAIDVGPVIDPDAKA
ALERHVARRKKAGRTVWRRKLPRGTANGCFVAPTIIELDSILDLKRENFGPILHVARYKADGLNRVIADINSTGYGLTLG
LHSRIEATRRYVEARARVGNFYVNRNQIGAVVESQPFGGEGLSGTGPKAGGPHYVARFATERVVCIDTTAAGGNATLLAS

Sequences:

>Translated_1040_residues
MSKIAPLNRLHFRTAYRQEENACVAERLKQAAPVSARHEEAQALAVRLIEDARSRKASGIDAFLHTYGLATEEGIALMCL
AEALLRVPDHETADALIRDKLGDIDWGEHLGESSSTFVNAATFSLMLTGEVLERPEEHQRGMGKTLKRTVNRLGEPVIRK
ATLQAMRILGGQFVYGRTIGEALKRAKPERAKGLTHSFDMLGEAAMTFEDAERYRRAYERAIERLAGETDGTIQSSPGIS
VKLSALYPKYDIFHQDAAVEALVPMLRDLAIKARDANMHFNIDAEEAERLEISLDIIERLAADDALFTKADGTRWDGFGL
AIQAYQKRAAPLCDWIVKLARRHDRRFMVRLVKGAYWDTEIKLSQVGGYEDFPVFTRKVATDVSYLACAAKLLEAPDAIY
PAFATHNAYTVGAVKALAGHTEFEFQRLHGMGEELFEALAAQEGNRKTPVRIYAPVGVHKDLLAYLVRRLLENGANSSFV
NRMADAEVPAVELANDPVEELALLEPKRNPDIPLPADIFPGRRNSIGVDLADPLVRDPLLQRLEALESRHWYAGPTFPSE
DAGEEAPINAPQDLTHEVGTRRDSTEEEVRAAITQAEFIQPGWNALGGEKRAVLLEAAADLFEDHMDEFLSLCRREAGKT
VLDGVLEVREAVDFLRYYATEARRQFSAPIMLPGPTGEENRLHLAGRGVFATISPWNFPLAIFIGPAAAAMAAGNTVIAK
PAEQTPLIAALAVKLCHEAGIPEEVFQLLPGAGDVGQMITGDPRIAGVAFTGSTETAQAINRSLAAREGPIATFIAETGG
QNAMIVDSSALPEQVARDVVASAFQSAGQRCSAQRMLYIQDDVYDDMLAMIRGAFAALQIGDPTDFAIDVGPVIDPDAKA
ALERHVARRKKAGRTVWRRKLPRGTANGCFVAPTIIELDSILDLKRENFGPILHVARYKADGLNRVIADINSTGYGLTLG
LHSRIEATRRYVEARARVGNFYVNRNQIGAVVESQPFGGEGLSGTGPKAGGPHYVARFATERVVCIDTTAAGGNATLLAS
>Mature_1039_residues
SKIAPLNRLHFRTAYRQEENACVAERLKQAAPVSARHEEAQALAVRLIEDARSRKASGIDAFLHTYGLATEEGIALMCLA
EALLRVPDHETADALIRDKLGDIDWGEHLGESSSTFVNAATFSLMLTGEVLERPEEHQRGMGKTLKRTVNRLGEPVIRKA
TLQAMRILGGQFVYGRTIGEALKRAKPERAKGLTHSFDMLGEAAMTFEDAERYRRAYERAIERLAGETDGTIQSSPGISV
KLSALYPKYDIFHQDAAVEALVPMLRDLAIKARDANMHFNIDAEEAERLEISLDIIERLAADDALFTKADGTRWDGFGLA
IQAYQKRAAPLCDWIVKLARRHDRRFMVRLVKGAYWDTEIKLSQVGGYEDFPVFTRKVATDVSYLACAAKLLEAPDAIYP
AFATHNAYTVGAVKALAGHTEFEFQRLHGMGEELFEALAAQEGNRKTPVRIYAPVGVHKDLLAYLVRRLLENGANSSFVN
RMADAEVPAVELANDPVEELALLEPKRNPDIPLPADIFPGRRNSIGVDLADPLVRDPLLQRLEALESRHWYAGPTFPSED
AGEEAPINAPQDLTHEVGTRRDSTEEEVRAAITQAEFIQPGWNALGGEKRAVLLEAAADLFEDHMDEFLSLCRREAGKTV
LDGVLEVREAVDFLRYYATEARRQFSAPIMLPGPTGEENRLHLAGRGVFATISPWNFPLAIFIGPAAAAMAAGNTVIAKP
AEQTPLIAALAVKLCHEAGIPEEVFQLLPGAGDVGQMITGDPRIAGVAFTGSTETAQAINRSLAAREGPIATFIAETGGQ
NAMIVDSSALPEQVARDVVASAFQSAGQRCSAQRMLYIQDDVYDDMLAMIRGAFAALQIGDPTDFAIDVGPVIDPDAKAA
LERHVARRKKAGRTVWRRKLPRGTANGCFVAPTIIELDSILDLKRENFGPILHVARYKADGLNRVIADINSTGYGLTLGL
HSRIEATRRYVEARARVGNFYVNRNQIGAVVESQPFGGEGLSGTGPKAGGPHYVARFATERVVCIDTTAAGGNATLLAS

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=478, Percent_Identity=31.1715481171548, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI25777734, Length=478, Percent_Identity=31.1715481171548, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI238859541, Length=478, Percent_Identity=31.1715481171548, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI21614513, Length=416, Percent_Identity=29.3269230769231, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI12007648, Length=457, Percent_Identity=29.3216630196937, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI238814322, Length=419, Percent_Identity=28.8782816229117, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI153266822, Length=435, Percent_Identity=29.8850574712644, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI21361176, Length=484, Percent_Identity=28.7190082644628, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=26.9978401727862, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI25777732, Length=438, Percent_Identity=28.5388127853881, Blast_Score=150, Evalue=8e-36,
Organism=Homo sapiens, GI4507229, Length=437, Percent_Identity=29.2906178489703, Blast_Score=146, Evalue=9e-35,
Organism=Homo sapiens, GI25777724, Length=419, Percent_Identity=27.9236276849642, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI25777730, Length=412, Percent_Identity=29.126213592233, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777728, Length=412, Percent_Identity=28.1553398058252, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI25777721, Length=450, Percent_Identity=29.1111111111111, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI188035924, Length=418, Percent_Identity=27.9904306220096, Blast_Score=136, Evalue=9e-32,
Organism=Homo sapiens, GI310128093, Length=418, Percent_Identity=27.9904306220096, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310128103, Length=418, Percent_Identity=27.9904306220096, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI310128091, Length=385, Percent_Identity=28.8311688311688, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI25952152, Length=455, Percent_Identity=26.5934065934066, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI11095441, Length=420, Percent_Identity=27.3809523809524, Blast_Score=120, Evalue=8e-27,
Organism=Homo sapiens, GI25777726, Length=418, Percent_Identity=24.6411483253589, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=27.0516717325228, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI310128087, Length=241, Percent_Identity=28.6307053941909, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=26.1398176291793, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=26.1398176291793, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI71773324, Length=329, Percent_Identity=26.1398176291793, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI301500698, Length=271, Percent_Identity=26.5682656826568, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI206597441, Length=342, Percent_Identity=23.9766081871345, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI206597439, Length=342, Percent_Identity=23.9766081871345, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI22907049, Length=342, Percent_Identity=23.9766081871345, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=24.8484848484848, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=24.8484848484848, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI310128097, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI310128099, Length=191, Percent_Identity=27.7486910994764, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI310128101, Length=189, Percent_Identity=27.5132275132275, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI223972651, Length=275, Percent_Identity=28, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1787250, Length=1052, Percent_Identity=48.7642585551331, Blast_Score=911, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=504, Percent_Identity=32.1428571428571, Blast_Score=199, Evalue=7e-52,
Organism=Escherichia coli, GI87081896, Length=466, Percent_Identity=30.4721030042918, Blast_Score=180, Evalue=5e-46,
Organism=Escherichia coli, GI1787684, Length=453, Percent_Identity=31.3465783664459, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI1787715, Length=458, Percent_Identity=31.2227074235808, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787558, Length=442, Percent_Identity=28.7330316742081, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1788042, Length=435, Percent_Identity=29.6551724137931, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1786504, Length=439, Percent_Identity=27.7904328018223, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87082295, Length=441, Percent_Identity=27.6643990929705, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI87081926, Length=412, Percent_Identity=27.4271844660194, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1787653, Length=334, Percent_Identity=23.6526946107784, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17534447, Length=466, Percent_Identity=31.1158798283262, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=457, Percent_Identity=30.8533916849015, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=402, Percent_Identity=32.089552238806, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17562198, Length=434, Percent_Identity=31.7972350230415, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI133930964, Length=431, Percent_Identity=30.3944315545244, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI25144435, Length=433, Percent_Identity=30.2540415704388, Blast_Score=159, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=405, Percent_Identity=30.8641975308642, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17551164, Length=457, Percent_Identity=27.7899343544858, Blast_Score=146, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=546, Percent_Identity=25.8241758241758, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=443, Percent_Identity=26.6365688487585, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71995606, Length=418, Percent_Identity=27.511961722488, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32564151, Length=408, Percent_Identity=29.1666666666667, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534119, Length=473, Percent_Identity=25.5813953488372, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=375, Percent_Identity=26.9333333333333, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=414, Percent_Identity=26.8115942028986, Blast_Score=116, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=29.4701986754967, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI25146391, Length=404, Percent_Identity=23.7623762376238, Blast_Score=83, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=386, Percent_Identity=23.8341968911917, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566756, Length=386, Percent_Identity=23.8341968911917, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564084, Length=324, Percent_Identity=25.6172839506173, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320917, Length=441, Percent_Identity=30.6122448979592, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6325196, Length=471, Percent_Identity=30.7855626326964, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=444, Percent_Identity=29.5045045045045, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6323821, Length=428, Percent_Identity=28.7383177570093, Blast_Score=147, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6323822, Length=426, Percent_Identity=28.169014084507, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321826, Length=491, Percent_Identity=28.1059063136456, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319478, Length=406, Percent_Identity=28.3251231527094, Blast_Score=137, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6321828, Length=482, Percent_Identity=25.7261410788382, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323757, Length=415, Percent_Identity=24.578313253012, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362580, Length=434, Percent_Identity=32.0276497695853, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI62472918, Length=434, Percent_Identity=32.0276497695853, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI62472926, Length=434, Percent_Identity=32.0276497695853, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI62472936, Length=434, Percent_Identity=32.0276497695853, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI21356737, Length=434, Percent_Identity=32.0276497695853, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24668425, Length=468, Percent_Identity=29.0598290598291, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668417, Length=468, Percent_Identity=29.0598290598291, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668413, Length=468, Percent_Identity=29.0598290598291, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20129399, Length=412, Percent_Identity=29.126213592233, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24650465, Length=412, Percent_Identity=28.8834951456311, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24585660, Length=420, Percent_Identity=26.9047619047619, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571798, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571796, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571794, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571806, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571802, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571800, Length=480, Percent_Identity=25.8333333333333, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666674, Length=484, Percent_Identity=27.0661157024793, Blast_Score=131, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574525, Length=470, Percent_Identity=23.4042553191489, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24638878, Length=388, Percent_Identity=26.5463917525773, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638876, Length=388, Percent_Identity=26.5463917525773, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360299, Length=336, Percent_Identity=25.297619047619, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360297, Length=336, Percent_Identity=25.297619047619, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360295, Length=336, Percent_Identity=25.297619047619, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24586250, Length=336, Percent_Identity=25.297619047619, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360303, Length=332, Percent_Identity=25.3012048192771, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552499, Length=336, Percent_Identity=25.297619047619, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360301, Length=332, Percent_Identity=25.3012048192771, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 113576; Mature: 113445

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAPLNRLHFRTAYRQEENACVAERLKQAAPVSARHEEAQALAVRLIEDARSRKASGI
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
DAFLHTYGLATEEGIALMCLAEALLRVPDHETADALIRDKLGDIDWGEHLGESSSTFVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEH
ATFSLMLTGEVLERPEEHQRGMGKTLKRTVNRLGEPVIRKATLQAMRILGGQFVYGRTIG
HHHEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEHHHHH
EALKRAKPERAKGLTHSFDMLGEAAMTFEDAERYRRAYERAIERLAGETDGTIQSSPGIS
HHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCE
VKLSALYPKYDIFHQDAAVEALVPMLRDLAIKARDANMHFNIDAEEAERLEISLDIIERL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHHHHHHH
AADDALFTKADGTRWDGFGLAIQAYQKRAAPLCDWIVKLARRHDRRFMVRLVKGAYWDTE
HCCCCEEECCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IKLSQVGGYEDFPVFTRKVATDVSYLACAAKLLEAPDAIYPAFATHNAYTVGAVKALAGH
EEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHCCCCEEHHHHHHHHCC
TEFEFQRLHGMGEELFEALAAQEGNRKTPVRIYAPVGVHKDLLAYLVRRLLENGANSSFV
CHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
NRMADAEVPAVELANDPVEELALLEPKRNPDIPLPADIFPGRRNSIGVDLADPLVRDPLL
HHHHCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
QRLEALESRHWYAGPTFPSEDAGEEAPINAPQDLTHEVGTRRDSTEEEVRAAITQAEFIQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PGWNALGGEKRAVLLEAAADLFEDHMDEFLSLCRREAGKTVLDGVLEVREAVDFLRYYAT
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
EARRQFSAPIMLPGPTGEENRLHLAGRGVFATISPWNFPLAIFIGPAAAAMAAGNTVIAK
HHHHHHCCCEECCCCCCCCCEEEEECCCEEEEECCCCCCEEEEECCHHHHHHCCCEEEEC
PAEQTPLIAALAVKLCHEAGIPEEVFQLLPGAGDVGQMITGDPRIAGVAFTGSTETAQAI
CCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHH
NRSLAAREGPIATFIAETGGQNAMIVDSSALPEQVARDVVASAFQSAGQRCSAQRMLYIQ
HHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DDVYDDMLAMIRGAFAALQIGDPTDFAIDVGPVIDPDAKAALERHVARRKKAGRTVWRRK
HHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LPRGTANGCFVAPTIIELDSILDLKRENFGPILHVARYKADGLNRVIADINSTGYGLTLG
CCCCCCCCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCCCCEEEEC
LHSRIEATRRYVEARARVGNFYVNRNQIGAVVESQPFGGEGLSGTGPKAGGPHYVARFAT
HHHHHHHHHHHHHHHHHHHHEEEECCHHCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHC
ERVVCIDTTAAGGNATLLAS
CEEEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
SKIAPLNRLHFRTAYRQEENACVAERLKQAAPVSARHEEAQALAVRLIEDARSRKASGI
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
DAFLHTYGLATEEGIALMCLAEALLRVPDHETADALIRDKLGDIDWGEHLGESSSTFVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEEH
ATFSLMLTGEVLERPEEHQRGMGKTLKRTVNRLGEPVIRKATLQAMRILGGQFVYGRTIG
HHHEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEHHHHH
EALKRAKPERAKGLTHSFDMLGEAAMTFEDAERYRRAYERAIERLAGETDGTIQSSPGIS
HHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCE
VKLSALYPKYDIFHQDAAVEALVPMLRDLAIKARDANMHFNIDAEEAERLEISLDIIERL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHHHHHHH
AADDALFTKADGTRWDGFGLAIQAYQKRAAPLCDWIVKLARRHDRRFMVRLVKGAYWDTE
HCCCCEEECCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IKLSQVGGYEDFPVFTRKVATDVSYLACAAKLLEAPDAIYPAFATHNAYTVGAVKALAGH
EEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHCCCCEEHHHHHHHHCC
TEFEFQRLHGMGEELFEALAAQEGNRKTPVRIYAPVGVHKDLLAYLVRRLLENGANSSFV
CHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
NRMADAEVPAVELANDPVEELALLEPKRNPDIPLPADIFPGRRNSIGVDLADPLVRDPLL
HHHHCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
QRLEALESRHWYAGPTFPSEDAGEEAPINAPQDLTHEVGTRRDSTEEEVRAAITQAEFIQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PGWNALGGEKRAVLLEAAADLFEDHMDEFLSLCRREAGKTVLDGVLEVREAVDFLRYYAT
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
EARRQFSAPIMLPGPTGEENRLHLAGRGVFATISPWNFPLAIFIGPAAAAMAAGNTVIAK
HHHHHHCCCEECCCCCCCCCEEEEECCCEEEEECCCCCCEEEEECCHHHHHHCCCEEEEC
PAEQTPLIAALAVKLCHEAGIPEEVFQLLPGAGDVGQMITGDPRIAGVAFTGSTETAQAI
CCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHH
NRSLAAREGPIATFIAETGGQNAMIVDSSALPEQVARDVVASAFQSAGQRCSAQRMLYIQ
HHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DDVYDDMLAMIRGAFAALQIGDPTDFAIDVGPVIDPDAKAALERHVARRKKAGRTVWRRK
HHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LPRGTANGCFVAPTIIELDSILDLKRENFGPILHVARYKADGLNRVIADINSTGYGLTLG
CCCCCCCCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCCCCEEEEC
LHSRIEATRRYVEARARVGNFYVNRNQIGAVVESQPFGGEGLSGTGPKAGGPHYVARFAT
HHHHHHHHHHHHHHHHHHHHEEEECCHHCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHC
ERVVCIDTTAAGGNATLLAS
CEEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]