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The map label for this gene is cirA [H]

Identifier: 85374965

GI number: 85374965

Start: 2164416

End: 2166959

Strand: Direct

Name: cirA [H]

Synonym: ELI_10690

Alternate gene names: 85374965

Gene position: 2164416-2166959 (Clockwise)

Preceding gene: 85374964

Following gene: 85374966

Centisome position: 70.91

GC content: 58.49

Gene sequence:

>2544_bases
GTGCCGGCACATGCCCAGGACGCTGCATCGCAGGGCGAAAAGCCCGAGGCGCAGGAAGGTGACCTTGAGACAATCGTCGT
CACGGCGCAGAAGCGCGAACAGAATTTGCAGGATGTTCCGGCCGCCGTTTCCGCCATAGGCGGCGAGACGCTGCGCACGC
GCGGCATCACGGAGACCTCAGACTTGATGGGCGCGATCCCCAGCCTGCAAGTCACCACTCCCTATGGTCGCACCCAACCG
AATTTCTCGCTGCGCGGGATTTCAGTGGCGAACGAATTTTCCGCCTCCACTGCGTCGCCGGTTGGCGTCTATGTCGATGA
AGTCTATCAGAGCTTCCGGGCGAGCCATGGCCTGCAACTCTATGACATCGACCGGGTCGAGGTACTGCGCGGACCGCAAG
GAACACTCTACGGTCGCAACACCACGGGTGGCGCGATCAGCTTCTTCACGCGCAAGCCGGATCTGGGAGAGGCCAATGGC
TATCTGACCGCCGGCTATGCCAATTACGACACTTTCACGGTGCAGGGCGCCGCTGAAGCGACGCTGGTTCCCGACATCTT
GGGCGTCCGCGTCGCCGGTACTTTTGCAAAAGGGGATGGTTGGCAGCGCAATGTACTGCCTGGGAATGAGCGCGACCTAG
GGACCACCGATACGATCGGCGGTCGCATCTCGATCCGCTTCCGGCCCGATCCCGATCTCGACATCAATTTGAAGCTCTAT
GCCGCGAAGGACGATCCATGGGGCACCGCGCCCTATGCAGGTGGTCAACTCGCGGGCGGGCAGGATGCGCTCGGCTATTC
GCGTTACGATCCGCAACCTTTCCTAGGCGGGCGGTTGCTGCGTGACAATGAGGTCGCAGTTGATCGGGTAGGTAAGAACA
TCAGCAAGTCGAAAGGGATAGCCCTCAACATCAAATGGGATGTCAGCGACCAATTCTCCGTCACCTCGATTACCGGCTAC
GACACCGGCGACTATATCAACAATCCTGATGATTGCGATGGCGGCCCAGCCGATCTCTGCTCGATCGGCCTCACGTCGAC
GAGCAAGAATTTCAACCAGGATCTGCGTTTCAGCTATTCGAACGACCGCCTCGATATCATTGCCGGCCTTTATTATGGCA
GGGACAAGGTCAAGACGGTCAACTACCCGGACTTTTTCGGGGCGCTGAGGCCGCTGCTGCTTGGCGCCGGTCTTCCGGGC
AGCTACAATAACGCCGCAATCGGAACGCCCGACGCGATCCGCTATATCCCAGCCTTTGCCGCCAATCCGGCGTTGGGGCC
TGGCGATGCCGGATTCTGCGACGCGATCGAGATCAATCCCAACGGCTTCCTTGATGCACGCTCGCTGATTGCACTCCAGA
CCGACATCGCGATCAATAATACGGGCAATGGCGGCATGGGGGGTAGCTTTTCGGCGGGCTGCGCCGGGGCAGGCGCGCCT
CCGTTCACCCCGATCCTCGGCGAACAGCGTTTTGACGTGTCGCGCCCCTCGAAGGCGATCTACGGCGACGTAACCTGGAA
AACGACCGAGCGGCTGACCGTGGCGGTGGGTGCACGCTACACCCAGGATAAGGTCAATTACCTTAACGGCAGCACTTTCC
TCTATGCGCTCGACGGTACGACGCCGGTTGTCAACCTGATCCCCTACAGCAATCCATACAACCCCAATCTCGCGCCGCTT
GAGCAGCGCGAAAAGGCAAACAGGCTAACCGGCCGTATCAATGTCAGCTATGAGTTCGCCGATGATATCATGGGCTATCT
CCAGTACAGTCGCGGTTACCGCAGCGGCAGCTTCAACGGGCTTGCCTATCAGGGCGTCAATCAAGTCTATTATATCCAGC
CTGAAAAGGTGAATGCATATGAGGCGGGGCTCAAAACCCGGCTGTTCGATCGCCGCGTCCAACTTAACCTCGCGGGCTTC
TACTACGAGTATTCGAATCACCAAGTAACGCAGGCGGTTGGCGCTACAACCTTCACGCGCAGCGCCAATGGTCGCCTGTT
CGGTGGCGAGGCCGAACTCGCCTGGCAGGTGGCCGATACGTTGCGTTTCGATGCTTCGCTGGGCTATCTCAACAGCAAGT
ACAAAGGCAATGTGATCGATCCGGCAAACCCGGCAAGCCCGACATTGAACGTCAACGGCAATCCCTTCCCGAACGCGCCG
GAGGTTACGTTCCAGGCCGGATTCGACTGGGATATGATCGATGACGGCACCAACAAGCTGACCTTGCGCGGTGATGCGTC
CTACATGGGCAAGTACTATTTTGATCCGTTCAAGAATTATGGGCAGACACCGTGCGATACACCCCCAGCGGGATCGAACA
TAACGCTCGCGGGTAAGGCGATTACATGCGCAAATCCGGGCTACTGGCTCGCCAATGCGCGATTAACCTATGCGCACGAC
AATATGTCGGTTAGCTTGTGGGCGAAGAATCTGTTCGACAAATATTACTACACCTACGGCCTCAACCTCAACGTGTTCGG
CTACGATTATCTGAACCGCGGCATGCCGCGCACTTATGGCGTCGAAGCGACAGTCAAGTTCTGA

Upstream 100 bases:

>100_bases
CGCCAAATCAAAAAATGCCGTGGGGAGGACAGTCATGGTCACAGCCTTTAGGACAAATTTGCTTTGTGCCACCGCGCTAT
CGATCGCGTGTGCGCTTGCA

Downstream 100 bases:

>100_bases
TCGCTGCTGCGACGGGGGCGGCGGGCATCCTCTCCCGCCCGCTGCCCCCGATTTTTCGACCTGACTTTCAGACCGAGGAG
CATCCATGATGCGTTCCACC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 846

Protein sequence:

>847_residues
MPAHAQDAASQGEKPEAQEGDLETIVVTAQKREQNLQDVPAAVSAIGGETLRTRGITETSDLMGAIPSLQVTTPYGRTQP
NFSLRGISVANEFSASTASPVGVYVDEVYQSFRASHGLQLYDIDRVEVLRGPQGTLYGRNTTGGAISFFTRKPDLGEANG
YLTAGYANYDTFTVQGAAEATLVPDILGVRVAGTFAKGDGWQRNVLPGNERDLGTTDTIGGRISIRFRPDPDLDINLKLY
AAKDDPWGTAPYAGGQLAGGQDALGYSRYDPQPFLGGRLLRDNEVAVDRVGKNISKSKGIALNIKWDVSDQFSVTSITGY
DTGDYINNPDDCDGGPADLCSIGLTSTSKNFNQDLRFSYSNDRLDIIAGLYYGRDKVKTVNYPDFFGALRPLLLGAGLPG
SYNNAAIGTPDAIRYIPAFAANPALGPGDAGFCDAIEINPNGFLDARSLIALQTDIAINNTGNGGMGGSFSAGCAGAGAP
PFTPILGEQRFDVSRPSKAIYGDVTWKTTERLTVAVGARYTQDKVNYLNGSTFLYALDGTTPVVNLIPYSNPYNPNLAPL
EQREKANRLTGRINVSYEFADDIMGYLQYSRGYRSGSFNGLAYQGVNQVYYIQPEKVNAYEAGLKTRLFDRRVQLNLAGF
YYEYSNHQVTQAVGATTFTRSANGRLFGGEAELAWQVADTLRFDASLGYLNSKYKGNVIDPANPASPTLNVNGNPFPNAP
EVTFQAGFDWDMIDDGTNKLTLRGDASYMGKYYFDPFKNYGQTPCDTPPAGSNITLAGKAITCANPGYWLANARLTYAHD
NMSVSLWAKNLFDKYYYTYGLNLNVFGYDYLNRGMPRTYGVEATVKF

Sequences:

>Translated_847_residues
MPAHAQDAASQGEKPEAQEGDLETIVVTAQKREQNLQDVPAAVSAIGGETLRTRGITETSDLMGAIPSLQVTTPYGRTQP
NFSLRGISVANEFSASTASPVGVYVDEVYQSFRASHGLQLYDIDRVEVLRGPQGTLYGRNTTGGAISFFTRKPDLGEANG
YLTAGYANYDTFTVQGAAEATLVPDILGVRVAGTFAKGDGWQRNVLPGNERDLGTTDTIGGRISIRFRPDPDLDINLKLY
AAKDDPWGTAPYAGGQLAGGQDALGYSRYDPQPFLGGRLLRDNEVAVDRVGKNISKSKGIALNIKWDVSDQFSVTSITGY
DTGDYINNPDDCDGGPADLCSIGLTSTSKNFNQDLRFSYSNDRLDIIAGLYYGRDKVKTVNYPDFFGALRPLLLGAGLPG
SYNNAAIGTPDAIRYIPAFAANPALGPGDAGFCDAIEINPNGFLDARSLIALQTDIAINNTGNGGMGGSFSAGCAGAGAP
PFTPILGEQRFDVSRPSKAIYGDVTWKTTERLTVAVGARYTQDKVNYLNGSTFLYALDGTTPVVNLIPYSNPYNPNLAPL
EQREKANRLTGRINVSYEFADDIMGYLQYSRGYRSGSFNGLAYQGVNQVYYIQPEKVNAYEAGLKTRLFDRRVQLNLAGF
YYEYSNHQVTQAVGATTFTRSANGRLFGGEAELAWQVADTLRFDASLGYLNSKYKGNVIDPANPASPTLNVNGNPFPNAP
EVTFQAGFDWDMIDDGTNKLTLRGDASYMGKYYFDPFKNYGQTPCDTPPAGSNITLAGKAITCANPGYWLANARLTYAHD
NMSVSLWAKNLFDKYYYTYGLNLNVFGYDYLNRGMPRTYGVEATVKF
>Mature_846_residues
PAHAQDAASQGEKPEAQEGDLETIVVTAQKREQNLQDVPAAVSAIGGETLRTRGITETSDLMGAIPSLQVTTPYGRTQPN
FSLRGISVANEFSASTASPVGVYVDEVYQSFRASHGLQLYDIDRVEVLRGPQGTLYGRNTTGGAISFFTRKPDLGEANGY
LTAGYANYDTFTVQGAAEATLVPDILGVRVAGTFAKGDGWQRNVLPGNERDLGTTDTIGGRISIRFRPDPDLDINLKLYA
AKDDPWGTAPYAGGQLAGGQDALGYSRYDPQPFLGGRLLRDNEVAVDRVGKNISKSKGIALNIKWDVSDQFSVTSITGYD
TGDYINNPDDCDGGPADLCSIGLTSTSKNFNQDLRFSYSNDRLDIIAGLYYGRDKVKTVNYPDFFGALRPLLLGAGLPGS
YNNAAIGTPDAIRYIPAFAANPALGPGDAGFCDAIEINPNGFLDARSLIALQTDIAINNTGNGGMGGSFSAGCAGAGAPP
FTPILGEQRFDVSRPSKAIYGDVTWKTTERLTVAVGARYTQDKVNYLNGSTFLYALDGTTPVVNLIPYSNPYNPNLAPLE
QREKANRLTGRINVSYEFADDIMGYLQYSRGYRSGSFNGLAYQGVNQVYYIQPEKVNAYEAGLKTRLFDRRVQLNLAGFY
YEYSNHQVTQAVGATTFTRSANGRLFGGEAELAWQVADTLRFDASLGYLNSKYKGNVIDPANPASPTLNVNGNPFPNAPE
VTFQAGFDWDMIDDGTNKLTLRGDASYMGKYYFDPFKNYGQTPCDTPPAGSNITLAGKAITCANPGYWLANARLTYAHDN
MSVSLWAKNLFDKYYYTYGLNLNVFGYDYLNRGMPRTYGVEATVKF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 91852; Mature: 91721

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAHAQDAASQGEKPEAQEGDLETIVVTAQKREQNLQDVPAAVSAIGGETLRTRGITETS
CCCCCCHHHHCCCCCCCCCCCEEEEEEEECHHHCCHHHHHHHHHHCCCCCEEECCCCCHH
DLMGAIPSLQVTTPYGRTQPNFSLRGISVANEFSASTASPVGVYVDEVYQSFRASHGLQL
HHHHCCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
YDIDRVEVLRGPQGTLYGRNTTGGAISFFTRKPDLGEANGYLTAGYANYDTFTVQGAAEA
EECCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCC
TLVPDILGVRVAGTFAKGDGWQRNVLPGNERDLGTTDTIGGRISIRFRPDPDLDINLKLY
EECCHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEE
AAKDDPWGTAPYAGGQLAGGQDALGYSRYDPQPFLGGRLLRDNEVAVDRVGKNISKSKGI
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCE
ALNIKWDVSDQFSVTSITGYDTGDYINNPDDCDGGPADLCSIGLTSTSKNFNQDLRFSYS
EEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCEEEEEC
NDRLDIIAGLYYGRDKVKTVNYPDFFGALRPLLLGAGLPGSYNNAAIGTPDAIRYIPAFA
CCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
ANPALGPGDAGFCDAIEINPNGFLDARSLIALQTDIAINNTGNGGMGGSFSAGCAGAGAP
CCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
PFTPILGEQRFDVSRPSKAIYGDVTWKTTERLTVAVGARYTQDKVNYLNGSTFLYALDGT
CCCCCCCCCCCCCCCCCCEEEECEEEECCCEEEEEECCEECCCHHEEECCCEEEEEECCC
TPVVNLIPYSNPYNPNLAPLEQREKANRLTGRINVSYEFADDIMGYLQYSRGYRSGSFNG
CCEEEEEECCCCCCCCCCCHHHHHHHHHCEEEEEEEEEHHHHHHHHHHHHCCCCCCCCCC
LAYQGVNQVYYIQPEKVNAYEAGLKTRLFDRRVQLNLAGFYYEYSNHQVTQAVGATTFTR
EEECCCCEEEEECCCCCCHHHHCCHHHHCCCEEEEEEEEEEEEECCCEEEHHHCCEEEEE
SANGRLFGGEAELAWQVADTLRFDASLGYLNSKYKGNVIDPANPASPTLNVNGNPFPNAP
CCCCCEECCCCEEEEEEEHHEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
EVTFQAGFDWDMIDDGTNKLTLRGDASYMGKYYFDPFKNYGQTPCDTPPAGSNITLAGKA
CEEEECCCCCEEECCCCCEEEEECCHHHCCCEECCHHHHCCCCCCCCCCCCCEEEEECCE
ITCANPGYWLANARLTYAHDNMSVSLWAKNLFDKYYYTYGLNLNVFGYDYLNRGMPRTYG
EEECCCCEEEECCEEEEEECCCEEEEEHHHHHHCEEEEEECEEEEEEHHHHHCCCCCEEC
VEATVKF
CEEEEEC
>Mature Secondary Structure 
PAHAQDAASQGEKPEAQEGDLETIVVTAQKREQNLQDVPAAVSAIGGETLRTRGITETS
CCCCCHHHHCCCCCCCCCCCEEEEEEEECHHHCCHHHHHHHHHHCCCCCEEECCCCCHH
DLMGAIPSLQVTTPYGRTQPNFSLRGISVANEFSASTASPVGVYVDEVYQSFRASHGLQL
HHHHCCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
YDIDRVEVLRGPQGTLYGRNTTGGAISFFTRKPDLGEANGYLTAGYANYDTFTVQGAAEA
EECCCEEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCC
TLVPDILGVRVAGTFAKGDGWQRNVLPGNERDLGTTDTIGGRISIRFRPDPDLDINLKLY
EECCHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEE
AAKDDPWGTAPYAGGQLAGGQDALGYSRYDPQPFLGGRLLRDNEVAVDRVGKNISKSKGI
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCE
ALNIKWDVSDQFSVTSITGYDTGDYINNPDDCDGGPADLCSIGLTSTSKNFNQDLRFSYS
EEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCEEEEEC
NDRLDIIAGLYYGRDKVKTVNYPDFFGALRPLLLGAGLPGSYNNAAIGTPDAIRYIPAFA
CCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
ANPALGPGDAGFCDAIEINPNGFLDARSLIALQTDIAINNTGNGGMGGSFSAGCAGAGAP
CCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
PFTPILGEQRFDVSRPSKAIYGDVTWKTTERLTVAVGARYTQDKVNYLNGSTFLYALDGT
CCCCCCCCCCCCCCCCCCEEEECEEEECCCEEEEEECCEECCCHHEEECCCEEEEEECCC
TPVVNLIPYSNPYNPNLAPLEQREKANRLTGRINVSYEFADDIMGYLQYSRGYRSGSFNG
CCEEEEEECCCCCCCCCCCHHHHHHHHHCEEEEEEEEEHHHHHHHHHHHHCCCCCCCCCC
LAYQGVNQVYYIQPEKVNAYEAGLKTRLFDRRVQLNLAGFYYEYSNHQVTQAVGATTFTR
EEECCCCEEEEECCCCCCHHHHCCHHHHCCCEEEEEEEEEEEEECCCEEEHHHCCEEEEE
SANGRLFGGEAELAWQVADTLRFDASLGYLNSKYKGNVIDPANPASPTLNVNGNPFPNAP
CCCCCEECCCCEEEEEEEHHEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
EVTFQAGFDWDMIDDGTNKLTLRGDASYMGKYYFDPFKNYGQTPCDTPPAGSNITLAGKA
CEEEECCCCCEEECCCCCEEEEECCHHHCCCEECCHHHHCCCCCCCCCCCCCEEEEECCE
ITCANPGYWLANARLTYAHDNMSVSLWAKNLFDKYYYTYGLNLNVFGYDYLNRGMPRTYG
EEECCCCEEEECCEEEEEECCCEEEEEHHHHHHCEEEEEECEEEEEEHHHHHCCCCCEEC
VEATVKF
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]