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The map label for this gene is 85374902

Identifier: 85374902

GI number: 85374902

Start: 2104920

End: 2105843

Strand: Direct

Name: 85374902

Synonym: ELI_10375

Alternate gene names: NA

Gene position: 2104920-2105843 (Clockwise)

Preceding gene: 85374901

Following gene: 85374903

Centisome position: 68.96

GC content: 65.58

Gene sequence:

>924_bases
ATGGCGCCGCGCCCCGAACGCGGCACCTTCAAGTTCGACAAATATTTCCTCGTTATGGAAGCGCTGCGGGCGAGCGGCGA
GCCGATCACCGAACACGCGCCCGAGCCGATGCCGCGCCAATGGCTGGAGGCAGTGCATTGCCCGGAATATGTCGAGCAAG
TCTTCACCGCCAGCGTGCCCCGCGAAAAGGAGCGGCGGATCGGGTTTCCCGTCACCGCGCATATCGCCAGCCGTGTGCGC
CACACCAATGGCGGTACCTGGCTGGCAGCGCAGCTGGCGATGGAGCACGGCTATGCCGCCAACAGCGCGGCGGGAAGCCA
TCATGCGCTGTTCGATACCGGGGCGGGTTACTGCGTGTTCAACGATCTCGCCGTTGCCGCCAACCGCCTGATCGCCGAGG
GCGATGCGAAGCGCGTGCTGGTCGTCGATCTCGACGTCCACCAGGGCGATGGCACCGCCAGCCTCACCGCCTTGCGCGAC
GATATCGTCACCTTCTCCATGCATGCGGAAAAGAACTTCCCCGTCCGCAAGGCCCGCTCGAACCATGACGTGGCATTGCC
GGACGGGATGGAGGATGTGGCGTATCTGGAGACGCTGGCCGAGCACCTGCCTCGGCTGCTGGATGATGTCGCGCCCGATA
TCGTGCTCTACCAGGCCGGGGTCGATCCGCACGAGGACGACAAGCTCGGTCGCCTCAATCTCACCAGCGAAGGCCTGGAC
GAACGTGATCGTTTTGTCGTGCGTGAGGTGCGCCGGCGTGGTCTGCCCATCGCCAGCGCGCTTGGCGGTGGCTATGGCGA
GGACCAGCGCGAGGTCGGCGCGCGCCATGCCCGGTCGATGCTCGCCATGGCGGCGGAAAACCGCAAGCATCCACGGCCGC
AGACTGCTAGGGCGAGATCGCAATCGCAGGAGACAGCGTCATGA

Upstream 100 bases:

>100_bases
CCGCAGCGAGGACGAGATCTACGACGAGCTGGCGATGCTCGCCACGACCGAGATCGCGACGGAGTAAGCCCTGCTCCACG
TCGTCCACCACGCAGATTAC

Downstream 100 bases:

>100_bases
GCGAGCAAATGGAAACGGATTATTTGATCGTCGGCGCGGGTGCGGTCGGCCTCGCCTTTGCCGACAGCCTGATCGCGCTC
GATCCGGATTGCCATGTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAPRPERGTFKFDKYFLVMEALRASGEPITEHAPEPMPRQWLEAVHCPEYVEQVFTASVPREKERRIGFPVTAHIASRVR
HTNGGTWLAAQLAMEHGYAANSAAGSHHALFDTGAGYCVFNDLAVAANRLIAEGDAKRVLVVDLDVHQGDGTASLTALRD
DIVTFSMHAEKNFPVRKARSNHDVALPDGMEDVAYLETLAEHLPRLLDDVAPDIVLYQAGVDPHEDDKLGRLNLTSEGLD
ERDRFVVREVRRRGLPIASALGGGYGEDQREVGARHARSMLAMAAENRKHPRPQTARARSQSQETAS

Sequences:

>Translated_307_residues
MAPRPERGTFKFDKYFLVMEALRASGEPITEHAPEPMPRQWLEAVHCPEYVEQVFTASVPREKERRIGFPVTAHIASRVR
HTNGGTWLAAQLAMEHGYAANSAAGSHHALFDTGAGYCVFNDLAVAANRLIAEGDAKRVLVVDLDVHQGDGTASLTALRD
DIVTFSMHAEKNFPVRKARSNHDVALPDGMEDVAYLETLAEHLPRLLDDVAPDIVLYQAGVDPHEDDKLGRLNLTSEGLD
ERDRFVVREVRRRGLPIASALGGGYGEDQREVGARHARSMLAMAAENRKHPRPQTARARSQSQETAS
>Mature_306_residues
APRPERGTFKFDKYFLVMEALRASGEPITEHAPEPMPRQWLEAVHCPEYVEQVFTASVPREKERRIGFPVTAHIASRVRH
TNGGTWLAAQLAMEHGYAANSAAGSHHALFDTGAGYCVFNDLAVAANRLIAEGDAKRVLVVDLDVHQGDGTASLTALRDD
IVTFSMHAEKNFPVRKARSNHDVALPDGMEDVAYLETLAEHLPRLLDDVAPDIVLYQAGVDPHEDDKLGRLNLTSEGLDE
RDRFVVREVRRRGLPIASALGGGYGEDQREVGARHARSMLAMAAENRKHPRPQTARARSQSQETAS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=242, Percent_Identity=29.7520661157025, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI209862883, Length=192, Percent_Identity=34.375, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI13128862, Length=179, Percent_Identity=29.0502793296089, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13128860, Length=178, Percent_Identity=29.7752808988764, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI8923769, Length=224, Percent_Identity=27.2321428571429, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI293336691, Length=151, Percent_Identity=29.1390728476821, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI30795204, Length=155, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI17158039, Length=155, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI30795202, Length=155, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=274, Percent_Identity=29.1970802919708, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17561978, Length=178, Percent_Identity=31.4606741573034, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=178, Percent_Identity=30.8988764044944, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537347, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=179, Percent_Identity=29.0502793296089, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=178, Percent_Identity=31.4606741573034, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=179, Percent_Identity=29.0502793296089, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649807, Length=249, Percent_Identity=30.9236947791165, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24657891, Length=178, Percent_Identity=29.7752808988764, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24644244, Length=179, Percent_Identity=26.8156424581006, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360899, Length=224, Percent_Identity=27.2321428571429, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24642146, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24642142, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24642144, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33885; Mature: 33754

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRPERGTFKFDKYFLVMEALRASGEPITEHAPEPMPRQWLEAVHCPEYVEQVFTASVP
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCC
REKERRIGFPVTAHIASRVRHTNGGTWLAAQLAMEHGYAANSAAGSHHALFDTGAGYCVF
CHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEH
NDLAVAANRLIAEGDAKRVLVVDLDVHQGDGTASLTALRDDIVTFSMHAEKNFPVRKARS
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHEEEEEECCCCCCHHHCCC
NHDVALPDGMEDVAYLETLAEHLPRLLDDVAPDIVLYQAGVDPHEDDKLGRLNLTSEGLD
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCC
ERDRFVVREVRRRGLPIASALGGGYGEDQREVGARHARSMLAMAAENRKHPRPQTARARS
HHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QSQETAS
HHHHCCC
>Mature Secondary Structure 
APRPERGTFKFDKYFLVMEALRASGEPITEHAPEPMPRQWLEAVHCPEYVEQVFTASVP
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCC
REKERRIGFPVTAHIASRVRHTNGGTWLAAQLAMEHGYAANSAAGSHHALFDTGAGYCVF
CHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEH
NDLAVAANRLIAEGDAKRVLVVDLDVHQGDGTASLTALRDDIVTFSMHAEKNFPVRKARS
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHEEEEEECCCCCCHHHCCC
NHDVALPDGMEDVAYLETLAEHLPRLLDDVAPDIVLYQAGVDPHEDDKLGRLNLTSEGLD
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCC
ERDRFVVREVRRRGLPIASALGGGYGEDQREVGARHARSMLAMAAENRKHPRPQTARARS
HHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QSQETAS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]