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The map label for this gene is yghA [C]

Identifier: 85374896

GI number: 85374896

Start: 2099894

End: 2100868

Strand: Direct

Name: yghA [C]

Synonym: ELI_10345

Alternate gene names: 85374896

Gene position: 2099894-2100868 (Clockwise)

Preceding gene: 85374895

Following gene: 85374897

Centisome position: 68.79

GC content: 61.85

Gene sequence:

>975_bases
ATGAGCGAATTCGGTTTCAAGAGTACTGCCGACGACGTGCTGGCTGACAAGGACCTGAGCGGGAAGACCGCCTTCATCAC
CGGCGGCTATTCCGGCCTCGGGCAGGAAACAGCACGCGCGATGGCGGCCAAGGGTGCCCATGTCATCATCGCCGGGCGCG
ATATGGAAAAAGCCAACGCCGCCGCAGAGGAAATTCGCGGGCAGGTAGAGGGCGCGCAGGTGGATACCATCCAATGCGAT
CTCGCCTCGCTGGATTCCGTCCGGGCGTGCGGCGCCGAAGCACGCGAGCGGTTCGACAGCATCGACCTGCTGATCAACAA
TGCCGGGGTCATGGCCTGTCCGCAAAACGAGACCGCCGATGGTTTCGAAATGCAGTTCGGCACCAACCATCTCGGCCATT
TCCTGCTGACCAAAGAACTGATGCCGCTCGTGGAAAAGGGCGCGGGCGAAGGCGATGGCGCGCGCATCGTCAACCTTTCC
AGCCGCGGCCACCACATCGACGACGTCCATCTGGACGACCCGAATTTCGAGAATCGCGAATACCAGAAATGGGCGAGCTA
CGGCCAGTCGAAGACCGCCAATATCCTGTTCAGCGTCGGGCTGGAGAACCGCTTCGGACATAAGGGGATCACGTCGATCG
CGGTCCATCCAGGCGGGATCCAGACCAATCTGGGCCGGCATATGACCGACGAAGACAGGGTCTGGATGCGCAAGCGGATG
AAGGCGGACAGCGACGAGGAGATGGCCAAGGCGTTCAAGTCGATCCCGCAAGGCGCCGCCACCACCTGCTATGCCGCGAC
GGAACAGAGCCTGCAGGGCCACGGCGGGGTCTATTGCGAGGATTGTCACGTTGCCGAGGTCGATGACGAAAGCAGCGACG
GCGGTGTGAGAAGCTATGCCGTCGATCCTGCCCGCGCTGATGCGCTGTGGGCGCTATCCGAAAAGATGGTCGGCGAAAGC
TTCGACAACCCCTGA

Upstream 100 bases:

>100_bases
ATTTCTACGTCGGAGAACATCGGGACGAAGAATTCCTGTACGAACTACGATTGGGTCGAGCGCGTCGCCCCCGGCGGCCC
GCCAAGAGGGAGAGACGACC

Downstream 100 bases:

>100_bases
TGGCTAGGCGCTGACGAAAAATTCTGCCGCCATGTAACCGCCGGAGCCCTGGCCGCGAAAAGCCGTGCGACACCTGCCAA
GGGGAGCGAAGCAGATGATT

Product: oxidoreductase, short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSEFGFKSTADDVLADKDLSGKTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANAAAEEIRGQVEGAQVDTIQCD
LASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETADGFEMQFGTNHLGHFLLTKELMPLVEKGAGEGDGARIVNLS
SRGHHIDDVHLDDPNFENREYQKWASYGQSKTANILFSVGLENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRM
KADSDEEMAKAFKSIPQGAATTCYAATEQSLQGHGGVYCEDCHVAEVDDESSDGGVRSYAVDPARADALWALSEKMVGES
FDNP

Sequences:

>Translated_324_residues
MSEFGFKSTADDVLADKDLSGKTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANAAAEEIRGQVEGAQVDTIQCD
LASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETADGFEMQFGTNHLGHFLLTKELMPLVEKGAGEGDGARIVNLS
SRGHHIDDVHLDDPNFENREYQKWASYGQSKTANILFSVGLENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRM
KADSDEEMAKAFKSIPQGAATTCYAATEQSLQGHGGVYCEDCHVAEVDDESSDGGVRSYAVDPARADALWALSEKMVGES
FDNP
>Mature_323_residues
SEFGFKSTADDVLADKDLSGKTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANAAAEEIRGQVEGAQVDTIQCDL
ASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETADGFEMQFGTNHLGHFLLTKELMPLVEKGAGEGDGARIVNLSS
RGHHIDDVHLDDPNFENREYQKWASYGQSKTANILFSVGLENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRMK
ADSDEEMAKAFKSIPQGAATTCYAATEQSLQGHGGVYCEDCHVAEVDDESSDGGVRSYAVDPARADALWALSEKMVGESF
DNP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=304, Percent_Identity=38.8157894736842, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI186928839, Length=305, Percent_Identity=37.0491803278689, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI166795268, Length=306, Percent_Identity=36.2745098039216, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI10190746, Length=313, Percent_Identity=38.0191693290735, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI7706523, Length=321, Percent_Identity=34.8909657320872, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI193804850, Length=262, Percent_Identity=35.8778625954198, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI19923931, Length=268, Percent_Identity=38.4328358208955, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI146231950, Length=306, Percent_Identity=32.6797385620915, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI7705421, Length=235, Percent_Identity=29.3617021276596, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=211, Percent_Identity=29.8578199052133, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787335, Length=272, Percent_Identity=26.8382352941176, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=102, Percent_Identity=38.2352941176471, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=243, Percent_Identity=27.1604938271605, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532805, Length=336, Percent_Identity=35.4166666666667, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI193207620, Length=339, Percent_Identity=34.5132743362832, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17532791, Length=329, Percent_Identity=32.8267477203647, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71992402, Length=324, Percent_Identity=31.4814814814815, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17558006, Length=280, Percent_Identity=32.5, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32565532, Length=229, Percent_Identity=36.2445414847162, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17535059, Length=325, Percent_Identity=31.6923076923077, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI72001364, Length=220, Percent_Identity=35.4545454545455, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=313, Percent_Identity=25.5591054313099, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115533174, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115533172, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=240, Percent_Identity=31.6666666666667, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19921754, Length=301, Percent_Identity=35.8803986710963, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24586328, Length=297, Percent_Identity=36.3636363636364, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129347, Length=324, Percent_Identity=33.9506172839506, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI28573296, Length=299, Percent_Identity=38.1270903010033, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI22024069, Length=303, Percent_Identity=35.3135313531353, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI161076371, Length=299, Percent_Identity=36.4548494983278, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI45554248, Length=297, Percent_Identity=35.016835016835, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24640117, Length=297, Percent_Identity=35.016835016835, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24647946, Length=322, Percent_Identity=31.6770186335404, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45553409, Length=307, Percent_Identity=32.2475570032573, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24647948, Length=307, Percent_Identity=32.2475570032573, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24656154, Length=310, Percent_Identity=31.9354838709677, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922628, Length=310, Percent_Identity=31.9354838709677, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24647931, Length=295, Percent_Identity=27.7966101694915, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=27.843137254902, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=225, Percent_Identity=27.5555555555556, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=210, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357041, Length=208, Percent_Identity=27.8846153846154, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34925; Mature: 34794

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFGFKSTADDVLADKDLSGKTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANA
CCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHH
AAEEIRGQVEGAQVDTIQCDLASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETAD
HHHHHHHHCCCCEEEEEEECHHHHHHHHHCCHHHHHHHCCEEEEEECCCEEECCCCCCCC
GFEMQFGTNHLGHFLLTKELMPLVEKGAGEGDGARIVNLSSRGHHIDDVHLDDPNFENRE
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCHH
YQKWASYGQSKTANILFSVGLENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRM
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
KADSDEEMAKAFKSIPQGAATTCYAATEQSLQGHGGVYCEDCHVAEVDDESSDGGVRSYA
CCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCEEEEE
VDPARADALWALSEKMVGESFDNP
CCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEFGFKSTADDVLADKDLSGKTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANA
CCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHH
AAEEIRGQVEGAQVDTIQCDLASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETAD
HHHHHHHHCCCCEEEEEEECHHHHHHHHHCCHHHHHHHCCEEEEEECCCEEECCCCCCCC
GFEMQFGTNHLGHFLLTKELMPLVEKGAGEGDGARIVNLSSRGHHIDDVHLDDPNFENRE
CEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCCCHH
YQKWASYGQSKTANILFSVGLENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRM
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
KADSDEEMAKAFKSIPQGAATTCYAATEQSLQGHGGVYCEDCHVAEVDDESSDGGVRSYA
CCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCEEEEE
VDPARADALWALSEKMVGESFDNP
CCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]