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The map label for this gene is caiD [C]

Identifier: 85374856

GI number: 85374856

Start: 2061405

End: 2062217

Strand: Reverse

Name: caiD [C]

Synonym: ELI_10145

Alternate gene names: 85374856

Gene position: 2062217-2061405 (Counterclockwise)

Preceding gene: 85374857

Following gene: 85374854

Centisome position: 67.56

GC content: 64.08

Gene sequence:

>813_bases
ATGGAATTCCCCACCAACGATCGCGTGTCGATCACGCTGGAAGACGATGGCGTCGCGCAGGTCCGCTTCGTGCGCGCGGA
TAAAATGAACGCGCTCGACCATGAGATGTTCGAGACGATGATCGCCGCTGCCGAGGCACTGCAGGCCGAACCCCGGGTGC
GGGCGGTCGTCCTTTCGGGGGAAGGGAAGGCCTTCTGTGCCGGCCTCGACCTGTCCAATTTCAGCAATCCCACCGGCTCG
GGCAGCGGCAAGCTGGCGGACCGGACGCACGGCGATTCCAACCGCGCGCAGCAGGTCGCGACACAATGGCGCAAGCTCAA
GGTGCCGGTGATCGCTGCCGTTCACGGCGTGTGCTTCGGCGGCGGGCTGCAGATCGCCAGCGGCGCCGATATCCGTGTCG
TTCATCCGGCGACGCGCATGGCGATCATGGAGATGAAGTGGGGGCTGGTCCCCGACATGGGCGGCTACGTGCTGTGGCGC
GGCCTGGTTCGCGATGATGTATTGCGCGAGCTGATCTTCACCAATCGGGAATTCACCGGTGCCGAAGCGCAGGCACTCGG
CCTCGCAACCCATGTCGATGAGGATCCGCACGCCAGAGCGACCGAGCTCGCTCGCGTGATCGCCGATCGCAATCCGCACG
CCATGCAGGCGTCCAAGCGCATCGCCAACAAGATGTACGACATGACCGGCTCCGAACTGCTCATCGAAGAGAGCGTCGAG
CAGGATCAGATCATTCGTCAGCCCAACCAGGTCGAGGCTGTGATGGCCGGCATGCAGAAGCGCAAGGCAGCCTACGCCGA
CGTCGAAGGATAG

Upstream 100 bases:

>100_bases
TGAGGAGGGTCGCACCTGTCCAGCCCCGACCTTTGACGGGGCTGGACAGGCCTCTTTCAATCGGCGACGATCCTGCCAAC
GATTTTGCAGGAGTCAAAGG

Downstream 100 bases:

>100_bases
GTCGCGCCGCCGTCAGCCGAAGACGGCAACGGATTGCAATCCGTCCATCACCTGCACGCCGTCGGCATTCCAGAGCCGTA
GCCGCTCGCTCGAATAGCCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MEFPTNDRVSITLEDDGVAQVRFVRADKMNALDHEMFETMIAAAEALQAEPRVRAVVLSGEGKAFCAGLDLSNFSNPTGS
GSGKLADRTHGDSNRAQQVATQWRKLKVPVIAAVHGVCFGGGLQIASGADIRVVHPATRMAIMEMKWGLVPDMGGYVLWR
GLVRDDVLRELIFTNREFTGAEAQALGLATHVDEDPHARATELARVIADRNPHAMQASKRIANKMYDMTGSELLIEESVE
QDQIIRQPNQVEAVMAGMQKRKAAYADVEG

Sequences:

>Translated_270_residues
MEFPTNDRVSITLEDDGVAQVRFVRADKMNALDHEMFETMIAAAEALQAEPRVRAVVLSGEGKAFCAGLDLSNFSNPTGS
GSGKLADRTHGDSNRAQQVATQWRKLKVPVIAAVHGVCFGGGLQIASGADIRVVHPATRMAIMEMKWGLVPDMGGYVLWR
GLVRDDVLRELIFTNREFTGAEAQALGLATHVDEDPHARATELARVIADRNPHAMQASKRIANKMYDMTGSELLIEESVE
QDQIIRQPNQVEAVMAGMQKRKAAYADVEG
>Mature_270_residues
MEFPTNDRVSITLEDDGVAQVRFVRADKMNALDHEMFETMIAAAEALQAEPRVRAVVLSGEGKAFCAGLDLSNFSNPTGS
GSGKLADRTHGDSNRAQQVATQWRKLKVPVIAAVHGVCFGGGLQIASGADIRVVHPATRMAIMEMKWGLVPDMGGYVLWR
GLVRDDVLRELIFTNREFTGAEAQALGLATHVDEDPHARATELARVIADRNPHAMQASKRIANKMYDMTGSELLIEESVE
QDQIIRQPNQVEAVMAGMQKRKAAYADVEG

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=224, Percent_Identity=30.3571428571429, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4502327, Length=277, Percent_Identity=29.9638989169675, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=25.78125, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI68989263, Length=251, Percent_Identity=26.6932270916335, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI221142681, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=213, Percent_Identity=29.1079812206573, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787659, Length=234, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=275, Percent_Identity=28.7272727272727, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17540714, Length=256, Percent_Identity=30.078125, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=221, Percent_Identity=28.5067873303167, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=201, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=190, Percent_Identity=32.1052631578947, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=190, Percent_Identity=32.1052631578947, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=228, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=29.3436293436293, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920382, Length=219, Percent_Identity=30.1369863013699, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650670, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129971, Length=263, Percent_Identity=25.0950570342205, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24653477, Length=263, Percent_Identity=25.0950570342205, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29485; Mature: 29485

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFPTNDRVSITLEDDGVAQVRFVRADKMNALDHEMFETMIAAAEALQAEPRVRAVVLSG
CCCCCCCEEEEEECCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
EGKAFCAGLDLSNFSNPTGSGSGKLADRTHGDSNRAQQVATQWRKLKVPVIAAVHGVCFG
CCCEEEEECCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
GGLQIASGADIRVVHPATRMAIMEMKWGLVPDMGGYVLWRGLVRDDVLRELIFTNREFTG
CCEEEECCCCEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
AEAQALGLATHVDEDPHARATELARVIADRNPHAMQASKRIANKMYDMTGSELLIEESVE
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCC
QDQIIRQPNQVEAVMAGMQKRKAAYADVEG
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEFPTNDRVSITLEDDGVAQVRFVRADKMNALDHEMFETMIAAAEALQAEPRVRAVVLSG
CCCCCCCEEEEEECCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
EGKAFCAGLDLSNFSNPTGSGSGKLADRTHGDSNRAQQVATQWRKLKVPVIAAVHGVCFG
CCCEEEEECCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
GGLQIASGADIRVVHPATRMAIMEMKWGLVPDMGGYVLWRGLVRDDVLRELIFTNREFTG
CCEEEECCCCEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
AEAQALGLATHVDEDPHARATELARVIADRNPHAMQASKRIANKMYDMTGSELLIEESVE
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCC
QDQIIRQPNQVEAVMAGMQKRKAAYADVEG
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA