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The map label for this gene is yajO [H]

Identifier: 85374848

GI number: 85374848

Start: 2051972

End: 2052994

Strand: Direct

Name: yajO [H]

Synonym: ELI_10105

Alternate gene names: 85374848

Gene position: 2051972-2052994 (Clockwise)

Preceding gene: 85374838

Following gene: 85374855

Centisome position: 67.22

GC content: 63.05

Gene sequence:

>1023_bases
ATGCAATACGCCCAGTTCGGCAATACCGGCCTCACCGTTTCGCGGCTGTGCCTTGGGTGTATGAGCTTCGGCGATGCGGC
GGCCGAAGGCCACGACTGGACGCTGAGCGAAGAAGAATCGCGCCCGTTCTTTCGCCAGGCGCTGGAAGCGGGCATCAACT
TCTTCGATACCGCCAATGCCTATTCGGGCGGGACAAGCGAAGAGATTACCGGCAAGCTCCTCACCGAAATGGCGCGGCGC
GACGAGGTCGTGATTGCCACCAAGGGTTTCTTCCGTTGGCGGCAAGCGCCCAATGCCGGCGGCCTGTCGGCCAAGGCGCT
GATCCACGCGGTCGACGACAGCCTGCGCCGGCTCGGCACCGATTACATCGACCTTTACCAGATCCACCGGCTCGACCCGC
TGACCCCGATGGAAGAGATCGTCGAGACGCTCGACATGATCGTGCGCAGCGGCAAGGTGCGCTATGTCGGCGCGTCCAGC
ATGAATGCCTGGCAATTCCAGAAGATGCTCCACATCGCCGAGCGCGGCGGGTTCAAGAAATTCGTCTCGATGCAGAATTA
CGTGAACCTGCTCTATCGCGAGGAAGAGCGCGAAATGCTGCCGCTGTGCCGCGATGCGGGGATCGCGGTGACGCCGTGGA
GTCCGCTCGCGCGCGGCAAGCTAACGCGGCCCGCTAGCGAAGGCGGAACCAAGCGGGCGGAGACCGACCGCTTGATCCCG
GCTCTCTATTCGCGGACCGAGGACGCTGACAATGAGGTCATCGGCGCGGTCGAGGCCATCGCCAAGGCGCGCGGCGTGCC
GATGGCGCAGGTTGCGCTGGCGTGGGTGCTGCAGAAGCCGGGCGTGACCAGTCCGATCGTCGGTGCGACCAAGCCAAAGC
ATATCGAAGATGCCGTGGCTGCGGTCGAATTGCAGTTGAGCGAGGAGGAAATCAGGCAGCTCGAAGCGCCCTATGTCCCA
CATCCCGTTATGGGTATGTTCGACATGCCGGTACCGGAATTGAAGGTATCGGTTCGCGGCTGA

Upstream 100 bases:

>100_bases
CCCACATATAAAGACATCGTTATATCGGCAAGTGAGTTTCTCTGCTTACGCCCAAAGCGAAGCAATGTTACGCGCCGGCG
CAGATCGAGGAGAGAAAAGC

Downstream 100 bases:

>100_bases
TGGACCTCAGTCGCACGGCGCGACAGTAAGGTCCTCGACCACGACCGAGCCTTGCTCCTCGACGGTAATTTCGTAGTCCT
GCGCGAAGCAAATCCCCAGC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQYAQFGNTGLTVSRLCLGCMSFGDAAAEGHDWTLSEEESRPFFRQALEAGINFFDTANAYSGGTSEEITGKLLTEMARR
DEVVIATKGFFRWRQAPNAGGLSAKALIHAVDDSLRRLGTDYIDLYQIHRLDPLTPMEEIVETLDMIVRSGKVRYVGASS
MNAWQFQKMLHIAERGGFKKFVSMQNYVNLLYREEEREMLPLCRDAGIAVTPWSPLARGKLTRPASEGGTKRAETDRLIP
ALYSRTEDADNEVIGAVEAIAKARGVPMAQVALAWVLQKPGVTSPIVGATKPKHIEDAVAAVELQLSEEEIRQLEAPYVP
HPVMGMFDMPVPELKVSVRG

Sequences:

>Translated_340_residues
MQYAQFGNTGLTVSRLCLGCMSFGDAAAEGHDWTLSEEESRPFFRQALEAGINFFDTANAYSGGTSEEITGKLLTEMARR
DEVVIATKGFFRWRQAPNAGGLSAKALIHAVDDSLRRLGTDYIDLYQIHRLDPLTPMEEIVETLDMIVRSGKVRYVGASS
MNAWQFQKMLHIAERGGFKKFVSMQNYVNLLYREEEREMLPLCRDAGIAVTPWSPLARGKLTRPASEGGTKRAETDRLIP
ALYSRTEDADNEVIGAVEAIAKARGVPMAQVALAWVLQKPGVTSPIVGATKPKHIEDAVAAVELQLSEEEIRQLEAPYVP
HPVMGMFDMPVPELKVSVRG
>Mature_340_residues
MQYAQFGNTGLTVSRLCLGCMSFGDAAAEGHDWTLSEEESRPFFRQALEAGINFFDTANAYSGGTSEEITGKLLTEMARR
DEVVIATKGFFRWRQAPNAGGLSAKALIHAVDDSLRRLGTDYIDLYQIHRLDPLTPMEEIVETLDMIVRSGKVRYVGASS
MNAWQFQKMLHIAERGGFKKFVSMQNYVNLLYREEEREMLPLCRDAGIAVTPWSPLARGKLTRPASEGGTKRAETDRLIP
ALYSRTEDADNEVIGAVEAIAKARGVPMAQVALAWVLQKPGVTSPIVGATKPKHIEDAVAAVELQLSEEEIRQLEAPYVP
HPVMGMFDMPVPELKVSVRG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=30.1282051282051, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI27436962, Length=315, Percent_Identity=29.5238095238095, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=28.7878787878788, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=28.6585365853659, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=29.8076923076923, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=29.7872340425532, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI223718702, Length=282, Percent_Identity=27.3049645390071, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=27.4725274725275, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI41152114, Length=180, Percent_Identity=31.6666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=51.5337423312883, Blast_Score=351, Evalue=4e-98,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789199, Length=360, Percent_Identity=28.3333333333333, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=31.2121212121212, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=30.1694915254237, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI48994888, Length=293, Percent_Identity=26.2798634812287, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=304, Percent_Identity=24.6710526315789, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17566692, Length=302, Percent_Identity=24.1721854304636, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=40.2366863905325, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=32.1321321321321, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=317, Percent_Identity=30.9148264984227, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6319951, Length=335, Percent_Identity=31.044776119403, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322615, Length=264, Percent_Identity=31.0606060606061, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6321052, Length=152, Percent_Identity=36.1842105263158, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640980, Length=368, Percent_Identity=25.2717391304348, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=360, Percent_Identity=25.2777777777778, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24646155, Length=344, Percent_Identity=26.453488372093, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646159, Length=181, Percent_Identity=32.0441988950276, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644950, Length=310, Percent_Identity=24.8387096774194, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37590; Mature: 37590

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYAQFGNTGLTVSRLCLGCMSFGDAAAEGHDWTLSEEESRPFFRQALEAGINFFDTANA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YSGGTSEEITGKLLTEMARRDEVVIATKGFFRWRQAPNAGGLSAKALIHAVDDSLRRLGT
CCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
DYIDLYQIHRLDPLTPMEEIVETLDMIVRSGKVRYVGASSMNAWQFQKMLHIAERGGFKK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCHHH
FVSMQNYVNLLYREEEREMLPLCRDAGIAVTPWSPLARGKLTRPASEGGTKRAETDRLIP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHH
ALYSRTEDADNEVIGAVEAIAKARGVPMAQVALAWVLQKPGVTSPIVGATKPKHIEDAVA
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
AVELQLSEEEIRQLEAPYVPHPVMGMFDMPVPELKVSVRG
HHHEECCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MQYAQFGNTGLTVSRLCLGCMSFGDAAAEGHDWTLSEEESRPFFRQALEAGINFFDTANA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
YSGGTSEEITGKLLTEMARRDEVVIATKGFFRWRQAPNAGGLSAKALIHAVDDSLRRLGT
CCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
DYIDLYQIHRLDPLTPMEEIVETLDMIVRSGKVRYVGASSMNAWQFQKMLHIAERGGFKK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCHHH
FVSMQNYVNLLYREEEREMLPLCRDAGIAVTPWSPLARGKLTRPASEGGTKRAETDRLIP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHH
ALYSRTEDADNEVIGAVEAIAKARGVPMAQVALAWVLQKPGVTSPIVGATKPKHIEDAVA
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
AVELQLSEEEIRQLEAPYVPHPVMGMFDMPVPELKVSVRG
HHHEECCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]