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The map label for this gene is phr [H]

Identifier: 85374772

GI number: 85374772

Start: 1976713

End: 1977936

Strand: Direct

Name: phr [H]

Synonym: ELI_09725

Alternate gene names: 85374772

Gene position: 1976713-1977936 (Clockwise)

Preceding gene: 85374765

Following gene: 85374773

Centisome position: 64.76

GC content: 64.22

Gene sequence:

>1224_bases
ATGCCCTTCACGCCCACACGCTCTGCCGGTTTCGACCGGCTTCAAGCTTTCCTGCCTGATGCCGGGCGACAATATGCGGA
GACGCGCAATTACGATGACGGGCCCGGGCGCGGCAATGTGTCGCAGCTTTCCCCGTGGCTCCATACCGGGCTGCTGCGCG
AACATGAGGTGCTGGAAGCGACGTTGCGCGAGCACGGCGCAAGGGCCGCCGAAAAGTTCGGCAACGAAATCTTTTGGCGG
GTCTATTTCAAAGGCTATCTCGAACAGCGCCCGAGTATCTGGCGCAGCTATTGCCAGCAGCGCGATACGGCCTTGACCGC
CCTTGACCGCAATGCCGGCGACCGCACCGCATACGAAGAGGCGACCGAAGGCCGAACCGGGATCGGGGCGTTCGACTACT
GGGCACAGGAGCTGATCGAGACTGGCTATCTCCACAACCACGCCCGTATGTGGTTTGCCAGCATCTGGATCTTTACGCTT
AAGCTCGACTGGACGCTCGGCGCGGATTTTTTCCTGCGACATCTGGTGGACGGCGACGCGGCCTCGAACACGTTGAGCTG
GCGCTGGGTCGGCGGGCTTCACACCAAGGGCAAGACCTATCTCGCCACCAAAGACAATATCGCGCGCTATATCGGCCGTC
ATCCCGACGGGCCTCTCGATGCCGAAGGATTGGCGACCGATGCGTCGGCGCTGACCGAGCCCGAAGATCATGGGCGGCAG
GCGCCGGACCTTCCCGGCCCGGCCGGCTCCGAATCTTACGCGGAACCCTATGCCCTGTTGCTGCATGACGAAGCTGCCAG
CCACGTGCCGCTCGACCTACCCAAGCCTCCTGCGCTGGTCATTGGCGCAGCGCGGCCAGGTGCGCGCAGTCCTTTGCCGA
CCGCCAAACCGCTGCGCTCGTTCGCGCGGGATGCGGTCGCAAACGGCACCGAAGCGGCCAGAAAAGCATGGTCCTGTCCG
CACGCAGAGTGGAGCCCCCAGACGCCCCTTTCCGACCTGCTAACTCCCCACGGTATCGATCTCGTCGTCACGCCCTTCCT
GCCCACCGGTTGGACCCGCGATGCGCTCTGGCCCGCCCTTGCACCGCTGGCCGAGGAAGGTCGGCTTGTTCAGGTCCTGC
CCGATCTCCAGCGCGCAACCTGGCCGCATGCGACGGCCGGGTTCTTCGGGGTGAAGAAGAAGATCGAAACTGCGATGCGT
GAGGCCAGGATTGTCGGGGCCTGA

Upstream 100 bases:

>100_bases
GCTCGTAATGTCTCCTCCGTTTGGACCCAGCCTAGCGGCGGTCGACCCCGCAGCACAAGCGCGGGAGGAACCTGTGCTGG
CGCCCGTCGGTTGTGCCGAC

Downstream 100 bases:

>100_bases
GCGCCTGCCGGTACTCATCCCGTAATGCATGGCGCACCGCCGCTCTTGAAGCCAATCTCCCCCGAACCATCGGAACCTCA
TCCGCGATTTCTCGTTTTGG

Product: DNA photolyase-like protein

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPFTPTRSAGFDRLQAFLPDAGRQYAETRNYDDGPGRGNVSQLSPWLHTGLLREHEVLEATLREHGARAAEKFGNEIFWR
VYFKGYLEQRPSIWRSYCQQRDTALTALDRNAGDRTAYEEATEGRTGIGAFDYWAQELIETGYLHNHARMWFASIWIFTL
KLDWTLGADFFLRHLVDGDAASNTLSWRWVGGLHTKGKTYLATKDNIARYIGRHPDGPLDAEGLATDASALTEPEDHGRQ
APDLPGPAGSESYAEPYALLLHDEAASHVPLDLPKPPALVIGAARPGARSPLPTAKPLRSFARDAVANGTEAARKAWSCP
HAEWSPQTPLSDLLTPHGIDLVVTPFLPTGWTRDALWPALAPLAEEGRLVQVLPDLQRATWPHATAGFFGVKKKIETAMR
EARIVGA

Sequences:

>Translated_407_residues
MPFTPTRSAGFDRLQAFLPDAGRQYAETRNYDDGPGRGNVSQLSPWLHTGLLREHEVLEATLREHGARAAEKFGNEIFWR
VYFKGYLEQRPSIWRSYCQQRDTALTALDRNAGDRTAYEEATEGRTGIGAFDYWAQELIETGYLHNHARMWFASIWIFTL
KLDWTLGADFFLRHLVDGDAASNTLSWRWVGGLHTKGKTYLATKDNIARYIGRHPDGPLDAEGLATDASALTEPEDHGRQ
APDLPGPAGSESYAEPYALLLHDEAASHVPLDLPKPPALVIGAARPGARSPLPTAKPLRSFARDAVANGTEAARKAWSCP
HAEWSPQTPLSDLLTPHGIDLVVTPFLPTGWTRDALWPALAPLAEEGRLVQVLPDLQRATWPHATAGFFGVKKKIETAMR
EARIVGA
>Mature_406_residues
PFTPTRSAGFDRLQAFLPDAGRQYAETRNYDDGPGRGNVSQLSPWLHTGLLREHEVLEATLREHGARAAEKFGNEIFWRV
YFKGYLEQRPSIWRSYCQQRDTALTALDRNAGDRTAYEEATEGRTGIGAFDYWAQELIETGYLHNHARMWFASIWIFTLK
LDWTLGADFFLRHLVDGDAASNTLSWRWVGGLHTKGKTYLATKDNIARYIGRHPDGPLDAEGLATDASALTEPEDHGRQA
PDLPGPAGSESYAEPYALLLHDEAASHVPLDLPKPPALVIGAARPGARSPLPTAKPLRSFARDAVANGTEAARKAWSCPH
AEWSPQTPLSDLLTPHGIDLVVTPFLPTGWTRDALWPALAPLAEEGRLVQVLPDLQRATWPHATAGFFGVKKKIETAMRE
ARIVGA

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=207, Percent_Identity=28.0193236714976, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324962, Length=192, Percent_Identity=27.0833333333333, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 45044; Mature: 44913

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTPTRSAGFDRLQAFLPDAGRQYAETRNYDDGPGRGNVSQLSPWLHTGLLREHEVLEA
CCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLREHGARAAEKFGNEIFWRVYFKGYLEQRPSIWRSYCQQRDTALTALDRNAGDRTAYEE
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ATEGRTGIGAFDYWAQELIETGYLHNHARMWFASIWIFTLKLDWTLGADFFLRHLVDGDA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCC
ASNTLSWRWVGGLHTKGKTYLATKDNIARYIGRHPDGPLDAEGLATDASALTEPEDHGRQ
CCCCEEEEEECCCCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHCCC
APDLPGPAGSESYAEPYALLLHDEAASHVPLDLPKPPALVIGAARPGARSPLPTAKPLRS
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
FARDAVANGTEAARKAWSCPHAEWSPQTPLSDLLTPHGIDLVVTPFLPTGWTRDALWPAL
HHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEECCCCCCCCHHHHHHHH
APLAEEGRLVQVLPDLQRATWPHATAGFFGVKKKIETAMREARIVGA
HHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFTPTRSAGFDRLQAFLPDAGRQYAETRNYDDGPGRGNVSQLSPWLHTGLLREHEVLEA
CCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TLREHGARAAEKFGNEIFWRVYFKGYLEQRPSIWRSYCQQRDTALTALDRNAGDRTAYEE
HHHHHHHHHHHHHCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ATEGRTGIGAFDYWAQELIETGYLHNHARMWFASIWIFTLKLDWTLGADFFLRHLVDGDA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCC
ASNTLSWRWVGGLHTKGKTYLATKDNIARYIGRHPDGPLDAEGLATDASALTEPEDHGRQ
CCCCEEEEEECCCCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHCCC
APDLPGPAGSESYAEPYALLLHDEAASHVPLDLPKPPALVIGAARPGARSPLPTAKPLRS
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
FARDAVANGTEAARKAWSCPHAEWSPQTPLSDLLTPHGIDLVVTPFLPTGWTRDALWPAL
HHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEECCCCCCCCHHHHHHHH
APLAEEGRLVQVLPDLQRATWPHATAGFFGVKKKIETAMREARIVGA
HHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2501760 [H]