Click here to switch to the map view.

The map label for this gene is sdcS [H]

Identifier: 85374718

GI number: 85374718

Start: 1933688

End: 1935097

Strand: Direct

Name: sdcS [H]

Synonym: ELI_09455

Alternate gene names: 85374718

Gene position: 1933688-1935097 (Clockwise)

Preceding gene: 85374717

Following gene: 85374719

Centisome position: 63.35

GC content: 66.31

Gene sequence:

>1410_bases
ATGACTGCACAACGGATCGGATTTGTCATCGGCCTCGTCGGGCTGCTGACCGGCACCTTTGCGCCGACGCCGGAAGGCAT
GAGCCGCGAAGCATTCATCGTCGCCGGGCTGGTCGTGCTGATGGCGAGCTGGTGGATGACGGAGGCGCTGCCGCTGACCG
CGACCGCGCTGATGCCGTTCCTGGTCCTGCCTTTTGCCGGTGTCTCGAATGCGCGCGACACGGCGGCGACCTATTATTCC
CCGATCCTGTTCCTGCTGCTCGGCGGCGCCTTCATTGCGCTCGCCATCGAGCGAACCGGGCTGCACAAGCGCCTGAGCCT
GGCAATCCTGCGCACGGTCGGTTCGAGCGGTGGACAGGCGCGGCTGCTCCTCGCCTTCATGATCAGCGCGGCACTGCTCT
CGATGCTGATCTCGAACACTTCGACCAGCCTGATCATGATGCCGATGGCGCTGGCCGTGCTAGCTGGCGGAGGCATCGCC
GCCGACGAGCGTGAGGGGCTGGCAGGTGCCCTGCCCATGGGGATCGCATTTGCTGCCAGTATCGGCGGGCTCGGCACGCT
GGTCGGCTCGCCCACGAATGCCATTGCCGTCGGCCTGCTCGACCAGACGATCGGCGTGCAGATCACCTTTGCCGAGTGGA
CGCTCTACGGTCTTCCCGTGGTCATATGCGGCGTACCGATAGCCGCACTCATCATCTCGCGGTTCCAACAGGTTGCAGCG
CATCCTTTCGATGTCGCAGGTGCCCGCGACGCCATCCGTGTGGGCGCCCAATGGTCGACTGCCGAACGACGGCTGGTGCC
GGTCGTGGCGCTGACATTCCTGCTGTGGATGACGCGCCCGCTGCTCGCCGATTATCTTCCCGCAGGATCGCTGACCGACG
GCACCATCGCCATCGCTGCCAGCCTCGCGCTATTCCTGCTGCCCGATGGCACAGGCCGCCCGCTGCTCGTCTGGAAGGAA
GCCGACCGCGCACCGTGGGGCGTCATCATGATGTTCGGCGGTGGACTGGCGCTGGCTGCGGGCATGAGCGCGAGCGGGCT
CGCCGAATGGCTCGGCAACGCGCTTCTTCCCCTTGGCGCAGTGCCCTTGTTCATAGTCGCGCTCGCCATCGTCGCCATGA
TGGTGCTGGTGACCGAATTCGCCAGCAACGTGGCTACCGCCAGCGCGATCATCCCCGTCGTCGCCAGCCTGATCGCCGTA
CTCGGCGCGGACCCGATCCTGCTCGCCATGCCCGCCGCGCTGGCCGCCAGCTGGGGTTTCATGCTGCCCGCTGGCACCGG
GCCCAACGCGATCGCCTGGTCGACCGGCCACATCCGCATCGGCAACATGGTCAAGGCCGGACTGGTGCTGGACCTGATCG
GCATCTTGCTCATCGTGCTGCTCGTGTGGGGCATGGCGAGCCTGTTCTAG

Upstream 100 bases:

>100_bases
CATGAACAGCCCGACCGAAGAAGGCTACGTCGTCGAGTAATCACCCGGGCCGCTTGCCCTCTCTCCTGCCTACGGTAAGG
CAGGGCGGAGGGGGGAATGC

Downstream 100 bases:

>100_bases
AAAAAAAATTCTCTGCCCGCTGCATCCGATCGCACCGCGCGCGGGTAGCTGTTCCCCGGTACACATGAACCGGGGAGATA
ATGATGAAAAAACAAGCACT

Product: related to Na/dicarboxylate cotransporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTAQRIGFVIGLVGLLTGTFAPTPEGMSREAFIVAGLVVLMASWWMTEALPLTATALMPFLVLPFAGVSNARDTAATYYS
PILFLLLGGAFIALAIERTGLHKRLSLAILRTVGSSGGQARLLLAFMISAALLSMLISNTSTSLIMMPMALAVLAGGGIA
ADEREGLAGALPMGIAFAASIGGLGTLVGSPTNAIAVGLLDQTIGVQITFAEWTLYGLPVVICGVPIAALIISRFQQVAA
HPFDVAGARDAIRVGAQWSTAERRLVPVVALTFLLWMTRPLLADYLPAGSLTDGTIAIAASLALFLLPDGTGRPLLVWKE
ADRAPWGVIMMFGGGLALAAGMSASGLAEWLGNALLPLGAVPLFIVALAIVAMMVLVTEFASNVATASAIIPVVASLIAV
LGADPILLAMPAALAASWGFMLPAGTGPNAIAWSTGHIRIGNMVKAGLVLDLIGILLIVLLVWGMASLF

Sequences:

>Translated_469_residues
MTAQRIGFVIGLVGLLTGTFAPTPEGMSREAFIVAGLVVLMASWWMTEALPLTATALMPFLVLPFAGVSNARDTAATYYS
PILFLLLGGAFIALAIERTGLHKRLSLAILRTVGSSGGQARLLLAFMISAALLSMLISNTSTSLIMMPMALAVLAGGGIA
ADEREGLAGALPMGIAFAASIGGLGTLVGSPTNAIAVGLLDQTIGVQITFAEWTLYGLPVVICGVPIAALIISRFQQVAA
HPFDVAGARDAIRVGAQWSTAERRLVPVVALTFLLWMTRPLLADYLPAGSLTDGTIAIAASLALFLLPDGTGRPLLVWKE
ADRAPWGVIMMFGGGLALAAGMSASGLAEWLGNALLPLGAVPLFIVALAIVAMMVLVTEFASNVATASAIIPVVASLIAV
LGADPILLAMPAALAASWGFMLPAGTGPNAIAWSTGHIRIGNMVKAGLVLDLIGILLIVLLVWGMASLF
>Mature_468_residues
TAQRIGFVIGLVGLLTGTFAPTPEGMSREAFIVAGLVVLMASWWMTEALPLTATALMPFLVLPFAGVSNARDTAATYYSP
ILFLLLGGAFIALAIERTGLHKRLSLAILRTVGSSGGQARLLLAFMISAALLSMLISNTSTSLIMMPMALAVLAGGGIAA
DEREGLAGALPMGIAFAASIGGLGTLVGSPTNAIAVGLLDQTIGVQITFAEWTLYGLPVVICGVPIAALIISRFQQVAAH
PFDVAGARDAIRVGAQWSTAERRLVPVVALTFLLWMTRPLLADYLPAGSLTDGTIAIAASLALFLLPDGTGRPLLVWKEA
DRAPWGVIMMFGGGLALAAGMSASGLAEWLGNALLPLGAVPLFIVALAIVAMMVLVTEFASNVATASAIIPVVASLIAVL
GADPILLAMPAALAASWGFMLPAGTGPNAIAWSTGHIRIGNMVKAGLVLDLIGILLIVLLVWGMASLF

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=517, Percent_Identity=30.9477756286267, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4506979, Length=534, Percent_Identity=30.8988764044944, Blast_Score=209, Evalue=7e-54,
Organism=Homo sapiens, GI225637549, Length=583, Percent_Identity=28.3018867924528, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI31377715, Length=520, Percent_Identity=29.8076923076923, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI58761541, Length=516, Percent_Identity=29.8449612403101, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI301069349, Length=496, Percent_Identity=30.0403225806452, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI225637552, Length=489, Percent_Identity=29.4478527607362, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI219802232, Length=448, Percent_Identity=29.4642857142857, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI31795546, Length=352, Percent_Identity=27.8409090909091, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI301069353, Length=346, Percent_Identity=30.9248554913295, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI19923838, Length=337, Percent_Identity=29.3768545994065, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI301069346, Length=157, Percent_Identity=42.0382165605096, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71988385, Length=474, Percent_Identity=31.4345991561181, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI32565804, Length=462, Percent_Identity=31.3852813852814, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71989118, Length=509, Percent_Identity=28.8801571709234, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551790, Length=499, Percent_Identity=24.248496993988, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32564681, Length=489, Percent_Identity=25.3578732106339, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324340, Length=484, Percent_Identity=26.2396694214876, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319885, Length=492, Percent_Identity=26.219512195122, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322263, Length=452, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45551633, Length=531, Percent_Identity=28.6252354048964, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281366409, Length=531, Percent_Identity=28.6252354048964, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI17737623, Length=531, Percent_Identity=28.6252354048964, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24666468, Length=531, Percent_Identity=28.6252354048964, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI281362116, Length=503, Percent_Identity=28.8270377733598, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281362114, Length=503, Percent_Identity=28.6282306163022, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281362112, Length=503, Percent_Identity=28.6282306163022, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI78706796, Length=481, Percent_Identity=28.8981288981289, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI78706798, Length=481, Percent_Identity=28.8981288981289, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 48256; Mature: 48125

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQRIGFVIGLVGLLTGTFAPTPEGMSREAFIVAGLVVLMASWWMTEALPLTATALMPF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVLPFAGVSNARDTAATYYSPILFLLLGGAFIALAIERTGLHKRLSLAILRTVGSSGGQA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHH
RLLLAFMISAALLSMLISNTSTSLIMMPMALAVLAGGGIAADEREGLAGALPMGIAFAAS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
IGGLGTLVGSPTNAIAVGLLDQTIGVQITFAEWTLYGLPVVICGVPIAALIISRFQQVAA
HCCHHHHCCCCCCCEEEEEEHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPFDVAGARDAIRVGAQWSTAERRLVPVVALTFLLWMTRPLLADYLPAGSLTDGTIAIAA
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SLALFLLPDGTGRPLLVWKEADRAPWGVIMMFGGGLALAAGMSASGLAEWLGNALLPLGA
HHHHHEECCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHCCHHHHHHH
VPLFIVALAIVAMMVLVTEFASNVATASAIIPVVASLIAVLGADPILLAMPAALAASWGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MLPAGTGPNAIAWSTGHIRIGNMVKAGLVLDLIGILLIVLLVWGMASLF
EECCCCCCCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAQRIGFVIGLVGLLTGTFAPTPEGMSREAFIVAGLVVLMASWWMTEALPLTATALMPF
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LVLPFAGVSNARDTAATYYSPILFLLLGGAFIALAIERTGLHKRLSLAILRTVGSSGGQA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHH
RLLLAFMISAALLSMLISNTSTSLIMMPMALAVLAGGGIAADEREGLAGALPMGIAFAAS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
IGGLGTLVGSPTNAIAVGLLDQTIGVQITFAEWTLYGLPVVICGVPIAALIISRFQQVAA
HCCHHHHCCCCCCCEEEEEEHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPFDVAGARDAIRVGAQWSTAERRLVPVVALTFLLWMTRPLLADYLPAGSLTDGTIAIAA
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SLALFLLPDGTGRPLLVWKEADRAPWGVIMMFGGGLALAAGMSASGLAEWLGNALLPLGA
HHHHHEECCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHCCHHHHHHH
VPLFIVALAIVAMMVLVTEFASNVATASAIIPVVASLIAVLGADPILLAMPAALAASWGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
MLPAGTGPNAIAWSTGHIRIGNMVKAGLVLDLIGILLIVLLVWGMASLF
EECCCCCCCCEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA