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The map label for this gene is atpD

Identifier: 85374584

GI number: 85374584

Start: 1789933

End: 1791390

Strand: Direct

Name: atpD

Synonym: ELI_08785

Alternate gene names: 85374584

Gene position: 1789933-1791390 (Clockwise)

Preceding gene: 85374583

Following gene: 85374585

Centisome position: 58.64

GC content: 61.93

Gene sequence:

>1458_bases
ATGGCCACCGCACCCGTCCTTAATCAGACCACCAATGGCACGATCAGCCAGGTCATCGGAGCAGTCGTCGACGTGCAGTT
CCCCGGCGAACTGCCCGCGATCCTGACCGCGCTGGAGACCGAGAACGGCGACACCACGCTGGTTCTCGAAGTTGCCCAGC
ATCTGGGTGAGAACACCGTTCGCACCATCGCGATGGACGGGACCGACGGTCTCGTCCGCGGCCAGGAAGTGATCAACACC
GGCGCGCAGATTTCCGTGCCGGTCGGTCCGAAGACGCTCGGCCGCATCATGAACGTGGTCGGCGAACCGATCGACATGCG
CGGCCCGGTCGGCGCCGACAAGGCGAACCCGATCCACGCTGAAGCGCCTGCTTTCGTTGACCAGTCCACCGACGCTGCCA
TCCTCGTCACCGGCATCAAGGTAATCGACTTGCTCGCCCCTTACGCCAAGGGTGGTAAGATCGGCCTGTTCGGCGGTGCC
GGCGTCGGCAAGACCGTGCTGATCCAGGAGCTCATCAACAACATCGCCAAGGGCCACGGCGGTGTGTCCGTCTTCGCCGG
TGTGGGTGAGCGTACCCGCGAAGGTAACGACCTGTATCACGAATTCCTCGACGCAGGCGTCATCGCCAAGAACGAGGCTG
GTGAAGCCATCAGTGAAGGTTCCAAGGTGGCGCTGGTCTTCGGCCAGATGAACGAGCCTCCCGGCGCGCGTGCTCGTGTC
GCTCTGTCGGGTCTGACCATGGCGGAATATTTCCGCGATGAAGAAGGCCAGGACGTGCTGTTCTTCGTCGACAACATCTT
CCGCTTCACGCAGGCCGGTTCGGAAGTGTCCGCCCTCTTGGGCCGTATTCCTTCGGCCGTGGGTTACCAGCCGACCCTGT
CGACCGACATGGGTAACCTGCAGGAGCGTATTACCTCGACCACCAAGGGTTCGATCACCTCGGTGCAGGCCATTTACGTT
CCCGCCGATGACCTTACCGACCCTGCCCCGGCAACCTCGTTTGCTCATTTGGACGCAACGACCACGCTGAACCGCGCGAT
TTCGGAGCTGGGCATCTACCCGGCGGTCGACCCGCTCGATTCCACCAGCCGCGTTCTCGAGCCGCGTGTTGTCGGCCAGG
AGCACTACGAAACTGCCCGTAAGGTCCAGGAAACGCTGCAGAAGTACAAGTCGCTGCAGGACATCATCGCCATTCTCGGC
ATGGACGAGCTGTCGGAAGAAGATAAACTCACCGTCGCCCGTGCGCGCAAGATCCAGAAGTTCCTGTCGCAGCCGTTCCA
TGTTGCCGAAGTCTTTACCGGCATCCCGGGCTGCTTCGTGCAGATCGAAGACACGGTCGCGTCGTTCAAGGCTGTGGTCG
AAGGCGAATACGATCACCTGCCGGAGCAGGCCTTCTACATGGTCGGCGGCATCGACGACGTGGTCGAGAAGGCCAAGAAG
ATGGCCGAGGACGCGTAA

Upstream 100 bases:

>100_bases
GCGACCCTCACCCCGGGCGACGGGGAATGGACGATCGCCGATCCCGAAACCGTTTGCGCCGCTGGCGCCTGAACATCTGA
GCTAGGCTAAGGAAACGAAC

Downstream 100 bases:

>100_bases
GCATCATGGCCCTGCACTTCGAGCTCGTCACGCCCGAACGCCAGGTCCGCTCCGAGGACGTCCACATGGTGGTCGTGCCC
GGCAGCGAAGGCGAGTTCGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MATAPVLNQTTNGTISQVIGAVVDVQFPGELPAILTALETENGDTTLVLEVAQHLGENTVRTIAMDGTDGLVRGQEVINT
GAQISVPVGPKTLGRIMNVVGEPIDMRGPVGADKANPIHAEAPAFVDQSTDAAILVTGIKVIDLLAPYAKGGKIGLFGGA
GVGKTVLIQELINNIAKGHGGVSVFAGVGERTREGNDLYHEFLDAGVIAKNEAGEAISEGSKVALVFGQMNEPPGARARV
ALSGLTMAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGNLQERITSTTKGSITSVQAIYV
PADDLTDPAPATSFAHLDATTTLNRAISELGIYPAVDPLDSTSRVLEPRVVGQEHYETARKVQETLQKYKSLQDIIAILG
MDELSEEDKLTVARARKIQKFLSQPFHVAEVFTGIPGCFVQIEDTVASFKAVVEGEYDHLPEQAFYMVGGIDDVVEKAKK
MAEDA

Sequences:

>Translated_485_residues
MATAPVLNQTTNGTISQVIGAVVDVQFPGELPAILTALETENGDTTLVLEVAQHLGENTVRTIAMDGTDGLVRGQEVINT
GAQISVPVGPKTLGRIMNVVGEPIDMRGPVGADKANPIHAEAPAFVDQSTDAAILVTGIKVIDLLAPYAKGGKIGLFGGA
GVGKTVLIQELINNIAKGHGGVSVFAGVGERTREGNDLYHEFLDAGVIAKNEAGEAISEGSKVALVFGQMNEPPGARARV
ALSGLTMAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGNLQERITSTTKGSITSVQAIYV
PADDLTDPAPATSFAHLDATTTLNRAISELGIYPAVDPLDSTSRVLEPRVVGQEHYETARKVQETLQKYKSLQDIIAILG
MDELSEEDKLTVARARKIQKFLSQPFHVAEVFTGIPGCFVQIEDTVASFKAVVEGEYDHLPEQAFYMVGGIDDVVEKAKK
MAEDA
>Mature_484_residues
ATAPVLNQTTNGTISQVIGAVVDVQFPGELPAILTALETENGDTTLVLEVAQHLGENTVRTIAMDGTDGLVRGQEVINTG
AQISVPVGPKTLGRIMNVVGEPIDMRGPVGADKANPIHAEAPAFVDQSTDAAILVTGIKVIDLLAPYAKGGKIGLFGGAG
VGKTVLIQELINNIAKGHGGVSVFAGVGERTREGNDLYHEFLDAGVIAKNEAGEAISEGSKVALVFGQMNEPPGARARVA
LSGLTMAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGNLQERITSTTKGSITSVQAIYVP
ADDLTDPAPATSFAHLDATTTLNRAISELGIYPAVDPLDSTSRVLEPRVVGQEHYETARKVQETLQKYKSLQDIIAILGM
DELSEEDKLTVARARKIQKFLSQPFHVAEVFTGIPGCFVQIEDTVASFKAVVEGEYDHLPEQAFYMVGGIDDVVEKAKKM
AEDA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=473, Percent_Identity=75.4756871035941, Blast_Score=729, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=306, Percent_Identity=28.7581699346405, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913428, Length=457, Percent_Identity=24.72647702407, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19913426, Length=418, Percent_Identity=25.1196172248804, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI50345984, Length=401, Percent_Identity=25.1870324189526, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4757810, Length=401, Percent_Identity=25.1870324189526, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790170, Length=471, Percent_Identity=67.9405520169851, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=417, Percent_Identity=27.8177458033573, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790172, Length=458, Percent_Identity=24.8908296943231, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=73.5169491525424, Blast_Score=709, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=306, Percent_Identity=28.7581699346405, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=25.4901960784314, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=443, Percent_Identity=25.0564334085779, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=311, Percent_Identity=26.0450160771704, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71988080, Length=311, Percent_Identity=26.0450160771704, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=317, Percent_Identity=23.9747634069401, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=465, Percent_Identity=77.8494623655914, Blast_Score=726, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=384, Percent_Identity=25, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=431, Percent_Identity=25.0580046403712, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320016, Length=283, Percent_Identity=23.321554770318, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24638766, Length=474, Percent_Identity=75.7383966244726, Blast_Score=729, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=472, Percent_Identity=69.2796610169492, Blast_Score=654, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=70.3296703296703, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI20129479, Length=306, Percent_Identity=28.7581699346405, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583992, Length=306, Percent_Identity=28.4313725490196, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24583988, Length=305, Percent_Identity=28.5245901639344, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583986, Length=305, Percent_Identity=28.5245901639344, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583984, Length=305, Percent_Identity=28.5245901639344, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281361666, Length=448, Percent_Identity=24.7767857142857, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646341, Length=448, Percent_Identity=24.7767857142857, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17136796, Length=448, Percent_Identity=24.7767857142857, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24658560, Length=311, Percent_Identity=26.0450160771704, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_ERYLH (Q2N8Z2)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458646.1
- HSSP:   P00829
- ProteinModelPortal:   Q2N8Z2
- SMR:   Q2N8Z2
- STRING:   Q2N8Z2
- GeneID:   3868958
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_08785
- NMPDR:   fig|314225.3.peg.1286
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q2N8Z2
- ProtClustDB:   PRK09280
- BioCyc:   ELIT314225:ELI_08785-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51535; Mature: 51404

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAPVLNQTTNGTISQVIGAVVDVQFPGELPAILTALETENGDTTLVLEVAQHLGENTV
CCCCCCCCCCCCCHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCEEEHHHHHHHCCCCCE
RTIAMDGTDGLVRGQEVINTGAQISVPVGPKTLGRIMNVVGEPIDMRGPVGADKANPIHA
EEEEECCCCCHHCCHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EAPAFVDQSTDAAILVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNIAKGHG
CCCCHHCCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
GVSVFAGVGERTREGNDLYHEFLDAGVIAKNEAGEAISEGSKVALVFGQMNEPPGARARV
CEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHCCCEEEEEEECCCCCCCCCEEE
ALSGLTMAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGNL
EEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCCCCCHHHH
QERITSTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLNRAISELGIYPAVDPLD
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCC
STSRVLEPRVVGQEHYETARKVQETLQKYKSLQDIIAILGMDELSEEDKLTVARARKIQK
CHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHH
FLSQPFHVAEVFTGIPGCFVQIEDTVASFKAVVEGEYDHLPEQAFYMVGGIDDVVEKAKK
HHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCHHCCCHHHHEECCCHHHHHHHHHH
MAEDA
HHCCC
>Mature Secondary Structure 
ATAPVLNQTTNGTISQVIGAVVDVQFPGELPAILTALETENGDTTLVLEVAQHLGENTV
CCCCCCCCCCCCHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCEEEHHHHHHHCCCCCE
RTIAMDGTDGLVRGQEVINTGAQISVPVGPKTLGRIMNVVGEPIDMRGPVGADKANPIHA
EEEEECCCCCHHCCHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EAPAFVDQSTDAAILVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNIAKGHG
CCCCHHCCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
GVSVFAGVGERTREGNDLYHEFLDAGVIAKNEAGEAISEGSKVALVFGQMNEPPGARARV
CEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHCCCEEEEEEECCCCCCCCCEEE
ALSGLTMAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGNL
EEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCCCCCHHHH
QERITSTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLNRAISELGIYPAVDPLD
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCCC
STSRVLEPRVVGQEHYETARKVQETLQKYKSLQDIIAILGMDELSEEDKLTVARARKIQK
CHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHH
FLSQPFHVAEVFTGIPGCFVQIEDTVASFKAVVEGEYDHLPEQAFYMVGGIDDVVEKAKK
HHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCHHCCCHHHHEECCCHHHHHHHHHH
MAEDA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA