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The map label for this gene is uvrA [H]

Identifier: 85374406

GI number: 85374406

Start: 1632933

End: 1633127

Strand: Reverse

Name: uvrA [H]

Synonym: ELI_07895

Alternate gene names: 85374406

Gene position: 1633127-1632933 (Counterclockwise)

Preceding gene: 85374407

Following gene: 85374405

Centisome position: 53.5

GC content: 60.51

Gene sequence:

>195_bases
GTGGTGGTGATCGAGCACAATCTGGATGTGATCAAGACTGCGGATCATATCCTTGATCTTGGGCCGGATGGCGGTGTGCG
GGGTGGCGAGGTTGTCGCGCAGGGTGCCCCCGAAGAGGTTGCGACGGTGAAGGGGAGTTATACGGGGCAGTATTTGAAAC
CGATGCTGGAGCGGCAGGCGGAGGCGGCGGAATAG

Upstream 100 bases:

>100_bases
AGCGCAGTTTCACCGGCCAGTACCTAGCCCCGCTACTGACACGCCGGAAGAAAACTGCCGCATGACGATGACAGAAGGCC
TGCCCCGGACTTGATCCGGG

Downstream 100 bases:

>100_bases
GTGCTTAAAGATGTAGTATGATGAATGCTGTCGATTAATTCGAGTGCGGACTACATGCGTTCGCCATTCTCAAGTACGTT
TGCGCCATGCGACTTGAGAC

Product: excinuclease ABC subunit A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 64; Mature: 64

Protein sequence:

>64_residues
MVVIEHNLDVIKTADHILDLGPDGGVRGGEVVAQGAPEEVATVKGSYTGQYLKPMLERQAEAAE

Sequences:

>Translated_64_residues
MVVIEHNLDVIKTADHILDLGPDGGVRGGEVVAQGAPEEVATVKGSYTGQYLKPMLERQAEAAE
>Mature_64_residues
MVVIEHNLDVIKTADHILDLGPDGGVRGGEVVAQGAPEEVATVKGSYTGQYLKPMLERQAEAAE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=52, Percent_Identity=51.9230769230769, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR003593
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 6775; Mature: 6775

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIEHNLDVIKTADHILDLGPDGGVRGGEVVAQGAPEEVATVKGSYTGQYLKPMLERQA
CEEECCCCCEEEHHHHHEECCCCCCCCCCEEEECCCCCHHEECCCCCCCHHHHHHHHHHH
EAAE
CCCC
>Mature Secondary Structure
MVVIEHNLDVIKTADHILDLGPDGGVRGGEVVAQGAPEEVATVKGSYTGQYLKPMLERQA
CEEECCCCCEEEHHHHHEECCCCCCCCCCEEEECCCCCHHEECCCCCCCHHHHHHHHHHH
EAAE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]