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The map label for this gene is glcD [H]

Identifier: 85374362

GI number: 85374362

Start: 1587300

End: 1588748

Strand: Direct

Name: glcD [H]

Synonym: ELI_07675

Alternate gene names: 85374362

Gene position: 1587300-1588748 (Clockwise)

Preceding gene: 85374358

Following gene: 85374363

Centisome position: 52.0

GC content: 63.7

Gene sequence:

>1449_bases
ATGGCCGATATGCAGACTTTCTTCGCACGCGCAGCCGCTATGCTCGGCCCCAAGGGCTTCACGCAGGATCCGGACGTGAT
CGAGCCGTGGCTGACGGACTGGCGCGGGCGCTACACCGGACGAGCCTTGGCCCTCGCCTCGCCCGGCTCGACACGGGACG
TCGCGAAACTGGTTCAGCTTTGCGGGGAATTCGGAGTTCCGATCGTTCCCCAGGGCGGCAATACCGGCATGTGCGGGGGA
GCAACGCCGGATGACACGGGGTCCGCCATCCTGCTCTCGCTGCGCCGGATGGACGCGATCCGGTCGCTCGATCCCGATGC
CCGGCAGGTCGTGTGCGAAGCCGGGGTAATTCTGCAGACGCTCCATGAAGCGGCGGCGGCGGAAGGGCTGCGCTTCCCCC
TCACACTGGGCGGCAAGGGCTCGGCAACGATCGGCGGCTTGATCTCCACCAATGCCGGGGGCACGCAGGTTTTGCGACAC
GGTACGATGCGGGCTCAGGTGCTGGGTATCGAAGCGGTCATGCCCGATGGCAACGTGTTTGAGGGCTTGGTGCCCCTCAA
GAAGGACAATCGCGGTTTCGACCTCAAGCAATTGCTGATCGGGTCCGAGGGGACGCTGGGCATTATTACTGCCGCTAGCC
TGCAATTGCAGCCCGCGATCGGCGGACGACGGGTGCTCTGGATCGGGCTGAAAAGCATCCAGCAAGCGCGGCAATTGTTG
CTTCATGCGCAGTCTTCGGTCGGCGACGCGCTCGAGGGTTTCGAGGTCGTGCCGCGCCACAGCCTTGAGGCAGTCCTGGA
TTATTTACCTGAAGCGCGCGATCCGCTGCAGAATTCCCATCCATGGTATGCGCTGGTCGAACTGGTGGCGACCGCCGGCA
TGGGAGACGCGCTCGATGCGCGGGCCGAGGGGTTGCTCGAGGGCGCTTATCACGATGGGCTCCTCGAAGATGCCACCATC
GCCGCAAATGAAACTCAGGCGGAGGAACTATGGCTTTTGCGCGACTCGATCGCCCCTGCCGAGCGGGCGATCGGCCCGGC
CATGCAGCACGACATTTCCGTGCCCGTCGCGAAAATGGCCGATTTCGTCGAGCTGGTCTCGCCCGAGATGGAACGACGCT
TCCCGGGGACCAGAGCTGTCGCTTTCGGTCACCTCGGTGATGGCAATGTGCATTTTCACATTCTTGCGCCCGACAACGCC
ATCCGCGGCGAATGGGAAGAAAACGAGGGCAAGGCGATCAGCGCAGTCGTCCACGATCTCGTCACCGAATGGGGTGGTTC
GATAAGCGCAGAGCATGGGATCGGCCAGATGAAGCGCGACGAGTTGGCTCGTCTGGGCCATCCCGCAAGCCTCGCGATGA
TGCGCAGCGTCAAGCAGGCGCTCGACCCGCAAGGACTGTTCAATCCCGGCAAGCTCGTTCCCCTTGCGCGCGAGAGCACA
AGCCCCTAA

Upstream 100 bases:

>100_bases
GGGGCCAATTGAATGCTGGCTTAATCCCGATCTCGCAAACCGCAAGGAAGCGCACAAATACTGGCATTGCAGCCCTTCCC
TGTGGCAGAGACGACACTGT

Downstream 100 bases:

>100_bases
AGCGCTCGCCCATCACGCGCGGTGGCGGAGGGTCGCTGCTCGCGAGACCAGCCTCACGTTTTCGGAGATTATCCATGGCC
AGCGCGCCGCAGCCCAGCCT

Product: FAD/FMN-containing dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MADMQTFFARAAAMLGPKGFTQDPDVIEPWLTDWRGRYTGRALALASPGSTRDVAKLVQLCGEFGVPIVPQGGNTGMCGG
ATPDDTGSAILLSLRRMDAIRSLDPDARQVVCEAGVILQTLHEAAAAEGLRFPLTLGGKGSATIGGLISTNAGGTQVLRH
GTMRAQVLGIEAVMPDGNVFEGLVPLKKDNRGFDLKQLLIGSEGTLGIITAASLQLQPAIGGRRVLWIGLKSIQQARQLL
LHAQSSVGDALEGFEVVPRHSLEAVLDYLPEARDPLQNSHPWYALVELVATAGMGDALDARAEGLLEGAYHDGLLEDATI
AANETQAEELWLLRDSIAPAERAIGPAMQHDISVPVAKMADFVELVSPEMERRFPGTRAVAFGHLGDGNVHFHILAPDNA
IRGEWEENEGKAISAVVHDLVTEWGGSISAEHGIGQMKRDELARLGHPASLAMMRSVKQALDPQGLFNPGKLVPLAREST
SP

Sequences:

>Translated_482_residues
MADMQTFFARAAAMLGPKGFTQDPDVIEPWLTDWRGRYTGRALALASPGSTRDVAKLVQLCGEFGVPIVPQGGNTGMCGG
ATPDDTGSAILLSLRRMDAIRSLDPDARQVVCEAGVILQTLHEAAAAEGLRFPLTLGGKGSATIGGLISTNAGGTQVLRH
GTMRAQVLGIEAVMPDGNVFEGLVPLKKDNRGFDLKQLLIGSEGTLGIITAASLQLQPAIGGRRVLWIGLKSIQQARQLL
LHAQSSVGDALEGFEVVPRHSLEAVLDYLPEARDPLQNSHPWYALVELVATAGMGDALDARAEGLLEGAYHDGLLEDATI
AANETQAEELWLLRDSIAPAERAIGPAMQHDISVPVAKMADFVELVSPEMERRFPGTRAVAFGHLGDGNVHFHILAPDNA
IRGEWEENEGKAISAVVHDLVTEWGGSISAEHGIGQMKRDELARLGHPASLAMMRSVKQALDPQGLFNPGKLVPLAREST
SP
>Mature_481_residues
ADMQTFFARAAAMLGPKGFTQDPDVIEPWLTDWRGRYTGRALALASPGSTRDVAKLVQLCGEFGVPIVPQGGNTGMCGGA
TPDDTGSAILLSLRRMDAIRSLDPDARQVVCEAGVILQTLHEAAAAEGLRFPLTLGGKGSATIGGLISTNAGGTQVLRHG
TMRAQVLGIEAVMPDGNVFEGLVPLKKDNRGFDLKQLLIGSEGTLGIITAASLQLQPAIGGRRVLWIGLKSIQQARQLLL
HAQSSVGDALEGFEVVPRHSLEAVLDYLPEARDPLQNSHPWYALVELVATAGMGDALDARAEGLLEGAYHDGLLEDATIA
ANETQAEELWLLRDSIAPAERAIGPAMQHDISVPVAKMADFVELVSPEMERRFPGTRAVAFGHLGDGNVHFHILAPDNAI
RGEWEENEGKAISAVVHDLVTEWGGSISAEHGIGQMKRDELARLGHPASLAMMRSVKQALDPQGLFNPGKLVPLARESTS
P

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=463, Percent_Identity=36.0691144708423, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI37595756, Length=437, Percent_Identity=30.4347826086957, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI37595754, Length=460, Percent_Identity=29.3478260869565, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4501993, Length=468, Percent_Identity=23.9316239316239, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789351, Length=461, Percent_Identity=29.2841648590022, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1787977, Length=516, Percent_Identity=26.5503875968992, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI48994907, Length=452, Percent_Identity=20.353982300885, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534361, Length=474, Percent_Identity=31.2236286919831, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71992373, Length=449, Percent_Identity=27.6169265033408, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71992381, Length=442, Percent_Identity=27.6018099547511, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71992392, Length=396, Percent_Identity=27.7777777777778, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=173, Percent_Identity=24.2774566473988, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320023, Length=451, Percent_Identity=33.7028824833703, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6320764, Length=463, Percent_Identity=30.8855291576674, Blast_Score=277, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6320027, Length=440, Percent_Identity=24.7727272727273, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18921117, Length=457, Percent_Identity=33.4792122538293, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24639277, Length=457, Percent_Identity=33.4792122538293, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24639275, Length=457, Percent_Identity=33.4792122538293, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24653753, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51278; Mature: 51147

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADMQTFFARAAAMLGPKGFTQDPDVIEPWLTDWRGRYTGRALALASPGSTRDVAKLVQL
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
CGEFGVPIVPQGGNTGMCGGATPDDTGSAILLSLRRMDAIRSLDPDARQVVCEAGVILQT
HHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHEAAAAEGLRFPLTLGGKGSATIGGLISTNAGGTQVLRHGTMRAQVLGIEAVMPDGNVF
HHHHHHHCCCCCEEEECCCCCCEECCEEECCCCHHHHHHHCCCEEEEEEEEEECCCCCHH
EGLVPLKKDNRGFDLKQLLIGSEGTLGIITAASLQLQPAIGGRRVLWIGLKSIQQARQLL
HCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHH
LHAQSSVGDALEGFEVVPRHSLEAVLDYLPEARDPLQNSHPWYALVELVATAGMGDALDA
HHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHH
RAEGLLEGAYHDGLLEDATIAANETQAEELWLLRDSIAPAERAIGPAMQHDISVPVAKMA
HHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHCHHHHHCCCCCHHHHH
DFVELVSPEMERRFPGTRAVAFGHLGDGNVHFHILAPDNAIRGEWEENEGKAISAVVHDL
HHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VTEWGGSISAEHGIGQMKRDELARLGHPASLAMMRSVKQALDPQGLFNPGKLVPLAREST
HHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
SP
CC
>Mature Secondary Structure 
ADMQTFFARAAAMLGPKGFTQDPDVIEPWLTDWRGRYTGRALALASPGSTRDVAKLVQL
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
CGEFGVPIVPQGGNTGMCGGATPDDTGSAILLSLRRMDAIRSLDPDARQVVCEAGVILQT
HHHCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHEAAAAEGLRFPLTLGGKGSATIGGLISTNAGGTQVLRHGTMRAQVLGIEAVMPDGNVF
HHHHHHHCCCCCEEEECCCCCCEECCEEECCCCHHHHHHHCCCEEEEEEEEEECCCCCHH
EGLVPLKKDNRGFDLKQLLIGSEGTLGIITAASLQLQPAIGGRRVLWIGLKSIQQARQLL
HCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHH
LHAQSSVGDALEGFEVVPRHSLEAVLDYLPEARDPLQNSHPWYALVELVATAGMGDALDA
HHHHHHHHHHHHCCHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHH
RAEGLLEGAYHDGLLEDATIAANETQAEELWLLRDSIAPAERAIGPAMQHDISVPVAKMA
HHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHCHHHHHCCCCCHHHHH
DFVELVSPEMERRFPGTRAVAFGHLGDGNVHFHILAPDNAIRGEWEENEGKAISAVVHDL
HHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
VTEWGGSISAEHGIGQMKRDELARLGHPASLAMMRSVKQALDPQGLFNPGKLVPLAREST
HHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
SP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]