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The map label for this gene is amn [H]

Identifier: 85374302

GI number: 85374302

Start: 1531098

End: 1532537

Strand: Direct

Name: amn [H]

Synonym: ELI_07375

Alternate gene names: 85374302

Gene position: 1531098-1532537 (Clockwise)

Preceding gene: 85374301

Following gene: 85374303

Centisome position: 50.16

GC content: 65.0

Gene sequence:

>1440_bases
ATGGAAAACATCGATACGATTCTGGCGGAACTGGTCCGCCTGTACGACGAGGCGACGCAGCGCCTTCGCAATGACATCCT
CGCCTATGCACGCGACGGCAAGCTGCCGAGCAAGACCCGCCGCACCGACGGTTCCTATGCCTATCCGGAGTTGCGGATGG
TCTATCGCGGCGGGCCATTGCTGGCCGAACAGGGCCGCGCCTTCGGACGGCTTAACGACAGCGGCACCTATGCCACCACC
GTTACCAAGCCGCGTCTCTTCGACGATTACCTGCGCGAACAGCTGGAGCTTATTCGCGAGGAACACGACGTCGAGATAGA
AGTCCGCGCCTCGCGCCAGGAAATCCCTTTCCCCTACGTGCTGGACGGCGAGGCGGGGGCCGAGCTTGCCGGTGTCTCCC
CGCAGGAAATCGCGCGGCATTTCCCCCACACCGATCTCGCCGATATCGGGGACGAGCTGGCCGACGGAATCGAGCTGGAG
GGGCCCGACGATGTCATCCCGCTCAGCCTGTTCGACGGTCTGCGCACCGACTTCAGCCTCGCGCGGCTTGCGCATTACAC
CGGCACCGATACGCAGCACTTCCAGCGCTACATCCTGTTTACGAACTATCACCGCTATGTCGATGAATTCGTTGACTGGG
CGGGCGAGCAGCTGGGCTCCAACCGCTATACCGCGCTGGCCGGAGCGGGCGGCCTGCTGCTCGACACTAGGACTTCCAAC
GCCCGCGCGCAGCTTTCCGACACGGCGTGGCGCAAGCACCAGATGCCGGCTTACCACCTGATTGCCGAGGGCGGTGCCGG
CATCACACTCGTGAATATCGGCGTCGGCCCCTCCAACGCGAAGACGATCTGCGATCACTTGGCCGTGCTGCGGCCCGAGG
CGTGGCTGATGATCGGCCATTGCGGGGGCCTGCGCGGCAGCCAGCGGATCGGCGACTACGTGCTGGCCCACGCCTATTTG
CGCGACGATCACGTGCTCGATCCCGTCCTGCCGCCGGAGATCCCCCTTCCCGCCATCGCCGAGGTGCAGCAGGCGCTGGT
CGGTGCAGCGGTAGAGATCAGCGGGGAGGCGGGCGCCGATCTCAAGAAGCGCATGCGCACCGGCACCGTCGTCACCACAG
ACGACCGCAACTGGGAGCTGCGCTATACCACGTCGGCCAAACGCCTCTCGCTCAGCCGCGCGGTCGGGATCGACATGGAA
AGCGCGACCATCGCGGCGCAGGGCTATCGCTTCCGTGTGCCCTACGGAACGCTGCTGTGCGTCAGCGACAAGCCGCTCCA
TGGTGAGATCAAGCTGCCGGGACAGGCGAACAAGTTCTACGAGGAAGCCATCGCCGCGCATCTCCAGATCGGCGTGAAGG
CGATCGACCTGATGCGCGCGGAAGGCCAGCGATTGCACAGCCGCAAGCTACGCGCCTTCAACGAGCCGCCGTTCAGGTAA

Upstream 100 bases:

>100_bases
CTGATTTCGGCGCATCGGAACAGAAACAGGGGCGCGGGGCTACAAGCTTCGCGCCCCTTTTCTTTGCGGCTACGCATTTC
GGCGCTAAGGGCCGGGCCTC

Downstream 100 bases:

>100_bases
GGCGCGCTAAGTCCCCTCCCGCCTGCGGGAGGGGCAGCGAGACTTACGAGCTTGCTCGCTAGTCGCAGCGGGTTGGGCAA
ATCCCATCTGTCGTGGCTCC

Product: AMP nucleosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MENIDTILAELVRLYDEATQRLRNDILAYARDGKLPSKTRRTDGSYAYPELRMVYRGGPLLAEQGRAFGRLNDSGTYATT
VTKPRLFDDYLREQLELIREEHDVEIEVRASRQEIPFPYVLDGEAGAELAGVSPQEIARHFPHTDLADIGDELADGIELE
GPDDVIPLSLFDGLRTDFSLARLAHYTGTDTQHFQRYILFTNYHRYVDEFVDWAGEQLGSNRYTALAGAGGLLLDTRTSN
ARAQLSDTAWRKHQMPAYHLIAEGGAGITLVNIGVGPSNAKTICDHLAVLRPEAWLMIGHCGGLRGSQRIGDYVLAHAYL
RDDHVLDPVLPPEIPLPAIAEVQQALVGAAVEISGEAGADLKKRMRTGTVVTTDDRNWELRYTTSAKRLSLSRAVGIDME
SATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANKFYEEAIAAHLQIGVKAIDLMRAEGQRLHSRKLRAFNEPPFR

Sequences:

>Translated_479_residues
MENIDTILAELVRLYDEATQRLRNDILAYARDGKLPSKTRRTDGSYAYPELRMVYRGGPLLAEQGRAFGRLNDSGTYATT
VTKPRLFDDYLREQLELIREEHDVEIEVRASRQEIPFPYVLDGEAGAELAGVSPQEIARHFPHTDLADIGDELADGIELE
GPDDVIPLSLFDGLRTDFSLARLAHYTGTDTQHFQRYILFTNYHRYVDEFVDWAGEQLGSNRYTALAGAGGLLLDTRTSN
ARAQLSDTAWRKHQMPAYHLIAEGGAGITLVNIGVGPSNAKTICDHLAVLRPEAWLMIGHCGGLRGSQRIGDYVLAHAYL
RDDHVLDPVLPPEIPLPAIAEVQQALVGAAVEISGEAGADLKKRMRTGTVVTTDDRNWELRYTTSAKRLSLSRAVGIDME
SATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANKFYEEAIAAHLQIGVKAIDLMRAEGQRLHSRKLRAFNEPPFR
>Mature_479_residues
MENIDTILAELVRLYDEATQRLRNDILAYARDGKLPSKTRRTDGSYAYPELRMVYRGGPLLAEQGRAFGRLNDSGTYATT
VTKPRLFDDYLREQLELIREEHDVEIEVRASRQEIPFPYVLDGEAGAELAGVSPQEIARHFPHTDLADIGDELADGIELE
GPDDVIPLSLFDGLRTDFSLARLAHYTGTDTQHFQRYILFTNYHRYVDEFVDWAGEQLGSNRYTALAGAGGLLLDTRTSN
ARAQLSDTAWRKHQMPAYHLIAEGGAGITLVNIGVGPSNAKTICDHLAVLRPEAWLMIGHCGGLRGSQRIGDYVLAHAYL
RDDHVLDPVLPPEIPLPAIAEVQQALVGAAVEISGEAGADLKKRMRTGTVVTTDDRNWELRYTTSAKRLSLSRAVGIDME
SATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANKFYEEAIAAHLQIGVKAIDLMRAEGQRLHSRKLRAFNEPPFR

Specific function: Involved in regulation of AMP concentrations [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788293, Length=474, Percent_Identity=62.4472573839662, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011271
- InterPro:   IPR018953
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF10423 AMNp_N; PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.4 [H]

Molecular weight: Translated: 53230; Mature: 53230

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIDTILAELVRLYDEATQRLRNDILAYARDGKLPSKTRRTDGSYAYPELRMVYRGGPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEEECCCCE
LAEQGRAFGRLNDSGTYATTVTKPRLFDDYLREQLELIREEHDVEIEVRASRQEIPFPYV
EHHCCCHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEE
LDGEAGAELAGVSPQEIARHFPHTDLADIGDELADGIELEGPDDVIPLSLFDGLRTDFSL
ECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCHHH
ARLAHYTGTDTQHFQRYILFTNYHRYVDEFVDWAGEQLGSNRYTALAGAGGLLLDTRTSN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCC
ARAQLSDTAWRKHQMPAYHLIAEGGAGITLVNIGVGPSNAKTICDHLAVLRPEAWLMIGH
CCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEE
CGGLRGSQRIGDYVLAHAYLRDDHVLDPVLPPEIPLPAIAEVQQALVGAAVEISGEAGAD
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCHH
LKKRMRTGTVVTTDDRNWELRYTTSAKRLSLSRAVGIDMESATIAAQGYRFRVPYGTLLC
HHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEE
VSDKPLHGEIKLPGQANKFYEEAIAAHLQIGVKAIDLMRAEGQRLHSRKLRAFNEPPFR
ECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MENIDTILAELVRLYDEATQRLRNDILAYARDGKLPSKTRRTDGSYAYPELRMVYRGGPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEEECCCCE
LAEQGRAFGRLNDSGTYATTVTKPRLFDDYLREQLELIREEHDVEIEVRASRQEIPFPYV
EHHCCCHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEE
LDGEAGAELAGVSPQEIARHFPHTDLADIGDELADGIELEGPDDVIPLSLFDGLRTDFSL
ECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCHHH
ARLAHYTGTDTQHFQRYILFTNYHRYVDEFVDWAGEQLGSNRYTALAGAGGLLLDTRTSN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCC
ARAQLSDTAWRKHQMPAYHLIAEGGAGITLVNIGVGPSNAKTICDHLAVLRPEAWLMIGH
CCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEE
CGGLRGSQRIGDYVLAHAYLRDDHVLDPVLPPEIPLPAIAEVQQALVGAAVEISGEAGAD
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCHH
LKKRMRTGTVVTTDDRNWELRYTTSAKRLSLSRAVGIDMESATIAAQGYRFRVPYGTLLC
HHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEE
VSDKPLHGEIKLPGQANKFYEEAIAAHLQIGVKAIDLMRAEGQRLHSRKLRAFNEPPFR
ECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]