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The map label for this gene is prmA [H]

Identifier: 85374263

GI number: 85374263

Start: 1485103

End: 1486023

Strand: Direct

Name: prmA [H]

Synonym: ELI_07180

Alternate gene names: 85374263

Gene position: 1485103-1486023 (Clockwise)

Preceding gene: 85374262

Following gene: 85374264

Centisome position: 48.65

GC content: 66.45

Gene sequence:

>921_bases
ATGACTGCGAGCTGGAAACTCACCGCCTTTGCGCCGAAGCCCGTGATACAGTCCGCGCTCCTCGCGCATGACGAGGCGTG
GGACTGGGACGATGCGGTGGTCATCTCGGGACGCGAAGTGGCGGAAGACCGGCCCGAGGACTGGGTGCTCGAATGCTGGT
ACCCGCGCCGACCGACCAAGGCGGACAAGCAGGCGGCCGCCGCCCTGTTCGCGGGCGAGGCTCCGCCTTTCGAAGTCGAG
AAACTCCCGGAAGAGGACTGGGTGACGCTCAGCCAGCAGGGCGTCGAGCCGATCCGGGCGGCGCGCTTCTACGTCCACAC
CCCCGACTTCCCGCCTGATGACACACCCGGCACGGTCAACTTCGCGATCCCCGCCAGCCAAGCCTTCGGTACCGGCCAGC
ACGAGACGACCGCCGGATGTCTCGCGATGCTGGACCTGATGAAGCGGCAGGGCGTTTCAGCGCGCAACATCGCCGATATC
GGCACAGGCACTGGGCTGCTCGCGTTCGGCGCCTTGAGGCTGTGGCCACATGCTACGATGACCGCGACCGATATCGACGC
GAATTGCGTGCCGGTCATCGAAGCCAATGCCGCCACCAACGGCATCGCGCAGGGGAGCGGGCCGGGCGAAATGACGATGA
TCGTCGCTGCGGGCACCGACCATTCGCTGATCGCTGCGCGCGGCCCCTACGACTTGCTGATCGCCAATATCCTCGCCGGG
CCGCTGGTCGATCTGGCCGGGGATTTCGCCGCGCATGTCGCTCCTGGCGGGCATCTGCTATTGGCAGGGCTGCTGGAAAC
ACAGGAAGCGCGGGTGCGCGCCGCTTACCGGCGTGCCGGATTTCGCCTCGCCAAGAGGCTCGTGAACGGAGACTGGTCGA
TCCTATGGATGCGAAAGCGTATCGGACGCAACGCGGGCTGA

Upstream 100 bases:

>100_bases
TCCAGACTGGGAGGACAGGTTTGCAGACCTGGTCATGTTGTAGGAAGCTGGATCCCCGCCTGCGCGGGGATGACGGAGAA
AAAGAGAAATCGAACTGGAC

Downstream 100 bases:

>100_bases
AGCCCTGGTTCGGCGGTACGCTCCGGATCCTCGGCATCGCGGTCGGCGCATTGCTGCTCCTCGTCCTGGCCTTCCTGCTG
TCGGCCTGGATCGGCAGTTC

Product: ribosomal protein L11 methylase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTASWKLTAFAPKPVIQSALLAHDEAWDWDDAVVISGREVAEDRPEDWVLECWYPRRPTKADKQAAAALFAGEAPPFEVE
KLPEEDWVTLSQQGVEPIRAARFYVHTPDFPPDDTPGTVNFAIPASQAFGTGQHETTAGCLAMLDLMKRQGVSARNIADI
GTGTGLLAFGALRLWPHATMTATDIDANCVPVIEANAATNGIAQGSGPGEMTMIVAAGTDHSLIAARGPYDLLIANILAG
PLVDLAGDFAAHVAPGGHLLLAGLLETQEARVRAAYRRAGFRLAKRLVNGDWSILWMRKRIGRNAG

Sequences:

>Translated_306_residues
MTASWKLTAFAPKPVIQSALLAHDEAWDWDDAVVISGREVAEDRPEDWVLECWYPRRPTKADKQAAAALFAGEAPPFEVE
KLPEEDWVTLSQQGVEPIRAARFYVHTPDFPPDDTPGTVNFAIPASQAFGTGQHETTAGCLAMLDLMKRQGVSARNIADI
GTGTGLLAFGALRLWPHATMTATDIDANCVPVIEANAATNGIAQGSGPGEMTMIVAAGTDHSLIAARGPYDLLIANILAG
PLVDLAGDFAAHVAPGGHLLLAGLLETQEARVRAAYRRAGFRLAKRLVNGDWSILWMRKRIGRNAG
>Mature_305_residues
TASWKLTAFAPKPVIQSALLAHDEAWDWDDAVVISGREVAEDRPEDWVLECWYPRRPTKADKQAAAALFAGEAPPFEVEK
LPEEDWVTLSQQGVEPIRAARFYVHTPDFPPDDTPGTVNFAIPASQAFGTGQHETTAGCLAMLDLMKRQGVSARNIADIG
TGTGLLAFGALRLWPHATMTATDIDANCVPVIEANAATNGIAQGSGPGEMTMIVAAGTDHSLIAARGPYDLLIANILAGP
LVDLAGDFAAHVAPGGHLLLAGLLETQEARVRAAYRRAGFRLAKRLVNGDWSILWMRKRIGRNAG

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32825; Mature: 32693

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASWKLTAFAPKPVIQSALLAHDEAWDWDDAVVISGREVAEDRPEDWVLECWYPRRPTK
CCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCHHHCCCCCCCEEEEECCCCCCC
ADKQAAAALFAGEAPPFEVEKLPEEDWVTLSQQGVEPIRAARFYVHTPDFPPDDTPGTVN
HHHHHHHHHHCCCCCCCHHHHCCCHHHEEHHHHCCCHHHHEEEEEECCCCCCCCCCCEEE
FAIPASQAFGTGQHETTAGCLAMLDLMKRQGVSARNIADIGTGTGLLAFGALRLWPHATM
EEEECHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCCEE
TATDIDANCVPVIEANAATNGIAQGSGPGEMTMIVAAGTDHSLIAARGPYDLLIANILAG
EEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHH
PLVDLAGDFAAHVAPGGHLLLAGLLETQEARVRAAYRRAGFRLAKRLVNGDWSILWMRKR
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH
IGRNAG
HCCCCC
>Mature Secondary Structure 
TASWKLTAFAPKPVIQSALLAHDEAWDWDDAVVISGREVAEDRPEDWVLECWYPRRPTK
CCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCHHHCCCCCCCEEEEECCCCCCC
ADKQAAAALFAGEAPPFEVEKLPEEDWVTLSQQGVEPIRAARFYVHTPDFPPDDTPGTVN
HHHHHHHHHHCCCCCCCHHHHCCCHHHEEHHHHCCCHHHHEEEEEECCCCCCCCCCCEEE
FAIPASQAFGTGQHETTAGCLAMLDLMKRQGVSARNIADIGTGTGLLAFGALRLWPHATM
EEEECHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCCEE
TATDIDANCVPVIEANAATNGIAQGSGPGEMTMIVAAGTDHSLIAARGPYDLLIANILAG
EEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHH
PLVDLAGDFAAHVAPGGHLLLAGLLETQEARVRAAYRRAGFRLAKRLVNGDWSILWMRKR
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH
IGRNAG
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]