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The map label for this gene is hlyB [H]

Identifier: 85374015

GI number: 85374015

Start: 1229010

End: 1230407

Strand: Direct

Name: hlyB [H]

Synonym: ELI_05940

Alternate gene names: 85374015

Gene position: 1229010-1230407 (Clockwise)

Preceding gene: 85374012

Following gene: 85374016

Centisome position: 40.26

GC content: 61.66

Gene sequence:

>1398_bases
ATGGAACATAGCAAGATTATCGCCGCCGACCAGTCCGCATTGGAGCTCATTCCGGGCAAATGCGGCGATGTCACGGTGGG
ATGCACCGACGTCGCCGGCGTCGTCGAAGCGGTCATAGCCTCGTCCGAAAAATTGCGCGAAGAGCATACCGCGCTGCAGG
GTACGATCTCCGACCTCGAGGCCGACCAGGCGAAAGTCAGCGAAGCCAGCGACGAAGCGCGGTTGCTGTCCGAGCGCGCC
ATTGCCCGATTGGGCGACGGTAACGCGCTGATCCGCTCGTCACTGTCGCAGATCACGGAATTGCTCGAACTGGTCGATAC
TCTGACCAAGCATGTTACCGGCTTTGCTTCGGCAATGGACCAGGTGAAGCGCAGCTCGCAGCATATCGACGACATTGCCG
AGACCACCAACATCCTTGCGCTCAATGCCACCATCGAAGCGATGCGGGCAGGGGAGGCCGGTCGCGCGTTTGCCGTGGTC
GCCGACGAAGTGAAGAGCCTTGCCGGGGCGACCCGCAAGGCCACCGAGGAAATCTCCAGCACGATCGACACGCTCGAAGG
CGAAGCCAAGGCGGTGATCGGCAAGATCGAGGGCGGAGCCAAGGCTTCGAGCGAGGCCAAGACCTCGGTCGCCAAGATCG
AAGAGACCATCAGCGGCGTTTCCGACCTGGTCGAGGAAGTCGATCGCCAGAACGACCAGATCGCCCGCGCCACCAACACG
ATCAGCGGTCATGTTTCGAAAGTGCAGGGCGTCCTCACCGGCTTCGACAGCGCCGCGATCGAGAACGAGCAGAAGCTCCA
AAGTGCGCACAGCCGGATGGAAGCGCTGGAACTCACCGCCAGCGAAATGTTCGACAGCATCGTCAAGAGCGGCCTCTCGC
CCAAGGACAGCGAAATGGTGGTCCAGGCACAAGACCATGCCGCGCAACTGGCAGAGGTCGCCGAAGCGGCGATTGCTGTA
GGCGAGATCACGATGGAAGAGCTGTTCGACACACATTATCGCCCGGTCGACGGCAGCAACCCGCCACGCTATCGTTCGAA
CGCGAGCGACTGGGCCGACAGGAACTGGCGCCCGATCATTGATGCGATGGTGGCGAGGGGCGGCGCGATCATGATGTGCT
CGCCCGCCGATATGAACGGCTTTCTGCCGACCCACGTGACCGACCGCTCCCGCCAGCCTACCGGTGATCTCGCGCACGAC
ACGAAATACTGCCGCAACGGTCGTATCTTGCTCGGGCCGATCGATCGCAAGGCAAAACAGAGCAGCGCGCCCTACATGAT
GGCGGTCTATCGCCAGGAAGGCGATGGCAAGCAGTACAATGTGGTGCGCAATGTCTATGTCCCGCTCTACATCAACGGTC
GACGCTGGGGTGACAGCGAGCTCGCCTACAGGTTCTGA

Upstream 100 bases:

>100_bases
AATTGAAAAACATGCGAAAAAGCCTCTTCGGGGACGGAAATCTTTACGCGGCGGTAACCATGCCGCGCCTAGGCATTTCC
CCGCACACACGGGGTACGCA

Downstream 100 bases:

>100_bases
ACTGTTCCGCAGCGGAGCAGGGTGACAAGCGACACCTTGCCGCGCGTGCGGCGCCCATCTACCTCGTTAGCCAAATTTGC
TAACGGAGGCGCCCGGTGCG

Product: putative chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MEHSKIIAADQSALELIPGKCGDVTVGCTDVAGVVEAVIASSEKLREEHTALQGTISDLEADQAKVSEASDEARLLSERA
IARLGDGNALIRSSLSQITELLELVDTLTKHVTGFASAMDQVKRSSQHIDDIAETTNILALNATIEAMRAGEAGRAFAVV
ADEVKSLAGATRKATEEISSTIDTLEGEAKAVIGKIEGGAKASSEAKTSVAKIEETISGVSDLVEEVDRQNDQIARATNT
ISGHVSKVQGVLTGFDSAAIENEQKLQSAHSRMEALELTASEMFDSIVKSGLSPKDSEMVVQAQDHAAQLAEVAEAAIAV
GEITMEELFDTHYRPVDGSNPPRYRSNASDWADRNWRPIIDAMVARGGAIMMCSPADMNGFLPTHVTDRSRQPTGDLAHD
TKYCRNGRILLGPIDRKAKQSSAPYMMAVYRQEGDGKQYNVVRNVYVPLYINGRRWGDSELAYRF

Sequences:

>Translated_465_residues
MEHSKIIAADQSALELIPGKCGDVTVGCTDVAGVVEAVIASSEKLREEHTALQGTISDLEADQAKVSEASDEARLLSERA
IARLGDGNALIRSSLSQITELLELVDTLTKHVTGFASAMDQVKRSSQHIDDIAETTNILALNATIEAMRAGEAGRAFAVV
ADEVKSLAGATRKATEEISSTIDTLEGEAKAVIGKIEGGAKASSEAKTSVAKIEETISGVSDLVEEVDRQNDQIARATNT
ISGHVSKVQGVLTGFDSAAIENEQKLQSAHSRMEALELTASEMFDSIVKSGLSPKDSEMVVQAQDHAAQLAEVAEAAIAV
GEITMEELFDTHYRPVDGSNPPRYRSNASDWADRNWRPIIDAMVARGGAIMMCSPADMNGFLPTHVTDRSRQPTGDLAHD
TKYCRNGRILLGPIDRKAKQSSAPYMMAVYRQEGDGKQYNVVRNVYVPLYINGRRWGDSELAYRF
>Mature_465_residues
MEHSKIIAADQSALELIPGKCGDVTVGCTDVAGVVEAVIASSEKLREEHTALQGTISDLEADQAKVSEASDEARLLSERA
IARLGDGNALIRSSLSQITELLELVDTLTKHVTGFASAMDQVKRSSQHIDDIAETTNILALNATIEAMRAGEAGRAFAVV
ADEVKSLAGATRKATEEISSTIDTLEGEAKAVIGKIEGGAKASSEAKTSVAKIEETISGVSDLVEEVDRQNDQIARATNT
ISGHVSKVQGVLTGFDSAAIENEQKLQSAHSRMEALELTASEMFDSIVKSGLSPKDSEMVVQAQDHAAQLAEVAEAAIAV
GEITMEELFDTHYRPVDGSNPPRYRSNASDWADRNWRPIIDAMVARGGAIMMCSPADMNGFLPTHVTDRSRQPTGDLAHD
TKYCRNGRILLGPIDRKAKQSSAPYMMAVYRQEGDGKQYNVVRNVYVPLYINGRRWGDSELAYRF

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=254, Percent_Identity=28.3464566929134, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367378, Length=146, Percent_Identity=35.6164383561644, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788195, Length=210, Percent_Identity=29.0476190476191, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787690, Length=213, Percent_Identity=28.169014084507, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789453, Length=125, Percent_Identity=34.4, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 50108; Mature: 50108

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSKIIAADQSALELIPGKCGDVTVGCTDVAGVVEAVIASSEKLREEHTALQGTISDLE
CCCCCEEECCCHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADQAKVSEASDEARLLSERAIARLGDGNALIRSSLSQITELLELVDTLTKHVTGFASAMD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKRSSQHIDDIAETTNILALNATIEAMRAGEAGRAFAVVADEVKSLAGATRKATEEISS
HHHHHHHHHHHHHHHHCEEEEHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
TIDTLEGEAKAVIGKIEGGAKASSEAKTSVAKIEETISGVSDLVEEVDRQNDQIARATNT
HHHHHCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISGHVSKVQGVLTGFDSAAIENEQKLQSAHSRMEALELTASEMFDSIVKSGLSPKDSEMV
HHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VQAQDHAAQLAEVAEAAIAVGEITMEELFDTHYRPVDGSNPPRYRSNASDWADRNWRPII
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
DAMVARGGAIMMCSPADMNGFLPTHVTDRSRQPTGDLAHDTKYCRNGRILLGPIDRKAKQ
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
SSAPYMMAVYRQEGDGKQYNVVRNVYVPLYINGRRWGDSELAYRF
CCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCEECCCCCCCCC
>Mature Secondary Structure
MEHSKIIAADQSALELIPGKCGDVTVGCTDVAGVVEAVIASSEKLREEHTALQGTISDLE
CCCCCEEECCCHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADQAKVSEASDEARLLSERAIARLGDGNALIRSSLSQITELLELVDTLTKHVTGFASAMD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVKRSSQHIDDIAETTNILALNATIEAMRAGEAGRAFAVVADEVKSLAGATRKATEEISS
HHHHHHHHHHHHHHHHCEEEEHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
TIDTLEGEAKAVIGKIEGGAKASSEAKTSVAKIEETISGVSDLVEEVDRQNDQIARATNT
HHHHHCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISGHVSKVQGVLTGFDSAAIENEQKLQSAHSRMEALELTASEMFDSIVKSGLSPKDSEMV
HHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VQAQDHAAQLAEVAEAAIAVGEITMEELFDTHYRPVDGSNPPRYRSNASDWADRNWRPII
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
DAMVARGGAIMMCSPADMNGFLPTHVTDRSRQPTGDLAHDTKYCRNGRILLGPIDRKAKQ
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
SSAPYMMAVYRQEGDGKQYNVVRNVYVPLYINGRRWGDSELAYRF
CCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]