Click here to switch to the map view.

The map label for this gene is ywaD [H]

Identifier: 85373436

GI number: 85373436

Start: 640792

End: 642171

Strand: Direct

Name: ywaD [H]

Synonym: ELI_03045

Alternate gene names: 85373436

Gene position: 640792-642171 (Clockwise)

Preceding gene: 85373434

Following gene: 85373437

Centisome position: 20.99

GC content: 65.72

Gene sequence:

>1380_bases
ATGAAGAAACTCGTCACTGCGCTCGCTTGCGTCGCCTTCACCTGTCCGGCTGTCGCCAACCCCGGTCCCCCGCCGACCCT
CGAAGCTCGCGCCGACCTGGCGCTTGAGGCCGACACGATGGCCTGGGGTTTCGTCGAAGGGATCACCACCGAAGTGGGCC
CCCGGCAGGCCGGCACAGAGGCGGAGAAGCGCGGCCGCGACTGGGCGATGCAATGGCTGCGCAACGCCGGCTTCGAAAAC
GTCGCCGACGAGCCGTTCGACATGCAAACCTGGGTGCCGGGCAGTGTGCACAAGGCCGAAGTGGTCAACCCCTATCCCCA
GCCGCTCGTGGTCCAGCCGCTCGGCGGCAGCGCTTCTACCGGCCCGGAAGGAGTCACGGCCGAGGTCATTTACTTCCCGT
CCATAGCCGATCTGCAGGCTGCACCCGACGGAAGCCTTGCGGGCAAGATCGCATTCGTCAGCCACGCGATGACTCCGACT
CAGGACGGATCGCATTACGGATATTTCGGCGCGGCGCGGTTCGTCGGACCTGGGCTGGCGGCGCAGAAGGGCGCGGTCGC
CATCGTCATCAAGTCGATCGGCACCGATTATCACCGCAATCCCCACACCGGCGTCATCCGCTTCCCCGAAGGCGTTGCGC
CGATCCCCGCCGGCGCGCTGAGCCTGCCCGATGCAGCCAATCTCGAGCGCATGTTCCAGCGTGCATCCGGCGCGCCGATC
ACGCTCAAGCTCACGCTGACGCCGCGCAGTCTCGGCACCACGACCAGCGGCAATGTAGTCGGTGAAATCGTCGGGCGTGA
CCCATCGCTGCCTCCCGTGCTGGTCGCGTGCCATATCGACAGCTGGTGGAACGCGCCGGGCGCGTTCGACGACGGTGCGG
GATGCGGTATTGTCGCGGCAGCCGCGCGACTGGCCGGTCTTGGCGACCAGCGTCTGCGCACCATTCGCGTACTGATGGCG
GGTGCCGAGGAAGTCGGCCTGTTCGGCTCGGTCGCCTATTCCGAAGCGCATATCGACGAGCCTATCGCCGTCGCGCTGGA
GAGCGATTTCGGCGCGGATCGGATCTGGCGCTTCGAAAGCAACTTTCGCGAGAGCAACCCCGACCTGCACAATCGCCTCG
CCGCCTCGGTCGCGCGCTTCGGAGTATCGAACTCGACCATCGTCGCGAGCGGCGGGGCCGACATCAATATCGCTCGTGAC
CAGGGCACCGCGATCATCGACCTGCAACAGGACGGCACGCGCTATTTCGACCTGCACCATACGCCGGACGATACGCTCGA
CAAAATCGACAAGGCGCAGCTGCGCCAGAACGTTGCGGTGTGGACCCAGGTCGTCGGCATCCTCGCCAACGAGCCGAAAA
ATATCCAGACCGGGCAATAG

Upstream 100 bases:

>100_bases
TTTGAAAATGCGTTCCAATATTGCGTCGATTCAGCGGCGAAGCGAATGTCTCGAGCGGCGGTATGGACTTGCATCGGCAA
GCCAGATAGCAGCGCTGGTC

Downstream 100 bases:

>100_bases
GTTGGCGAAAAAATGCGCCTGACTGGGGATTAAACCCGTCGCTGCATCCGTTTTCCCGACGACCGGCCCCGTAGCGGGCC
GGGCGGAAACGAATGGAGAC

Product: peptidase, M28 family protein

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKKLVTALACVAFTCPAVANPGPPPTLEARADLALEADTMAWGFVEGITTEVGPRQAGTEAEKRGRDWAMQWLRNAGFEN
VADEPFDMQTWVPGSVHKAEVVNPYPQPLVVQPLGGSASTGPEGVTAEVIYFPSIADLQAAPDGSLAGKIAFVSHAMTPT
QDGSHYGYFGAARFVGPGLAAQKGAVAIVIKSIGTDYHRNPHTGVIRFPEGVAPIPAGALSLPDAANLERMFQRASGAPI
TLKLTLTPRSLGTTTSGNVVGEIVGRDPSLPPVLVACHIDSWWNAPGAFDDGAGCGIVAAAARLAGLGDQRLRTIRVLMA
GAEEVGLFGSVAYSEAHIDEPIAVALESDFGADRIWRFESNFRESNPDLHNRLAASVARFGVSNSTIVASGGADINIARD
QGTAIIDLQQDGTRYFDLHHTPDDTLDKIDKAQLRQNVAVWTQVVGILANEPKNIQTGQ

Sequences:

>Translated_459_residues
MKKLVTALACVAFTCPAVANPGPPPTLEARADLALEADTMAWGFVEGITTEVGPRQAGTEAEKRGRDWAMQWLRNAGFEN
VADEPFDMQTWVPGSVHKAEVVNPYPQPLVVQPLGGSASTGPEGVTAEVIYFPSIADLQAAPDGSLAGKIAFVSHAMTPT
QDGSHYGYFGAARFVGPGLAAQKGAVAIVIKSIGTDYHRNPHTGVIRFPEGVAPIPAGALSLPDAANLERMFQRASGAPI
TLKLTLTPRSLGTTTSGNVVGEIVGRDPSLPPVLVACHIDSWWNAPGAFDDGAGCGIVAAAARLAGLGDQRLRTIRVLMA
GAEEVGLFGSVAYSEAHIDEPIAVALESDFGADRIWRFESNFRESNPDLHNRLAASVARFGVSNSTIVASGGADINIARD
QGTAIIDLQQDGTRYFDLHHTPDDTLDKIDKAQLRQNVAVWTQVVGILANEPKNIQTGQ
>Mature_459_residues
MKKLVTALACVAFTCPAVANPGPPPTLEARADLALEADTMAWGFVEGITTEVGPRQAGTEAEKRGRDWAMQWLRNAGFEN
VADEPFDMQTWVPGSVHKAEVVNPYPQPLVVQPLGGSASTGPEGVTAEVIYFPSIADLQAAPDGSLAGKIAFVSHAMTPT
QDGSHYGYFGAARFVGPGLAAQKGAVAIVIKSIGTDYHRNPHTGVIRFPEGVAPIPAGALSLPDAANLERMFQRASGAPI
TLKLTLTPRSLGTTTSGNVVGEIVGRDPSLPPVLVACHIDSWWNAPGAFDDGAGCGIVAAAARLAGLGDQRLRTIRVLMA
GAEEVGLFGSVAYSEAHIDEPIAVALESDFGADRIWRFESNFRESNPDLHNRLAASVARFGVSNSTIVASGGADINIARD
QGTAIIDLQQDGTRYFDLHHTPDDTLDKIDKAQLRQNVAVWTQVVGILANEPKNIQTGQ

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Homo sapiens, GI7706387, Length=387, Percent_Identity=29.1989664082687, Blast_Score=138, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 48483; Mature: 48483

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVTALACVAFTCPAVANPGPPPTLEARADLALEADTMAWGFVEGITTEVGPRQAGTE
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCH
AEKRGRDWAMQWLRNAGFENVADEPFDMQTWVPGSVHKAEVVNPYPQPLVVQPLGGSAST
HHHCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCCCEEEEECCCCCCC
GPEGVTAEVIYFPSIADLQAAPDGSLAGKIAFVSHAMTPTQDGSHYGYFGAARFVGPGLA
CCCCCEEEEEECCCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHCCCCCC
AQKGAVAIVIKSIGTDYHRNPHTGVIRFPEGVAPIPAGALSLPDAANLERMFQRASGAPI
CCCCCEEEEEEHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
TLKLTLTPRSLGTTTSGNVVGEIVGRDPSLPPVLVACHIDSWWNAPGAFDDGAGCGIVAA
EEEEEECCHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
AARLAGLGDQRLRTIRVLMAGAEEVGLFGSVAYSEAHIDEPIAVALESDFGADRIWRFES
HHHHHCCCHHHHHHHHHHHHCCHHHCCEEEEHHHHHCCCCCEEEEEECCCCCCCEEEEHH
NFRESNPDLHNRLAASVARFGVSNSTIVASGGADINIARDQGTAIIDLQQDGTRYFDLHH
HHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCEEEEEECCCCEEEEEEC
TPDDTLDKIDKAQLRQNVAVWTQVVGILANEPKNIQTGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKLVTALACVAFTCPAVANPGPPPTLEARADLALEADTMAWGFVEGITTEVGPRQAGTE
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCH
AEKRGRDWAMQWLRNAGFENVADEPFDMQTWVPGSVHKAEVVNPYPQPLVVQPLGGSAST
HHHCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCCCEEEEECCCCCCC
GPEGVTAEVIYFPSIADLQAAPDGSLAGKIAFVSHAMTPTQDGSHYGYFGAARFVGPGLA
CCCCCEEEEEECCCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHCCCCCC
AQKGAVAIVIKSIGTDYHRNPHTGVIRFPEGVAPIPAGALSLPDAANLERMFQRASGAPI
CCCCCEEEEEEHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCE
TLKLTLTPRSLGTTTSGNVVGEIVGRDPSLPPVLVACHIDSWWNAPGAFDDGAGCGIVAA
EEEEEECCHHCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHH
AARLAGLGDQRLRTIRVLMAGAEEVGLFGSVAYSEAHIDEPIAVALESDFGADRIWRFES
HHHHHCCCHHHHHHHHHHHHCCHHHCCEEEEHHHHHCCCCCEEEEEECCCCCCCEEEEHH
NFRESNPDLHNRLAASVARFGVSNSTIVASGGADINIARDQGTAIIDLQQDGTRYFDLHH
HHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCEEEEEECCCCEEEEEEC
TPDDTLDKIDKAQLRQNVAVWTQVVGILANEPKNIQTGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]