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The map label for this gene is tlpA [H]

Identifier: 85373235

GI number: 85373235

Start: 453322

End: 453876

Strand: Direct

Name: tlpA [H]

Synonym: ELI_02040

Alternate gene names: 85373235

Gene position: 453322-453876 (Clockwise)

Preceding gene: 85373230

Following gene: 85373236

Centisome position: 14.85

GC content: 63.96

Gene sequence:

>555_bases
GTGTCGCTCACGCTTGCAATCGTCCTTCTTGCGCTCGCCGGGTGCGATAGGGCCGCGCCCGACCCCGCGCAAGGCGAGGG
CGCATTGGGGGCGGAGAAGGCCAGCTTGGCCGGCGAAGTCGATCGCAGTCGCGCGGGCGAACTGATGCCGGCAGAGACGG
TCCGTCTGCCCGATGGCACGCAGCTCAATCTCGGCGCGCTGCAGGGCCAGCCGGTACTGCTCAACCTGTGGGCAACGTGG
TGTGCGCCGTGCAAGAAGGAGATGCCGCTGCTCGATGAATTGGCTCTGGAGCGCGACGGTGAGCTGCGGGTCCTGACCGT
CAGCCAGGATTTACAAGGTGCAGAGAAAGTCTTGCCCTATTTCGAACAAGCGGGTTTCCAAGCGCTCGAGCCGTGGCTCG
ACCCGCACAATGGGCTGGGCCAGCACTACGACGCGGGGCTGCCGATGACGGTGCTCTATGACGCGAATGGGCAAGAGGTG
TGGCGCATCGCGGGAGATTACGACTGGTCGAGTGCCGAGGCGGCTGGATTGATTGATGAGGGTATAGGTACATAA

Upstream 100 bases:

>100_bases
CTTGTCGAACGGGATAGAAGCGTTGATTTCGCGCATGATCGCACTAGGTCCTTCAGCGAACCTGCCGCCCCACATCTGGT
TGGAGCCTTTCGTGTCCCGA

Downstream 100 bases:

>100_bases
TTGTACGATGAGAAAGCACCTAGATTTCGTAGGTAACTCGCGAGGCGATCAATTGCTGGAATTTTTCCTGACACAGCCAG
CGTAGTGTATATTTGGCACA

Product: thiol:disulfide interchange protein, putative

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSLTLAIVLLALAGCDRAAPDPAQGEGALGAEKASLAGEVDRSRAGELMPAETVRLPDGTQLNLGALQGQPVLLNLWATW
CAPCKKEMPLLDELALERDGELRVLTVSQDLQGAEKVLPYFEQAGFQALEPWLDPHNGLGQHYDAGLPMTVLYDANGQEV
WRIAGDYDWSSAEAAGLIDEGIGT

Sequences:

>Translated_184_residues
MSLTLAIVLLALAGCDRAAPDPAQGEGALGAEKASLAGEVDRSRAGELMPAETVRLPDGTQLNLGALQGQPVLLNLWATW
CAPCKKEMPLLDELALERDGELRVLTVSQDLQGAEKVLPYFEQAGFQALEPWLDPHNGLGQHYDAGLPMTVLYDANGQEV
WRIAGDYDWSSAEAAGLIDEGIGT
>Mature_183_residues
SLTLAIVLLALAGCDRAAPDPAQGEGALGAEKASLAGEVDRSRAGELMPAETVRLPDGTQLNLGALQGQPVLLNLWATWC
APCKKEMPLLDELALERDGELRVLTVSQDLQGAEKVLPYFEQAGFQALEPWLDPHNGLGQHYDAGLPMTVLYDANGQEVW
RIAGDYDWSSAEAAGLIDEGIGT

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19624; Mature: 19493

Theoretical pI: Translated: 3.96; Mature: 3.96

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTLAIVLLALAGCDRAAPDPAQGEGALGAEKASLAGEVDRSRAGELMPAETVRLPDGT
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCCEEECCCCC
QLNLGALQGQPVLLNLWATWCAPCKKEMPLLDELALERDGELRVLTVSQDLQGAEKVLPY
EEEEECCCCCCEEEEHHHHHHCCHHCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
FEQAGFQALEPWLDPHNGLGQHYDAGLPMTVLYDANGQEVWRIAGDYDWSSAEAAGLIDE
HHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHC
GIGT
CCCC
>Mature Secondary Structure 
SLTLAIVLLALAGCDRAAPDPAQGEGALGAEKASLAGEVDRSRAGELMPAETVRLPDGT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCCCCCCEEECCCCC
QLNLGALQGQPVLLNLWATWCAPCKKEMPLLDELALERDGELRVLTVSQDLQGAEKVLPY
EEEEECCCCCCEEEEHHHHHHCCHHCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHH
FEQAGFQALEPWLDPHNGLGQHYDAGLPMTVLYDANGQEVWRIAGDYDWSSAEAAGLIDE
HHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHC
GIGT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]