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The map label for this gene is argS

Identifier: 85373141

GI number: 85373141

Start: 357435

End: 359180

Strand: Direct

Name: argS

Synonym: ELI_01570

Alternate gene names: 85373141

Gene position: 357435-359180 (Clockwise)

Preceding gene: 85373140

Following gene: 85373142

Centisome position: 11.71

GC content: 61.8

Gene sequence:

>1746_bases
ATGTCCGAATTGAACACGATTCACGCCGCCTTCGCTGCGAAGGTCGATGCGGTGCTGTCCGCGCTCGAAGCCGAAGGCAC
GCTGCCTGCCGGTGTCGAGCGCCGCAATGTGACGGTCGAACCGCCGCGCGACCCATCGCACGGAGACCTGGCGACCAACG
CCGCCATGGTGCTGGCCAAACAGGCCGCCACCAATCCGCGCGCGCTCGCGGAAAAGATCGTCGAGCATCTCGAGCGCGAT
CCCGATATCACCGAGACGGCAATTGCCGGGCCCGGCTTCATCAATCTGCGTCTGGCCGACCGCGCGTGGCTGGGCGAACT
CGAAGCGATTGCGGCGTTGGGCGAGGGCTATGGCCGTTCTCAGATGGGCGAGGGCAAGCGGGTCAATGTCGAATATGTTT
CCGCCAATCCGACCGGCCCGATGCACATGGGGCATTGTCGCGGCGCGGTGGTCGGCGATGCCTTGGCGGCGTTGCTGGAA
TATGCCGGACACGAGGTCACGCGCGAATATTATGTCAACGACGCTGGCGGACAAGTCGATACGCTCGCCCGTTCGGCGCA
CTTGCGTTACCGCGAGGCGCTGGGCGAAGATATCGGCGCAATTCCCGGGGGCCTTTACCCTGGAGACTACCTGAAACCGG
TGGGCGAATATCTCGCGCAGGAACTGGGCGATCGCTTCAAGGATGCGCCGGAAGACGAATGGCTGCCGATATTCCGCGCC
GAGGCGGTCGAAAAGATGATGGACGTCATCCGCGCCGACCTCGCGCTTCTGGGCATCCATCACGACCTGTTTTCGTCCGA
GGCGGCGCTGCAGGCAGCGGGCAAGCCCGAGCAGGCCGAGGCGTGGCTGCGCGAGCATGGTCTTGTCTATGACGGCGTGC
TCGAACAGCCCAAGGGCAAGGTGATCGAGGACTGGGAGCCGGTCGAACTGCCGCTGTTCCGTTCGACCAAGTTCGGCGAC
GATCAGGATCGACCGATCAGGAAATCCGACGGCAAATGGACCTATTTCGGGGCCGATCTTGCCTATCACATGCAGAAGGC
GGAAGAAGCCGATGCGCTGATCGACATCTGGGGCGCCGACCATGCGGGCACGGTCAAGCGGATCAAGGCGGCGGTGGCGG
CGCTATCGGAAGGGCAGGGCAAGCCGATTCCCTTCGATGTAAAGCTTGTACAAATGGTGCAACTGATGCGCGCGGGCGAG
CCGGTGAAGATGTCTAAGCGTTCGGGCAATTTCATCACCATCGCCGACATGGTCGAGGAGGTCGGCAAGGATGTCGTTCG
TTTCACCATGCTGACCCGCAAACCCGAAGCGCAGATGGATTTCGATTTCGCCAAGGTAGTGGAAGCGTCCAAGGACAATC
CGGTTTTCTACGTCCAGTATGCCCACGCACGGATCCATTCGACGTTGCGCAAGGCCAGGGCCGAAGGGATCGAGCCTTCG
ACAGAGGCGATCGCACAGCTGGGCGAGGAAGAACTGGGCCTGATCAAACAGGCGGCGCAATTCCCGCGCATCGTCGAAGC
GGCGGCCGCAGCGCGCGAACCACATCGGATCGCCTTCTTCCTTTATGATCTCGCGAGCGCGTTCCATTCGTTTTACAATC
TCGGGAACGACAATCCGTCGAAACGCGTCATTCTGGCACAGGATCCGGCGCTTTCCGCAGCAAGGCTTTTCCTGATCGAC
ACAATCGGGCAAGTTATCCGCAATGGGCTAACCCTGCTCGGGGTCGAGGCCGTGGAGGAGATGTGA

Upstream 100 bases:

>100_bases
TTCCAGCTGAGCGAGAGCCAGCTGGCATACAACGCGACCCGCTAAACGCCCCGCCAATCTCGCTTTGCGATAGGGCGCGT
TTCCGGCTAACCGCGCCCGC

Downstream 100 bases:

>100_bases
GATGATCGCTGAGAGCGGTGACAGGGACAAGCACGACGAGCCGATCGAGCAGTTCGAAGACGAGCAGGAAACCGACGAGC
TCGACCTCGACGACGATGAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSELNTIHAAFAAKVDAVLSALEAEGTLPAGVERRNVTVEPPRDPSHGDLATNAAMVLAKQAATNPRALAEKIVEHLERD
PDITETAIAGPGFINLRLADRAWLGELEAIAALGEGYGRSQMGEGKRVNVEYVSANPTGPMHMGHCRGAVVGDALAALLE
YAGHEVTREYYVNDAGGQVDTLARSAHLRYREALGEDIGAIPGGLYPGDYLKPVGEYLAQELGDRFKDAPEDEWLPIFRA
EAVEKMMDVIRADLALLGIHHDLFSSEAALQAAGKPEQAEAWLREHGLVYDGVLEQPKGKVIEDWEPVELPLFRSTKFGD
DQDRPIRKSDGKWTYFGADLAYHMQKAEEADALIDIWGADHAGTVKRIKAAVAALSEGQGKPIPFDVKLVQMVQLMRAGE
PVKMSKRSGNFITIADMVEEVGKDVVRFTMLTRKPEAQMDFDFAKVVEASKDNPVFYVQYAHARIHSTLRKARAEGIEPS
TEAIAQLGEEELGLIKQAAQFPRIVEAAAAAREPHRIAFFLYDLASAFHSFYNLGNDNPSKRVILAQDPALSAARLFLID
TIGQVIRNGLTLLGVEAVEEM

Sequences:

>Translated_581_residues
MSELNTIHAAFAAKVDAVLSALEAEGTLPAGVERRNVTVEPPRDPSHGDLATNAAMVLAKQAATNPRALAEKIVEHLERD
PDITETAIAGPGFINLRLADRAWLGELEAIAALGEGYGRSQMGEGKRVNVEYVSANPTGPMHMGHCRGAVVGDALAALLE
YAGHEVTREYYVNDAGGQVDTLARSAHLRYREALGEDIGAIPGGLYPGDYLKPVGEYLAQELGDRFKDAPEDEWLPIFRA
EAVEKMMDVIRADLALLGIHHDLFSSEAALQAAGKPEQAEAWLREHGLVYDGVLEQPKGKVIEDWEPVELPLFRSTKFGD
DQDRPIRKSDGKWTYFGADLAYHMQKAEEADALIDIWGADHAGTVKRIKAAVAALSEGQGKPIPFDVKLVQMVQLMRAGE
PVKMSKRSGNFITIADMVEEVGKDVVRFTMLTRKPEAQMDFDFAKVVEASKDNPVFYVQYAHARIHSTLRKARAEGIEPS
TEAIAQLGEEELGLIKQAAQFPRIVEAAAAAREPHRIAFFLYDLASAFHSFYNLGNDNPSKRVILAQDPALSAARLFLID
TIGQVIRNGLTLLGVEAVEEM
>Mature_580_residues
SELNTIHAAFAAKVDAVLSALEAEGTLPAGVERRNVTVEPPRDPSHGDLATNAAMVLAKQAATNPRALAEKIVEHLERDP
DITETAIAGPGFINLRLADRAWLGELEAIAALGEGYGRSQMGEGKRVNVEYVSANPTGPMHMGHCRGAVVGDALAALLEY
AGHEVTREYYVNDAGGQVDTLARSAHLRYREALGEDIGAIPGGLYPGDYLKPVGEYLAQELGDRFKDAPEDEWLPIFRAE
AVEKMMDVIRADLALLGIHHDLFSSEAALQAAGKPEQAEAWLREHGLVYDGVLEQPKGKVIEDWEPVELPLFRSTKFGDD
QDRPIRKSDGKWTYFGADLAYHMQKAEEADALIDIWGADHAGTVKRIKAAVAALSEGQGKPIPFDVKLVQMVQLMRAGEP
VKMSKRSGNFITIADMVEEVGKDVVRFTMLTRKPEAQMDFDFAKVVEASKDNPVFYVQYAHARIHSTLRKARAEGIEPST
EAIAQLGEEELGLIKQAAQFPRIVEAAAAAREPHRIAFFLYDLASAFHSFYNLGNDNPSKRVILAQDPALSAARLFLIDT
IGQVIRNGLTLLGVEAVEEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=607, Percent_Identity=24.7116968698517, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=26.3431542461005, Blast_Score=125, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320548, Length=624, Percent_Identity=25.4807692307692, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859963, Length=603, Percent_Identity=24.5439469320066, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63505; Mature: 63374

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELNTIHAAFAAKVDAVLSALEAEGTLPAGVERRNVTVEPPRDPSHGDLATNAAMVLAK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
QAATNPRALAEKIVEHLERDPDITETAIAGPGFINLRLADRAWLGELEAIAALGEGYGRS
HHCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCC
QMGEGKRVNVEYVSANPTGPMHMGHCRGAVVGDALAALLEYAGHEVTREYYVNDAGGQVD
CCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHEECCCCCHHH
TLARSAHLRYREALGEDIGAIPGGLYPGDYLKPVGEYLAQELGDRFKDAPEDEWLPIFRA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EAVEKMMDVIRADLALLGIHHDLFSSEAALQAAGKPEQAEAWLREHGLVYDGVLEQPKGK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCEECCHHCCCCCC
VIEDWEPVELPLFRSTKFGDDQDRPIRKSDGKWTYFGADLAYHMQKAEEADALIDIWGAD
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCEEEECCCC
HAGTVKRIKAAVAALSEGQGKPIPFDVKLVQMVQLMRAGEPVKMSKRSGNFITIADMVEE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHH
VGKDVVRFTMLTRKPEAQMDFDFAKVVEASKDNPVFYVQYAHARIHSTLRKARAEGIEPS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCH
TEAIAQLGEEELGLIKQAAQFPRIVEAAAAAREPHRIAFFLYDLASAFHSFYNLGNDNPS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
KRVILAQDPALSAARLFLIDTIGQVIRNGLTLLGVEAVEEM
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHCC
>Mature Secondary Structure 
SELNTIHAAFAAKVDAVLSALEAEGTLPAGVERRNVTVEPPRDPSHGDLATNAAMVLAK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHH
QAATNPRALAEKIVEHLERDPDITETAIAGPGFINLRLADRAWLGELEAIAALGEGYGRS
HHCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCC
QMGEGKRVNVEYVSANPTGPMHMGHCRGAVVGDALAALLEYAGHEVTREYYVNDAGGQVD
CCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHEECCCCCHHH
TLARSAHLRYREALGEDIGAIPGGLYPGDYLKPVGEYLAQELGDRFKDAPEDEWLPIFRA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EAVEKMMDVIRADLALLGIHHDLFSSEAALQAAGKPEQAEAWLREHGLVYDGVLEQPKGK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCEECCHHCCCCCC
VIEDWEPVELPLFRSTKFGDDQDRPIRKSDGKWTYFGADLAYHMQKAEEADALIDIWGAD
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCEEEECCCC
HAGTVKRIKAAVAALSEGQGKPIPFDVKLVQMVQLMRAGEPVKMSKRSGNFITIADMVEE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHH
VGKDVVRFTMLTRKPEAQMDFDFAKVVEASKDNPVFYVQYAHARIHSTLRKARAEGIEPS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCH
TEAIAQLGEEELGLIKQAAQFPRIVEAAAAAREPHRIAFFLYDLASAFHSFYNLGNDNPS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
KRVILAQDPALSAARLFLIDTIGQVIRNGLTLLGVEAVEEM
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA