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The map label for this gene is sugE [H]

Identifier: 84625588

GI number: 84625588

Start: 4430410

End: 4430724

Strand: Reverse

Name: sugE [H]

Synonym: XOO_3931

Alternate gene names: 84625588

Gene position: 4430724-4430410 (Counterclockwise)

Preceding gene: 84625589

Following gene: 84625586

Centisome position: 89.69

GC content: 62.86

Gene sequence:

>315_bases
ATGCTCTGGATCTATCTGCTGCTGGCCGGCCTGTTCGAGATCGGCTTTGCCATGGGACTGAAATACAGCGACGGCTTCAC
CCGACTGTGGCCGACCGTGCTGACCATTGGTCTGGCCGGCACCAGCCTCTGGTTTCTGACGCAGGCGCTGAAGACCATTC
CGGTCGGCACCGGCTACGCGATCTGGACCGGCATCGGCGCCCTGGGCGTGACCATCGCCGGCATCGCGCTATTCGGCGAC
AGCGCGTCGTGGCCGCGATTGGCGTGCATTGGTTTGATCGTGTCTGGCGTGATCGGGTTGAAGTTCGTCTCGTAG

Upstream 100 bases:

>100_bases
GGCCCGCCACGCGATGACTTCGCGTTCCACAGCCGACGGCGGCCCAGTGTGCAAACACTGGGTCGCTTTTTTTTACCCCT
TTTTTGCGAGGAATACTGCA

Downstream 100 bases:

>100_bases
TTAGCTCCGCTTTGCGGTGCCGCCCTCCAAGTTTGCTGCGCAAACCTTTAGCCCCGACGCAGTGACGTCCTATCCCCACG
CCTTCGGCGCGCCCCCTTAA

Product: SugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MLWIYLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGTSLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGD
SASWPRLACIGLIVSGVIGLKFVS

Sequences:

>Translated_104_residues
MLWIYLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGTSLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGD
SASWPRLACIGLIVSGVIGLKFVS
>Mature_104_residues
MLWIYLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGTSLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGD
SASWPRLACIGLIVSGVIGLKFVS

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=53.921568627451, Blast_Score=105, Evalue=7e-25,
Organism=Escherichia coli, GI1786755, Length=102, Percent_Identity=39.2156862745098, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10982; Mature: 10982

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIYLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGTSLWFLTQALKTIPVGTGYA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
IWTGIGALGVTIAGIALFGDSASWPRLACIGLIVSGVIGLKFVS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLWIYLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGTSLWFLTQALKTIPVGTGYA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
IWTGIGALGVTIAGIALFGDSASWPRLACIGLIVSGVIGLKFVS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA