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The map label for this gene is rppH [H]

Identifier: 84625584

GI number: 84625584

Start: 4427300

End: 4427917

Strand: Reverse

Name: rppH [H]

Synonym: XOO_3927

Alternate gene names: 84625584

Gene position: 4427917-4427300 (Counterclockwise)

Preceding gene: 84625585

Following gene: 84625583

Centisome position: 89.63

GC content: 64.56

Gene sequence:

>618_bases
GTGATCGATCCGGACGGTTTCCGGCCAAACGTTGGCATCGTGCTGATGCGGCAGGACGGTCAGGTGTTCTGGGCACGACG
TGTGCGCAGGGACGGTTGGCAGTTCCCGCAAGGTGGCATGAACACCGACGAGACTCCCGTTGAAGCCATGTACCGCGAGT
TGCGCGAAGAAACCGGGTTGTTGCCCGAGCATGTGGAATTGCTCGGCGCCACGCCCGGGTGGCTACGCTATCGCTTGCCC
AGCCGCGCGGTGCGCCGCAATGAGCGGCAGGTGTGTATCGGGCAGAAGCAGGTCTGGTTCCTGCTGCGTTTCACCGGCGA
TGAATCCCACCTCAAGCTCGACCACACCGACACTCCGGAGTTCGATCATTGGCGCTGGGTGGATTTCTGGTATCCAGTCG
AGCACGTGGTGATGTTCAAGCGCGGCGTCTACGCCCGCGCGCTGCGTCATCTGGCGCCGATTGCGCAGAATCTGGCCGGC
CCGGCGGCGGTCGGTGCGATGCCCGAACGTGCGCTGGAGGCGTGGTTGCCGGGCAGCAGCGCGGCTGGGCACGACAGCCC
ACGCAAGCGGCCACGCAAGCGCAGCGGGGCTCGGCCCATGCGGATTAATAATGATTAA

Upstream 100 bases:

>100_bases
CACGATGTGCTGCGTTGTTGTCAAGCATTTCGTTTTCAGCTTGTGAGCCGGGCGTCGCCGTGGCAGAGTCGGGGGTAGTA
GATTTTCAGGAGTCCGCATC

Downstream 100 bases:

>100_bases
CGTATGGAATTGACACCTATTCTCGTTTGCGATGCAATTGGTTCCGGTCCTTTCCGGATCGCCAACACCTGACCGATACC
GTGTACGTCTGCATCTGCAA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLP
SRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAG
PAAVGAMPERALEAWLPGSSAAGHDSPRKRPRKRSGARPMRINND

Sequences:

>Translated_205_residues
MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLP
SRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAG
PAAVGAMPERALEAWLPGSSAAGHDSPRKRPRKRSGARPMRINND
>Mature_205_residues
MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLP
SRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAG
PAAVGAMPERALEAWLPGSSAAGHDSPRKRPRKRSGARPMRINND

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=158, Percent_Identity=53.1645569620253, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 23729; Mature: 23729

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGL
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVELLGATPGWLRYRLPSRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPE
CHHHHHHHCCCCCCEEEECCHHHHHCCCCCEEECCCEEEEEEEEECCCCEEEECCCCCCC
FDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAGPAAVGAMPERALEAWLPGSS
CCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCC
AAGHDSPRKRPRKRSGARPMRINND
CCCCCCHHHCCHHHCCCCCEEECCC
>Mature Secondary Structure
MIDPDGFRPNVGIVLMRQDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGL
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LPEHVELLGATPGWLRYRLPSRAVRRNERQVCIGQKQVWFLLRFTGDESHLKLDHTDTPE
CHHHHHHHCCCCCCEEEECCHHHHHCCCCCEEECCCEEEEEEEEECCCCEEEECCCCCCC
FDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPIAQNLAGPAAVGAMPERALEAWLPGSS
CCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCC
AAGHDSPRKRPRKRSGARPMRINND
CCCCCCHHHCCHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]