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The map label for this gene is gcp [H]

Identifier: 84625558

GI number: 84625558

Start: 4400140

End: 4401204

Strand: Reverse

Name: gcp [H]

Synonym: XOO_3901

Alternate gene names: 84625558

Gene position: 4401204-4400140 (Counterclockwise)

Preceding gene: 84625565

Following gene: 84625557

Centisome position: 89.09

GC content: 68.92

Gene sequence:

>1065_bases
GTGAAAGTTCTTGGGATCGAATCATCGTGCGATGAGACCGGTGTGGCGGTCTACGACACCGCGCTGTCCGGTGTGCCGGC
GCTGCGCGCCCACGCGGTGTACAGCCAGATTGCGTTGCATGCCGAATACGGCGGCGTGGTGCCGGAGCTGGCCAGCCGTG
ACCACGTGCGCAAGCTGCTGCCACTGATCCGTCAGACCCTGGGCGAGGCCGGTGTGGGCATCGACGAACTCGATGGCGTG
GCCTACACCGCCGGCCCGGGCCTGGTTGGTGCCTTGCTGGTCGGTGCCGGGGTGGCGCGCTCGCTGGCCTGGGCACTGGA
TGTGCCGGCGATTGGCGTGCACCACATGGAAGGCCACTTGCTGGCGCCGTTGATGGAAGACGACCCGCCGGAGCCGCCGT
TCGTGGCCTTGCTGGTCTCGGGCGGGCATACCCAATTGGTGTCGGTGAAGGCGCTGGGCAGCTATGAAGTATTGGGCGAG
ACCCTGGATGACGCGGCCGGCGAGGCCTTCGACAAGACCGCCAAAATGATGGGCCTGCCATATCCGGGCGGCCCGCAGCT
GGCGGCGCTGGCCGAAACCGGCACGCCGGGGCGTTACAGGTTCGCGCGGCCGATGACCGACCGACCCGGCCTGGATTTCA
GTTTCAGCGGGCTCAAGACCCAGGTGCTGCTGGCCTGGCGGTCCAGCGACCAGTCCGACACCACCCGGGCGGACATCGCG
CGCGGCTTCGAGGACGCGGTGGTCGACACCTTGGTCATCAAATGCCTGCGCGCGCTGGATGCGGCCGAGTGCAATACGTT
GGTGGTGGCTGGCGGGGTGGGTGTGAACAAGCGCTTGCGCGCGCGCCTGCAGGAGGCTGCGCAGCGCCGCGGCGGCCGGG
TCTGCTTCCCACGCCCGGCCTTGTGCACCGACAACGGCGCAATGATCGCCTTCGCTGGCGCGCTGCGGCTGCAAGCCGGC
GAGCGCGCCGATGCGGCGGTGCATGTGACGCCGCGCTGGGATATGGCTGCGCTGCCGCCATTGGCGGCGGGGCGGGATTC
GGGAGTGGAGATTCGGGAGTGGTAG

Upstream 100 bases:

>100_bases
ACGGCAACGATCACGGGGCGGCGCAGCATATCGCCATCGGCCGATCTGCGCAGCCCAAAAACTGCGAAAATAGCCACCTG
TCCATGCTTGCCGAGCTGCC

Downstream 100 bases:

>100_bases
CCCGGTTTCTTGTTGGCTCTGCTCCTGATTTGCCTGCTCTTGCTAATCCCGACTCCCCAATCCCAAATCCCGGCTTCCAT
GGATAAAGTGTTTATTGAAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGVGIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPEPPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYRFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLVIKCLRALDAAECNTLVVAGGVGVNKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
ERADAAVHVTPRWDMAALPPLAAGRDSGVEIREW

Sequences:

>Translated_354_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGVGIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPEPPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYRFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLVIKCLRALDAAECNTLVVAGGVGVNKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
ERADAAVHVTPRWDMAALPPLAAGRDSGVEIREW
>Mature_354_residues
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGVGIDELDGV
AYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPEPPFVALLVSGGHTQLVSVKALGSYEVLGE
TLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYRFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
RGFEDAVVDTLVIKCLRALDAAECNTLVVAGGVGVNKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAG
ERADAAVHVTPRWDMAALPPLAAGRDSGVEIREW

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=33.1378299120235, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI8923380, Length=297, Percent_Identity=31.6498316498317, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=65.7817109144543, Blast_Score=447, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=29.5180722891566, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=32.6283987915408, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6320099, Length=343, Percent_Identity=32.3615160349854, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=296, Percent_Identity=29.3918918918919, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129063, Length=344, Percent_Identity=34.8837209302326, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21357207, Length=346, Percent_Identity=29.7687861271676, Blast_Score=138, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37200; Mature: 37200

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGVGIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPEPPFVALLVSGGHTQLVSVKALGSYEVLGETLDDAAGEAFDKTAKMMGLP
ECCHHCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYRFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVDTLVIKCLRALDAAECNTLVVAGGVGVNKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGERADAAVHVTPRWDMAALPPLAAGRDSGVEIREW
EECCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLL
CEEECCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHH
PLIRQTLGEAGVGIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHL
HHHHHHHHHCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCE
LAPLMEDDPPEPPFVALLVSGGHTQLVSVKALGSYEVLGETLDDAAGEAFDKTAKMMGLP
ECCHHCCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
YPGGPQLAALAETGTPGRYRFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIA
CCCCCCEEEEECCCCCCCEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHH
RGFEDAVVDTLVIKCLRALDAAECNTLVVAGGVGVNKRLRARLQEAAQRRGGRVCFPRPA
HCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCC
LCTDNGAMIAFAGALRLQAGERADAAVHVTPRWDMAALPPLAAGRDSGVEIREW
EECCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA