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The map label for this gene is yuxL [H]

Identifier: 84625474

GI number: 84625474

Start: 4320824

End: 4322770

Strand: Reverse

Name: yuxL [H]

Synonym: XOO_3817

Alternate gene names: 84625474

Gene position: 4322770-4320824 (Counterclockwise)

Preceding gene: 84625477

Following gene: 84625472

Centisome position: 87.5

GC content: 63.02

Gene sequence:

>1947_bases
ATGGCGGTTGGGTGTGTATGCGCGTTACTGGCGGCGATGCCGGGGCAGGCGCAAGAGGCGCTGGATCTGACCCCGTATCT
CAAGCGCGACCAGATCGAGCGGATCAAGATTTCGCCTGATGGCGATTATTTCGCCCTGACTATGCCGATGGAAGATCGCA
CCGTGCTCGGTATCGTGCGACGCAAAGACAAGGCGGTCACCGCAAGAGTGACGAGTGGCGTCAACAGTGTGGTGGACGAT
TTCTGGTGGGCCGGCAACGAACGCGTGGTGATCTCGATGGCGCAACGGTTCGGTTCGCGCGATGAGCCGGCGGCGATCGG
TGAGCTGCATGCCATCGATGCCGATGGCAAGAACGGCCGTTTGCTGGCAAGCCCCTATGGCACGAATCCGGACATCAATG
GCGCGCAGCTGAAGATGGATCTGGACCCCGCCACCTACATGCTGGAGACCTTGCCGGACGATCAGCGCAACATCCTGGTA
GCGACGATTCGGTTTGGTGGCGACCCGAATGTGCGCGTCGACAAGCTGGATATCCAGACCGGCCGGCGCCGCACCGTTGC
TACCGCGCCGGTGCGGCGTGCGGACTTCGTGACCGATCGGCAAGGGCGCATTCGCTTTGCGAGCGGCGCCGATGTCACGA
ATGCGAGCAAACTGTCCTACCGCGACAACGACGACGCGCCATGGCGGTTGATCAACGATGCGGCCAGCAGCAAACATCGC
GAGTTTCCGCTCGGCTTTTCTGCCGATGGCAGCCTGGCCTACATGAGGGTGGAGCAGGACACGGGCACCGACGTATTGGC
GGCCTGGGACCCGATCACCAGTAAATCCACGCCGCTACTGCACGATGATACCGTCGATCCGTATCGCATCCTGCGCGACC
TGGATGGCATCACGCCGATCGGCGCGTCGTACATGAGCGATCGCGTGCGCAACCGCTTTTTCGACGAGAAGGCGCCGACC
GCCAAGCTGTATCGCAGCCTGGAAAAAGCCTTTGATGGCAATGCGGTCTACATCACCTCGGCCACGCGCGACCGTCGTCT
GGTGCTGGTGTATGTGTGGAGCGATCGCAACAACGGCGACTACTATCTATTTGATACGGTCAACACGCATGCCGACCGGG
TGTTCAGTCGCCGCGAATGGTTCCCGCCAGATGCGGTGCCGGCGAGCACGCAGGTCAGTTTCACGGCGCGCGATGGGCTG
GAGCTGCACGGCTATCTCACCCGCCCGCTGCATGCCGAGGCGGGCACACCGCTGCCGCTGATCGTGATGCCGTATGGCGG
TCCGTTTGGCATCTTCGATAAGTGGGAATTCGACGACGACACGCAACTGCAGGCGGTCGCAGGGTATGCGGTGCTGCGCG
TCAATTACCGTGGCTCGGCCAACTATTGGCGTTCCTTTACCGTTGCCGGCGCCAAGGAGTGGGGCGGCTGCATGCAGGAC
GACCTCACCGACGCGACGCGTTGGGCGATCGCGCAAGGCATGGCCGATGCCTCGCGCGTCTGTCTGTACGGTGCCAGTGA
CGGCGGCTATGCCGCGTTGATGGGCGTGGCCAAGGAGCCAGGCTTGTACCGCTGCGCCGCTGGTTATGTGGGCGTCTACG
ATCTGGACATGATGGCGCGCGATACCGCGCGTTATGCGCGTTGGGCCAAGAACTGGACCGGCGACTGGCTCGGCGCACGC
GACACCCTTGCGGCACGATCGCCGGTGAATCTGGCCAGCCAAATCAAGGTGCCGGTGTTTCTTGCCGCCGGCGGCAAGGA
TGAGCGCGCGCCCATCGAACACACCAAACGCATGGAGCGTGCACTCAACGCTGCTGGTGTGCCGGTGGAGTCGCTGTACT
TCCCCAACGAGGGCCACGGGTTCTGCGCCGAGCCGCATCGTCGCGCGTACTACACGCGGTTGCTGGCGTTTTTGAGCAAG
CAGTTGGGTGGCAGCACGGCGAAGTGA

Upstream 100 bases:

>100_bases
CCAATGCACGGCTTCGCACAAGCAATGGACGCAACGGCGCACCTTTGCCACCATGGCGAAATCAAGGACAGACCGTGTGG
CCGATATGTAACGTTGGACG

Downstream 100 bases:

>100_bases
GCGCGGCTGAGAACGACTGCGCCACCGCCAGGCGGGCGCGCTAGGTGCTCGGAATCGGCATGTACCACCCGTATACCCCG
GTTCCTCCGCGCTCACCTGA

Product: prolyl oligopeptidase family protein

Products: oxohex-2-enedioate [C]

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MAVGCVCALLAAMPGQAQEALDLTPYLKRDQIERIKISPDGDYFALTMPMEDRTVLGIVRRKDKAVTARVTSGVNSVVDD
FWWAGNERVVISMAQRFGSRDEPAAIGELHAIDADGKNGRLLASPYGTNPDINGAQLKMDLDPATYMLETLPDDQRNILV
ATIRFGGDPNVRVDKLDIQTGRRRTVATAPVRRADFVTDRQGRIRFASGADVTNASKLSYRDNDDAPWRLINDAASSKHR
EFPLGFSADGSLAYMRVEQDTGTDVLAAWDPITSKSTPLLHDDTVDPYRILRDLDGITPIGASYMSDRVRNRFFDEKAPT
AKLYRSLEKAFDGNAVYITSATRDRRLVLVYVWSDRNNGDYYLFDTVNTHADRVFSRREWFPPDAVPASTQVSFTARDGL
ELHGYLTRPLHAEAGTPLPLIVMPYGGPFGIFDKWEFDDDTQLQAVAGYAVLRVNYRGSANYWRSFTVAGAKEWGGCMQD
DLTDATRWAIAQGMADASRVCLYGASDGGYAALMGVAKEPGLYRCAAGYVGVYDLDMMARDTARYARWAKNWTGDWLGAR
DTLAARSPVNLASQIKVPVFLAAGGKDERAPIEHTKRMERALNAAGVPVESLYFPNEGHGFCAEPHRRAYYTRLLAFLSK
QLGGSTAK

Sequences:

>Translated_648_residues
MAVGCVCALLAAMPGQAQEALDLTPYLKRDQIERIKISPDGDYFALTMPMEDRTVLGIVRRKDKAVTARVTSGVNSVVDD
FWWAGNERVVISMAQRFGSRDEPAAIGELHAIDADGKNGRLLASPYGTNPDINGAQLKMDLDPATYMLETLPDDQRNILV
ATIRFGGDPNVRVDKLDIQTGRRRTVATAPVRRADFVTDRQGRIRFASGADVTNASKLSYRDNDDAPWRLINDAASSKHR
EFPLGFSADGSLAYMRVEQDTGTDVLAAWDPITSKSTPLLHDDTVDPYRILRDLDGITPIGASYMSDRVRNRFFDEKAPT
AKLYRSLEKAFDGNAVYITSATRDRRLVLVYVWSDRNNGDYYLFDTVNTHADRVFSRREWFPPDAVPASTQVSFTARDGL
ELHGYLTRPLHAEAGTPLPLIVMPYGGPFGIFDKWEFDDDTQLQAVAGYAVLRVNYRGSANYWRSFTVAGAKEWGGCMQD
DLTDATRWAIAQGMADASRVCLYGASDGGYAALMGVAKEPGLYRCAAGYVGVYDLDMMARDTARYARWAKNWTGDWLGAR
DTLAARSPVNLASQIKVPVFLAAGGKDERAPIEHTKRMERALNAAGVPVESLYFPNEGHGFCAEPHRRAYYTRLLAFLSK
QLGGSTAK
>Mature_647_residues
AVGCVCALLAAMPGQAQEALDLTPYLKRDQIERIKISPDGDYFALTMPMEDRTVLGIVRRKDKAVTARVTSGVNSVVDDF
WWAGNERVVISMAQRFGSRDEPAAIGELHAIDADGKNGRLLASPYGTNPDINGAQLKMDLDPATYMLETLPDDQRNILVA
TIRFGGDPNVRVDKLDIQTGRRRTVATAPVRRADFVTDRQGRIRFASGADVTNASKLSYRDNDDAPWRLINDAASSKHRE
FPLGFSADGSLAYMRVEQDTGTDVLAAWDPITSKSTPLLHDDTVDPYRILRDLDGITPIGASYMSDRVRNRFFDEKAPTA
KLYRSLEKAFDGNAVYITSATRDRRLVLVYVWSDRNNGDYYLFDTVNTHADRVFSRREWFPPDAVPASTQVSFTARDGLE
LHGYLTRPLHAEAGTPLPLIVMPYGGPFGIFDKWEFDDDTQLQAVAGYAVLRVNYRGSANYWRSFTVAGAKEWGGCMQDD
LTDATRWAIAQGMADASRVCLYGASDGGYAALMGVAKEPGLYRCAAGYVGVYDLDMMARDTARYARWAKNWTGDWLGARD
TLAARSPVNLASQIKVPVFLAAGGKDERAPIEHTKRMERALNAAGVPVESLYFPNEGHGFCAEPHRRAYYTRLLAFLSKQ
LGGSTAK

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=254, Percent_Identity=26.7716535433071, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI194394146, Length=269, Percent_Identity=27.1375464684015, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI18450280, Length=274, Percent_Identity=25.9124087591241, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI37577089, Length=274, Percent_Identity=25.9124087591241, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25144537, Length=336, Percent_Identity=27.6785714285714, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144540, Length=336, Percent_Identity=27.6785714285714, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17552908, Length=231, Percent_Identity=28.1385281385281, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25144543, Length=246, Percent_Identity=28.4552845528455, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25149159, Length=236, Percent_Identity=29.6610169491525, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550825, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45553511, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45551969, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: 3.1.1.45 [C]

Molecular weight: Translated: 71704; Mature: 71573

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGCVCALLAAMPGQAQEALDLTPYLKRDQIERIKISPDGDYFALTMPMEDRTVLGIVR
CCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEE
RKDKAVTARVTSGVNSVVDDFWWAGNERVVISMAQRFGSRDEPAAIGELHAIDADGKNGR
CCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCCEEEEECCCCCCCE
LLASPYGTNPDINGAQLKMDLDPATYMLETLPDDQRNILVATIRFGGDPNVRVDKLDIQT
EEECCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCC
GRRRTVATAPVRRADFVTDRQGRIRFASGADVTNASKLSYRDNDDAPWRLINDAASSKHR
CCCEEEEECCCCHHHCEECCCCCEEEECCCCCCCCCEEECCCCCCCCEEEECHHHCCCCC
EFPLGFSADGSLAYMRVEQDTGTDVLAAWDPITSKSTPLLHDDTVDPYRILRDLDGITPI
CCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHCCCCCC
GASYMSDRVRNRFFDEKAPTAKLYRSLEKAFDGNAVYITSATRDRRLVLVYVWSDRNNGD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCC
YYLFDTVNTHADRVFSRREWFPPDAVPASTQVSFTARDGLELHGYLTRPLHAEAGTPLPL
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCEECCCCCCCEE
IVMPYGGPFGIFDKWEFDDDTQLQAVAGYAVLRVNYRGSANYWRSFTVAGAKEWGGCMQD
EEEECCCCCCCCCCCCCCCCCCCEEEECEEEEEEEECCCCCCCEEEEECCCHHHCCCHHH
DLTDATRWAIAQGMADASRVCLYGASDGGYAALMGVAKEPGLYRCAAGYVGVYDLDMMAR
HHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCEEEEHHHHHH
DTARYARWAKNWTGDWLGARDTLAARSPVNLASQIKVPVFLAAGGKDERAPIEHTKRMER
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCHHHHHHHHH
ALNAAGVPVESLYFPNEGHGFCAEPHRRAYYTRLLAFLSKQLGGSTAK
HHHHCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AVGCVCALLAAMPGQAQEALDLTPYLKRDQIERIKISPDGDYFALTMPMEDRTVLGIVR
CHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEE
RKDKAVTARVTSGVNSVVDDFWWAGNERVVISMAQRFGSRDEPAAIGELHAIDADGKNGR
CCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCCEEEEECCCCCCCE
LLASPYGTNPDINGAQLKMDLDPATYMLETLPDDQRNILVATIRFGGDPNVRVDKLDIQT
EEECCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCC
GRRRTVATAPVRRADFVTDRQGRIRFASGADVTNASKLSYRDNDDAPWRLINDAASSKHR
CCCEEEEECCCCHHHCEECCCCCEEEECCCCCCCCCEEECCCCCCCCEEEECHHHCCCCC
EFPLGFSADGSLAYMRVEQDTGTDVLAAWDPITSKSTPLLHDDTVDPYRILRDLDGITPI
CCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHCCCCCC
GASYMSDRVRNRFFDEKAPTAKLYRSLEKAFDGNAVYITSATRDRRLVLVYVWSDRNNGD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCC
YYLFDTVNTHADRVFSRREWFPPDAVPASTQVSFTARDGLELHGYLTRPLHAEAGTPLPL
EEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCEECCCCCCCEE
IVMPYGGPFGIFDKWEFDDDTQLQAVAGYAVLRVNYRGSANYWRSFTVAGAKEWGGCMQD
EEEECCCCCCCCCCCCCCCCCCCEEEECEEEEEEEECCCCCCCEEEEECCCHHHCCCHHH
DLTDATRWAIAQGMADASRVCLYGASDGGYAALMGVAKEPGLYRCAAGYVGVYDLDMMAR
HHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCEEEEHHHHHH
DTARYARWAKNWTGDWLGARDTLAARSPVNLASQIKVPVFLAAGGKDERAPIEHTKRMER
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCHHHHHHHHH
ALNAAGVPVESLYFPNEGHGFCAEPHRRAYYTRLLAFLSKQLGGSTAK
HHHHCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-carboxymethylenebut-2-en-4-olide; H2O [C]

Specific reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]