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The map label for this gene is emrK [H]

Identifier: 84625412

GI number: 84625412

Start: 4246686

End: 4247762

Strand: Reverse

Name: emrK [H]

Synonym: XOO_3755

Alternate gene names: 84625412

Gene position: 4247762-4246686 (Counterclockwise)

Preceding gene: 84625413

Following gene: 84625411

Centisome position: 85.98

GC content: 66.57

Gene sequence:

>1077_bases
ATGAATACACCAGCGGATTCTTCACCGCCTGCCTGCCGGCAACGTCGTCGGCGTAGCCGCATTGCTGGCGTCATCGGCTT
TGGCGGGCTTGCGCTGATCGGCGTGGCGCTGGTGCTCTATGCATGGCGACTGCCGCCGTTCGTCAGTGCGATCGAACGTA
CCGAAAATGCGCTGGTGCTCGGCCAGATCACGGTGATTGCGCCGCAGGTCAGCGGCTATGTGACCCAAGTCCCCGTGCAG
GATTTTGCGCACGTGAAACGCGGCCAGTTGCTGGCCAAAATCGACGACCGCATCTACGCCCAGCAGCTCGAACAGGCCAA
TGCGCAGATGCAAACCGCGCAAGCCAATCTCGCCAACTGGGAGCAGCAACGGCACAGCGCCGAGGCGACGATTGCCGAGC
AGCGCGCAGCACTGAGCAGCAACCAGGCGCAACGCGACCGCACCCGTTCGGCCTATGCCCGCACGCAGCAGCTGGCCAGC
CAGCAACTGGTGTCCGAGCAGGACCGCGACACTGCATTTGCCGCACGCGCGCAGGCCGATGCCGGCGTGGTGCAGGCACG
CGCCGCGGTACAGGCCGCCGAAGAAAACGCACGCGGCGTTACCGTCAACCGCGCCGCGTTGGAGGCGGCTGTCGCCAACG
CGCAAGCCGCCGTGCGACTGGCGCAGATCAACCTGGACAACACGCGCATCCTGGCCCCGCGCGATGGTCAGCTGGGCGTG
CGCCAGGGCGCCTATGTCACCAACGGCACGCAGCTGATGTCGCTGGTGCCGGACACGCTGTGGATCGTGGCCAATTTCAA
GGAAACCCAGATGGCGAAGATCCGCATCGGCCAGCGTGCCAGCTTCACCGTGGATGCGCTGGACAACGCTCGCCTGCACG
GCCGCGTGCAGGACATTTCGCCGGCGGCCGGCTCGGAGTTCAGCGTGCTGCCGGCCGATAACGCCGCCGGTAACTTCGTC
AAGATTGCCCAGCGCATTCCGCTGCGCATCAGCGTCGACCCCGACCAGCCGCTGGCCCCGCGGCTGCGGCCAGGCATGTC
GGTGGTGGCCGTCGATACCGCCAGCCCAGTCGACTGA

Upstream 100 bases:

>100_bases
TCGCCATCGCGACCGGCGTATGGATCCTGTCCGTGCTGGTGTGGCGCCGCTATCTGCGCCCACCGGTCTCGCCCTCTCCT
CCTGTTCCCAGTGTGCGCCC

Downstream 100 bases:

>100_bases
GCACAACCGACACAACCAATACCGACGCGTAGGCGGGCAGTGTCGGCGCGAACGCTGCAGCTGGCATTGCCTAGTGTCGC
GTTCCGCATGTAACTTTTCT

Product: multidrug resistance efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNTPADSSPPACRQRRRRSRIAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENALVLGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLAKIDDRIYAQQLEQANAQMQTAQANLANWEQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVVQARAAVQAAEENARGVTVNRAALEAAVANAQAAVRLAQINLDNTRILAPRDGQLGV
RQGAYVTNGTQLMSLVPDTLWIVANFKETQMAKIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNAAGNFV
KIAQRIPLRISVDPDQPLAPRLRPGMSVVAVDTASPVD

Sequences:

>Translated_358_residues
MNTPADSSPPACRQRRRRSRIAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENALVLGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLAKIDDRIYAQQLEQANAQMQTAQANLANWEQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVVQARAAVQAAEENARGVTVNRAALEAAVANAQAAVRLAQINLDNTRILAPRDGQLGV
RQGAYVTNGTQLMSLVPDTLWIVANFKETQMAKIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNAAGNFV
KIAQRIPLRISVDPDQPLAPRLRPGMSVVAVDTASPVD
>Mature_358_residues
MNTPADSSPPACRQRRRRSRIAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENALVLGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLAKIDDRIYAQQLEQANAQMQTAQANLANWEQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVVQARAAVQAAEENARGVTVNRAALEAAVANAQAAVRLAQINLDNTRILAPRDGQLGV
RQGAYVTNGTQLMSLVPDTLWIVANFKETQMAKIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNAAGNFV
KIAQRIPLRISVDPDQPLAPRLRPGMSVVAVDTASPVD

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=349, Percent_Identity=33.2378223495702, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789041, Length=334, Percent_Identity=33.5329341317365, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1790519, Length=335, Percent_Identity=28.0597014925373, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081951, Length=318, Percent_Identity=27.0440251572327, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789637, Length=330, Percent_Identity=26.0606060606061, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081796, Length=307, Percent_Identity=27.3615635179153, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790024, Length=284, Percent_Identity=27.112676056338, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38546; Mature: 38546

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPADSSPPACRQRRRRSRIAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENALVL
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLAKIDDRIYAQQLEQANAQMQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLASQQLVSEQDRDTAFAARAQAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
AGVVQARAAVQAAEENARGVTVNRAALEAAVANAQAAVRLAQINLDNTRILAPRDGQLGV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCEEECCCCCCCCC
RQGAYVTNGTQLMSLVPDTLWIVANFKETQMAKIRIGQRASFTVDALDNARLHGRVQDIS
CCCCEEECCHHHHHHCCCEEEEEECCCHHHEEEEEECCCCCEEEECCCCCHHCCEEECCC
PAAGSEFSVLPADNAAGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVAVDTASPVD
CCCCCCEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MNTPADSSPPACRQRRRRSRIAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENALVL
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLAKIDDRIYAQQLEQANAQMQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLASQQLVSEQDRDTAFAARAQAD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
AGVVQARAAVQAAEENARGVTVNRAALEAAVANAQAAVRLAQINLDNTRILAPRDGQLGV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCEEECCCCCCCCC
RQGAYVTNGTQLMSLVPDTLWIVANFKETQMAKIRIGQRASFTVDALDNARLHGRVQDIS
CCCCEEECCHHHHHHCCCEEEEEECCCHHHEEEEEECCCCCEEEECCCCCHHCCEEECCC
PAAGSEFSVLPADNAAGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVAVDTASPVD
CCCCCCEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]