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The map label for this gene is dacC [H]

Identifier: 84625391

GI number: 84625391

Start: 4220937

End: 4222142

Strand: Reverse

Name: dacC [H]

Synonym: XOO_3734

Alternate gene names: 84625391

Gene position: 4222142-4220937 (Counterclockwise)

Preceding gene: 84625392

Following gene: 84625390

Centisome position: 85.46

GC content: 64.43

Gene sequence:

>1206_bases
ATGAAATTCCGCTTCGCCGCCGCTGCCGTGGCCACGTTCGCCTTCGGCCTGGTCTGCGCCCAGACACCTGCGCCGCAGCC
GATTCCCGCCGTGGCTGCCGCCCCGGCCGCCTTGCCGGTACCACCGGCACCCGCACCGGCCGTGTCCAAGTCCTGGATCC
TGATGGACTACGCCACCGGGCAGGTGCTGGCTGGTGAGAACATCCACCAGCAGCTGGCCCCGGCCAGCATCACCAAGGTG
ATGACGTCCTACGTGGTCGCTGCCGAAATCAAGAACGGCAAGGTCAAGCGCGACGACCAGGTCATGATGAGCGAGCGCGC
CTGGCGCGAGGGCGGTGCGGGCACCGACGGCAGCTACAGCGGCTTCCCGGTCAACCAGACGGCGCGTCTGGAAGACATGG
AAAAAGGCATGGCGATCCAGTCCGGCAACGATGCCGCCATCGCACTGGCCGAGCATGTGGCCGGTAGCGAAGAAGCCTTC
GCCTCGCTGATGAACACCTACGCCGCCAAGATCGGCATGAAGGATTCGTACTTCGTCAACGCGCACGGCTTGAGCGCCGA
AGGGCACCACTCCAGCGCTTACGATCTGGCCATGCTGGGCCGCGCGATGGTGCGCGATTACCCGGACACCTACGCCTATA
ACAAGATCAAGGAATTCCAGGTCGGCAGCATCAAGCAGAGCAACCGTAACCGGCTGCTGTGGCGCGACCCGGCAGTGGAC
GGCATCAAGACCGGCCACACCTCCGAGGCCGGCTACTGCCTGCTGAGCTCGGCCAAGCGTGACGACCAGCGCCTGATCGC
CGTAGTCATGGGCGACAGTTCCGAAGAACAGCGCGCCACCGATAGCCTGGCTCTGCTCAACTGGGGCTTCCGCTTCTTCG
AAACCCACAGCTTGTACGCGCCCGGTAAGGTCGTGACCAAGCAGAAGGTCTGGAAGGGCCAGCAGGACGAAGTGCAACTC
GGCGTCGCACAGCCGCTGCTGGTCAGCCTGCAGCGCGGCCGTTACAACGACCTCAAGCCCAGCATGGAAGTGCCCAAGAA
CCTGCAGGCACCGATCAAGCAGGGCCAGCAAGTCGGCACCGTGAAGGTCAGCCTGGACGGCAAGGTCATCGCCCAGGCCC
CGCTGGTCGCCATCAACGCGGTCGAAGAGGGCGGATTCTTCAAGCGCCTCTGGGATGCGTTCTGGATGTGGTGGAAGTCG
GAGTAA

Upstream 100 bases:

>100_bases
TGCGCAAGCGCGTGCAACCTGCGACGCGTCGCCCTGATCGCCATAGCGCCTTACAATTTCGCATTGCCCGGCTTTCGGGC
CCGTCAGGAGTCGTTCTTCA

Downstream 100 bases:

>100_bases
TTCAAACAAAAAAGCCGGCTTTCGTCGGCTTTTTTGTTTGCGGGATTGGGGATTGGGCATTTGGGATTCGCAAAAGCGAG
GGCAGCGGCGAAGCCCCGCG

Product: penicillin-binding protein 6

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKFRFAAAAVATFAFGLVCAQTPAPQPIPAVAAAPAALPVPPAPAPAVSKSWILMDYATGQVLAGENIHQQLAPASITKV
MTSYVVAAEIKNGKVKRDDQVMMSERAWREGGAGTDGSYSGFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAF
ASLMNTYAAKIGMKDSYFVNAHGLSAEGHHSSAYDLAMLGRAMVRDYPDTYAYNKIKEFQVGSIKQSNRNRLLWRDPAVD
GIKTGHTSEAGYCLLSSAKRDDQRLIAVVMGDSSEEQRATDSLALLNWGFRFFETHSLYAPGKVVTKQKVWKGQQDEVQL
GVAQPLLVSLQRGRYNDLKPSMEVPKNLQAPIKQGQQVGTVKVSLDGKVIAQAPLVAINAVEEGGFFKRLWDAFWMWWKS
E

Sequences:

>Translated_401_residues
MKFRFAAAAVATFAFGLVCAQTPAPQPIPAVAAAPAALPVPPAPAPAVSKSWILMDYATGQVLAGENIHQQLAPASITKV
MTSYVVAAEIKNGKVKRDDQVMMSERAWREGGAGTDGSYSGFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAF
ASLMNTYAAKIGMKDSYFVNAHGLSAEGHHSSAYDLAMLGRAMVRDYPDTYAYNKIKEFQVGSIKQSNRNRLLWRDPAVD
GIKTGHTSEAGYCLLSSAKRDDQRLIAVVMGDSSEEQRATDSLALLNWGFRFFETHSLYAPGKVVTKQKVWKGQQDEVQL
GVAQPLLVSLQRGRYNDLKPSMEVPKNLQAPIKQGQQVGTVKVSLDGKVIAQAPLVAINAVEEGGFFKRLWDAFWMWWKS
E
>Mature_401_residues
MKFRFAAAAVATFAFGLVCAQTPAPQPIPAVAAAPAALPVPPAPAPAVSKSWILMDYATGQVLAGENIHQQLAPASITKV
MTSYVVAAEIKNGKVKRDDQVMMSERAWREGGAGTDGSYSGFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAF
ASLMNTYAAKIGMKDSYFVNAHGLSAEGHHSSAYDLAMLGRAMVRDYPDTYAYNKIKEFQVGSIKQSNRNRLLWRDPAVD
GIKTGHTSEAGYCLLSSAKRDDQRLIAVVMGDSSEEQRATDSLALLNWGFRFFETHSLYAPGKVVTKQKVWKGQQDEVQL
GVAQPLLVSLQRGRYNDLKPSMEVPKNLQAPIKQGQQVGTVKVSLDGKVIAQAPLVAINAVEEGGFFKRLWDAFWMWWKS
E

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=365, Percent_Identity=47.3972602739726, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1786851, Length=363, Percent_Identity=43.2506887052342, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI87082022, Length=397, Percent_Identity=38.7909319899244, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI87082054, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43600; Mature: 43600

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFAAAAVATFAFGLVCAQTPAPQPIPAVAAAPAALPVPPAPAPAVSKSWILMDYATG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
QVLAGENIHQQLAPASITKVMTSYVVAAEIKNGKVKRDDQVMMSERAWREGGAGTDGSYS
CEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAFASLMNTYAAKIGMKDSYFVN
CCCCCCCHHHHHHHCCCEEECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
AHGLSAEGHHSSAYDLAMLGRAMVRDYPDTYAYNKIKEFQVGSIKQSNRNRLLWRDPAVD
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
GIKTGHTSEAGYCLLSSAKRDDQRLIAVVMGDSSEEQRATDSLALLNWGFRFFETHSLYA
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHEEECCCCCC
PGKVVTKQKVWKGQQDEVQLGVAQPLLVSLQRGRYNDLKPSMEVPKNLQAPIKQGQQVGT
CCCHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEE
VKVSLDGKVIAQAPLVAINAVEEGGFFKRLWDAFWMWWKSE
EEEEECCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFRFAAAAVATFAFGLVCAQTPAPQPIPAVAAAPAALPVPPAPAPAVSKSWILMDYATG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
QVLAGENIHQQLAPASITKVMTSYVVAAEIKNGKVKRDDQVMMSERAWREGGAGTDGSYS
CEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GFPVNQTARLEDMEKGMAIQSGNDAAIALAEHVAGSEEAFASLMNTYAAKIGMKDSYFVN
CCCCCCCHHHHHHHCCCEEECCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
AHGLSAEGHHSSAYDLAMLGRAMVRDYPDTYAYNKIKEFQVGSIKQSNRNRLLWRDPAVD
ECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
GIKTGHTSEAGYCLLSSAKRDDQRLIAVVMGDSSEEQRATDSLALLNWGFRFFETHSLYA
CCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHEEECCCCCC
PGKVVTKQKVWKGQQDEVQLGVAQPLLVSLQRGRYNDLKPSMEVPKNLQAPIKQGQQVGT
CCCHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEE
VKVSLDGKVIAQAPLVAINAVEEGGFFKRLWDAFWMWWKSE
EEEEECCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]