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The map label for this gene is nrdR [H]

Identifier: 84625294

GI number: 84625294

Start: 4113230

End: 4113754

Strand: Reverse

Name: nrdR [H]

Synonym: XOO_3637

Alternate gene names: 84625294

Gene position: 4113754-4113230 (Counterclockwise)

Preceding gene: 84625295

Following gene: 84625293

Centisome position: 83.27

GC content: 61.71

Gene sequence:

>525_bases
ATGCATTGCCCCTTCTGCCAGCACAGCGACACCCGCGTGATCGATTCGCGGGTGTCCGAAGACGGCACGACGATTCGTCG
GCGCCGTGAGTGCGAGGCATGCGGTGAGCGTTTCAGCACGTTGGAAACGATCGAACTGAAGTTGCCCACCGTGGTCAAGA
GCGATGGTGGGCGCGAAGCGTTCGATGCACGCAAGCTGCGCACCAGTTTCGACCGCGCGCTGCAGAAGCGGCCGGTGGCC
GAGGAACAAATCGAAGCAGCGGTACGCTCAGTCGTGCATCAGCTGCGGATGTCGGGCGAGCGCGAAGTGGGCTCGCTGCG
CGTAGGCGAATACGTGATGGTGGAGCTGCGCAAGCTCGATCATGTCGGCTATGTGCGCTTTGCTTCGGTGTATCGCAGTT
TCCAGGACGTGGCCGATTTTCGTGAGGAAATCGAGAAGCTCGAACGCGAACTGCCGGTCGGCAGCGAACAACTGCCATTG
CTGGAAGTGGCACTGGAACGCGCCGGCAAGCCCGGCAAGCGATGA

Upstream 100 bases:

>100_bases
CGCTCACGCGGTCGGGTGCTGCCTGGAACGCGATGGCAGCCGGGATGGAATGGCGGCTCGCGTTTGCCCGGCAGCCCGGA
ATGTTGGAAGAACACCGCTA

Downstream 100 bases:

>100_bases
GCGCGATGCGCATCGCCTGCGTTGCGGAAACGCCAGCGTATCTGCCTGAGATTGCGCAAGCGCATCTGCAGGCCTTCGGC
ACGTTGCTGCCGGAATGGAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEVALERAGKPGKR

Sequences:

>Translated_174_residues
MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEVALERAGKPGKR
>Mature_174_residues
MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEVALERAGKPGKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=54.7297297297297, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 19948; Mature: 19948

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEECCCCCHH
FDARKLRTSFDRALQKRPVAEEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEVALERAGKPGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHCPFCQHSDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEECCCCCHH
FDARKLRTSFDRALQKRPVAEEQIEAAVRSVVHQLRMSGEREVGSLRVGEYVMVELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEVALERAGKPGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]