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The map label for this gene is ribD [H]

Identifier: 84625292

GI number: 84625292

Start: 4111642

End: 4112751

Strand: Reverse

Name: ribD [H]

Synonym: XOO_3635

Alternate gene names: 84625292

Gene position: 4112751-4111642 (Counterclockwise)

Preceding gene: 84625293

Following gene: 84625290

Centisome position: 83.25

GC content: 66.04

Gene sequence:

>1110_bases
ATGAGTGAGACCGCGGCGATCGCGAGTGCCGATGACCACCGCTGGATGGCGCAGGCGTTGCGCTTGGCCGAGCGCGGCGC
CTACACCACCCGCCCCAATCCGATGGTGGGCTGCGTGATTGTGCGCGATGGCGTGTGCGTGGGCGAAGGCTTTCATCAAC
GTGCGGGTGGCCCGCATGCCGAAGTCTTCGCGTTGCGTGCGGCCGGTGAGTTGGCGCGCGGTGCCACTGCGTATGTGACC
CTGGAGCCATGCGCGCATTACGGGCGCACGCCGCCGTGTGCGTTGGCGTTGATCGAGGCAGGCGTAACGCGTGTGGTCGC
GGCGATGGCCGATCCGTTTCCGCAGGTCAATGGCGGTGGTTTTGCGTTGCTGCGCGACGCTGGAATCGAGGTGCTCAGCG
GGGTGATGCACGCGCAGGCGCGCACGCTCAATCAGGGCTTTCTGTCGCGGGTGGAGCGTGGCCGGCCGTGGCTGCGGGTC
AAACTGGGCGCCAGCCTTGACGGGCGGACCGCGTTGGCCAGCGGCCAATCCAAATGGATCACCGGAGCCGACGCGCGTGC
GGACGTGCAGCGTTGGCGTGCGCGTGCCGGCGCAATCCTCACTGGTGCTGGCACGGTGTTGGCCGATGATCCGTCGATGA
CGGTGCGGCTGGGCGATGACATCGCGTGCGTGCCACCGCTGCGTGTGGTGCTGGATGCCGGCTTACGCACGTTGGCGTGC
AAGAACATCCGCAATGGCGATGCGCCGACGCTGTATCTGCATGGCGATGCTGTCGCTGCAACCGCGCTGGATGGTGCGGA
ATGTGCGGCACTGCCATTGCACGTGGGCCGTTTCGATCTGTCCGCAGTGCTGGCGTTGCTGGCCGAGCGCGGCATCAATG
AAGTGCATGTTGAAGCCGGCGCCACGCTGAGTGGTGCGCTGTTGCAGGCCGGGCTGGTGGACGAACTGCTGGTCTACATG
GCGCCGGTGTTGCTGGGCGACACCGCAAGGCCCTTGCTCGCTGGCCTTGGCATCGAAACGATGGCTCAGCGCTACGAATT
GCAACTACGCGATGTACGTCAGCTCGGGCAGGATCTGCGTTTGCGTTACGCGCCATCAGCGGTGGTATGA

Upstream 100 bases:

>100_bases
TGCCGTTTTATCAGCGGCTGGGATGGCAGACGCATGCCGAATTCTTACTAGGCCCAATGCACATCGTGGTGATGCGCAGC
GCGCCGGGAGCAGTGACGCG

Downstream 100 bases:

>100_bases
GTGCAAAAAAAGGCCCCGCATGCGGGGCTTTTTCTTATTTCATGCACGAAGCCGGTCAGAAGCTCGCGCGCACGCCGATG
CGGTACTGATTTGCGTTGTC

Product: riboflavin-specific deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSETAAIASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVT
LEPCAHYGRTPPCALALIEAGVTRVVAAMADPFPQVNGGGFALLRDAGIEVLSGVMHAQARTLNQGFLSRVERGRPWLRV
KLGASLDGRTALASGQSKWITGADARADVQRWRARAGAILTGAGTVLADDPSMTVRLGDDIACVPPLRVVLDAGLRTLAC
KNIRNGDAPTLYLHGDAVAATALDGAECAALPLHVGRFDLSAVLALLAERGINEVHVEAGATLSGALLQAGLVDELLVYM
APVLLGDTARPLLAGLGIETMAQRYELQLRDVRQLGQDLRLRYAPSAVV

Sequences:

>Translated_369_residues
MSETAAIASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVT
LEPCAHYGRTPPCALALIEAGVTRVVAAMADPFPQVNGGGFALLRDAGIEVLSGVMHAQARTLNQGFLSRVERGRPWLRV
KLGASLDGRTALASGQSKWITGADARADVQRWRARAGAILTGAGTVLADDPSMTVRLGDDIACVPPLRVVLDAGLRTLAC
KNIRNGDAPTLYLHGDAVAATALDGAECAALPLHVGRFDLSAVLALLAERGINEVHVEAGATLSGALLQAGLVDELLVYM
APVLLGDTARPLLAGLGIETMAQRYELQLRDVRQLGQDLRLRYAPSAVV
>Mature_368_residues
SETAAIASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHAEVFALRAAGELARGATAYVTL
EPCAHYGRTPPCALALIEAGVTRVVAAMADPFPQVNGGGFALLRDAGIEVLSGVMHAQARTLNQGFLSRVERGRPWLRVK
LGASLDGRTALASGQSKWITGADARADVQRWRARAGAILTGAGTVLADDPSMTVRLGDDIACVPPLRVVLDAGLRTLACK
NIRNGDAPTLYLHGDAVAATALDGAECAALPLHVGRFDLSAVLALLAERGINEVHVEAGATLSGALLQAGLVDELLVYMA
PVLLGDTARPLLAGLGIETMAQRYELQLRDVRQLGQDLRLRYAPSAVV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=362, Percent_Identity=51.3812154696133, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38798; Mature: 38667

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETAAIASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHA
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCHHHHCCCCCH
EVFALRAAGELARGATAYVTLEPCAHYGRTPPCALALIEAGVTRVVAAMADPFPQVNGGG
HEEEEHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FALLRDAGIEVLSGVMHAQARTLNQGFLSRVERGRPWLRVKLGASLDGRTALASGQSKWI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCEE
TGADARADVQRWRARAGAILTGAGTVLADDPSMTVRLGDDIACVPPLRVVLDAGLRTLAC
ECCCCHHHHHHHHHHCCEEEECCCEEEECCCCEEEEECCCEECCCHHHHHHHCCHHHHHH
KNIRNGDAPTLYLHGDAVAATALDGAECAALPLHVGRFDLSAVLALLAERGINEVHVEAG
HCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECC
ATLSGALLQAGLVDELLVYMAPVLLGDTARPLLAGLGIETMAQRYELQLRDVRQLGQDLR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCE
LRYAPSAVV
EEECCCCCC
>Mature Secondary Structure 
SETAAIASADDHRWMAQALRLAERGAYTTRPNPMVGCVIVRDGVCVGEGFHQRAGGPHA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCHHHHCCCCCH
EVFALRAAGELARGATAYVTLEPCAHYGRTPPCALALIEAGVTRVVAAMADPFPQVNGGG
HEEEEHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FALLRDAGIEVLSGVMHAQARTLNQGFLSRVERGRPWLRVKLGASLDGRTALASGQSKWI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCEE
TGADARADVQRWRARAGAILTGAGTVLADDPSMTVRLGDDIACVPPLRVVLDAGLRTLAC
ECCCCHHHHHHHHHHCCEEEECCCEEEECCCCEEEEECCCEECCCHHHHHHHCCHHHHHH
KNIRNGDAPTLYLHGDAVAATALDGAECAALPLHVGRFDLSAVLALLAERGINEVHVEAG
HCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECC
ATLSGALLQAGLVDELLVYMAPVLLGDTARPLLAGLGIETMAQRYELQLRDVRQLGQDLR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCE
LRYAPSAVV
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]