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The map label for this gene is ppiD [H]

Identifier: 84622593

GI number: 84622593

Start: 1022747

End: 1024717

Strand: Direct

Name: ppiD [H]

Synonym: XOO_0936

Alternate gene names: 84622593

Gene position: 1022747-1024717 (Clockwise)

Preceding gene: 84622592

Following gene: 84622596

Centisome position: 20.7

GC content: 62.86

Gene sequence:

>1971_bases
ATGCTGCAGAAACTTCGCGACAAGACGTCAGGCTGGATCGCTACCGCCATCCTGGGGTTGCTGATGATTCCGTTCCTGTT
CGTCATCGATAACAGCTACCTCGGCGGCATTGGTGCCAATAACGTGGCCAAGGTGCAGGCGCCGCCGAATTGGTGGAAGT
CGGCACCATCGTGGTGGCCGGTGTCTTTGCTGTGGCAGCACCACGAAATCAGCACGCAGGATTTCCGCGCGCGTTTCGAA
CAGGCGCGCATGCAGGAGCGTCAGCGTCAGGGCGAGAACTTCGATCCGCGCACTTTCGAATCCCGCGAAAACAAGCTGCA
GGTACTCGATCAACTGGTCGACGAACAGGTGGTGCGACTGGGCGCGGAAGATGCCGGAATCGTCATCGGCGATGCGAGCG
TGCGCGATTACATCGCCAACATTCAGGCGTTCCAGGTCGATGGCAAGTTCAGTCCTGACAAGTACCGTGCTGCGCTCGCG
CAAGGCACGCCGCCGCGCACGCCTGCACAGTTCGACGCCCTGGTGCGCGATAGTCTGCAGCAGTCGGTCATCCCACAGGC
TATTGCCGACTCGGGCTTTGCCACCAAGTCCGAGTTCGAGCGTCTGCTCAAGCTGATGGGTGAAACGCGCGACGTGGAGT
TGGCGATGCTGCCGCCGCCGGCCATGGATACCGCGCCGGTGAGCGATGCGCAGATCAAGCAGTGGTATGACGGACACACG
CAGGACTTCCGTCAGCCGGAAACCGTCACCATCGAATACGTGGAGCTCAACGCCGCGACGATGCGGCCAGCGACTGCCGC
CGACGAGGCAACGCTGCGCAAGCGCTATGAAGAAGAAAAGGCACGCTTTGTCGAGCCGGACCAGCGCCTTGCATCGCACA
TCCTGATCAGTGCCGGCAGCGATGCGGCAGCGCAGAAGGCTGCCGAAGCGAAGGCAGCCAAGCTCGCCGCTGAGGCCAAG
GCGCCGGGCGCCGATTTCGCTGCACTTGCGAAAGCCAATTCGCAGGATCCCGGCTCCAAGGATGCCGGTGGCGACCTGGG
CTGGGTCGAGAAGGGCACCATGGTCAAGCCGTTCGAGGATGCACTGTTCTCGATGAAGGCTGGCGACGTGGTGGGCCCGA
TCAAGAGCGAATTCGGCTACCACGTGATCCAGCTGCGTGAGGTCAAGGGTGGCCAGGGCAAGTCCTTCGAGCAGGTGCGT
GACAAGCTGGCTGCCGAGCAGCTGAAGGCCGATGCGGACAAGGCATTTGCCGATGTCAGTGGCAAGTTGGTGGACCAGCT
CTACAAGAATCCCACTGCACTGGAGCCGGCGGCCAAGCAGGTCGGCCTGCCGGTGCAGACCTTGGGGCCGTTCTCGCGTA
GTGATGCCAGCGGTGTTGCGGCCAATCCTGCTGTGCTGCGTGCAGCGTTCTCTGAAACGCTGGTTCAGGACGGCACGGTG
AGCGACCCAATCAACATCGCGCCGAACCATAGCGTGGTGTTGCGTGTGACCAATCACACCGCCGAGCAGGCGTTGCTTTT
GGACAAGGTGCGCGACAAGGTGACGGCGGCGATCCGTGCGGACCGTGCCGAGAAGGCCGCCGCGGCTGCTGCCGATGCCT
TGCTGGCACGCGTGCAGAGGGGGGAGACGCTGCAAGCGTTGGCCGCCAGCGAGAAGCTGCAGGTGCAGCCGATCCCAGGG
CTGCCGCGGACGGCGCCGATCCCGACCCCGGCCGCGAACCGCGCAATTTTCAGCGCGCCGCGACCGACCGAAGGTAAGCC
CTCGTTTGGCAAGGTGGAATTGGATGGCGGGCGCTTTGCCGTCTTTGCCATCAGCAAGGCCACCCCGGGCAATCTGAAAC
AGATGCCGGCCGAGCAGCAGACCATGCTGCGCGAGCAGCTGAGCCAGATCGACGGCAACAACGCTGCGCAGACTTACGTC
AAGCAAATGCGCAAGCGCTACAAGATCCAGATCGAAGAAGCGCAGCTGTAA

Upstream 100 bases:

>100_bases
CGATTGATGGGCCGCGACACCGTGCTAACGGGCATCGGGCTGGGTGCTTGGCGTCAAGCGCGTTACACTGCGCGGCTCGC
CCACAGGCCGTGATTTGCCA

Downstream 100 bases:

>100_bases
GGCCGAATGATCGATTGGTGAAACAAAAAGCCCGGGTAACCGGGCTTTTTGTTTGGGTTTCTGGTGGAAAAAGACAGGTC
GGCGGATGTGCAAGGGATCG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MLQKLRDKTSGWIATAILGLLMIPFLFVIDNSYLGGIGANNVAKVQAPPNWWKSAPSWWPVSLLWQHHEISTQDFRARFE
QARMQERQRQGENFDPRTFESRENKLQVLDQLVDEQVVRLGAEDAGIVIGDASVRDYIANIQAFQVDGKFSPDKYRAALA
QGTPPRTPAQFDALVRDSLQQSVIPQAIADSGFATKSEFERLLKLMGETRDVELAMLPPPAMDTAPVSDAQIKQWYDGHT
QDFRQPETVTIEYVELNAATMRPATAADEATLRKRYEEEKARFVEPDQRLASHILISAGSDAAAQKAAEAKAAKLAAEAK
APGADFAALAKANSQDPGSKDAGGDLGWVEKGTMVKPFEDALFSMKAGDVVGPIKSEFGYHVIQLREVKGGQGKSFEQVR
DKLAAEQLKADADKAFADVSGKLVDQLYKNPTALEPAAKQVGLPVQTLGPFSRSDASGVAANPAVLRAAFSETLVQDGTV
SDPINIAPNHSVVLRVTNHTAEQALLLDKVRDKVTAAIRADRAEKAAAAAADALLARVQRGETLQALAASEKLQVQPIPG
LPRTAPIPTPAANRAIFSAPRPTEGKPSFGKVELDGGRFAVFAISKATPGNLKQMPAEQQTMLREQLSQIDGNNAAQTYV
KQMRKRYKIQIEEAQL

Sequences:

>Translated_656_residues
MLQKLRDKTSGWIATAILGLLMIPFLFVIDNSYLGGIGANNVAKVQAPPNWWKSAPSWWPVSLLWQHHEISTQDFRARFE
QARMQERQRQGENFDPRTFESRENKLQVLDQLVDEQVVRLGAEDAGIVIGDASVRDYIANIQAFQVDGKFSPDKYRAALA
QGTPPRTPAQFDALVRDSLQQSVIPQAIADSGFATKSEFERLLKLMGETRDVELAMLPPPAMDTAPVSDAQIKQWYDGHT
QDFRQPETVTIEYVELNAATMRPATAADEATLRKRYEEEKARFVEPDQRLASHILISAGSDAAAQKAAEAKAAKLAAEAK
APGADFAALAKANSQDPGSKDAGGDLGWVEKGTMVKPFEDALFSMKAGDVVGPIKSEFGYHVIQLREVKGGQGKSFEQVR
DKLAAEQLKADADKAFADVSGKLVDQLYKNPTALEPAAKQVGLPVQTLGPFSRSDASGVAANPAVLRAAFSETLVQDGTV
SDPINIAPNHSVVLRVTNHTAEQALLLDKVRDKVTAAIRADRAEKAAAAAADALLARVQRGETLQALAASEKLQVQPIPG
LPRTAPIPTPAANRAIFSAPRPTEGKPSFGKVELDGGRFAVFAISKATPGNLKQMPAEQQTMLREQLSQIDGNNAAQTYV
KQMRKRYKIQIEEAQL
>Mature_656_residues
MLQKLRDKTSGWIATAILGLLMIPFLFVIDNSYLGGIGANNVAKVQAPPNWWKSAPSWWPVSLLWQHHEISTQDFRARFE
QARMQERQRQGENFDPRTFESRENKLQVLDQLVDEQVVRLGAEDAGIVIGDASVRDYIANIQAFQVDGKFSPDKYRAALA
QGTPPRTPAQFDALVRDSLQQSVIPQAIADSGFATKSEFERLLKLMGETRDVELAMLPPPAMDTAPVSDAQIKQWYDGHT
QDFRQPETVTIEYVELNAATMRPATAADEATLRKRYEEEKARFVEPDQRLASHILISAGSDAAAQKAAEAKAAKLAAEAK
APGADFAALAKANSQDPGSKDAGGDLGWVEKGTMVKPFEDALFSMKAGDVVGPIKSEFGYHVIQLREVKGGQGKSFEQVR
DKLAAEQLKADADKAFADVSGKLVDQLYKNPTALEPAAKQVGLPVQTLGPFSRSDASGVAANPAVLRAAFSETLVQDGTV
SDPINIAPNHSVVLRVTNHTAEQALLLDKVRDKVTAAIRADRAEKAAAAAADALLARVQRGETLQALAASEKLQVQPIPG
LPRTAPIPTPAANRAIFSAPRPTEGKPSFGKVELDGGRFAVFAISKATPGNLKQMPAEQQTMLREQLSQIDGNNAAQTYV
KQMRKRYKIQIEEAQL

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=667, Percent_Identity=27.736131934033, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786238, Length=100, Percent_Identity=39, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71358; Mature: 71358

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKLRDKTSGWIATAILGLLMIPFLFVIDNSYLGGIGANNVAKVQAPPNWWKSAPSWWP
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHCCCCCCC
VSLLWQHHEISTQDFRARFEQARMQERQRQGENFDPRTFESRENKLQVLDQLVDEQVVRL
HHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GAEDAGIVIGDASVRDYIANIQAFQVDGKFSPDKYRAALAQGTPPRTPAQFDALVRDSLQ
CCCCCCEEEECHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QSVIPQAIADSGFATKSEFERLLKLMGETRDVELAMLPPPAMDTAPVSDAQIKQWYDGHT
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
QDFRQPETVTIEYVELNAATMRPATAADEATLRKRYEEEKARFVEPDQRLASHILISAGS
HHCCCCCEEEEEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCC
DAAAQKAAEAKAAKLAAEAKAPGADFAALAKANSQDPGSKDAGGDLGWVEKGTMVKPFED
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
ALFSMKAGDVVGPIKSEFGYHVIQLREVKGGQGKSFEQVRDKLAAEQLKADADKAFADVS
HHHHHCCCCCCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLVDQLYKNPTALEPAAKQVGLPVQTLGPFSRSDASGVAANPAVLRAAFSETLVQDGTV
HHHHHHHHCCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SDPINIAPNHSVVLRVTNHTAEQALLLDKVRDKVTAAIRADRAEKAAAAAADALLARVQR
CCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETLQALAASEKLQVQPIPGLPRTAPIPTPAANRAIFSAPRPTEGKPSFGKVELDGGRFA
CCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEECCCEEE
VFAISKATPGNLKQMPAEQQTMLREQLSQIDGNNAAQTYVKQMRKRYKIQIEEAQL
EEEEECCCCCCHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MLQKLRDKTSGWIATAILGLLMIPFLFVIDNSYLGGIGANNVAKVQAPPNWWKSAPSWWP
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHCCCCCCC
VSLLWQHHEISTQDFRARFEQARMQERQRQGENFDPRTFESRENKLQVLDQLVDEQVVRL
HHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GAEDAGIVIGDASVRDYIANIQAFQVDGKFSPDKYRAALAQGTPPRTPAQFDALVRDSLQ
CCCCCCEEEECHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QSVIPQAIADSGFATKSEFERLLKLMGETRDVELAMLPPPAMDTAPVSDAQIKQWYDGHT
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
QDFRQPETVTIEYVELNAATMRPATAADEATLRKRYEEEKARFVEPDQRLASHILISAGS
HHCCCCCEEEEEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCC
DAAAQKAAEAKAAKLAAEAKAPGADFAALAKANSQDPGSKDAGGDLGWVEKGTMVKPFED
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
ALFSMKAGDVVGPIKSEFGYHVIQLREVKGGQGKSFEQVRDKLAAEQLKADADKAFADVS
HHHHHCCCCCCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKLVDQLYKNPTALEPAAKQVGLPVQTLGPFSRSDASGVAANPAVLRAAFSETLVQDGTV
HHHHHHHHCCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SDPINIAPNHSVVLRVTNHTAEQALLLDKVRDKVTAAIRADRAEKAAAAAADALLARVQR
CCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETLQALAASEKLQVQPIPGLPRTAPIPTPAANRAIFSAPRPTEGKPSFGKVELDGGRFA
CCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEECCCEEE
VFAISKATPGNLKQMPAEQQTMLREQLSQIDGNNAAQTYVKQMRKRYKIQIEEAQL
EEEEECCCCCCHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]