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The map label for this gene is hflC [H]

Identifier: 84622495

GI number: 84622495

Start: 912435

End: 913298

Strand: Direct

Name: hflC [H]

Synonym: XOO_0838

Alternate gene names: 84622495

Gene position: 912435-913298 (Clockwise)

Preceding gene: 84622494

Following gene: 84622496

Centisome position: 18.47

GC content: 63.08

Gene sequence:

>864_bases
ATGAAGAATTCGCTAGTGATCGGCCTGATCGTCGCCGTGCTGCTGACCCTGATGGGCTCGGTGTTCGTGGTGCGCGAAGA
CCAGACCGCCATGGTGCTCAACCTTGGCCGTGTGGTGCGTGCCGACCTCAAGCCCGGCCTGCACTTCAAGATTCCGTTGG
TGGAATCGGTGCGGGTGTTCGATCGCCGCTTCCAGGTACTGGACACCGCCCCGGCGCGTTACTTCACCGCCGAGCAGAAA
GACGTCAGCGTGGACTTCTTCGCCATCGGCTACATCTCCGATGTGCGGGCCTTCTATCGCGCTACCGGTGGTGAGGAGTC
GGTCGCCAACTCGCGTCTGGCCCCGATCATCACCGATTCGCTGCGCAACCAGATCAACTCGCGCACCCTGCAGCAGCTGG
TCTCCGGCGACCGCAGCGAACTGATCGCCAGCCAGCTCAAGGGCATCAATGGCGCCATCAAGGGCCTGGGCATGCAAATC
ACCGACCTGCGCATCAAGCAGATCGATCTGCCGACCGACAGCCAGGTGATCAACGACGTCTACGAACGCATGCGCGCTCA
GCGCAAGCAGGAAGCCAGCAAACTACGCGCCGAAGGCGAAGAGCAGGCCCTGACCATCCGCGCGCAAGCCGACCGCGAGT
CCACCGTGATCGTGGCCGATGCCGAGCGCGACGCGCAGAAGCTGCGCGGCGAAGGCGATGCCGAAGCCGCCCGCATCTAC
GGCCAGGCCGGTTCCAAGGACCCGTCATTCTATGCCTTCTACCGCAGCCTGGAGGCGTACCGCAGTTCCATGACCGACGG
CAATGGCGTGATCGTATTGGACAAGAACGCCCCGTTCCTGCAGTACCTCAAGAGCGATCGCTGA

Upstream 100 bases:

>100_bases
CGCAGGACGTGTTGTTGAATCCGCCGCAAAACACCAGCAGCGAGGCCATCCGTAACCCGGAACGCGGCCCACGCCTAACT
GGCCGTGAGGGAACCGAATA

Downstream 100 bases:

>100_bases
CGGTCCCTCACGAGTGGTCGCCGAGGCGCTCTGCCTGAACGAAAAAACGCCCGCGTCATGTGGGCGTTTTTTATGCGCCA
TTGCGAGCGAGCGCACATGG

Product: integral membrane proteinase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKNSLVIGLIVAVLLTLMGSVFVVREDQTAMVLNLGRVVRADLKPGLHFKIPLVESVRVFDRRFQVLDTAPARYFTAEQK
DVSVDFFAIGYISDVRAFYRATGGEESVANSRLAPIITDSLRNQINSRTLQQLVSGDRSELIASQLKGINGAIKGLGMQI
TDLRIKQIDLPTDSQVINDVYERMRAQRKQEASKLRAEGEEQALTIRAQADRESTVIVADAERDAQKLRGEGDAEAARIY
GQAGSKDPSFYAFYRSLEAYRSSMTDGNGVIVLDKNAPFLQYLKSDR

Sequences:

>Translated_287_residues
MKNSLVIGLIVAVLLTLMGSVFVVREDQTAMVLNLGRVVRADLKPGLHFKIPLVESVRVFDRRFQVLDTAPARYFTAEQK
DVSVDFFAIGYISDVRAFYRATGGEESVANSRLAPIITDSLRNQINSRTLQQLVSGDRSELIASQLKGINGAIKGLGMQI
TDLRIKQIDLPTDSQVINDVYERMRAQRKQEASKLRAEGEEQALTIRAQADRESTVIVADAERDAQKLRGEGDAEAARIY
GQAGSKDPSFYAFYRSLEAYRSSMTDGNGVIVLDKNAPFLQYLKSDR
>Mature_287_residues
MKNSLVIGLIVAVLLTLMGSVFVVREDQTAMVLNLGRVVRADLKPGLHFKIPLVESVRVFDRRFQVLDTAPARYFTAEQK
DVSVDFFAIGYISDVRAFYRATGGEESVANSRLAPIITDSLRNQINSRTLQQLVSGDRSELIASQLKGINGAIKGLGMQI
TDLRIKQIDLPTDSQVINDVYERMRAQRKQEASKLRAEGEEQALTIRAQADRESTVIVADAERDAQKLRGEGDAEAARIY
GQAGSKDPSFYAFYRSLEAYRSSMTDGNGVIVLDKNAPFLQYLKSDR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=312, Percent_Identity=37.1794871794872, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1786697, Length=249, Percent_Identity=24.0963855421687, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI62484448, Length=228, Percent_Identity=28.0701754385965, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24657857, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281365664, Length=230, Percent_Identity=26.9565217391304, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 31897; Mature: 31897

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSLVIGLIVAVLLTLMGSVFVVREDQTAMVLNLGRVVRADLKPGLHFKIPLVESVRVF
CCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHHCCCCCEEECCHHHHHHHH
DRRFQVLDTAPARYFTAEQKDVSVDFFAIGYISDVRAFYRATGGEESVANSRLAPIITDS
HHHHHHHHCCCCHHEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHH
LRNQINSRTLQQLVSGDRSELIASQLKGINGAIKGLGMQITDLRIKQIDLPTDSQVINDV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCEEEEEEEEEEECCCCCHHHHHHH
YERMRAQRKQEASKLRAEGEEQALTIRAQADRESTVIVADAERDAQKLRGEGDAEAARIY
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHCCCCCHHHHHHC
GQAGSKDPSFYAFYRSLEAYRSSMTDGNGVIVLDKNAPFLQYLKSDR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCC
>Mature Secondary Structure
MKNSLVIGLIVAVLLTLMGSVFVVREDQTAMVLNLGRVVRADLKPGLHFKIPLVESVRVF
CCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHHCCCCCEEECCHHHHHHHH
DRRFQVLDTAPARYFTAEQKDVSVDFFAIGYISDVRAFYRATGGEESVANSRLAPIITDS
HHHHHHHHCCCCHHEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHH
LRNQINSRTLQQLVSGDRSELIASQLKGINGAIKGLGMQITDLRIKQIDLPTDSQVINDV
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCEEEEEEEEEEECCCCCHHHHHHH
YERMRAQRKQEASKLRAEGEEQALTIRAQADRESTVIVADAERDAQKLRGEGDAEAARIY
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHCCCCCHHHHHHC
GQAGSKDPSFYAFYRSLEAYRSSMTDGNGVIVLDKNAPFLQYLKSDR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]