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The map label for this gene is fabD [H]

Identifier: 84622462

GI number: 84622462

Start: 874101

End: 875045

Strand: Direct

Name: fabD [H]

Synonym: XOO_0805

Alternate gene names: 84622462

Gene position: 874101-875045 (Clockwise)

Preceding gene: 84622461

Following gene: 84622463

Centisome position: 17.69

GC content: 69.84

Gene sequence:

>945_bases
GTGACCGAATCCACTCTCGCCTTCGTGTTTCCCGGCCAGGGCTCGCAGTCCCTGGGCATGCTGGCCGAACTGTCCGAACT
GCACCCGCAGATTCGCGAAACGTTCGCCGAAGCCTCCGAAGGCGCTGGCGTCGACCTGTGGGCGCTGTCCCAGGGTGGCC
CGGAAGAAATGCTCAACCGCACCGAATACACCCAGCCGGCCTTGCTGGCCGCAGGCGTGGCGGTATGGCGGCTGTGGACT
GCCCAGCGCGGACAGCGTCCGGCGCTGCTGGCCGGGCACAGCCTGGGCGAATACACCGCGCTGGTCGCTGCCGGCGTCTT
GTCGCTTCACGACGGCGCGCATCTGGTGCGGTTGCGCGGCCAGTTCATGCAGGCTGCGGCACCGGCGGGCGTTGGCGCGA
TGGCTGCGGTGCTGGGCGCCGAAGACGCCGTGGTGCTGGAGGTCTGTGCCGAGGCGGCAGGCAGCCAGGTAGTGGTGCCG
GCCAACTTCAATTCGCCCGGCCAGATCGTGATCGGCGGCGATGCCGCAGCGGTGGATCGCGCGCTGGCGCTGCTGGCCGA
GCGCGGCGTGCGCAAGGCGGTCAAGCTGGCGGTGAGCGTGCCCTCGCACACCCCGTTGATGCGCGATGCCGCCAACCAGC
TGGGCGAGGCGATGGCAGGGTTGAGCTGGCATGCTCCGCAGATTCCGGTGGTGCAGAACGTGGACGCGCGCGTACACGAC
GGCAGCGCAGCCATCCGCCAGGCACTGGTGGAGCAGCTATATCTGCCGGTGCAGTGGACCGGTTGCGTGCAGGCGCTCGC
CAGCCAGGGCATCACCCGGATCGCCGAATGCGGCCCGGGCAAGGTGCTGAGCGGGCTGATCAAGCGCATCGACAAGAGCC
TGGACGCGCGCCCGCTGGCCACGCCTGCCGATTATGCCGGCGCGCTCGACGCGTGGGCCCACTGA

Upstream 100 bases:

>100_bases
CGTTGGAAGCTGCTCTGTTGGCTCCTGCATACGCGGCAGTACAGACGCCACGGCGATTTCGCACGTATGATCCCGGCTCG
ATTTTTGTAGGCAGCAACGC

Downstream 100 bases:

>100_bases
TCCAACGCCGCTGCCGGTTGTGCCGGCATCCCTCGACGTTCGCGGCCGCGGTTGCGACGTCCCCTTTCGAGGAACAGCAT
TCATGAGCAAGCCCCTGCAG

Product: malonyl CoA-ACP transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWT
AQRGQRPALLAGHSLGEYTALVAAGVLSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVP
ANFNSPGQIVIGGDAAAVDRALALLAERGVRKAVKLAVSVPSHTPLMRDAANQLGEAMAGLSWHAPQIPVVQNVDARVHD
GSAAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH

Sequences:

>Translated_314_residues
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWT
AQRGQRPALLAGHSLGEYTALVAAGVLSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVP
ANFNSPGQIVIGGDAAAVDRALALLAERGVRKAVKLAVSVPSHTPLMRDAANQLGEAMAGLSWHAPQIPVVQNVDARVHD
GSAAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH
>Mature_313_residues
TESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNRTEYTQPALLAAGVAVWRLWTA
QRGQRPALLAGHSLGEYTALVAAGVLSLHDGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVPA
NFNSPGQIVIGGDAAAVDRALALLAERGVRKAVKLAVSVPSHTPLMRDAANQLGEAMAGLSWHAPQIPVVQNVDARVHDG
SAAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLATPADYAGALDAWAH

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=32.013201320132, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI27477045, Length=113, Percent_Identity=40.7079646017699, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=54.071661237785, Blast_Score=322, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71984332, Length=299, Percent_Identity=29.7658862876254, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.1525423728814, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24665753, Length=307, Percent_Identity=32.8990228013029, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32617; Mature: 32485

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
TEYTQPALLAAGVAVWRLWTAQRGQRPALLAGHSLGEYTALVAAGVLSLHDGAHLVRLRG
HCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVPANFNSPGQIVIGGDAAAVDR
HHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHH
ALALLAERGVRKAVKLAVSVPSHTPLMRDAANQLGEAMAGLSWHAPQIPVVQNVDARVHD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
GSAAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
TPADYAGALDAWAH
CCHHHHHHHHHCCC
>Mature Secondary Structure 
TESTLAFVFPGQGSQSLGMLAELSELHPQIRETFAEASEGAGVDLWALSQGGPEEMLNR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
TEYTQPALLAAGVAVWRLWTAQRGQRPALLAGHSLGEYTALVAAGVLSLHDGAHLVRLRG
HCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
QFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVPANFNSPGQIVIGGDAAAVDR
HHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCHHHHHH
ALALLAERGVRKAVKLAVSVPSHTPLMRDAANQLGEAMAGLSWHAPQIPVVQNVDARVHD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
GSAAIRQALVEQLYLPVQWTGCVQALASQGITRIAECGPGKVLSGLIKRIDKSLDARPLA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
TPADYAGALDAWAH
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]