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The map label for this gene is fabH [H]

Identifier: 84622460

GI number: 84622460

Start: 872176

End: 873153

Strand: Direct

Name: fabH [H]

Synonym: XOO_0803

Alternate gene names: 84622460

Gene position: 872176-873153 (Clockwise)

Preceding gene: 84622459

Following gene: 84622461

Centisome position: 17.65

GC content: 62.37

Gene sequence:

>978_bases
ATGAGCAAGCGGATCTATTCCAGAATCGCGGGCACGGGTAGCTATTTGCCCGAAAAGGTGTTGACCAACGACGACATGTC
GAAGATCGTCGACACCAGCGATGAGTGGATCTTCTCGCGCACTGGTATTCGTGAACGTCACATCGCTGCCGACGACCAGG
CCACCAGCGACCTGGCGTATTTCGCCTCGCTGAAGGCGATGGAAGCGGCCGGTGTGACTGCCGACGAGATCGATCTGATC
GTCATCGGCACCACCACCCCGGACCTGATATTTCCGTCGACCGCCTGTCTGCTGCAGGCGCGGCTGGGCAACGTCGGTTG
CGGTGCAATGGACGTCAACGCTGCCTGTTCGGGGTTTGTCTACGCGCTTAGCGTGGCCGACAAGTTCGTGCGCAGCGGCG
ACGCCAAGACCGTGCTGGTGGTTGGCGCAGAAACGCTGACCCGCATCCTCGACTGGACCGACCGCACCACCTGCGTGCTA
TTCGGCGATGGTGCCGGCGCGGTGATCCTCAAGGCCGACGAAGAGACCGGTATTCTCAGCACCCACTTGCGTGCCGATGG
CAGCAAGAAAGAGCTGCTGTGGGATCCGGTTGGCGTGTCGGTTGGCTTCGGTGAAGGCAAGAATGGCGGCGGCGCGTTGC
TGATGAAAGGCAACGACGTCTTCAAATACGCGGTCAAGGCGCTGAACTCGGTGGTCGATGAGACTCTGGCGGCCAACGGC
TACGACGCGCACGACCTGGATTGGCTGATTCCACATCAGGCCAATCTGCGCATCATCGAAGCCACCGCCAAGCGGCTGGA
CCTGCCGATGGAGCAAGTGGTGGTCACCGTGGATCGCCACGGCAATACTTCCTCGGCGTCGGTGCCGCTGGCATTGGACG
AAGCGGTGCGCTCGGGTCGCGTGCAGCGCGGCCAGTTGCTGCTGCTGGAAGCCTTCGGCGGCGGGTTTGCCTGGGGCTCG
GCGCTGTTGCGCTACTGA

Upstream 100 bases:

>100_bases
AAGAAGATTGATCCGTGGCGCCCGCCGCGTTCGACGCGGCCGGGTGATCTCGCTTCTTCCGGAGCCGCAGGTCACCGCGG
CTCTTGCAACAGGGAACAGT

Downstream 100 bases:

>100_bases
GGTCGTTGTCTCCTGCATCGGGCAGGCGAACGCGGCCGCCCAGTCGCGTTCGTGCCTCGCGGTCGATGCGCCTGGCGCAT
TGGGATGGCGGCATCCTGTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAYFASLKAMEAAGVTADEIDLI
VIGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVL
FGDGAGAVILKADEETGILSTHLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANG
YDAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGRVQRGQLLLLEAFGGGFAWGS
ALLRY

Sequences:

>Translated_325_residues
MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAYFASLKAMEAAGVTADEIDLI
VIGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVL
FGDGAGAVILKADEETGILSTHLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANG
YDAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGRVQRGQLLLLEAFGGGFAWGS
ALLRY
>Mature_324_residues
SKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAYFASLKAMEAAGVTADEIDLIV
IGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVLF
GDGAGAVILKADEETGILSTHLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANGY
DAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGRVQRGQLLLLEAFGGGFAWGSA
LLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=60.1246105919003, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34658; Mature: 34527

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAY
CCHHHHHHHCCCCCCCCHHHCCCCCHHHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHH
FASLKAMEAAGVTADEIDLIVIGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFV
HHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCHHHHHHH
YALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVLFGDGAGAVILKADEETGILS
HHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEE
THLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANG
EEEECCCCCCCEEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
YDAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGR
CCCCCCCEECCCCCCEEEEEEHHHHHCCCHHHEEEEEECCCCCCCCCCCEEHHHHHHCCC
VQRGQLLLLEAFGGGFAWGSALLRY
CCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAY
CHHHHHHHCCCCCCCCHHHCCCCCHHHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHH
FASLKAMEAAGVTADEIDLIVIGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFV
HHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCHHHHHHH
YALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVLFGDGAGAVILKADEETGILS
HHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEE
THLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANG
EEEECCCCCCCEEECCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
YDAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGR
CCCCCCCEECCCCCCEEEEEEHHHHHCCCHHHEEEEEECCCCCCCCCCCEEHHHHHHCCC
VQRGQLLLLEAFGGGFAWGSALLRY
CCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]