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The map label for this gene is atpA [H]

Identifier: 84622323

GI number: 84622323

Start: 716933

End: 718480

Strand: Direct

Name: atpA [H]

Synonym: XOO_0666

Alternate gene names: 84622323

Gene position: 716933-718480 (Clockwise)

Preceding gene: 84622322

Following gene: 84622324

Centisome position: 14.51

GC content: 63.82

Gene sequence:

>1548_bases
ATGGCAACCACGCTCAACCCCTCCGAAATCAGCGACCTGATCAAGACCCGCATCGAAGCGGTCAAGCTGTCCGCAGAGTC
GCGCAACGAAGGCTCCGTGACCAGCGTGTCCGACGGCATCGTGCGCATCTTCGGCCTGGCCGACGTGATGCAGGGCGAAA
TGATCGAACTGCCGAACAACACCTTCGCGCTGGCACTGAACCTGGAGCGCGATTCGGTCGGCGCCGTGGTGCTGGGCGAT
TACGAAAACCTGCGCGAAGGCGACGTGGCCAAGACCACCGGCCGCATCCTGGAAGTGCCGGTGGGTCCGGAACTGCTGGG
TCGCGTGGTCAACGCACTGGGCGAGCCGATCGACGGCAAGGGTCCGCTGGGCGCCACCCAGACCGCACCGGTGGAGCGCG
TTGCGCCCGGCGTGATCTGGCGTAAGTCGGTCGACCAGCCGGTGCAGACCGGTTACAAGTCGGTCGATGCGATGATCCCG
ATCGGCCGTGGCCAGCGTGAGTTGGTCATCGGCGACCGTCAGACCGGCAAGACCGCGTTGGCGATCGATGCGGTGATCAA
CCAGAAGGGCACCGGTATCAAGTGCGTGTACGTGGCGATCGGTCAGAAGGCCTCGACCGTTGCCAACATCGTGCGCAAGC
TGGAAGAAAACGGCGCGCTGGCGCACACCGTGGTGGTGGCTGCGACCGCGTCCGAATCGGCCGCGATGCAGTACATCAGT
CCGTACGCCGGTTGCACCATGGGCGAATACTTCATGGACCGCGGCGAAGACGCGCTGATCGTGTACGACGATCTGTCCAA
GCAGGCTGTGGCCTACCGCCAGATCTCGCTGCTGCTCAAGCGTCCGCCGGGTCGCGAAGCCTATCCGGGCGACGTGTTCT
ATCTGCACTCCCGCCTGCTGGAGCGTGCAGCGCGCGTGTCCGAGGACTACGTGGAGAAGTTCACCAACGGTGCGGTGACC
GGCAAGACCGGTTCGCTGACCGCGCTGCCGATCATCGAAACGCAGGCCGGCGATGTGTCCGCGTTCGTGCCGACCAACGT
GATCTCGATCACCGACGGCCAGATATTCCTGGAAACCGACCTGTTCAACGCCGGTATCCGCCCGGCCGTGAACGCCGGTA
TTTCGGTGTCGCGCGTCGGTGGTGCAGCCCAGACCAAGATCATCAAGAAGCTGTCCGGCGGCATCCGTATCTCGCTGGCG
CAGTACCGCGAGCTGGCGGCGTTCGCGCAGTTCGCCTCGGACCTGGACGAAGCCACCCGCAAGCAGCTCGAGCGCGGTCA
GCGCGTCACCGAACTGATGAAGCAGAAGCAGTACGCGCCGATGTCCATCGCCAACCAGGCGCTGTCGATCTACGCCGTCA
ACGAGGGTTACCTCGACGACGTGCCGGTCAACAAGCTGCTGGCGTTCGAAGAAGGCCTGCACGCGCACTTCGCCAACACC
CAGGGCGAACTGGTCTCCAAGATCAACAGCACCGGCGGTTGGGACAACGACATCGAAGCCAGCTTCAAGAAGGGCATCCA
AGAGTTCAAGACCACGGGCACCTGGTAA

Upstream 100 bases:

>100_bases
ACGGCTCGCTGAAGGGCAAGCTTGCGCGTCTGCAAAGCTCGCTCGCCCACTGAATTCACATAAACGCACGGCCCCCGCGG
CCGGCACCTAGGACTGAACG

Downstream 100 bases:

>100_bases
GGGCGCCGGGATTCGGGATTGGGCATTCGGAATTTGCAGAAGCGGTGGTTCGGGGCGTTGGCTGATGCCCAGCCCCGCTT
CTGTTTCCCAGACGTTAGGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGD
YENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIP
IGRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYIS
PYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEDYVEKFTNGAVT
GKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLA
QYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANT
QGELVSKINSTGGWDNDIEASFKKGIQEFKTTGTW

Sequences:

>Translated_515_residues
MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGD
YENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIP
IGRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYIS
PYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEDYVEKFTNGAVT
GKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLA
QYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANT
QGELVSKINSTGGWDNDIEASFKKGIQEFKTTGTW
>Mature_514_residues
ATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGDY
ENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPI
GRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYISP
YAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEDYVEKFTNGAVTG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQ
YRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANTQ
GELVSKINSTGGWDNDIEASFKKGIQEFKTTGTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=55.4901960784314, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=55.4901960784314, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI19913426, Length=317, Percent_Identity=27.4447949526814, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913428, Length=317, Percent_Identity=27.4447949526814, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI32189394, Length=324, Percent_Identity=27.1604938271605, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913424, Length=337, Percent_Identity=26.1127596439169, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=73.385518590998, Blast_Score=776, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=363, Percent_Identity=26.7217630853994, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790170, Length=433, Percent_Identity=23.5565819861432, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=513, Percent_Identity=54.775828460039, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=513, Percent_Identity=54.775828460039, Blast_Score=561, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=50.8771929824561, Blast_Score=507, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17570191, Length=317, Percent_Identity=27.7602523659306, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=353, Percent_Identity=27.1954674220963, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=441, Percent_Identity=23.1292517006803, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=265, Percent_Identity=27.1698113207547, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=52, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=519, Percent_Identity=52.4084778420039, Blast_Score=557, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6319603, Length=323, Percent_Identity=29.1021671826625, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=25.2699784017279, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24658560, Length=520, Percent_Identity=55.1923076923077, Blast_Score=570, Evalue=1e-163,
Organism=Drosophila melanogaster, GI281361666, Length=309, Percent_Identity=27.831715210356, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646341, Length=309, Percent_Identity=27.831715210356, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136796, Length=309, Percent_Identity=27.831715210356, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24638766, Length=392, Percent_Identity=24.7448979591837, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574560, Length=429, Percent_Identity=23.5431235431235, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583992, Length=337, Percent_Identity=25.2225519287834, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583988, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583986, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583984, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129479, Length=336, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55312; Mature: 55180

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNN
CCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEECCCCHHHHHHHHHHHCCCEEECCCC
TFALALNLERDSVGAVVLGDYENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGK
EEEEEEEECCCCCCEEEECCCCCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHCCCCCCC
GPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTAL
CCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCCEEE
AIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYIS
EEEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHC
PYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLL
CCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERAARVSEDYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETD
HHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEC
LFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATR
CCCCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANT
HHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHCCC
QGELVSKINSTGGWDNDIEASFKKGIQEFKTTGTW
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNN
CCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEECCCCHHHHHHHHHHHCCCEEECCCC
TFALALNLERDSVGAVVLGDYENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGK
EEEEEEEECCCCCCEEEECCCCCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHCCCCCCC
GPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTAL
CCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCCEEE
AIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYIS
EEEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHC
PYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLL
CCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERAARVSEDYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETD
HHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEC
LFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATR
CCCCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANT
HHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHCCC
QGELVSKINSTGGWDNDIEASFKKGIQEFKTTGTW
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA