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The map label for this gene is atpB [H]

Identifier: 84622319

GI number: 84622319

Start: 714594

End: 715394

Strand: Direct

Name: atpB [H]

Synonym: XOO_0662

Alternate gene names: 84622319

Gene position: 714594-715394 (Clockwise)

Preceding gene: 84622318

Following gene: 84622320

Centisome position: 14.46

GC content: 59.8

Gene sequence:

>801_bases
ATGGCGGGCGAGGCAGCAACACCTACCTCCTATATCCAGCATCACTTGCACAACCTGATCCTTCCGGTTCGCGATGGTGG
CGGCACGTTTTGGACCATCCACCTCGACACCCTGATCATGGCGGTGTTGATGGGGTTGGTCATGGTCCTGGCGTTCTGGA
CGGCGACCCGGAATGCCACCTCCGGCGTACCAGGCAAGTGGCAGGCGTTCGTGGAAATCTGCCTGGAGTTCGTCGACCGC
CAGGCCAAGGACACCTATCACGGCAGCAGCAAGCTGGTGACGCCGATCGCGATCACCATCTTCTTCTGGATCCTGTTGAT
GAACCTCATCAAGATGATCCCGGCCGATTTCATCGCCATCCCGCTGAGCTGGGTCGGCGTGCACGCCTGGAAGCCGGTGC
CCACTGCCGACGTCAATGCCACCTTGGGCATGTCGATCAGCGTGTTCTTCCTGATGATCGTGTTCTCGCTGCGCTCCAAG
GGCGTGGGCGGCATGACCAAGGAATTCCTCACGGCGCCGTTCGGCAAATGGATGATGCCGTTCAACCTGCTTTTGAACAT
CGTCGAGTGGCTGAGCAAGCCGATTTCGTTGGCGATGCGACTGTTCGGCAACATGTTCGGCGGCGAGATCGTCTTCCTGC
TGATCTGGGTGCTGGGCGGTGCGGGCATCGCCGGCATGGTCGCTGGCGGCGTATTCGGCCTTGGCTGGATGCTGTTCCAC
CTGCTGGTGATTCCGCTGCAGGCCTTCATTTTCATGATGCTGTCGATCGTGTATCTGAGCCTGGCCGAAGACAGCCACTG
A

Upstream 100 bases:

>100_bases
CTGCCTCCTCTGGCTTTGTTGGCAGGTATCGCCATCGGGCTGATTTTTCAGGTTCTGGCTCTGGCCAGACGCTGATTCGA
ACTTAAAGGGCTCCGGACAC

Downstream 100 bases:

>100_bases
GTTTGCGTCACCCTTCATCTGCTTCATTCCGCTTCATCCATCACCCTTAGAAACTTTCGTTCGGAGATCACCATGAACCT
CGCCGTCCTGACCAACCTCG

Product: F0F1 ATP synthase subunit A

Products: ATP; H+; H2O [C]

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MAGEAATPTSYIQHHLHNLILPVRDGGGTFWTIHLDTLIMAVLMGLVMVLAFWTATRNATSGVPGKWQAFVEICLEFVDR
QAKDTYHGSSKLVTPIAITIFFWILLMNLIKMIPADFIAIPLSWVGVHAWKPVPTADVNATLGMSISVFFLMIVFSLRSK
GVGGMTKEFLTAPFGKWMMPFNLLLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGIAGMVAGGVFGLGWMLFH
LLVIPLQAFIFMMLSIVYLSLAEDSH

Sequences:

>Translated_266_residues
MAGEAATPTSYIQHHLHNLILPVRDGGGTFWTIHLDTLIMAVLMGLVMVLAFWTATRNATSGVPGKWQAFVEICLEFVDR
QAKDTYHGSSKLVTPIAITIFFWILLMNLIKMIPADFIAIPLSWVGVHAWKPVPTADVNATLGMSISVFFLMIVFSLRSK
GVGGMTKEFLTAPFGKWMMPFNLLLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGIAGMVAGGVFGLGWMLFH
LLVIPLQAFIFMMLSIVYLSLAEDSH
>Mature_265_residues
AGEAATPTSYIQHHLHNLILPVRDGGGTFWTIHLDTLIMAVLMGLVMVLAFWTATRNATSGVPGKWQAFVEICLEFVDRQ
AKDTYHGSSKLVTPIAITIFFWILLMNLIKMIPADFIAIPLSWVGVHAWKPVPTADVNATLGMSISVFFLMIVFSLRSKG
VGGMTKEFLTAPFGKWMMPFNLLLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGIAGMVAGGVFGLGWMLFHL
LVIPLQAFIFMMLSIVYLSLAEDSH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=276, Percent_Identity=45.6521739130435, Blast_Score=231, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14 [C]

Molecular weight: Translated: 29335; Mature: 29203

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEAATPTSYIQHHLHNLILPVRDGGGTFWTIHLDTLIMAVLMGLVMVLAFWTATRNAT
CCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
SGVPGKWQAFVEICLEFVDRQAKDTYHGSSKLVTPIAITIFFWILLMNLIKMIPADFIAI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
PLSWVGVHAWKPVPTADVNATLGMSISVFFLMIVFSLRSKGVGGMTKEFLTAPFGKWMMP
HHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHH
FNLLLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGIAGMVAGGVFGLGWMLFH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVIPLQAFIFMMLSIVYLSLAEDSH
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGEAATPTSYIQHHLHNLILPVRDGGGTFWTIHLDTLIMAVLMGLVMVLAFWTATRNAT
CCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
SGVPGKWQAFVEICLEFVDRQAKDTYHGSSKLVTPIAITIFFWILLMNLIKMIPADFIAI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
PLSWVGVHAWKPVPTADVNATLGMSISVFFLMIVFSLRSKGVGGMTKEFLTAPFGKWMMP
HHHHHHHHCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHH
FNLLLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGIAGMVAGGVFGLGWMLFH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVIPLQAFIFMMLSIVYLSLAEDSH
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP; H+; Phosphate [C]

Specific reaction: ADP + (4) H+ + Phosphate <==> ATP + (3) H+ + H2O [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]