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The map label for this gene is evgS [H]

Identifier: 84622292

GI number: 84622292

Start: 687995

End: 689890

Strand: Direct

Name: evgS [H]

Synonym: XOO_0635

Alternate gene names: 84622292

Gene position: 687995-689890 (Clockwise)

Preceding gene: 84622291

Following gene: 84622293

Centisome position: 13.93

GC content: 64.03

Gene sequence:

>1896_bases
ATGGTGTTCGACGGTGAGCAGGCGGTGGATTATCTGATCCGTACCACCAATGGCGCGTTCGAGCGCTACACCGGTCTGTC
CACCAACGCACTGAACATTTCCATTCGCGACCTGCTCCCTGAGCATGAGCAGGAGTGGTTCGACCGCTACGGCCTTGTTG
CCCGCACAGGCAACCGCATCCACTTTGAAATGCAGGCCAAGGCGCTCAAGCGCTGGTATTCGGTCGATGCGTTCCGCGTC
GGGCGGCCGGACCAGGGGCGGGTGGCTGTCTTGTTCATGGACATTACCGAGCGCAAGCGTGTCGAGCGTGAGCTGGCCGA
AAGCGAGGCGCGTTTCAGTGCGCTGGCCGACGGGTTGCCGATGCCGGTGTGGGTGCTGGACGCGCAGGGCGTGGTGCGCT
TCGTCAACAGCGCGTACGGCGAATTCTTCGGCCTGGATATTTCCAGCGGCACGGTATCGGCGTGGAGCGAATTGCTGCAT
CCCGACGATTTGCCGACGTTTCAATTCGAGCTGGCGGCATCGCTGCAGGAACAACGCGGCCTGCGCGCACTGGTGCGTGC
ACGCCGCCATGATGGACAGTGGCGCTGGATCGAGATGACTGCCACGCCGCGCTATTCGGCCGATGGCCGGTTCATCGGCC
TGGCCGGGAGCAGCCCGGATGTGACCGAGCAGCGCGAGATCGAGCTGGCGCGCGAGCAATTGCTCGAATCCGAGCGCAGC
GCGCGCAACGAGGCCGAAAGCATGGCGCGGCTGAAGGACGAGTTCCTGGCCACGCTCTCGCACGAATTGCGCACCCCGCT
GACCACCATCCTGGGCTGGAGCGAATTGCTGCTGCAGCGGGTGGAAGAAGGACACACCACCTACAAGGGCTTGTCGGTCA
TCGCCAGCAGCGCACGCGCGCAGAAGCGACTGATTTCCGACATGCTCGATCTCAGCAGCATGTTGTTGGGCAAGGTGCAG
CTGGAAGTCGAATCGCTGGACCTGGCCGAGCAGGTGCGCGAAGCCTTGAACACCCAGGAACTGGCCGCCGAAGGCAAGGA
CCAGATACTGAAACTGCATGTGCCGCCCACGCCATGCCTGGTGCTTGGCGATGCCACGCGCCTGCAGCAGGTGGTATGGA
ATCTGCTTTCCAACGCGATCAAGTTCACCCCGGCGCATGGCCGTATCGACGTCAGTATCGAGCGCGACGACGGGCATCTG
GTGGTGTCGGTCTGCGACTCCGGCGACGGCATTGCAGCCGAATTTCTGCCGCATCTGTTCGGACGTTTCCGTCAAGCCGA
TGGCACGACCACGCGCCAGCATGGCGGTTTGGGTCTTGGCCTGGCGATCGTGCAACAGCTGGTTGAAATGCACGGCGGCC
AGGTCGGTGCCACCAGCGGCGGCCGCGGCAAGGGTGCGACCTTCACCGTGCGCTTGCCCGAACATATTCCCGATCAAGCC
AAGCGTCCGCGTCGCGAATTGCGGCGGCGGCTGATGTCCGAACAGATTGTCGAGGCGCGCGCGCTCAACGGTCTGCGCCT
GCTGGCGGTCGAAGACCAACCGGACATGCTCGATTATCTGCGGCGTTTGCTCGAAGAGCAGGGCGCCGAGGTGGTCACCG
CCGGCAGCGCCACCGACGCATTGGCCTTGCTCGATCATCGCGGCCACGCCCGCTTCGATCTGATGCTCACCGATATCGGC
ATGCCCGGCATGGACGGCTACGGGTTGATCCGCACTGTGCGCGAAAACCTCGGACTGGATGCAACCGCGCTGCCGGCCGT
GGCGGTGACCGCGCTGGCCCGCGAAGACGACCGCAATCGCGCGCTGGAGTCCGGGTTTCAAGAGCATCTCGCAAAGCCGT
ATAGCGTGGCGCAGTTGGTTGCTGCCGTGCGTGCTGCGCGCGACGCTGTGGAGTAA

Upstream 100 bases:

>100_bases
GGCTGCCGCCCTGCCGGCCGCCATCGCCGAGCCGTTTCTCGACCCGGCGATGTATCACGAAATCTTCCACAACATCGATG
CCGGTTTCTGCGTCATCGAC

Downstream 100 bases:

>100_bases
CGCGTGTACGACGTTATTGCCGCGCGTGGGAGGTGTATTGGCCAGTGGGCTACGGCCACACCGTCGGATGCTTGCAGCAG
GTCATCCGGATCAGGCGTGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MVFDGEQAVDYLIRTTNGAFERYTGLSTNALNISIRDLLPEHEQEWFDRYGLVARTGNRIHFEMQAKALKRWYSVDAFRV
GRPDQGRVAVLFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGHTTYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLAEQVREALNTQELAAEGKDQILKLHVPPTPCLVLGDATRLQQVVWNLLSNAIKFTPAHGRIDVSIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALLDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRNRALESGFQEHLAKPYSVAQLVAAVRAARDAVE

Sequences:

>Translated_631_residues
MVFDGEQAVDYLIRTTNGAFERYTGLSTNALNISIRDLLPEHEQEWFDRYGLVARTGNRIHFEMQAKALKRWYSVDAFRV
GRPDQGRVAVLFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGHTTYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLAEQVREALNTQELAAEGKDQILKLHVPPTPCLVLGDATRLQQVVWNLLSNAIKFTPAHGRIDVSIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALLDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRNRALESGFQEHLAKPYSVAQLVAAVRAARDAVE
>Mature_631_residues
MVFDGEQAVDYLIRTTNGAFERYTGLSTNALNISIRDLLPEHEQEWFDRYGLVARTGNRIHFEMQAKALKRWYSVDAFRV
GRPDQGRVAVLFMDITERKRVERELAESEARFSALADGLPMPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLH
PDDLPTFQFELAASLQEQRGLRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGHTTYKGLSVIASSARAQKRLISDMLDLSSMLLGKVQ
LEVESLDLAEQVREALNTQELAAEGKDQILKLHVPPTPCLVLGDATRLQQVVWNLLSNAIKFTPAHGRIDVSIERDDGHL
VVSVCDSGDGIAAEFLPHLFGRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQA
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDALALLDHRGHARFDLMLTDIG
MPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRNRALESGFQEHLAKPYSVAQLVAAVRAARDAVE

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=547, Percent_Identity=29.2504570383912, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI48994928, Length=559, Percent_Identity=29.8747763864043, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI87081816, Length=345, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=38.4615384615385, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=36.6935483870968, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=33.4677419354839, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=32.156862745098, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786600, Length=413, Percent_Identity=27.6029055690073, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=31.5573770491803, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=30.6201550387597, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=30.7017543859649, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790861, Length=230, Percent_Identity=31.304347826087, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=27.9279279279279, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=29.7202797202797, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=268, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=33.0578512396694, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=224, Percent_Identity=28.125, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=27.8969957081545, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=151, Percent_Identity=31.7880794701987, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70076; Mature: 70076

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFDGEQAVDYLIRTTNGAFERYTGLSTNALNISIRDLLPEHEQEWFDRYGLVARTGNRI
CCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHCCCEEECCCEE
HFEMQAKALKRWYSVDAFRVGRPDQGRVAVLFMDITERKRVERELAESEARFSALADGLP
EEEHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
MPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRG
CCEEEECHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGHTTYKGLSVIASSARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKRLISDMLDLSSMLLGKVQLEVESLDLAEQVREALNTQELAAEGKDQILKLHVPPTPCL
HHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEE
VLGDATRLQQVVWNLLSNAIKFTPAHGRIDVSIERDDGHLVVSVCDSGDGIAAEFLPHLF
EECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
GRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHH
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHH
LALLDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRNR
HHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
ALESGFQEHLAKPYSVAQLVAAVRAARDAVE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFDGEQAVDYLIRTTNGAFERYTGLSTNALNISIRDLLPEHEQEWFDRYGLVARTGNRI
CCCCHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHCCCEEECCCEE
HFEMQAKALKRWYSVDAFRVGRPDQGRVAVLFMDITERKRVERELAESEARFSALADGLP
EEEHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
MPVWVLDAQGVVRFVNSAYGEFFGLDISSGTVSAWSELLHPDDLPTFQFELAASLQEQRG
CCEEEECHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LRALVRARRHDGQWRWIEMTATPRYSADGRFIGLAGSSPDVTEQREIELAREQLLESERS
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ARNEAESMARLKDEFLATLSHELRTPLTTILGWSELLLQRVEEGHTTYKGLSVIASSARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKRLISDMLDLSSMLLGKVQLEVESLDLAEQVREALNTQELAAEGKDQILKLHVPPTPCL
HHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCEE
VLGDATRLQQVVWNLLSNAIKFTPAHGRIDVSIERDDGHLVVSVCDSGDGIAAEFLPHLF
EECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
GRFRQADGTTTRQHGGLGLGLAIVQQLVEMHGGQVGATSGGRGKGATFTVRLPEHIPDQA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCCHH
KRPRRELRRRLMSEQIVEARALNGLRLLAVEDQPDMLDYLRRLLEEQGAEVVTAGSATDA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHH
LALLDHRGHARFDLMLTDIGMPGMDGYGLIRTVRENLGLDATALPAVAVTALAREDDRNR
HHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHH
ALESGFQEHLAKPYSVAQLVAAVRAARDAVE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]