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The map label for this gene is ntrC [H]

Identifier: 84622247

GI number: 84622247

Start: 640302

End: 641582

Strand: Direct

Name: ntrC [H]

Synonym: XOO_0590

Alternate gene names: 84622247

Gene position: 640302-641582 (Clockwise)

Preceding gene: 84622241

Following gene: 84622248

Centisome position: 12.96

GC content: 63.39

Gene sequence:

>1281_bases
ATGGACCGTCTTTCCTGCGCCATCATCGACGACGACGTGGAGTTCTGCGATCAGGTGGTTGAACTCGCCACCGATAGCGG
CTTCCGTGCTAAGGGCATCCACACCCTTGGCGAAGCCAGCCGCTGGCTGGACAGTAACTTTCCCGACCTGTTGGTGGTGG
ATGTTGGCCTGCCAGACGGCAGCGGTTTCGATCTGATCGAACGGCTCGACCCGGATCACACTCCACAGATCGTCGTGGTG
TCGGGCGATTACGCGCGTGAAACCCAGGGCCGTGCGCAGCAGTTCGGGGTCAGCGAATTCTTGACCAAGCCATTTGCGCC
GGAACGCCTGGAGCGTGTGCTTGGCGGACTGCGCGAAGCGCAACAAGGCAACCTGGGCATCGTTGGCAAAAGCGACAGCA
TCGTGATGCTGCGCAAGGACATCGTGCGCGTCGCGCCGACCGATCTGAATGTGTTGGTCACCGGCGAAACCGGCACCGGC
AAGGATCTGGTCGCGCGCGCCATCCATCGCGTGTCCGGCCGCAGCGGCCGCTTCGTGCCGGTCAACTGCGGCGCCATTCC
AGAGGAGTTGCTGGCCAGCCAGTTGTTCGGCCACGAGCGCGGCAGCTTCACCGGTGCCGACCGTCGGCACGCCGGGTTCC
TGGAGCAGGCGGCAGGCGGCACGCTGTTCCTGGACGAAATTGGCGAAATGCCAAAGCGGTTGCAGGTGTATCTGCTGCGG
GCGATCGAATCGCGCAGTTTCATGCGCGTGGGCGGCAACGAAGAAATCGTACTGGACGCGCGCGTGGTGGCAGCGACGCA
TCAGCATGTGCAGCGCGAGCAGGCGGTGCTGCGCGAAGACCTGTTCTACCGTCTCAACGAATACCCGATTCAGGTGCCGC
CGTTGCGCGAGCGCCGTGGCGATGCGCGCCTGCTCGGGCTGCGCGTGATCGACGAGCTCAACGTCAAGTATGGCAAACGC
AAGTTGCCGACCAAGTCGCTGCTGCGTTATCTGGCGTGCCACGTCTGGCCGGGCAACGTGCGCGAGTTGCGCTCGTTTAT
CCACTATCTGTATCTGCGTTCCGATGGCGATCTGTTGAGCGCACCGGATGTGGAGCAGGCCGTACCGCAGGCCGACGAAG
ACGGCTTGCTGATTCCTGCTGGCTGGACCATGCGCCAGGCCGAAGACGCCATGATCGAATCGGCACTGGCACGCACGCGC
TTCAACAAGAAGGCCGCGGCGCGTGAACTGGGTATCAGCGTGCGCACCCTGCACAACCGGCTCAGCGACAAGGATGCGTA
G

Upstream 100 bases:

>100_bases
GTGACCGCATGCAACTTCCGAGGTGGTGTGTCAGTGCACTTCGCGCGGCCGTCACAATTTTCAATTGAACATGTAACAGT
CATTGCGGACAGAAGCGCTC

Downstream 100 bases:

>100_bases
TGACTGACGCACCGCGTGGGCAGCGGCGCGAGCTGCTGCACGAGTTGCGCAACCGGCTCAATGTGATGGGCTTTGCGTTG
TACGCATTGCGTAACGAAAC

Product: NtrC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDRLSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVV
SGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGKSDSIVMLRKDIVRVAPTDLNVLVTGETGTG
KDLVARAIHRVSGRSGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLR
AIESRSFMRVGGNEEIVLDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKR
KLPTKSLLRYLACHVWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQAVPQADEDGLLIPAGWTMRQAEDAMIESALARTR
FNKKAAARELGISVRTLHNRLSDKDA

Sequences:

>Translated_426_residues
MDRLSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVV
SGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGKSDSIVMLRKDIVRVAPTDLNVLVTGETGTG
KDLVARAIHRVSGRSGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLR
AIESRSFMRVGGNEEIVLDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKR
KLPTKSLLRYLACHVWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQAVPQADEDGLLIPAGWTMRQAEDAMIESALARTR
FNKKAAARELGISVRTLHNRLSDKDA
>Mature_426_residues
MDRLSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDGSGFDLIERLDPDHTPQIVVV
SGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREAQQGNLGIVGKSDSIVMLRKDIVRVAPTDLNVLVTGETGTG
KDLVARAIHRVSGRSGRFVPVNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLR
AIESRSFMRVGGNEEIVLDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRGDARLLGLRVIDELNVKYGKR
KLPTKSLLRYLACHVWPGNVRELRSFIHYLYLRSDGDLLSAPDVEQAVPQADEDGLLIPAGWTMRQAEDAMIESALARTR
FNKKAAARELGISVRTLHNRLSDKDA

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=35.3603603603604, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1788550, Length=406, Percent_Identity=34.4827586206897, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1790299, Length=468, Percent_Identity=32.9059829059829, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789233, Length=315, Percent_Identity=40.6349206349206, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1788905, Length=430, Percent_Identity=32.7906976744186, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.5844155844156, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87082117, Length=281, Percent_Identity=41.9928825622776, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1786524, Length=321, Percent_Identity=40.4984423676012, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=39.1304347826087, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=35.3697749196142, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=34.5161290322581, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=32.7659574468085, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081858, Length=238, Percent_Identity=33.6134453781513, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47352; Mature: 47352

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDG
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
SGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREA
CCCHHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHH
QQGNLGIVGKSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRSGRFVP
CCCCEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE
VNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLR
EECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHHH
AIESRSFMRVGGNEEIVLDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRG
HHHCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
DARLLGLRVIDELNVKYGKRKLPTKSLLRYLACHVWPGNVRELRSFIHYLYLRSDGDLLS
CCEEEHHHHHHHHCHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
APDVEQAVPQADEDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNR
CCCHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LSDKDA
HCCCCC
>Mature Secondary Structure
MDRLSCAIIDDDVEFCDQVVELATDSGFRAKGIHTLGEASRWLDSNFPDLLVVDVGLPDG
CCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
SGFDLIERLDPDHTPQIVVVSGDYARETQGRAQQFGVSEFLTKPFAPERLERVLGGLREA
CCCHHHHHCCCCCCCEEEEEECCCHHHHCCHHHHCCHHHHHHCCCCHHHHHHHHHHHHHH
QQGNLGIVGKSDSIVMLRKDIVRVAPTDLNVLVTGETGTGKDLVARAIHRVSGRSGRFVP
CCCCEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE
VNCGAIPEELLASQLFGHERGSFTGADRRHAGFLEQAAGGTLFLDEIGEMPKRLQVYLLR
EECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHHH
AIESRSFMRVGGNEEIVLDARVVAATHQHVQREQAVLREDLFYRLNEYPIQVPPLRERRG
HHHCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
DARLLGLRVIDELNVKYGKRKLPTKSLLRYLACHVWPGNVRELRSFIHYLYLRSDGDLLS
CCEEEHHHHHHHHCHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
APDVEQAVPQADEDGLLIPAGWTMRQAEDAMIESALARTRFNKKAAARELGISVRTLHNR
CCCHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LSDKDA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]