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The map label for this gene is dtd [H]

Identifier: 84622215

GI number: 84622215

Start: 610388

End: 610828

Strand: Direct

Name: dtd [H]

Synonym: XOO_0558

Alternate gene names: 84622215

Gene position: 610388-610828 (Clockwise)

Preceding gene: 84622213

Following gene: 84622216

Centisome position: 12.36

GC content: 66.21

Gene sequence:

>441_bases
ATGCTTGCACTGATCCAGCGCGTCACCCGCGCCAGCGTCACGGTCGATGACCGGATCGTCGGGCAGATCGGCCCCGGGCT
GCTGGCGCTGATCGGCGTGGAGCCCGGCGACCGCGACGCGCAAACCCGGCGCCTGGCCGAGCGCCTGCTCAGCTACCGCG
TCTTCAGCGACGACGCCGGCAAGATGAATCGCTCACTCACCGACACCAACGGCGGCCTGCTGCTGGTGAGCCAGTTCACC
CTGGCCGCGGACACCAGCTCTGGCAACCGCCCAGGCTTCAGCACCGCGGCACCGCCCGAAGAGGCTGAACGGGCGTTCAA
TCAATTGGTGGACATTTGTCGCGAAAAACATCGCGGCGGGGTGGAAACGGGGCGCTTCGGTGCCCATATGGTTGTCGACC
TGGTCAACGATGGCCCGGTGACCTTTCTTCTCAGACCCTAG

Upstream 100 bases:

>100_bases
TCGCGCAATTCTAAACAGCGCGGCCGGCGAAGACCCGCGCGTGACAGTGCCGGCAGCGCTGGGCATGCTGCGCGGAACAG
TTTGCTGCCAGAGAATGCCC

Downstream 100 bases:

>100_bases
AGACACTACGTCCACCAGCGGTCCCGTCTTGAATCCGGCAGACCGGGCTTCACGCTGGTATAATGATAGGTTCTCTTTCC
AATCTCAAAGCCGGTGGCGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MLALIQRVTRASVTVDDRIVGQIGPGLLALIGVEPGDRDAQTRRLAERLLSYRVFSDDAGKMNRSLTDTNGGLLLVSQFT
LAADTSSGNRPGFSTAAPPEEAERAFNQLVDICREKHRGGVETGRFGAHMVVDLVNDGPVTFLLRP

Sequences:

>Translated_146_residues
MLALIQRVTRASVTVDDRIVGQIGPGLLALIGVEPGDRDAQTRRLAERLLSYRVFSDDAGKMNRSLTDTNGGLLLVSQFT
LAADTSSGNRPGFSTAAPPEEAERAFNQLVDICREKHRGGVETGRFGAHMVVDLVNDGPVTFLLRP
>Mature_146_residues
MLALIQRVTRASVTVDDRIVGQIGPGLLALIGVEPGDRDAQTRRLAERLLSYRVFSDDAGKMNRSLTDTNGGLLLVSQFT
LAADTSSGNRPGFSTAAPPEEAERAFNQLVDICREKHRGGVETGRFGAHMVVDLVNDGPVTFLLRP

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=146, Percent_Identity=40.4109589041096, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=55.1724137931034, Blast_Score=160, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=38.4615384615385, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=34.2465753424658, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281361569, Length=145, Percent_Identity=40.6896551724138, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15761; Mature: 15761

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALIQRVTRASVTVDDRIVGQIGPGLLALIGVEPGDRDAQTRRLAERLLSYRVFSDDAG
CHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
KMNRSLTDTNGGLLLVSQFTLAADTSSGNRPGFSTAAPPEEAERAFNQLVDICREKHRGG
HHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VETGRFGAHMVVDLVNDGPVTFLLRP
CCCCCCCCEEEEEEECCCCEEEEECC
>Mature Secondary Structure
MLALIQRVTRASVTVDDRIVGQIGPGLLALIGVEPGDRDAQTRRLAERLLSYRVFSDDAG
CHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCH
KMNRSLTDTNGGLLLVSQFTLAADTSSGNRPGFSTAAPPEEAERAFNQLVDICREKHRGG
HHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VETGRFGAHMVVDLVNDGPVTFLLRP
CCCCCCCCEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]