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The map label for this gene is trpS

Identifier: 84489462

GI number: 84489462

Start: 762546

End: 763643

Strand: Direct

Name: trpS

Synonym: Msp_0653

Alternate gene names: 84489462

Gene position: 762546-763643 (Clockwise)

Preceding gene: 84489461

Following gene: 84489463

Centisome position: 43.14

GC content: 30.05

Gene sequence:

>1098_bases
TTGAATATGATAGATCCATGGGGTTCTTCAATAATAGACTATGATAAACTTACAGAACAGTTTGGTATTAAACCATTTAC
AGATGTGGTAGATGATATACCACATGCTAGTAAATTAATGACACGTGGTATAATCTTTGGACAAAGGGATTATAATAAAA
TAACTGATGCTCTAAATAACAACAAACCATTTGCTACTATGACTGGAATGATGCCAAGTGGTAAAATGCACATTGGTCAT
AAAATGGTAGTAGATCAATTAAAATGGTACCAGGAAAAAAATGCTGATATTTATGTATCAATAGCAGATATGGAAGCATA
TGCAGCAAGAGGTATAAGTAAGGAAAAATCAAGGGAATTAGCATTAAATGAATATATTACAAACTATATAGCTCTAGGAT
TAGATGTTACTCGTGATAACTTCCATCTTTATCTTCAATCAGAAAATGATGATGTTAAAAATCTAGCATATATAATAGGT
AAAAAAGTTACATTTAATCAGATGAGAAGTATTTATGGATTTAATAATTCAACAAATATTGCTCATATATACACACCACT
ACTACAAGTAGCAGATATTCTTCATCCACAACTTAAAAAATATGGAGGTCCAAAACCTGTAATTGTACCTGTAGGACCAG
ATCAGGATCCACATATTAGATTAACAAGAGATCTTGCAAGTAAATTTAATGAAGAATATGGATTTATAGAGCCATCAGCA
ACGTTCCACAGATTCATGACAGGACTTACTGGAGAAAAAATGAGTAGTAGTAAACCAAAAAGTGCAATATATTTAACTGA
TTCATTAAAAGATGCTGTGAAAAAAGTTAAAAGTGCAAAGACTGGTGGTCGTGAAAGTTTAAAAGAACAAAAAGAACTTG
GTGGTATGCCAGATAAATGTTCAATATATGAATTATTAGTTTATCATTTAATTGATGATGATAAAAAATTAGAAGAAATA
AGAAGTAAATGTTTATCTGGAGAGATACTATGTGGTAATTGTAAAGGATGTGCAAGTGAATTAATAACAGACATGTTTGA
AGAACTTGATCAAAAACGTGAAGAAGCAAGAAAAATTGCAAATACTTTACTAAAATAA

Upstream 100 bases:

>100_bases
TTGCAGTTGTTGATGATGAATATGATATAACATACTATGATATAGAATGGACAAAACCATGAAAAAATAATATATTAAAA
TGAATAGGGAGTGTAATAAA

Downstream 100 bases:

>100_bases
GTAAAATTCTGTTTTTTACTTATAAACTCTTTTTTTTAAACTATTTTTTTAGTGATTTTTTTTCTACTTTAGATTATTTT
TATTCAAAAAATAGATAATA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNMIDPWGSSIIDYDKLTEQFGIKPFTDVVDDIPHASKLMTRGIIFGQRDYNKITDALNNNKPFATMTGMMPSGKMHIGH
KMVVDQLKWYQEKNADIYVSIADMEAYAARGISKEKSRELALNEYITNYIALGLDVTRDNFHLYLQSENDDVKNLAYIIG
KKVTFNQMRSIYGFNNSTNIAHIYTPLLQVADILHPQLKKYGGPKPVIVPVGPDQDPHIRLTRDLASKFNEEYGFIEPSA
TFHRFMTGLTGEKMSSSKPKSAIYLTDSLKDAVKKVKSAKTGGRESLKEQKELGGMPDKCSIYELLVYHLIDDDKKLEEI
RSKCLSGEILCGNCKGCASELITDMFEELDQKREEARKIANTLLK

Sequences:

>Translated_365_residues
MNMIDPWGSSIIDYDKLTEQFGIKPFTDVVDDIPHASKLMTRGIIFGQRDYNKITDALNNNKPFATMTGMMPSGKMHIGH
KMVVDQLKWYQEKNADIYVSIADMEAYAARGISKEKSRELALNEYITNYIALGLDVTRDNFHLYLQSENDDVKNLAYIIG
KKVTFNQMRSIYGFNNSTNIAHIYTPLLQVADILHPQLKKYGGPKPVIVPVGPDQDPHIRLTRDLASKFNEEYGFIEPSA
TFHRFMTGLTGEKMSSSKPKSAIYLTDSLKDAVKKVKSAKTGGRESLKEQKELGGMPDKCSIYELLVYHLIDDDKKLEEI
RSKCLSGEILCGNCKGCASELITDMFEELDQKREEARKIANTLLK
>Mature_365_residues
MNMIDPWGSSIIDYDKLTEQFGIKPFTDVVDDIPHASKLMTRGIIFGQRDYNKITDALNNNKPFATMTGMMPSGKMHIGH
KMVVDQLKWYQEKNADIYVSIADMEAYAARGISKEKSRELALNEYITNYIALGLDVTRDNFHLYLQSENDDVKNLAYIIG
KKVTFNQMRSIYGFNNSTNIAHIYTPLLQVADILHPQLKKYGGPKPVIVPVGPDQDPHIRLTRDLASKFNEEYGFIEPSA
TFHRFMTGLTGEKMSSSKPKSAIYLTDSLKDAVKKVKSAKTGGRESLKEQKELGGMPDKCSIYELLVYHLIDDDKKLEEI
RSKCLSGEILCGNCKGCASELITDMFEELDQKREEARKIANTLLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI47419920, Length=377, Percent_Identity=32.8912466843501, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI47419918, Length=377, Percent_Identity=32.8912466843501, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI47419916, Length=376, Percent_Identity=32.9787234042553, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI47419914, Length=376, Percent_Identity=32.9787234042553, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1789786, Length=316, Percent_Identity=26.8987341772152, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72001474, Length=376, Percent_Identity=30.3191489361702, Blast_Score=161, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6324475, Length=361, Percent_Identity=30.1939058171745, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17864462, Length=380, Percent_Identity=32.3684210526316, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24645295, Length=380, Percent_Identity=32.3684210526316, Blast_Score=163, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- InterPro:   IPR020653 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 41285; Mature: 41285

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMIDPWGSSIIDYDKLTEQFGIKPFTDVVDDIPHASKLMTRGIIFGQRDYNKITDALNN
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
NKPFATMTGMMPSGKMHIGHKMVVDQLKWYQEKNADIYVSIADMEAYAARGISKEKSREL
CCCCEEEECCCCCCCEECHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCHHHHHHH
ALNEYITNYIALGLDVTRDNFHLYLQSENDDVKNLAYIIGKKVTFNQMRSIYGFNNSTNI
HHHHHHHHHHHHCEEEECCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCH
AHIYTPLLQVADILHPQLKKYGGPKPVIVPVGPDQDPHIRLTRDLASKFNEEYGFIEPSA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCH
TFHRFMTGLTGEKMSSSKPKSAIYLTDSLKDAVKKVKSAKTGGRESLKEQKELGGMPDKC
HHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
SIYELLVYHLIDDDKKLEEIRSKCLSGEILCGNCKGCASELITDMFEELDQKREEARKIA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTLLK
HHHCC
>Mature Secondary Structure
MNMIDPWGSSIIDYDKLTEQFGIKPFTDVVDDIPHASKLMTRGIIFGQRDYNKITDALNN
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
NKPFATMTGMMPSGKMHIGHKMVVDQLKWYQEKNADIYVSIADMEAYAARGISKEKSREL
CCCCEEEECCCCCCCEECHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCHHHHHHH
ALNEYITNYIALGLDVTRDNFHLYLQSENDDVKNLAYIIGKKVTFNQMRSIYGFNNSTNI
HHHHHHHHHHHHCEEEECCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCH
AHIYTPLLQVADILHPQLKKYGGPKPVIVPVGPDQDPHIRLTRDLASKFNEEYGFIEPSA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCCCH
TFHRFMTGLTGEKMSSSKPKSAIYLTDSLKDAVKKVKSAKTGGRESLKEQKELGGMPDKC
HHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCH
SIYELLVYHLIDDDKKLEEIRSKCLSGEILCGNCKGCASELITDMFEELDQKREEARKIA
HHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTLLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]