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The map label for this gene is aroC

Identifier: 84489388

GI number: 84489388

Start: 670740

End: 671837

Strand: Direct

Name: aroC

Synonym: Msp_0579

Alternate gene names: 84489388

Gene position: 670740-671837 (Clockwise)

Preceding gene: 84489387

Following gene: 84489391

Centisome position: 37.95

GC content: 31.69

Gene sequence:

>1098_bases
ATGGTTGCAAATACAACAGGAGAAATATTTAAAGTAACAACATTTGGATTAAGTCATGGAAAAGCTTTAGGTGCAACAAT
TGATGGTTGTCCTGCAGGACTTAATCTATCAAATGAAGATATTCAAAATGAATTAAATAAAAGAAGACCTGGAACTAGTA
ACTTAACAACATCAAGAGATGAAAAAGATAAAGTAGAAATATTATCAGGTATATTCAATGGTATGACAGATGGAACACCA
ATAACAGCAATAATATTTAACAAAGACCAAAGAAGTAAAAACTATGATAACTTAAAAAATAATCCAAGACCAGGACATGG
CGATTTTTGTTGGAGAGAAAAATTTGGAAATTATGACTATCGTGGTGGAGGAAGAGGAAGTGGAAGAGTAACAATTGGAC
ATGTAATAGGAGGAGCAGTAAGTAAAAAACTCCTACAACAACATAACATAACAACAACAGCCCATGTAACATCGATTCAT
AACATACATTCAACAAAGAAATTCACATTAAATACTATAAAAGAAAATATTACAAAGAATAATGTTAGATGTGCAGATTT
AGAAGTTGCTACTTTAATGGAAGATGAAATTCTAAAACTTAAAGAAAGGGGAGATAGTACTGGAGGAAAAGTAGAAATAA
TCATTGATAATGTACCTGTAGGTTTAGGTCAACCAGTATTTGATAAGATAGATGGGGACTTTGCAAAGGCATTGATGAAT
ATTGGAGCAGTAAAGGCTGTTGAAGTAGGATGTGGTATTGAAAGTTCAACATTAACAGGACATGAAATGAATGATGAATA
CTACATAGAAGATAATAAAATTCAGACAAAAACAAACAATGCTGGAGGAATTGTTGGTGGTATGACAAATGGTATGCCAA
TTATTTTAAAGATTTCTGTTAAACCAACACCATCAGTAAGTGGAATACAAAATACTGTTAATTTAGAAAAAAGAGAAAAT
TCCACTATAGAAATAGAAGGTCGACATGATCCATGTATCTGTCCAAGAATAACAACAGTTGCAGAAGCAGTATGTAACAT
GGTACTTGCAGATCACATGATAAGAGCAGGATATATTCATCCTGATAAAATAAATTAA

Upstream 100 bases:

>100_bases
ACATTTCTAGAAAAACATATACCTAATGTTAATGAGTCAATTAAACAATCAGTAACATATTTAGATGAAAATAGAATAGA
TTAAAATGGGAGAATAAACA

Downstream 100 bases:

>100_bases
AATATTTTAAAAATAGATCTATTTTAGAAAAATAAAAGTTGTGGTATTTACTTATTATATAACTTTAAAAACTTCTCATG
AGCCAAGTATTCTATGGTAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MVANTTGEIFKVTTFGLSHGKALGATIDGCPAGLNLSNEDIQNELNKRRPGTSNLTTSRDEKDKVEILSGIFNGMTDGTP
ITAIIFNKDQRSKNYDNLKNNPRPGHGDFCWREKFGNYDYRGGGRGSGRVTIGHVIGGAVSKKLLQQHNITTTAHVTSIH
NIHSTKKFTLNTIKENITKNNVRCADLEVATLMEDEILKLKERGDSTGGKVEIIIDNVPVGLGQPVFDKIDGDFAKALMN
IGAVKAVEVGCGIESSTLTGHEMNDEYYIEDNKIQTKTNNAGGIVGGMTNGMPIILKISVKPTPSVSGIQNTVNLEKREN
STIEIEGRHDPCICPRITTVAEAVCNMVLADHMIRAGYIHPDKIN

Sequences:

>Translated_365_residues
MVANTTGEIFKVTTFGLSHGKALGATIDGCPAGLNLSNEDIQNELNKRRPGTSNLTTSRDEKDKVEILSGIFNGMTDGTP
ITAIIFNKDQRSKNYDNLKNNPRPGHGDFCWREKFGNYDYRGGGRGSGRVTIGHVIGGAVSKKLLQQHNITTTAHVTSIH
NIHSTKKFTLNTIKENITKNNVRCADLEVATLMEDEILKLKERGDSTGGKVEIIIDNVPVGLGQPVFDKIDGDFAKALMN
IGAVKAVEVGCGIESSTLTGHEMNDEYYIEDNKIQTKTNNAGGIVGGMTNGMPIILKISVKPTPSVSGIQNTVNLEKREN
STIEIEGRHDPCICPRITTVAEAVCNMVLADHMIRAGYIHPDKIN
>Mature_365_residues
MVANTTGEIFKVTTFGLSHGKALGATIDGCPAGLNLSNEDIQNELNKRRPGTSNLTTSRDEKDKVEILSGIFNGMTDGTP
ITAIIFNKDQRSKNYDNLKNNPRPGHGDFCWREKFGNYDYRGGGRGSGRVTIGHVIGGAVSKKLLQQHNITTTAHVTSIH
NIHSTKKFTLNTIKENITKNNVRCADLEVATLMEDEILKLKERGDSTGGKVEIIIDNVPVGLGQPVFDKIDGDFAKALMN
IGAVKAVEVGCGIESSTLTGHEMNDEYYIEDNKIQTKTNNAGGIVGGMTNGMPIILKISVKPTPSVSGIQNTVNLEKREN
STIEIEGRHDPCICPRITTVAEAVCNMVLADHMIRAGYIHPDKIN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=42.8571428571429, Blast_Score=270, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6321290, Length=363, Percent_Identity=41.8732782369146, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_METST (Q2NGS6)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447620.1
- HSSP:   P63611
- ProteinModelPortal:   Q2NGS6
- SMR:   Q2NGS6
- STRING:   Q2NGS6
- GeneID:   3854830
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0579
- NMPDR:   fig|339860.6.peg.559
- eggNOG:   arNOG04618
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q2NGS6
- ProtClustDB:   PRK05382
- BioCyc:   MSTA339860:MSP_0579-MONOMER
- HAMAP:   MF_00300_A
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39628; Mature: 39628

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVANTTGEIFKVTTFGLSHGKALGATIDGCPAGLNLSNEDIQNELNKRRPGTSNLTTSRD
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EKDKVEILSGIFNGMTDGTPITAIIFNKDQRSKNYDNLKNNPRPGHGDFCWREKFGNYDY
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
RGGGRGSGRVTIGHVIGGAVSKKLLQQHNITTTAHVTSIHNIHSTKKFTLNTIKENITKN
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHCC
NVRCADLEVATLMEDEILKLKERGDSTGGKVEIIIDNVPVGLGQPVFDKIDGDFAKALMN
CCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHH
IGAVKAVEVGCGIESSTLTGHEMNDEYYIEDNKIQTKTNNAGGIVGGMTNGMPIILKISV
CCCEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCEECCCCCCCEEEEEEEE
KPTPSVSGIQNTVNLEKRENSTIEIEGRHDPCICPRITTVAEAVCNMVLADHMIRAGYIH
CCCCCCCCCHHHCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PDKIN
CCCCC
>Mature Secondary Structure
MVANTTGEIFKVTTFGLSHGKALGATIDGCPAGLNLSNEDIQNELNKRRPGTSNLTTSRD
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EKDKVEILSGIFNGMTDGTPITAIIFNKDQRSKNYDNLKNNPRPGHGDFCWREKFGNYDY
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
RGGGRGSGRVTIGHVIGGAVSKKLLQQHNITTTAHVTSIHNIHSTKKFTLNTIKENITKN
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHCC
NVRCADLEVATLMEDEILKLKERGDSTGGKVEIIIDNVPVGLGQPVFDKIDGDFAKALMN
CCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHH
IGAVKAVEVGCGIESSTLTGHEMNDEYYIEDNKIQTKTNNAGGIVGGMTNGMPIILKISV
CCCEEEEEECCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCEECCCCCCCEEEEEEEE
KPTPSVSGIQNTVNLEKRENSTIEIEGRHDPCICPRITTVAEAVCNMVLADHMIRAGYIH
CCCCCCCCCHHHCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PDKIN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA