| Definition | Methanosphaera stadtmanae DSM 3091 chromosome, complete genome. |
|---|---|
| Accession | NC_007681 |
| Length | 1,767,403 |
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The map label for this gene is uvrA
Identifier: 84489384
GI number: 84489384
Start: 665190
End: 668057
Strand: Direct
Name: uvrA
Synonym: Msp_0574
Alternate gene names: 84489384
Gene position: 665190-668057 (Clockwise)
Preceding gene: 84489383
Following gene: 84489385
Centisome position: 37.64
GC content: 31.52
Gene sequence:
>2868_bases ATGGAATCCAAGGAAGAAATAAGAAATAGAGCTATAAAAGATAGAAAAATAATTATAAAAGGAGCAAGAGAACATAATCT TCAAAATATTGATGTTACAATACCACGTGATAACTTCGTGGTAATAACAGGACTTAGTGGTTCTGGAAAATCATCACTGG CATTTGATACAATCTATGCTGAAGGACAAAGAAGATATGTTGAATCTCTATCAGCATATGCAAGACAATTTCTAGGACAA ATGGAAAAACCAGAAATAGACTACATTGAAGGTCTATCTCCTGCAATATCAATAGACCAAAAAACCACTAGATCAAATCC CAGATCCACTGTAGGTACTGTTACAGAAATCTATGATTATCTTAGATTATTATATGCAAGAATAGGTGTGGCTCATTGTT ATAACTGTGGAAAGGAAATATCACAACAAACACCAGGACAAATAGCACAAGAAATAATAGAAAACAATGATCAAGAAAAG ATATACATACTAGCACCAGTTGTGAAAAATAGGAAAGGAATGCATAAGAAGATATTTTCCACATATAAACAAAAGGGATA TGTGAGAGTACGTGTTGATGGTGAGATTAAAAGCTTAGATGAAACAATAGAACTTGATAAAAATCAAAAACATGTAATAG AAATAGTAATTGACAGATTAAAAGTAGCAAATAATGAAAATTTCCGTAGAAGATTAGTTGAAGCAGTGGAAAATGCACTT AGAATAAGTGAAGGACTAGTTACAGTAGCAAATAATGATAATTCCATTCCAGATCAATACTATAGTGAAGCATTAGCCTG TCCAGATTGTGGAATAAATTTCCTAGAAATAAGTCCAAGAATGTTTTCATTTAACAATCCCCAAGCTGCATGTCCAACAT GTAATGGTATAGGAAGTACATTTGAAATAGATGAAGATTTAATAGTTCCAAATAAAACCTTATCAATAAGAGAAGGTGCT ATTAAACCTTGGAGTAATTCTACAAGTACAGAAACATACTACAATAGAATACTTGCAGGGGTAGCAACACACTATGGATT TAAAGTAGATGTACCATACCATACTTTATCTAGAAAAAATAAGGATGTAATATTATATGGAAGTAATGGTGAAAATATAA CATTTTCATTTATTAGAAATAATAAGGAAAAACGTGTTACAAAACCATTTGAAGGAGTAATTCCATATATGAAACGAATA TTTCTGGAAACAAAATCAAGATACAGAAGAAAAGCAATACATTCATATATGACATTAAATAAGTGTCCAACATGTCATGG AGATAGGCTTAAACCAGAAATGTTAGCAGTTACTGTTGGAGATATGAATATAGCTGATGTTACAAAATTATCTTTATCTA AGGCAAAGGAGTTCTTTGAAAATCTTAAATTAACTAAACGTCAGGAATTTATTGGACATGAAATACTAAAAGAAATAAGA GAAAGATTATCATTTCTAAATGATGTAGGACTTAACTATTTAACACTTGCCAGGTCATCTGGTACATTATCTGGTGGAGA AGCTCAACGTATAAGACTAGCAACACAAATTGGAAGTAGATTAGTTGGAGTTTTATATGTTTTAGATGAACCAAGCATAG GATTACATCAAAGAGATAATATGAAACTTATTGAAACATTAAAACATCTTAGGGATCTTGGAAATACTTTGATTGTAGTA GAACATGATGAGGAAACAATACTTGAAGCAGATCATGTTATTGACATAGGACCTGGGGCAGGGGATCATGGAGGAATTGT AACAGCACAGGGAACACCTGATGAAATTAAAAATAATGAGAATTCATTAACAGGACAGTACTTATCTGGAACTAAGAAAA TACCAGTACCAAAAACTCGTCATGAAGGAAATGGAAAATCAATAAAAATAATAGGAGCAAGTGAAAATAATCTTAAAAAC ATAGATGTGGAATTTCCATTGGGTAAATTTATATGTGTAACAGGAGTATCAGGTTCTGGAAAAAGTACACTTGTAAATAA AATATTGTATCTTGGATTATATGAACTTCTTACAAATAAACATAAAGATAAAGTAGGATGTCATAAAAAGATTATAGGTT CTGAAAATATTGATAAAATCATTGTAATTGACCAGTCACCTATTGGAAGAACACCTCGTTCAAATCCTGCAACATATATT GGATTATTCACATATATTCGTGAATTATTTGCACAAACACCAGAAGCAAAACAGAATGGATATAAACCTGGAAGATTTAG TTTCAATGTTAAAGGAGGAAGATGTGAAGCATGTTCTGGTGATGGAATTGTACAGATAGAGATGCATTTTCTAGCAGATG TATATGTTCCATGTGAAGTATGTGGTGGTAAACGTTACAATCAAGAAACATTGAATATTAGATATAAAGGTAAAAATATC AATGATGTACTGGAAATGACAAGTAGTGAAGCATTAGAGTTTTTCAAACACATACCTAAGATAAAAAGAAAATTACAAAC CCTGGTTGATGTTGGACTTGGATATGTTAAACTTGGTCAGCCAGCAACAACATTATCTGGTGGAGAAGCTCAGCGTATAA AATTAGCTAAGGAATTAAGTAGACAAAATACACACAATACATTATATATTCTAGATGAACCAACAACAGGTCTTCACTTT GATGATATTAACAGATTATTAAAGGTATTATTAAAACTTAGGAATCAGGGAAATACATTGGTTGTTATTGAACATAATCT TGATGTTGTAAAAACTGCAGATTATATAATTGATTTAGGTCCTGAAGGAGGTAATGGTGGAGGTTGGCTAATAGCTGAGG GAACTCCTGAAGAGATAGCTAAACAAGATACTTATACAGGTATTTATCTTAAGCCAATGCTTGAATAA
Upstream 100 bases:
>100_bases AGAACTTGAAAAAGAAATGAAACAAGCTGCAAAAGATCTTAACTTTGAAAAGGCTGCAAAACTAAGAGATAGGATAATGG AATTAAAAGAGGAATAAATA
Downstream 100 bases:
>100_bases ACCTCATACATATATTTGAATTAAGTTTGTTCAATTATACTTTAATTTAGAGTTTAATAAAAAATAATATCATATTTATA AGAAATATAGATAAGTTTAT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 955; Mature: 955
Protein sequence:
>955_residues MESKEEIRNRAIKDRKIIIKGAREHNLQNIDVTIPRDNFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQ MEKPEIDYIEGLSPAISIDQKTTRSNPRSTVGTVTEIYDYLRLLYARIGVAHCYNCGKEISQQTPGQIAQEIIENNDQEK IYILAPVVKNRKGMHKKIFSTYKQKGYVRVRVDGEIKSLDETIELDKNQKHVIEIVIDRLKVANNENFRRRLVEAVENAL RISEGLVTVANNDNSIPDQYYSEALACPDCGINFLEISPRMFSFNNPQAACPTCNGIGSTFEIDEDLIVPNKTLSIREGA IKPWSNSTSTETYYNRILAGVATHYGFKVDVPYHTLSRKNKDVILYGSNGENITFSFIRNNKEKRVTKPFEGVIPYMKRI FLETKSRYRRKAIHSYMTLNKCPTCHGDRLKPEMLAVTVGDMNIADVTKLSLSKAKEFFENLKLTKRQEFIGHEILKEIR ERLSFLNDVGLNYLTLARSSGTLSGGEAQRIRLATQIGSRLVGVLYVLDEPSIGLHQRDNMKLIETLKHLRDLGNTLIVV EHDEETILEADHVIDIGPGAGDHGGIVTAQGTPDEIKNNENSLTGQYLSGTKKIPVPKTRHEGNGKSIKIIGASENNLKN IDVEFPLGKFICVTGVSGSGKSTLVNKILYLGLYELLTNKHKDKVGCHKKIIGSENIDKIIVIDQSPIGRTPRSNPATYI GLFTYIRELFAQTPEAKQNGYKPGRFSFNVKGGRCEACSGDGIVQIEMHFLADVYVPCEVCGGKRYNQETLNIRYKGKNI NDVLEMTSSEALEFFKHIPKIKRKLQTLVDVGLGYVKLGQPATTLSGGEAQRIKLAKELSRQNTHNTLYILDEPTTGLHF DDINRLLKVLLKLRNQGNTLVVIEHNLDVVKTADYIIDLGPEGGNGGGWLIAEGTPEEIAKQDTYTGIYLKPMLE
Sequences:
>Translated_955_residues MESKEEIRNRAIKDRKIIIKGAREHNLQNIDVTIPRDNFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQ MEKPEIDYIEGLSPAISIDQKTTRSNPRSTVGTVTEIYDYLRLLYARIGVAHCYNCGKEISQQTPGQIAQEIIENNDQEK IYILAPVVKNRKGMHKKIFSTYKQKGYVRVRVDGEIKSLDETIELDKNQKHVIEIVIDRLKVANNENFRRRLVEAVENAL RISEGLVTVANNDNSIPDQYYSEALACPDCGINFLEISPRMFSFNNPQAACPTCNGIGSTFEIDEDLIVPNKTLSIREGA IKPWSNSTSTETYYNRILAGVATHYGFKVDVPYHTLSRKNKDVILYGSNGENITFSFIRNNKEKRVTKPFEGVIPYMKRI FLETKSRYRRKAIHSYMTLNKCPTCHGDRLKPEMLAVTVGDMNIADVTKLSLSKAKEFFENLKLTKRQEFIGHEILKEIR ERLSFLNDVGLNYLTLARSSGTLSGGEAQRIRLATQIGSRLVGVLYVLDEPSIGLHQRDNMKLIETLKHLRDLGNTLIVV EHDEETILEADHVIDIGPGAGDHGGIVTAQGTPDEIKNNENSLTGQYLSGTKKIPVPKTRHEGNGKSIKIIGASENNLKN IDVEFPLGKFICVTGVSGSGKSTLVNKILYLGLYELLTNKHKDKVGCHKKIIGSENIDKIIVIDQSPIGRTPRSNPATYI GLFTYIRELFAQTPEAKQNGYKPGRFSFNVKGGRCEACSGDGIVQIEMHFLADVYVPCEVCGGKRYNQETLNIRYKGKNI NDVLEMTSSEALEFFKHIPKIKRKLQTLVDVGLGYVKLGQPATTLSGGEAQRIKLAKELSRQNTHNTLYILDEPTTGLHF DDINRLLKVLLKLRNQGNTLVVIEHNLDVVKTADYIIDLGPEGGNGGGWLIAEGTPEEIAKQDTYTGIYLKPMLE >Mature_955_residues MESKEEIRNRAIKDRKIIIKGAREHNLQNIDVTIPRDNFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQ MEKPEIDYIEGLSPAISIDQKTTRSNPRSTVGTVTEIYDYLRLLYARIGVAHCYNCGKEISQQTPGQIAQEIIENNDQEK IYILAPVVKNRKGMHKKIFSTYKQKGYVRVRVDGEIKSLDETIELDKNQKHVIEIVIDRLKVANNENFRRRLVEAVENAL RISEGLVTVANNDNSIPDQYYSEALACPDCGINFLEISPRMFSFNNPQAACPTCNGIGSTFEIDEDLIVPNKTLSIREGA IKPWSNSTSTETYYNRILAGVATHYGFKVDVPYHTLSRKNKDVILYGSNGENITFSFIRNNKEKRVTKPFEGVIPYMKRI FLETKSRYRRKAIHSYMTLNKCPTCHGDRLKPEMLAVTVGDMNIADVTKLSLSKAKEFFENLKLTKRQEFIGHEILKEIR ERLSFLNDVGLNYLTLARSSGTLSGGEAQRIRLATQIGSRLVGVLYVLDEPSIGLHQRDNMKLIETLKHLRDLGNTLIVV EHDEETILEADHVIDIGPGAGDHGGIVTAQGTPDEIKNNENSLTGQYLSGTKKIPVPKTRHEGNGKSIKIIGASENNLKN IDVEFPLGKFICVTGVSGSGKSTLVNKILYLGLYELLTNKHKDKVGCHKKIIGSENIDKIIVIDQSPIGRTPRSNPATYI GLFTYIRELFAQTPEAKQNGYKPGRFSFNVKGGRCEACSGDGIVQIEMHFLADVYVPCEVCGGKRYNQETLNIRYKGKNI NDVLEMTSSEALEFFKHIPKIKRKLQTLVDVGLGYVKLGQPATTLSGGEAQRIKLAKELSRQNTHNTLYILDEPTTGLHF DDINRLLKVLLKLRNQGNTLVVIEHNLDVVKTADYIIDLGPEGGNGGGWLIAEGTPEEIAKQDTYTGIYLKPMLE
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=943, Percent_Identity=55.6733828207847, Blast_Score=1046, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 106951; Mature: 106951
Theoretical pI: Translated: 8.62; Mature: 8.62
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MESKEEIRNRAIKDRKIIIKGAREHNLQNIDVTIPRDNFVVITGLSGSGKSSLAFDTIYA CCCHHHHHHHHCCCCEEEEECCHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEHHHHH EGQRRYVESLSAYARQFLGQMEKPEIDYIEGLSPAISIDQKTTRSNPRSTVGTVTEIYDY HHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEECCCHHCCCCCCHHHHHHHHHHHH LRLLYARIGVAHCYNCGKEISQQTPGQIAQEIIENNDQEKIYILAPVVKNRKGMHKKIFS HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH TYKQKGYVRVRVDGEIKSLDETIELDKNQKHVIEIVIDRLKVANNENFRRRLVEAVENAL HHHHCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH RISEGLVTVANNDNSIPDQYYSEALACPDCGINFLEISPRMFSFNNPQAACPTCNGIGST HHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCC FEIDEDLIVPNKTLSIREGAIKPWSNSTSTETYYNRILAGVATHYGFKVDVPYHTLSRKN EECCCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHCCCC KDVILYGSNGENITFSFIRNNKEKRVTKPFEGVIPYMKRIFLETKSRYRRKAIHSYMTLN CCEEEECCCCCEEEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC KCPTCHGDRLKPEMLAVTVGDMNIADVTKLSLSKAKEFFENLKLTKRQEFIGHEILKEIR CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH ERLSFLNDVGLNYLTLARSSGTLSGGEAQRIRLATQIGSRLVGVLYVLDEPSIGLHQRDN HHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCC MKLIETLKHLRDLGNTLIVVEHDEETILEADHVIDIGPGAGDHGGIVTAQGTPDEIKNNE HHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCEEECCCCCCCCCCEEEECCCHHHHCCCC NSLTGQYLSGTKKIPVPKTRHEGNGKSIKIIGASENNLKNIDVEFPLGKFICVTGVSGSG CCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCC KSTLVNKILYLGLYELLTNKHKDKVGCHKKIIGSENIDKIIVIDQSPIGRTPRSNPATYI HHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHH GLFTYIRELFAQTPEAKQNGYKPGRFSFNVKGGRCEACSGDGIVQIEMHFLADVYVPCEV HHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCEEECCCCCCEEEEEEEEHHHHEEEHHH CGGKRYNQETLNIRYKGKNINDVLEMTSSEALEFFKHIPKIKRKLQTLVDVGLGYVKLGQ CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC PATTLSGGEAQRIKLAKELSRQNTHNTLYILDEPTTGLHFDDINRLLKVLLKLRNQGNTL CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE VVIEHNLDVVKTADYIIDLGPEGGNGGGWLIAEGTPEEIAKQDTYTGIYLKPMLE EEEECCCCEEEECCEEEEECCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEECCC >Mature Secondary Structure MESKEEIRNRAIKDRKIIIKGAREHNLQNIDVTIPRDNFVVITGLSGSGKSSLAFDTIYA CCCHHHHHHHHCCCCEEEEECCHHCCCCEEEEEECCCCEEEEEECCCCCCCCEEEHHHHH EGQRRYVESLSAYARQFLGQMEKPEIDYIEGLSPAISIDQKTTRSNPRSTVGTVTEIYDY HHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEECCCHHCCCCCCHHHHHHHHHHHH LRLLYARIGVAHCYNCGKEISQQTPGQIAQEIIENNDQEKIYILAPVVKNRKGMHKKIFS HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH TYKQKGYVRVRVDGEIKSLDETIELDKNQKHVIEIVIDRLKVANNENFRRRLVEAVENAL HHHHCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH RISEGLVTVANNDNSIPDQYYSEALACPDCGINFLEISPRMFSFNNPQAACPTCNGIGST HHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCC FEIDEDLIVPNKTLSIREGAIKPWSNSTSTETYYNRILAGVATHYGFKVDVPYHTLSRKN EECCCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHCCCC KDVILYGSNGENITFSFIRNNKEKRVTKPFEGVIPYMKRIFLETKSRYRRKAIHSYMTLN CCEEEECCCCCEEEEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC KCPTCHGDRLKPEMLAVTVGDMNIADVTKLSLSKAKEFFENLKLTKRQEFIGHEILKEIR CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH ERLSFLNDVGLNYLTLARSSGTLSGGEAQRIRLATQIGSRLVGVLYVLDEPSIGLHQRDN HHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCC MKLIETLKHLRDLGNTLIVVEHDEETILEADHVIDIGPGAGDHGGIVTAQGTPDEIKNNE HHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCEEECCCCCCCCCCEEEECCCHHHHCCCC NSLTGQYLSGTKKIPVPKTRHEGNGKSIKIIGASENNLKNIDVEFPLGKFICVTGVSGSG CCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCC KSTLVNKILYLGLYELLTNKHKDKVGCHKKIIGSENIDKIIVIDQSPIGRTPRSNPATYI HHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHH GLFTYIRELFAQTPEAKQNGYKPGRFSFNVKGGRCEACSGDGIVQIEMHFLADVYVPCEV HHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCEEECCCCCCEEEEEEEEHHHHEEEHHH CGGKRYNQETLNIRYKGKNINDVLEMTSSEALEFFKHIPKIKRKLQTLVDVGLGYVKLGQ CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC PATTLSGGEAQRIKLAKELSRQNTHNTLYILDEPTTGLHFDDINRLLKVLLKLRNQGNTL CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE VVIEHNLDVVKTADYIIDLGPEGGNGGGWLIAEGTPEEIAKQDTYTGIYLKPMLE EEEECCCCEEEECCEEEEECCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9371463 [H]