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The map label for this gene is argC

Identifier: 84489362

GI number: 84489362

Start: 644829

End: 645857

Strand: Direct

Name: argC

Synonym: Msp_0552

Alternate gene names: 84489362

Gene position: 644829-645857 (Clockwise)

Preceding gene: 84489361

Following gene: 84489363

Centisome position: 36.48

GC content: 32.56

Gene sequence:

>1029_bases
ATGAGTAAAATAGATGTTGCAATAATAGGTGCAAGTGGATATACTGGGGGAGAATTAGTTAGATTATTAACAAGACATCC
AAGGGTAAATATTTCCACAGTAACAAGTAGAAAAAATAATGGTGAAGACCTATCATCTCTTCATCCAAATCTGCAGGATT
TAGATTTAAAATTCACAAATCCTGATACTAAAGATATAGATGCAGATGTAGTATTTAGTGCACTACCACATGGTGTATCA
ATGAAATTAGTACCAGAATACTTGGATAATGGGGCTCGTGTCATTGATTTAAGTGGAGACTTTAGATTTAGTGATGTTTC
TGTATATGAAAAATGGTATGGAATGAAACATGAACATCCAGATTTAAAAGCAGTATTTGGACTTCCAGAAATTAACAGAG
ATAAAATAAAAGATGCAACTTTAATAGCAAACCCTGGATGTTTCCCAACAGGAGCAATACTATCGAGTCTTCCAATAGTA
GAAAATAAATTAGTAGATAGAATAATATTAGATAGTAAAAGTGGAGTAAGTGGTGCTGGAATATCACCAAATAACAACAC
ACACTATCCTACATGTGCTGATAACATAAAACCATATGCAATAGCAAATCATAGGCACACACCAGAGATACGAGAACAAT
TAAGAAACTTTGGGACAGGCACTGTTAAAGTATCATTTACACCACATCTTGTACCAGTAATTCGTGGAATAATAACAACA
AATCATAGTTTCCTACTTAAAAATGATGTTTCAGCTAGTGATGTTCATGATTTATACATGGATTATTATAAGAATGAACC
ATTTGTAAAAGTATTAAAAGATAACAACATACCTTTACTTGCTAGTGTAAGAGGATCTAATTACTGTCAAATAGGTGGTA
TTTCATTAGATGATGAAGATGAGCTTGTTGTTGTCTCAGCAATAGATAACCTAGTAAAAGGAGCTTCAGGTCAAGCTATT
CAAAACATGAATATCATGTTTGGATTTGATGAAACTGAAGGACTTAAAGAATTAGGATTATATCCATAG

Upstream 100 bases:

>100_bases
CAAAAACATAGAAAAAGATATAATAGATAAAGTTGCAAAAACACACTTTAAAAATATTAAACCATACACATAAAGAAAAT
GGTTTTTAGGAGTATAAAAT

Downstream 100 bases:

>100_bases
GTGAATATATGTCAGATTTAGTAGTGTATTATACAAGAACAAATACAACTAAAAATGTTGCTAGTATCATTAAAGATGAG
TTAGATGCTGATGTATTGGA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSKIDVAIIGASGYTGGELVRLLTRHPRVNISTVTSRKNNGEDLSSLHPNLQDLDLKFTNPDTKDIDADVVFSALPHGVS
MKLVPEYLDNGARVIDLSGDFRFSDVSVYEKWYGMKHEHPDLKAVFGLPEINRDKIKDATLIANPGCFPTGAILSSLPIV
ENKLVDRIILDSKSGVSGAGISPNNNTHYPTCADNIKPYAIANHRHTPEIREQLRNFGTGTVKVSFTPHLVPVIRGIITT
NHSFLLKNDVSASDVHDLYMDYYKNEPFVKVLKDNNIPLLASVRGSNYCQIGGISLDDEDELVVVSAIDNLVKGASGQAI
QNMNIMFGFDETEGLKELGLYP

Sequences:

>Translated_342_residues
MSKIDVAIIGASGYTGGELVRLLTRHPRVNISTVTSRKNNGEDLSSLHPNLQDLDLKFTNPDTKDIDADVVFSALPHGVS
MKLVPEYLDNGARVIDLSGDFRFSDVSVYEKWYGMKHEHPDLKAVFGLPEINRDKIKDATLIANPGCFPTGAILSSLPIV
ENKLVDRIILDSKSGVSGAGISPNNNTHYPTCADNIKPYAIANHRHTPEIREQLRNFGTGTVKVSFTPHLVPVIRGIITT
NHSFLLKNDVSASDVHDLYMDYYKNEPFVKVLKDNNIPLLASVRGSNYCQIGGISLDDEDELVVVSAIDNLVKGASGQAI
QNMNIMFGFDETEGLKELGLYP
>Mature_341_residues
SKIDVAIIGASGYTGGELVRLLTRHPRVNISTVTSRKNNGEDLSSLHPNLQDLDLKFTNPDTKDIDADVVFSALPHGVSM
KLVPEYLDNGARVIDLSGDFRFSDVSVYEKWYGMKHEHPDLKAVFGLPEINRDKIKDATLIANPGCFPTGAILSSLPIVE
NKLVDRIILDSKSGVSGAGISPNNNTHYPTCADNIKPYAIANHRHTPEIREQLRNFGTGTVKVSFTPHLVPVIRGIITTN
HSFLLKNDVSASDVHDLYMDYYKNEPFVKVLKDNNIPLLASVRGSNYCQIGGISLDDEDELVVVSAIDNLVKGASGQAIQ
NMNIMFGFDETEGLKELGLYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=39.8255813953488, Blast_Score=221, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6320913, Length=343, Percent_Identity=33.8192419825073, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_METST (Q2NGV2)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447594.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q2NGV2
- SMR:   Q2NGV2
- STRING:   Q2NGV2
- GeneID:   3854803
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0552
- NMPDR:   fig|339860.6.peg.534
- eggNOG:   arNOG05044
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q2NGV2
- ProtClustDB:   PRK00436
- BioCyc:   MSTA339860:MSP_0552-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37546; Mature: 37415

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDVAIIGASGYTGGELVRLLTRHPRVNISTVTSRKNNGEDLSSLHPNLQDLDLKFTN
CCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCHHHCEEEECC
PDTKDIDADVVFSALPHGVSMKLVPEYLDNGARVIDLSGDFRFSDVSVYEKWYGMKHEHP
CCCCCCCHHHHHHHCCCCCEEEEEHHHHCCCCEEEECCCCCEECHHHHHHHHCCCCCCCC
DLKAVFGLPEINRDKIKDATLIANPGCFPTGAILSSLPIVENKLVDRIILDSKSGVSGAG
CCEEEECCCCCCHHHCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHEECCCCCCCCCC
ISPNNNTHYPTCADNIKPYAIANHRHTPEIREQLRNFGTGTVKVSFTPHLVPVIRGIITT
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHC
NHSFLLKNDVSASDVHDLYMDYYKNEPFVKVLKDNNIPLLASVRGSNYCQIGGISLDDED
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCEEEECCCCCCCCC
ELVVVSAIDNLVKGASGQAIQNMNIMFGFDETEGLKELGLYP
CEEEEEEHHHHHCCCCCCEEECCEEEEECCCCCCHHHHCCCC
>Mature Secondary Structure 
SKIDVAIIGASGYTGGELVRLLTRHPRVNISTVTSRKNNGEDLSSLHPNLQDLDLKFTN
CCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCHHHCEEEECC
PDTKDIDADVVFSALPHGVSMKLVPEYLDNGARVIDLSGDFRFSDVSVYEKWYGMKHEHP
CCCCCCCHHHHHHHCCCCCEEEEEHHHHCCCCEEEECCCCCEECHHHHHHHHCCCCCCCC
DLKAVFGLPEINRDKIKDATLIANPGCFPTGAILSSLPIVENKLVDRIILDSKSGVSGAG
CCEEEECCCCCCHHHCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHEECCCCCCCCCC
ISPNNNTHYPTCADNIKPYAIANHRHTPEIREQLRNFGTGTVKVSFTPHLVPVIRGIITT
CCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHC
NHSFLLKNDVSASDVHDLYMDYYKNEPFVKVLKDNNIPLLASVRGSNYCQIGGISLDDED
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCEEEECCCCCCCCC
ELVVVSAIDNLVKGASGQAIQNMNIMFGFDETEGLKELGLYP
CEEEEEEHHHHHCCCCCCEEECCEEEEECCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA