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The map label for this gene is argB

Identifier: 84489360

GI number: 84489360

Start: 642983

End: 643879

Strand: Direct

Name: argB

Synonym: Msp_0550

Alternate gene names: 84489360

Gene position: 642983-643879 (Clockwise)

Preceding gene: 84489359

Following gene: 84489361

Centisome position: 36.38

GC content: 32.33

Gene sequence:

>897_bases
ATGGTTGATCAAGAACAATTCGATATTAGTAATGTTTTAATTGAAGCATTACCCTACATAAAAAAGTTTCATAATAAAAA
AATCATGATTAAGTATGGTGGTCATGCAATGATTGATGAGAATGCTATGAGTTCCACAGCACGAGATACTGTACTTCTTA
AATATGTTGGTATGCAACCTATTGTTGTTCATGGTGGAGGTCCAGAAATTTCCAGATCCATGGATAAAATGGGTAAAGAA
CCTAAATTTATTGGTGGTTTAAGAGTTACAGATAAAGAAACTATGGAGATTGTTAAAATGGTTTTGGTGGGTAAAATCAA
CACTGAAATTGTTTCTAAACTTGGATTCCATGGTGGAAAGAGTGTTGGTATTTCTGGTAAAGATAGTTATCTTGTTGAAG
CATCAAGAAAAGGACTTACTAAGGTTAAACATGAGAATGGTGAAGTTTTAGAAGTTGATTTAGGTTATGTTGGTAAGATT
GACAGGGTAAATAAACAACTTGTTGATGATTTAACTAACAACAATTATATACCTGTTATTTCACCTTTAGGAATTGATGA
TGATGGAAATACTCTTAATTTGAATGCTGATACTGTTGCAGGTTCTATTGCATCTGAGGTTAATGCTGAAAAGCTTATTG
TACTTACTGATGTTCCTGGTATTTTAACAGATCCTGATGATCCTGAGAGTATGATTAGACGTATTCGTACTGATGAATTG
AAGGAACTTATTAAGGATGGTATTATTACTGGAGGTATGATTCCTAAGGTAGAAACTTGTATTAATGCTGTTGAAAATGG
TGTTAAAACTGCTCATATTCTTGATGGTAGACTTAATCATTCTATTTTATTAGAAATCTTCACAAAACATGGAATAGGTA
CAATGGTACGTGAATAA

Upstream 100 bases:

>100_bases
GGATGTTATAGTGCAACTGCATATGGTTGTGATTTAACATATGATTATGTAAAGATTAATGCTGAATACACCACATAAAT
AGTTAAATGGAGTTTAAATA

Downstream 100 bases:

>100_bases
TAATGTATCTCTTTTTTTAATTATTTTTTCAAGTGTTTATATGAAATCAGTTAAATTATCAAATAGTGAAATTAAATCTT
TTATGGAAAAAACCAGTACA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQPIVVHGGGPEISRSMDKMGKE
PKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGKSVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKI
DRVNKQLVDDLTNNNYIPVISPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDEL
KELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE

Sequences:

>Translated_298_residues
MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQPIVVHGGGPEISRSMDKMGKE
PKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGKSVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKI
DRVNKQLVDDLTNNNYIPVISPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDEL
KELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE
>Mature_298_residues
MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQPIVVHGGGPEISRSMDKMGKE
PKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGKSVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKI
DRVNKQLVDDLTNNNYIPVISPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDEL
KELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=302, Percent_Identity=24.8344370860927, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI145693208, Length=239, Percent_Identity=30.9623430962343, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=286, Percent_Identity=26.5734265734266, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_METST (Q2NGV4)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447592.1
- HSSP:   Q9X2A4
- ProteinModelPortal:   Q2NGV4
- SMR:   Q2NGV4
- STRING:   Q2NGV4
- GeneID:   3854801
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0550
- NMPDR:   fig|339860.6.peg.532
- eggNOG:   arNOG04941
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q2NGV4
- ProtClustDB:   PRK00942
- BioCyc:   MSTA339860:MSP_0550-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_A
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32586; Mature: 32586

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: BINDING 88-88 BINDING 193-193

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQP
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCHHHHHHHHHEEEEEEECCCE
IVVHGGGPEISRSMDKMGKEPKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGK
EEEECCCCHHHHHHHHHCCCCCEECCEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
SVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKIDRVNKQLVDDLTNNNYIPVI
EECCCCCCCEEEEHHHCCCHHEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
SPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDEL
ECCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCHHHH
KELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQP
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCHHHHHHHHHEEEEEEECCCE
IVVHGGGPEISRSMDKMGKEPKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGK
EEEECCCCHHHHHHHHHCCCCCEECCEEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
SVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKIDRVNKQLVDDLTNNNYIPVI
EECCCCCCCEEEEHHHCCCHHEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEE
SPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDEL
ECCCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCHHHH
KELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA