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The map label for this gene is yhcC [C]

Identifier: 84489186

GI number: 84489186

Start: 438763

End: 440388

Strand: Direct

Name: yhcC [C]

Synonym: Msp_0372

Alternate gene names: 84489186

Gene position: 438763-440388 (Clockwise)

Preceding gene: 84489184

Following gene: 84489187

Centisome position: 24.83

GC content: 30.5

Gene sequence:

>1626_bases
ATGCAGGAAGCGTGTAGATTAATAATAGAAGAAGCATTAAGTAGAAATATAACTACAAAGAAGGATTTAGAAAAACTTAA
AATTCAAACATGTAGAGACTTAAAATTAAGTGGCTTCATGAGTAATTCTAAAATTTTACAGTATGCAAAACCAGAAGAAT
TAGAAAGTTTAAGACCAATTCTAATGAAAAAACCAACACGTACAATTTCTGGTGTTGCAATAGTAGCAGTTATGTGTAGG
CCACATAAATGTCCACATGGACGATGTAAATACTGTCCTGAGAGTAGCATTGCTCCTCCAAGTTATACTGGTGAGGAACC
TGCAGCTTTACGAGCAAGAATGTTCCATTTTCATCCATATGTTCAAACATTCAACAGATTATATCAACTAAAAAATATTG
GTCATTCCATAGATAAGGTGGAATTAATAATAATGGGCGGAACCTTTGCTTCATGTACTCTTGATTATCAGGAATGGTTT
GTAACACAATGTTTAAGGGCAATGAATGATTTTGAAACAGTTAGTAAGAAAATACCAGTAAATCAAAGGGAAATCAAAAT
AATACCTCCAGAGGATTTCCAATACATACATGATGCACAGAAAAATAATGAACATTCAAAGGTAAGATGTATAGGATTAA
CATTTGAAACAAGACCAGATTATGCTAAAATGGAAGATATTAATAGAATGTTACAATTTGGAGTAACACGTGTTGAATTA
GGTGTTCAAACATTATATAATCATATATATAAACGAGTTGATAGAGGTCATAAAATTCAAGATGTAATAGAGGCAAATCA
ATTATTACGAGATTCTGGAATAAAAGTTGCCATGCATATGATGCCAGGACTTTTATCTTCATTTAGTAGTGATGTTAACA
TGTTTAAACGTTTATTTAATGAACCATTATTTTCACCAGACATGTTAAAAATCTATCCATGTCTTGTTACAGAGGGCTCA
GAATTCTATGATATGTGGAAAAAGGGCGAATATGAACCATACACATCTCAACAAGCAGTGGATTTAATAGTTGAAGTTAA
AAAAATTCTACCAAAATGGGTTAGAACAATGAGAATTCAAAGAGATATTCCAGCAACATTAATTGATGCTGGAGTTAAAA
AATCAAATCTTGGAGAATTAGTATATAATCGTCTTGAAGAGGAGGATATTCAATGTCAATGTATTAGATGTAGAGAGGTA
GGTCATAAAAAGGCACATGGAATAGAACCTGACTATAATAATATAGAATTACTAAGAACAGATTATGATGTAGTAGGTGG
ACATGAAATATTTTTATCTATAGAAGATGTGGAAAATGATATTTTAATTGGATTTACTCGTTTAAGAATACCATCCAATA
GAGTATTTAGGAAGGAAATTACAAGTTCAAGTTCATTGATTAGAGAATTACATGTTTATGGACAAATGCAGAAAATTGGT
AAAAATGATGATAATTTATGGCAACATAAAGGTTATGGTGCCCAATTATTAGAAGAAGCTGAAAAAATAGCAAAAGATGA
ATATAATAAAAATAAAATGCTAATAATTAGTGGAATTGGTGTAAGAGATTATTATCGTAAATTTGGATATTATAAGGATG
GTCCATACATGTCTAAATTCATTTAA

Upstream 100 bases:

>100_bases
TATAATAATATTGATTTTCTTATTAAAATAATCTTTTGTTTTATTAATTTTTAAATAAATAATTTAATTGTATGACTAAT
AAAAAGGAGGAGAATAAAAG

Downstream 100 bases:

>100_bases
TTATTCCTTTTCTTTTTATTATTCTCTTTTTATTAAATTACTTATTTATCTATTCTTGAAAAAATAATAAATAGTATAAA
TAATAATTCATAAAGATAAA

Product: histone acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MQEACRLIIEEALSRNITTKKDLEKLKIQTCRDLKLSGFMSNSKILQYAKPEELESLRPILMKKPTRTISGVAIVAVMCR
PHKCPHGRCKYCPESSIAPPSYTGEEPAALRARMFHFHPYVQTFNRLYQLKNIGHSIDKVELIIMGGTFASCTLDYQEWF
VTQCLRAMNDFETVSKKIPVNQREIKIIPPEDFQYIHDAQKNNEHSKVRCIGLTFETRPDYAKMEDINRMLQFGVTRVEL
GVQTLYNHIYKRVDRGHKIQDVIEANQLLRDSGIKVAMHMMPGLLSSFSSDVNMFKRLFNEPLFSPDMLKIYPCLVTEGS
EFYDMWKKGEYEPYTSQQAVDLIVEVKKILPKWVRTMRIQRDIPATLIDAGVKKSNLGELVYNRLEEEDIQCQCIRCREV
GHKKAHGIEPDYNNIELLRTDYDVVGGHEIFLSIEDVENDILIGFTRLRIPSNRVFRKEITSSSSLIRELHVYGQMQKIG
KNDDNLWQHKGYGAQLLEEAEKIAKDEYNKNKMLIISGIGVRDYYRKFGYYKDGPYMSKFI

Sequences:

>Translated_541_residues
MQEACRLIIEEALSRNITTKKDLEKLKIQTCRDLKLSGFMSNSKILQYAKPEELESLRPILMKKPTRTISGVAIVAVMCR
PHKCPHGRCKYCPESSIAPPSYTGEEPAALRARMFHFHPYVQTFNRLYQLKNIGHSIDKVELIIMGGTFASCTLDYQEWF
VTQCLRAMNDFETVSKKIPVNQREIKIIPPEDFQYIHDAQKNNEHSKVRCIGLTFETRPDYAKMEDINRMLQFGVTRVEL
GVQTLYNHIYKRVDRGHKIQDVIEANQLLRDSGIKVAMHMMPGLLSSFSSDVNMFKRLFNEPLFSPDMLKIYPCLVTEGS
EFYDMWKKGEYEPYTSQQAVDLIVEVKKILPKWVRTMRIQRDIPATLIDAGVKKSNLGELVYNRLEEEDIQCQCIRCREV
GHKKAHGIEPDYNNIELLRTDYDVVGGHEIFLSIEDVENDILIGFTRLRIPSNRVFRKEITSSSSLIRELHVYGQMQKIG
KNDDNLWQHKGYGAQLLEEAEKIAKDEYNKNKMLIISGIGVRDYYRKFGYYKDGPYMSKFI
>Mature_541_residues
MQEACRLIIEEALSRNITTKKDLEKLKIQTCRDLKLSGFMSNSKILQYAKPEELESLRPILMKKPTRTISGVAIVAVMCR
PHKCPHGRCKYCPESSIAPPSYTGEEPAALRARMFHFHPYVQTFNRLYQLKNIGHSIDKVELIIMGGTFASCTLDYQEWF
VTQCLRAMNDFETVSKKIPVNQREIKIIPPEDFQYIHDAQKNNEHSKVRCIGLTFETRPDYAKMEDINRMLQFGVTRVEL
GVQTLYNHIYKRVDRGHKIQDVIEANQLLRDSGIKVAMHMMPGLLSSFSSDVNMFKRLFNEPLFSPDMLKIYPCLVTEGS
EFYDMWKKGEYEPYTSQQAVDLIVEVKKILPKWVRTMRIQRDIPATLIDAGVKKSNLGELVYNRLEEEDIQCQCIRCREV
GHKKAHGIEPDYNNIELLRTDYDVVGGHEIFLSIEDVENDILIGFTRLRIPSNRVFRKEITSSSSLIRELHVYGQMQKIG
KNDDNLWQHKGYGAQLLEEAEKIAKDEYNKNKMLIISGIGVRDYYRKFGYYKDGPYMSKFI

Specific function: Unknown

COG id: COG1243

COG function: function code KB; Histone acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23510283, Length=531, Percent_Identity=40.8662900188324, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI133955098, Length=553, Percent_Identity=40.1446654611212, Blast_Score=406, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6325171, Length=549, Percent_Identity=40.4371584699454, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI19920684, Length=548, Percent_Identity=40.5109489051095, Blast_Score=400, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR006638
- InterPro:   IPR005910
- InterPro:   IPR007197 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 62787; Mature: 62787

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEACRLIIEEALSRNITTKKDLEKLKIQTCRDLKLSGFMSNSKILQYAKPEELESLRPI
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCEECCCCHHHHHHHHH
LMKKPTRTISGVAIVAVMCRPHKCPHGRCKYCPESSIAPPSYTGEEPAALRARMFHFHPY
HHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VQTFNRLYQLKNIGHSIDKVELIIMGGTFASCTLDYQEWFVTQCLRAMNDFETVSKKIPV
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
NQREIKIIPPEDFQYIHDAQKNNEHSKVRCIGLTFETRPDYAKMEDINRMLQFGVTRVEL
CCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHH
GVQTLYNHIYKRVDRGHKIQDVIEANQLLRDSGIKVAMHMMPGLLSSFSSDVNMFKRLFN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
EPLFSPDMLKIYPCLVTEGSEFYDMWKKGEYEPYTSQQAVDLIVEVKKILPKWVRTMRIQ
CCCCCCCHHEEEEEHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDIPATLIDAGVKKSNLGELVYNRLEEEDIQCQCIRCREVGHKKAHGIEPDYNNIELLRT
CCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCCCCCCCCEEEEEE
DYDVVGGHEIFLSIEDVENDILIGFTRLRIPSNRVFRKEITSSSSLIRELHVYGQMQKIG
CCCEECCEEEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNDDNLWQHKGYGAQLLEEAEKIAKDEYNKNKMLIISGIGVRDYYRKFGYYKDGPYMSKF
CCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHC
I
C
>Mature Secondary Structure
MQEACRLIIEEALSRNITTKKDLEKLKIQTCRDLKLSGFMSNSKILQYAKPEELESLRPI
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCEECCCCHHHHHHHHH
LMKKPTRTISGVAIVAVMCRPHKCPHGRCKYCPESSIAPPSYTGEEPAALRARMFHFHPY
HHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VQTFNRLYQLKNIGHSIDKVELIIMGGTFASCTLDYQEWFVTQCLRAMNDFETVSKKIPV
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCC
NQREIKIIPPEDFQYIHDAQKNNEHSKVRCIGLTFETRPDYAKMEDINRMLQFGVTRVEL
CCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHH
GVQTLYNHIYKRVDRGHKIQDVIEANQLLRDSGIKVAMHMMPGLLSSFSSDVNMFKRLFN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
EPLFSPDMLKIYPCLVTEGSEFYDMWKKGEYEPYTSQQAVDLIVEVKKILPKWVRTMRIQ
CCCCCCCHHEEEEEHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDIPATLIDAGVKKSNLGELVYNRLEEEDIQCQCIRCREVGHKKAHGIEPDYNNIELLRT
CCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCCCCCCCCEEEEEE
DYDVVGGHEIFLSIEDVENDILIGFTRLRIPSNRVFRKEITSSSSLIRELHVYGQMQKIG
CCCEECCEEEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNDDNLWQHKGYGAQLLEEAEKIAKDEYNKNKMLIISGIGVRDYYRKFGYYKDGPYMSKF
CCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]