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The map label for this gene is moeZ [H]

Identifier: 84489058

GI number: 84489058

Start: 288613

End: 289347

Strand: Direct

Name: moeZ [H]

Synonym: Msp_0231

Alternate gene names: 84489058

Gene position: 288613-289347 (Clockwise)

Preceding gene: 84489057

Following gene: 84489059

Centisome position: 16.33

GC content: 27.07

Gene sequence:

>735_bases
ATGACAGAATTATATAATCAAATGATTTCAAGACAAAAAGAAATATTTACAGAAAATCAACAGGAAAAAATTAGAAACAC
ACCTGTTTTAGTAATAGGTTGTGGAGGACTTGGTGGAACAGTAATAGAACAGTTAGTAAGGGCAGGTTTTGAAAATTTAA
CAATTGTAGATCAAGATGTTTTTGATAAAACTAATTTAAATCGTCAAATAAGAAGTAATTTAGATACAATAGATAAATCT
AAAGTAGAAACAGCAAAAAAGGAATCATTAAAAATAAATCCTAACTTAAATATTACAGGATATGATACTACTATTACTCC
AGAAAACATATCTCAAATCTTTAAAGGAAATGATATTGTAATTGATGCTGTAGATAATGTATATACTAGGGTGATGATAT
CAAGGGAAGCAAGAAAACAAAATATGGCATTTATTCATTGTGCAGTAGAAACAACTGTGGGACAACTAACTATAATTACC
AATGATACTCCATCATATGAGGAATTATTTAAATTAAAATCTAATGGAAAAACACTTGATAAATCAAAAGAATATCTACT
AGGTATAAGTACTAAAAAACCACAAGTTCTAGGAACAACACCTGCAATATTTGGAGCATTAGAAGTTAATGAAACTATTA
AATATATATTAGAAAGTAAGGATGCTCTTTTTGCACCAAAAGTATTGTTATGGGATATATTTGATATGACATCATTTAGG
ATAATTGATTTTTAA

Upstream 100 bases:

>100_bases
TATTTTTTATATTAGAAAATATAACAATTGTTATATATTTTAAGTTTTTAATATAGTATATAATTAAATAAGATCATCTA
GTAAAAAAAGGAGATTATCT

Downstream 100 bases:

>100_bases
ATGATACTAATGTATATTTACTTATTATTAAATATACTAAAACTTCACATAACTTTTTTTAACTACCTTTTTTTATACAT
ATAAAAAGAAATATTATCGA

Product: E1-like enzyme

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTELYNQMISRQKEIFTENQQEKIRNTPVLVIGCGGLGGTVIEQLVRAGFENLTIVDQDVFDKTNLNRQIRSNLDTIDKS
KVETAKKESLKINPNLNITGYDTTITPENISQIFKGNDIVIDAVDNVYTRVMISREARKQNMAFIHCAVETTVGQLTIIT
NDTPSYEELFKLKSNGKTLDKSKEYLLGISTKKPQVLGTTPAIFGALEVNETIKYILESKDALFAPKVLLWDIFDMTSFR
IIDF

Sequences:

>Translated_244_residues
MTELYNQMISRQKEIFTENQQEKIRNTPVLVIGCGGLGGTVIEQLVRAGFENLTIVDQDVFDKTNLNRQIRSNLDTIDKS
KVETAKKESLKINPNLNITGYDTTITPENISQIFKGNDIVIDAVDNVYTRVMISREARKQNMAFIHCAVETTVGQLTIIT
NDTPSYEELFKLKSNGKTLDKSKEYLLGISTKKPQVLGTTPAIFGALEVNETIKYILESKDALFAPKVLLWDIFDMTSFR
IIDF
>Mature_243_residues
TELYNQMISRQKEIFTENQQEKIRNTPVLVIGCGGLGGTVIEQLVRAGFENLTIVDQDVFDKTNLNRQIRSNLDTIDKSK
VETAKKESLKINPNLNITGYDTTITPENISQIFKGNDIVIDAVDNVYTRVMISREARKQNMAFIHCAVETTVGQLTIITN
DTPSYEELFKLKSNGKTLDKSKEYLLGISTKKPQVLGTTPAIFGALEVNETIKYILESKDALFAPKVLLWDIFDMTSFRI
IDF

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=148, Percent_Identity=31.0810810810811, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7657339, Length=162, Percent_Identity=26.5432098765432, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787048, Length=239, Percent_Identity=26.3598326359833, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789177, Length=146, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082356, Length=148, Percent_Identity=30.4054054054054, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=220, Percent_Identity=30, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203301, Length=150, Percent_Identity=30, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=223, Percent_Identity=30.0448430493274, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582879, Length=218, Percent_Identity=29.8165137614679, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24660640, Length=146, Percent_Identity=32.8767123287671, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573937, Length=156, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27550; Mature: 27419

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELYNQMISRQKEIFTENQQEKIRNTPVLVIGCGGLGGTVIEQLVRAGFENLTIVDQDV
CHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHH
FDKTNLNRQIRSNLDTIDKSKVETAKKESLKINPNLNITGYDTTITPENISQIFKGNDIV
HCCCCCCHHHHHCCCHHHHHHHHHHHHCCEEECCCEEEEECCCEECHHHHHHHHCCCCEE
IDAVDNVYTRVMISREARKQNMAFIHCAVETTVGQLTIITNDTPSYEELFKLKSNGKTLD
EECHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCC
KSKEYLLGISTKKPQVLGTTPAIFGALEVNETIKYILESKDALFAPKVLLWDIFDMTSFR
CCCCEEEEECCCCCEEEECCHHHEEEEEHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCEE
IIDF
EECC
>Mature Secondary Structure 
TELYNQMISRQKEIFTENQQEKIRNTPVLVIGCGGLGGTVIEQLVRAGFENLTIVDQDV
HHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEHHH
FDKTNLNRQIRSNLDTIDKSKVETAKKESLKINPNLNITGYDTTITPENISQIFKGNDIV
HCCCCCCHHHHHCCCHHHHHHHHHHHHCCEEECCCEEEEECCCEECHHHHHHHHCCCCEE
IDAVDNVYTRVMISREARKQNMAFIHCAVETTVGQLTIITNDTPSYEELFKLKSNGKTLD
EECHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCC
KSKEYLLGISTKKPQVLGTTPAIFGALEVNETIKYILESKDALFAPKVLLWDIFDMTSFR
CCCCEEEEECCCCCEEEECCHHHEEEEEHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCEE
IIDF
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]