BacMap

Definition	Methanosphaera stadtmanae DSM 3091 chromosome, complete genome.
Accession	NC_007681
Length	1,767,403

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The map label for this gene is abcA [H]

Identifier: 84489033

GI number: 84489033

Start: 252492

End: 253241

Strand: Direct

Name: abcA [H]

Synonym: Msp_0205

Alternate gene names: 84489033

Gene position: 252492-253241 (Clockwise)

Preceding gene: 84489032

Following gene: 84489034

Centisome position: 14.29

GC content: 31.2

Gene sequence:

>750_bases
TTGGATAAAAATAAGGTAGTTATTGATGTGGAAGATGTGGCTATGAAATTTAATTTAGGCCAGGAAAAAACAGATAACTT
TAAGGAATTTGTAATTAAAGCACTGAAAAAAGAACTTCTTTTTCAGCCATTTTGGGCATTAAAAGGAGTTTCATTTAAGA
TTCATAAGGGTGAAAAGGTAGCATTCATAGGTTCAAATGGTGCTGGAAAAAGTACATTATTAAAAATCATAGCAGGAGTT
ATGAAACCAACAGAAGGTTCTGTTGAAGTACATGGTCGTATAGCACCACTTTTAGCACTAGGAGCAGGTTTTGATTATAA
TTATACTGGTAGTGAAAATATTTTCCTTAATGGATCTTTTCTTGGATACTCTAAACAATATATGCATGATAAGTATGATG
AAATAGTTGAATTTTCAGAAATTGGTGATTTTATTGATGTTCCTGTAAAAAACTATTCATCAGGTATGAAATCTCGTCTA
GCATTTTCAATAGCAACAACAGTAAAATCTCAGATACTTATATTAGATGAAGTATTGTCTGTGGGTGATGCAGCATTTAA
GGCTAAATCAACTAAAAGAATGAAAGAAATGATGGCTGGGGATGTTACATTACTATTTGTATCACATTCAATCTCTCAAG
TAAAAGAATTATGTGATAGAGCAATATGGCTTGATCATGGAAAAGTACTTATGGATGGAGAAGTTAATGAAGTCTGTGAT
AAATACCTTGAATTTGTAAGAAATAAATAG

Upstream 100 bases:

>100_bases
TATCAGGTCTTGTATTTCTGGTATTAGGACTGTTCTTATTATATAAATTTCAGGATAAATTTGTATTATATGTATAAATA
TTTTGTAGGAGGAAAGTGTT

Downstream 100 bases:

>100_bases
ATTCTATATCTATTCTATTTTTCTTAAGAAAAAAACTTTTTTTTAGGTTTTGTTATAATGAACAAATCAGATAATAAAAT
AACAGTTATAATTCCCAATT

Product: polysaccharide/polyol phosphate ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MDKNKVVIDVEDVAMKFNLGQEKTDNFKEFVIKALKKELLFQPFWALKGVSFKIHKGEKVAFIGSNGAGKSTLLKIIAGV
MKPTEGSVEVHGRIAPLLALGAGFDYNYTGSENIFLNGSFLGYSKQYMHDKYDEIVEFSEIGDFIDVPVKNYSSGMKSRL
AFSIATTVKSQILILDEVLSVGDAAFKAKSTKRMKEMMAGDVTLLFVSHSISQVKELCDRAIWLDHGKVLMDGEVNEVCD
KYLEFVRNK

Sequences:

>Translated_249_residues
MDKNKVVIDVEDVAMKFNLGQEKTDNFKEFVIKALKKELLFQPFWALKGVSFKIHKGEKVAFIGSNGAGKSTLLKIIAGV
MKPTEGSVEVHGRIAPLLALGAGFDYNYTGSENIFLNGSFLGYSKQYMHDKYDEIVEFSEIGDFIDVPVKNYSSGMKSRL
AFSIATTVKSQILILDEVLSVGDAAFKAKSTKRMKEMMAGDVTLLFVSHSISQVKELCDRAIWLDHGKVLMDGEVNEVCD
KYLEFVRNK
>Mature_249_residues
MDKNKVVIDVEDVAMKFNLGQEKTDNFKEFVIKALKKELLFQPFWALKGVSFKIHKGEKVAFIGSNGAGKSTLLKIIAGV
MKPTEGSVEVHGRIAPLLALGAGFDYNYTGSENIFLNGSFLGYSKQYMHDKYDEIVEFSEIGDFIDVPVKNYSSGMKSRL
AFSIATTVKSQILILDEVLSVGDAAFKAKSTKRMKEMMAGDVTLLFVSHSISQVKELCDRAIWLDHGKVLMDGEVNEVCD
KYLEFVRNK

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27477115, Length=220, Percent_Identity=31.3636363636364, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=25.2475247524752, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI153792144, Length=215, Percent_Identity=27.4418604651163, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI150417984, Length=209, Percent_Identity=26.7942583732057, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31657092, Length=218, Percent_Identity=27.0642201834862, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157502201, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI157502203, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI6005701, Length=205, Percent_Identity=25.8536585365854, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116734710, Length=195, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45446740, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI47078218, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI30795238, Length=217, Percent_Identity=23.0414746543779, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27262624, Length=238, Percent_Identity=25.2100840336134, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27262626, Length=238, Percent_Identity=25.2100840336134, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI89111135, Length=217, Percent_Identity=27.1889400921659, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27881501, Length=217, Percent_Identity=23.0414746543779, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994943, Length=224, Percent_Identity=27.6785714285714, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790467, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786398, Length=215, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788761, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081782, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48995001, Length=244, Percent_Identity=28.2786885245902, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790525, Length=225, Percent_Identity=24, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=24.0196078431373, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787041, Length=210, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=20.7373271889401, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=206, Percent_Identity=23.7864077669903, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786319, Length=196, Percent_Identity=23.9795918367347, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788210, Length=194, Percent_Identity=29.8969072164948, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510237, Length=225, Percent_Identity=24.8888888888889, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=214, Percent_Identity=26.1682242990654, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=224, Percent_Identity=22.7678571428571, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=210, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567243, Length=204, Percent_Identity=26.9607843137255, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321720, Length=206, Percent_Identity=28.6407766990291, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=224, Percent_Identity=25.8928571428571, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI116007184, Length=224, Percent_Identity=25.8928571428571, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI161077321, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653245, Length=224, Percent_Identity=28.125, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363262, Length=224, Percent_Identity=28.125, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649703, Length=227, Percent_Identity=23.7885462555066, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573573, Length=229, Percent_Identity=22.2707423580786, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573571, Length=229, Percent_Identity=22.2707423580786, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27772; Mature: 27772

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNKVVIDVEDVAMKFNLGQEKTDNFKEFVIKALKKELLFQPFWALKGVSFKIHKGEKV
CCCCEEEEEHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCEE
AFIGSNGAGKSTLLKIIAGVMKPTEGSVEVHGRIAPLLALGAGFDYNYTGSENIFLNGSF
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCEEEEECCC
LGYSKQYMHDKYDEIVEFSEIGDFIDVPVKNYSSGMKSRLAFSIATTVKSQILILDEVLS
CCCCHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGDAAFKAKSTKRMKEMMAGDVTLLFVSHSISQVKELCDRAIWLDHGKVLMDGEVNEVCD
HCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHEEECCCCEEECCCHHHHHH
KYLEFVRNK
HHHHHHCCC
>Mature Secondary Structure
MDKNKVVIDVEDVAMKFNLGQEKTDNFKEFVIKALKKELLFQPFWALKGVSFKIHKGEKV
CCCCEEEEEHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCEE
AFIGSNGAGKSTLLKIIAGVMKPTEGSVEVHGRIAPLLALGAGFDYNYTGSENIFLNGSF
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCEEEEECCC
LGYSKQYMHDKYDEIVEFSEIGDFIDVPVKNYSSGMKSRLAFSIATTVKSQILILDEVLS
CCCCHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGDAAFKAKSTKRMKEMMAGDVTLLFVSHSISQVKELCDRAIWLDHGKVLMDGEVNEVCD
HCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHEEECCCCEEECCCHHHHHH
KYLEFVRNK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]