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The map label for this gene is hmuU [H]

Identifier: 83721599

GI number: 83721599

Start: 1596093

End: 1597193

Strand: Direct

Name: hmuU [H]

Synonym: BTH_I1415

Alternate gene names: 83721599

Gene position: 1596093-1597193 (Clockwise)

Preceding gene: 83719141

Following gene: 83720879

Centisome position: 41.9

GC content: 74.3

Gene sequence:

>1101_bases
ATGAGCGGCGCGGCGCGCGCCGACGCACCGCCGGCATCGCGCGGCCGTCGATGGCGCGTGCGGCTCGTGCTGCCCGCGCT
TGCGGTGCTCGTCGCGATTTCGATCGTCGCGTCGACCGCGCTCGGCGCGACGACGATCGCGCCGGCGCGGGTCGTCGCGA
TCGTGTTGTCGCATCTCGCGGACCTGCGCGTCACGAATGCGCATGTCGCCCACGCGCATGCTGCCGACACGCTCGCCCGG
AGCGGCGCATCGTTCGCCGAAGACAGCATCGTCTGGCAGATCAGATTGCCGCGCGCGCTGCTCGCGGCGCTCGTCGGCGC
GACGCTCGCGATGGTCGGCGTCGCGCTGCAGGCGGCGACCGCGAACCGGCTCGCCGACCCGCACCTGCTTGGCGTGAGCT
CGGGCGCGATGCTTGGCGCGGTGGCGGCGACGCTCGGCCTCGGCGCCGCGTTCGGGCCGTTCACGCTGTCGTTCGCGGCG
TTCGCGGGCGCGCTCGCCGCCACCGCGCTCGTGATCGCGCTCGCATACCGGCGCGGCCGGCTCGAGGCGGACCGGTTGCT
GCTCGCGGGCGTCGCGGTGTCGTTCATGATGACCGCGCTCGCGAACCTGCTGCTGTATCTCGGCGATCCGCGCGCCGCGT
CGTCCGTGCTGTTCTGGATGCTGGGCGGCGTCGGGCTCGCGCGCTGGGATCTGCTCGCCGCGCCCGCATGCTGCGCGGCG
CTCGCGGCGCTGCTGCTCTTCGCGCGCCGGCGCGAACTAAACGCGCTGATGTCGGGCGACGTCGCGGCGGTGTCGCTCGG
CGTGCCCGTCGCGCGGATGCGTCGTGAGGTGTTCGTGATCGCTTCGTTCGCGACGGGCGCGATGGTCGCGGTGAGCGGCG
CGATCGGCTTCGTCGGGCTCGTGACGCCGCATCTGTGCCGGCGGCTCGTCGGTGCGGAGCATGCCCGGCTGCTGCCGGTC
GCCGGGTTGAGCGGCGCGGCGTTGCTCGTGTGGGCCGACGTCGCCGCGCGCACGCTCGCCGCGCCGGAGGATCTGCCGAT
CGGCATCGTGACCGCGGGGCTCGGCGGCGCGTTCTTCGTTGTGCTGATGCGGCGGCGGTGA

Upstream 100 bases:

>100_bases
TGATTCCGTACGATGCGGCGACGCCCGGCGTCGAGAACGCGGCGGCCGTCGAGACGATCGCGCGCGGCCTGCATCCGCGC
GCGTTCGCGAAGGCCGCGCG

Downstream 100 bases:

>100_bases
GCGCAGGCGCGCGGCGAATCGAGGCGTCGCGCGTCGCATGGCGCGATCGCGCGCGCCGCGTTCGCCGGCTCTCAGCGCCG
CTTTCCGCGCAAAGTCAGTT

Product: iron compound ABC transporter permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSGAARADAPPASRGRRWRVRLVLPALAVLVAISIVASTALGATTIAPARVVAIVLSHLADLRVTNAHVAHAHAADTLAR
SGASFAEDSIVWQIRLPRALLAALVGATLAMVGVALQAATANRLADPHLLGVSSGAMLGAVAATLGLGAAFGPFTLSFAA
FAGALAATALVIALAYRRGRLEADRLLLAGVAVSFMMTALANLLLYLGDPRAASSVLFWMLGGVGLARWDLLAAPACCAA
LAALLLFARRRELNALMSGDVAAVSLGVPVARMRREVFVIASFATGAMVAVSGAIGFVGLVTPHLCRRLVGAEHARLLPV
AGLSGAALLVWADVAARTLAAPEDLPIGIVTAGLGGAFFVVLMRRR

Sequences:

>Translated_366_residues
MSGAARADAPPASRGRRWRVRLVLPALAVLVAISIVASTALGATTIAPARVVAIVLSHLADLRVTNAHVAHAHAADTLAR
SGASFAEDSIVWQIRLPRALLAALVGATLAMVGVALQAATANRLADPHLLGVSSGAMLGAVAATLGLGAAFGPFTLSFAA
FAGALAATALVIALAYRRGRLEADRLLLAGVAVSFMMTALANLLLYLGDPRAASSVLFWMLGGVGLARWDLLAAPACCAA
LAALLLFARRRELNALMSGDVAAVSLGVPVARMRREVFVIASFATGAMVAVSGAIGFVGLVTPHLCRRLVGAEHARLLPV
AGLSGAALLVWADVAARTLAAPEDLPIGIVTAGLGGAFFVVLMRRR
>Mature_365_residues
SGAARADAPPASRGRRWRVRLVLPALAVLVAISIVASTALGATTIAPARVVAIVLSHLADLRVTNAHVAHAHAADTLARS
GASFAEDSIVWQIRLPRALLAALVGATLAMVGVALQAATANRLADPHLLGVSSGAMLGAVAATLGLGAAFGPFTLSFAAF
AGALAATALVIALAYRRGRLEADRLLLAGVAVSFMMTALANLLLYLGDPRAASSVLFWMLGGVGLARWDLLAAPACCAAL
AALLLFARRRELNALMSGDVAAVSLGVPVARMRREVFVIASFATGAMVAVSGAIGFVGLVTPHLCRRLVGAEHARLLPVA
GLSGAALLVWADVAARTLAAPEDLPIGIVTAGLGGAFFVVLMRRR

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=40.9252669039146, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=37.0629370629371, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1790740, Length=285, Percent_Identity=38.5964912280702, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786805, Length=288, Percent_Identity=36.4583333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786804, Length=276, Percent_Identity=34.4202898550725, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=32.404181184669, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37339; Mature: 37208

Theoretical pI: Translated: 12.04; Mature: 12.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAARADAPPASRGRRWRVRLVLPALAVLVAISIVASTALGATTIAPARVVAIVLSHLA
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLRVTNAHVAHAHAADTLARSGASFAEDSIVWQIRLPRALLAALVGATLAMVGVALQAAT
HHEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ANRLADPHLLGVSSGAMLGAVAATLGLGAAFGPFTLSFAAFAGALAATALVIALAYRRGR
HHHCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LEADRLLLAGVAVSFMMTALANLLLYLGDPRAASSVLFWMLGGVGLARWDLLAAPACCAA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LAALLLFARRRELNALMSGDVAAVSLGVPVARMRREVFVIASFATGAMVAVSGAIGFVGL
HHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHH
VTPHLCRRLVGAEHARLLPVAGLSGAALLVWADVAARTLAAPEDLPIGIVTAGLGGAFFV
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH
VLMRRR
HHHCCC
>Mature Secondary Structure 
SGAARADAPPASRGRRWRVRLVLPALAVLVAISIVASTALGATTIAPARVVAIVLSHLA
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLRVTNAHVAHAHAADTLARSGASFAEDSIVWQIRLPRALLAALVGATLAMVGVALQAAT
HHEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
ANRLADPHLLGVSSGAMLGAVAATLGLGAAFGPFTLSFAAFAGALAATALVIALAYRRGR
HHHCCCCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LEADRLLLAGVAVSFMMTALANLLLYLGDPRAASSVLFWMLGGVGLARWDLLAAPACCAA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LAALLLFARRRELNALMSGDVAAVSLGVPVARMRREVFVIASFATGAMVAVSGAIGFVGL
HHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHH
VTPHLCRRLVGAEHARLLPVAGLSGAALLVWADVAARTLAAPEDLPIGIVTAGLGGAFFV
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH
VLMRRR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]