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The map label for this gene is fabD-1 [H]

Identifier: 83721554

GI number: 83721554

Start: 1927412

End: 1928341

Strand: Direct

Name: fabD-1 [H]

Synonym: BTH_I1718

Alternate gene names: 83721554

Gene position: 1927412-1928341 (Clockwise)

Preceding gene: 83719007

Following gene: 83720590

Centisome position: 50.6

GC content: 68.71

Gene sequence:

>930_bases
ATGAAATTTGCATTCGTTTTTCCGGGCCAGGGCTCGCAATCGGTCGGCATGCTCAATGCATTCGCCGATGTCGCCGTCGT
GCGCGAGACGCTCGACGAGGCGTCTGATGCGCTCGGGCAGGATATCGGCAAGCTGATCGCCGACGGCCCGGCCGACGAAC
TCAATCTGACGACGAATACGCAACCCGTGATGCTGACGGCCGCGTATGCGTGCTATCGCGCGTGGCAGCAGGCGGGCGGC
GCGCAGCCGTCGATCGTCGCGGGCCACAGCCTCGGCGAATACACGGCGCTCGTCGCCGCGGGCGCGATCGCGTTTCGCGA
CGCGCTTCCGCTCGTGCGCTTTCGCGCGCAGGCGATGCAGACGGCCGTGCCCGTCGGCGTCGGCGGCATGGCGGCGATTC
TCGGCCTCGACGACGATACGGTGCGCGCAGTGTGCGCCGAGGCGTCGGCGGCGGGCGTCGTCGAAGCGGTGAATTTCAAT
GCGCCCGCGCAGGTCGTGATCGCGGGCACGAAGGCGGGCATCGAGATGGCCTGCGAGATCGCGAAGGCGAAGGGCGCGAA
GCGCGCGCTGCCTCTGCCCGTGTCGGCGCCGTTCCACTCGTCGCTGCTCAAGCCTGCCTCGGACAAGCTGCGCGACTATC
TCGCGAACGTCGACGTGAAGACGCCGCGGATTCCCGTCGTCAACAACATCGACGTCGCGGTGGTGTCCGATCCCGCCGCG
ATCAAGGATGCGCTCGTGCGGCAGGCGGCGGGCCCCGTGCGCTGGGTCGAGTGCGTGCGGCACATCGCCCGCGAGGGTGC
GACGCACGTGATCGAGTGCGGTCCGGGCAAGGTGCTCGCCGGCCTCACGAAGCGTATCGACAGCAACCTGGTCGGCGCGT
CGGTGTTCGATCCGGCGTCGCTCGACGAAGCGCTCAAGCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
GTGGGGCGCGTCGGTCTTCCGGTACTGAGCCGCACGTCTCGCGCATCCCATCGGCGCGCCGCTCGCGCGCGCCGCTCGAA
TCGATTCAATTGGGGACGAT

Downstream 100 bases:

>100_bases
CGCCGTCAAGCGCTCGAGCTTGCCGATTCAACCGAAACACGGAACCTCTGCATGGACAAGACTCTCGACAAACAAGTCGC
GATCGTCACCGGCGCGTCGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASAAGVVEAVNFN
APAQVVIAGTKAGIEMACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLRDYLANVDVKTPRIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAREGATHVIECGPGKVLAGLTKRIDSNLVGASVFDPASLDEALKLAA

Sequences:

>Translated_309_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASAAGVVEAVNFN
APAQVVIAGTKAGIEMACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLRDYLANVDVKTPRIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAREGATHVIECGPGKVLAGLTKRIDSNLVGASVFDPASLDEALKLAA
>Mature_309_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASAAGVVEAVNFN
APAQVVIAGTKAGIEMACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLRDYLANVDVKTPRIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAREGATHVIECGPGKVLAGLTKRIDSNLVGASVFDPASLDEALKLAA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=32.2259136212625, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=39.2523364485981, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=54.7231270358306, Blast_Score=313, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.0580204778157, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=234, Percent_Identity=31.6239316239316, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=30.5194805194805, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31873; Mature: 31873

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QPVMLTAAYACYRAWQQAGGAQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGVGGMAAILGLDDDTVRAVCAEASAAGVVEAVNFNAPAQVVIAGTKAGIEMACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDKLRDYLANVDVKTPRIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHH
IKDALVRQAAGPVRWVECVRHIAREGATHVIECGPGKVLAGLTKRIDSNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
LDEALKLAA
HHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QPVMLTAAYACYRAWQQAGGAQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGVGGMAAILGLDDDTVRAVCAEASAAGVVEAVNFNAPAQVVIAGTKAGIEMACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDKLRDYLANVDVKTPRIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHH
IKDALVRQAAGPVRWVECVRHIAREGATHVIECGPGKVLAGLTKRIDSNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
LDEALKLAA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]