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The map label for this gene is moeA [H]

Identifier: 83721467

GI number: 83721467

Start: 1912157

End: 1913455

Strand: Reverse

Name: moeA [H]

Synonym: BTH_I1704

Alternate gene names: 83721467

Gene position: 1913455-1912157 (Counterclockwise)

Preceding gene: 83719973

Following gene: 83718971

Centisome position: 50.23

GC content: 73.52

Gene sequence:

>1299_bases
ATGACCACGCACACCACGCCCACGCCATCCGCCACGCCCGAGCACGCCGTCGCGCTGACCGTCGACGAAGCGCGCGCGCT
CGCGTTGCGCTTCGCCGAACGCGTCGCGCAGGTCGAGCGCGTCGCGTTGCGCGACGCGCTCGGCCGCGTGCTCGCCGACG
ATATCGCGTCGCCATTCGACATTCCCGCATACGACAACGCCGCGATGGACGGCTACGCGTTCGACGGCGCGGCGCTCGCC
GCACCCGCCGCCGACGGCATGCTGACGCTCGCAGTAGCGGGCCGCGCGCTCGCGGGACATCCGTTCGACGGCCCCCGCGT
CGCGAAAGACGCGTGCGTGCGAATCATGACGGGCGCGCAGATGCCCACAGGCTGCGACACCGTGATCCCGCAGGAAAAAG
TCGAGGCGACGAACGACGTCGCGCGCTTTCCGGCCTCGGCCGCCGCGCGCGGAGACCACTGCCGACGCGCGGGCGAAGAT
CTCGCGCGCGGCGCGAGCGCGCTCGCCGCCGGCCGCCTCGTGCGCGCGGCCGATCTCGGCCTGCTCGCGTCGCTCGGCAT
CGCCGACGTCACGGTGCGCCGCCGCGTGCGCGTCGCGTTCTTCTCGACGGGCGATGAACTGCAGACGCCGGGCGAGCCGC
TGCGCGAAGGCGGCCTCTACGACAGCAACCGCGCGACGCTCGTCGGGATGCTCGCCCGCCTCGGCGTCGAGACGCTCGAT
CTCGGCATCGTTCGCGACAACCCCGCCGCGCTCGAAAGCGCACTGAAGACAGCGGCCGCGCAGGCGGACGCGGTCATCAC
GTCGGGCGGCGTGTCGGTCGGCGACGCGGACTTCACTCGCGCGCTGCTGGAAACGCTCGGCGACGTCACGTTCGCGAGCG
TCGCGATGCGCCCGGGCCGTCCGCTCGCGTGCGGACGGATCTGGGCAAGCGGGCGCGCCGGGCGGCCCGCGCTCTTCTTC
GGCCTGCCGGGCAACCCGGTCGCGGTCGCGGCAACCTTCATCGTGATCGTGCGCGACGCGCTCCTCGCGATGATGGGCGC
CGACGCGCAGCCGCTCCCCCGCTACCCCGCCATCTGCGAGACGCCGCTCAAGAAGCGCGCGGGCCGCACCGAATATCTGC
GCGGCCACGCGGCACGCGACGCGAGCGGCGTGTGGCGCGTGGCGCCCGCCGGCTCGCAAAGCTCGGCATCGCTCAAGAGC
CTGAGCGACGCGAACTGCTTCATCGTGCTCGCGCACGACGCCGCGCGCGTCGACGCCGGCGCGACGGTCGACATCCTGCC
GTTCGACGGCGCCATCTGA

Upstream 100 bases:

>100_bases
GCGTTCCGCGCGCCGCCTGCCGCTTGCGACGCGAGCGCTTCACGGCGGCGGCCGGGATGCCGGCCCCGAACACAATCCGC
CTAGCGGCGCCTCGCCACCG

Downstream 100 bases:

>100_bases
ATCCGTTCTCAGCACTTCCACGGGGGCAACTCTCATATGAAAAAACAAATCTCATCGATCGCACCGGGGCAAACCGCGAA
AGCGCTGATCCTCGTCTATC

Product: molybdopterin biosynthesis moeA protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTTHTTPTPSATPEHAVALTVDEARALALRFAERVAQVERVALRDALGRVLADDIASPFDIPAYDNAAMDGYAFDGAALA
APAADGMLTLAVAGRALAGHPFDGPRVAKDACVRIMTGAQMPTGCDTVIPQEKVEATNDVARFPASAAARGDHCRRAGED
LARGASALAAGRLVRAADLGLLASLGIADVTVRRRVRVAFFSTGDELQTPGEPLREGGLYDSNRATLVGMLARLGVETLD
LGIVRDNPAALESALKTAAAQADAVITSGGVSVGDADFTRALLETLGDVTFASVAMRPGRPLACGRIWASGRAGRPALFF
GLPGNPVAVAATFIVIVRDALLAMMGADAQPLPRYPAICETPLKKRAGRTEYLRGHAARDASGVWRVAPAGSQSSASLKS
LSDANCFIVLAHDAARVDAGATVDILPFDGAI

Sequences:

>Translated_432_residues
MTTHTTPTPSATPEHAVALTVDEARALALRFAERVAQVERVALRDALGRVLADDIASPFDIPAYDNAAMDGYAFDGAALA
APAADGMLTLAVAGRALAGHPFDGPRVAKDACVRIMTGAQMPTGCDTVIPQEKVEATNDVARFPASAAARGDHCRRAGED
LARGASALAAGRLVRAADLGLLASLGIADVTVRRRVRVAFFSTGDELQTPGEPLREGGLYDSNRATLVGMLARLGVETLD
LGIVRDNPAALESALKTAAAQADAVITSGGVSVGDADFTRALLETLGDVTFASVAMRPGRPLACGRIWASGRAGRPALFF
GLPGNPVAVAATFIVIVRDALLAMMGADAQPLPRYPAICETPLKKRAGRTEYLRGHAARDASGVWRVAPAGSQSSASLKS
LSDANCFIVLAHDAARVDAGATVDILPFDGAI
>Mature_431_residues
TTHTTPTPSATPEHAVALTVDEARALALRFAERVAQVERVALRDALGRVLADDIASPFDIPAYDNAAMDGYAFDGAALAA
PAADGMLTLAVAGRALAGHPFDGPRVAKDACVRIMTGAQMPTGCDTVIPQEKVEATNDVARFPASAAARGDHCRRAGEDL
ARGASALAAGRLVRAADLGLLASLGIADVTVRRRVRVAFFSTGDELQTPGEPLREGGLYDSNRATLVGMLARLGVETLDL
GIVRDNPAALESALKTAAAQADAVITSGGVSVGDADFTRALLETLGDVTFASVAMRPGRPLACGRIWASGRAGRPALFFG
LPGNPVAVAATFIVIVRDALLAMMGADAQPLPRYPAICETPLKKRAGRTEYLRGHAARDASGVWRVAPAGSQSSASLKSL
SDANCFIVLAHDAARVDAGATVDILPFDGAI

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=408, Percent_Identity=32.5980392156863, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI66932975, Length=408, Percent_Identity=32.5980392156863, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1787049, Length=392, Percent_Identity=44.8979591836735, Blast_Score=310, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI25147659, Length=315, Percent_Identity=31.1111111111111, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562606, Length=371, Percent_Identity=26.4150943396226, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17136978, Length=413, Percent_Identity=26.634382566586, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638841, Length=413, Percent_Identity=26.634382566586, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 44666; Mature: 44535

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHTTPTPSATPEHAVALTVDEARALALRFAERVAQVERVALRDALGRVLADDIASPFD
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IPAYDNAAMDGYAFDGAALAAPAADGMLTLAVAGRALAGHPFDGPRVAKDACVRIMTGAQ
CCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCC
MPTGCDTVIPQEKVEATNDVARFPASAAARGDHCRRAGEDLARGASALAAGRLVRAADLG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLASLGIADVTVRRRVRVAFFSTGDELQTPGEPLREGGLYDSNRATLVGMLARLGVETLD
HHHHCCHHHHHHHHEEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCHHHEE
LGIVRDNPAALESALKTAAAQADAVITSGGVSVGDADFTRALLETLGDVTFASVAMRPGR
EEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCC
PLACGRIWASGRAGRPALFFGLPGNPVAVAATFIVIVRDALLAMMGADAQPLPRYPAICE
CCCHHHHEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHC
TPLKKRAGRTEYLRGHAARDASGVWRVAPAGSQSSASLKSLSDANCFIVLAHDAARVDAG
CHHHHHCCCHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEEEEECCCHHCCCC
ATVDILPFDGAI
CEEEEECCCCCC
>Mature Secondary Structure 
TTHTTPTPSATPEHAVALTVDEARALALRFAERVAQVERVALRDALGRVLADDIASPFD
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IPAYDNAAMDGYAFDGAALAAPAADGMLTLAVAGRALAGHPFDGPRVAKDACVRIMTGAQ
CCCCCCCCCCCCCCCCCHHCCCCCCCEEEEEECCCHHCCCCCCCCHHHHHHHHHHHHCCC
MPTGCDTVIPQEKVEATNDVARFPASAAARGDHCRRAGEDLARGASALAAGRLVRAADLG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLASLGIADVTVRRRVRVAFFSTGDELQTPGEPLREGGLYDSNRATLVGMLARLGVETLD
HHHHCCHHHHHHHHEEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCHHHEE
LGIVRDNPAALESALKTAAAQADAVITSGGVSVGDADFTRALLETLGDVTFASVAMRPGR
EEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCC
PLACGRIWASGRAGRPALFFGLPGNPVAVAATFIVIVRDALLAMMGADAQPLPRYPAICE
CCCHHHHEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHC
TPLKKRAGRTEYLRGHAARDASGVWRVAPAGSQSSASLKSLSDANCFIVLAHDAARVDAG
CHHHHHCCCHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEEEEECCCHHCCCC
ATVDILPFDGAI
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]