Click here to switch to the map view.

The map label for this gene is nudF [H]

Identifier: 83721454

GI number: 83721454

Start: 1218863

End: 1219453

Strand: Direct

Name: nudF [H]

Synonym: BTH_I1076

Alternate gene names: 83721454

Gene position: 1218863-1219453 (Clockwise)

Preceding gene: 83720714

Following gene: 83719166

Centisome position: 32.0

GC content: 62.61

Gene sequence:

>591_bases
ATGGCCGACTTGCCGAATCACGACGCCACCCTCACCGAAACTTGCATCGAAAGCGAGCCTGTCTACGACGGCTCGTTCCT
GAAGGTCAAGCGCGATACGGTTCGCTTGCCGGACGGCAAGCACGCGACGCGCGAATATGTGACGCATCCGGGCGCGGTGA
TGGTCATCCCGCTGTTCGACGACGGCCGTGTGCTGATGGAGAGCCAGTATCGCTACCCGATCGGCAAGGTGATGGCTGAA
TTTCCGGCGGGCAAGCTCGATCCGGACGAAGGCGCGCTCGCCTGCGCGGTTCGCGAATTGCGCGAGGAAACGGGCTACAC
CGCGCGCGAATACGTATTTCTCACGCGCATTCATCCGATCATTTCGTATTCGACCGAATTCATCGACATCTACCTCGCAC
GCGGCCTGACGGCGGGCGAGCGCAAGCTCGACGACGGCGAGTTCCTCGAGACGTTCACGGCGACGCTGCCGGACTTGCTC
GAATGGGTGCGCACCGGCCAGATCACCGACGTGAAGACGATCATCGGCACGATGTGGCTCGAGAAGGCGATGTCGGGCGC
ATGGCCGCTCGGCAGTGTGATCCGGCCGTAG

Upstream 100 bases:

>100_bases
CAGTCTCTTCGTGGTGTTTGCGTTTCCCGGCTTCACGTTCCAGTATCTCGTCAAACGGCGTTGACGGCGTAGGCCGTCGC
GCCCCACCGCGGAGCCGCCG

Downstream 100 bases:

>100_bases
CAGCGCGCCGAGCGGCCGATTTTGCGAAGGGATACAATCGGTGCCGTCGGCCGGCTCGATCGTGTTCTTTTTCGGACTGA
ATTTAGCACGACCGTTCAAA

Product: MutT/NUDIX NTP pyrophosphatase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MADLPNHDATLTETCIESEPVYDGSFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAE
FPAGKLDPDEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLL
EWVRTGQITDVKTIIGTMWLEKAMSGAWPLGSVIRP

Sequences:

>Translated_196_residues
MADLPNHDATLTETCIESEPVYDGSFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAE
FPAGKLDPDEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLL
EWVRTGQITDVKTIIGTMWLEKAMSGAWPLGSVIRP
>Mature_195_residues
ADLPNHDATLTETCIESEPVYDGSFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFDDGRVLMESQYRYPIGKVMAEF
PAGKLDPDEGALACAVRELREETGYTAREYVFLTRIHPIISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLE
WVRTGQITDVKTIIGTMWLEKAMSGAWPLGSVIRP

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 22000; Mature: 21869

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLPNHDATLTETCIESEPVYDGSFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFD
CCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCEEECCCCCHHHHHHHCCCCCEEEEEEEC
DGRVLMESQYRYPIGKVMAEFPAGKLDPDEGALACAVRELREETGYTAREYVFLTRIHPI
CCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHHHHHH
ISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLEWVRTGQITDVKTIIGTMWL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EKAMSGAWPLGSVIRP
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ADLPNHDATLTETCIESEPVYDGSFLKVKRDTVRLPDGKHATREYVTHPGAVMVIPLFD
CCCCCCCCHHHHHHHCCCCCCCCCEEEEECCEEECCCCCHHHHHHHCCCCCEEEEEEEC
DGRVLMESQYRYPIGKVMAEFPAGKLDPDEGALACAVRELREETGYTAREYVFLTRIHPI
CCCEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEHHHHHHHH
ISYSTEFIDIYLARGLTAGERKLDDGEFLETFTATLPDLLEWVRTGQITDVKTIIGTMWL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EKAMSGAWPLGSVIRP
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]