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The map label for this gene is nuoD [H]

Identifier: 83721170

GI number: 83721170

Start: 1205158

End: 1206411

Strand: Direct

Name: nuoD [H]

Synonym: BTH_I1064

Alternate gene names: 83721170

Gene position: 1205158-1206411 (Clockwise)

Preceding gene: 83719353

Following gene: 83720126

Centisome position: 31.64

GC content: 62.28

Gene sequence:

>1254_bases
ATGGCTGAAATCAAGAACTACACGCTCAACTTCGGTCCGCAGCACCCGGCCGCGCACGGCGTGCTGCGCCTCGTGCTTGA
GCTCGACGGCGAGGTGATCCAGCGCGCCGATCCGCACATTGGCCTCCTGCACCGCGCAACCGAGAAGCTTGCCGAAAGCA
AGACGTTCATCCAGTCCGTGCCGTACATGGACCGTCTCGACTATGTGTCGATGATGGTGAACGAACACGGCTACGTGCTC
GCGATCGAGAAACTGCTCGGCATCGAGGTGCCGGAGCGTGCGCAATACATCCGCGTGCTGTTCGACGAAATCACGCGCGT
GCTGAACCACCTGATGTGGATCGGTGCGCACGCGCTCGACGTCGGCGCGATGGCGGTGTTCCTCTATGCGTTCCGCGAGC
GCGAGGACCTGATGGACGTGTACGAGGCGGTGTCCGGCGCGCGCATGCACGCGGCGTACTATCGCCCGGGCGGCGTCTAT
CGCGATCTGCCGGAAGCGATGCCGCAATACAAAGCGTCGAAGATTCGAAACGAGCGTGCGCTCGCGAAGATGAACGAGGC
GCGCTCGGGTTCGGTGCTCGATTTCATCGACGATTTCTTCACGCGCTTCCCGAAGTGCGTCGACGAATACGAAACGCTGC
TGACCGATAACCGGATCTGGAAGCAGCGTCTCGTCGGCATCGGTGTCGTTTCGCCTGAGCGCGCGCTGCAGCTTGGCCTG
ACGGGCCCGATGATCCGCGGCTCCGGCATTGCATGGGATCTGCGCAAGAAGCAGCCGTACGAGGTGTACGACCGCATCGA
TTTCGACATCCCGGTGGGCGTGAACGGCGATTGCTACGACCGCTATCTGGTGCGGGTCGAGGAGATGCGCCAGTCGACGC
GTATCGCGAAACAATGTATTGAGTGGCTCCGCGAGAATCCCGGCCCCGTGATCACCGACAATCACAAGGTCGCGCCGCCG
TCGCGTGTCGGCATGAAGACGAACATGGAGGATCTGATCCACCATTTCAAGCTCTTCACCGAAGGTTTCCACGTGCCCGA
AGGCGAGGCGTACGCCGCGGTCGAGCATCCGAAGGGCGAGTTCGGCATCTATCTGGTGTCGGACGGCGCGAACAAGCCGT
ACCGGCTCAAGATTCGCGCGCCGGGCTATGCCCATCTGTCCGCGCTCGACGAAATGGCGCGGGGGCACATGATCGCCGAC
GCCGTCACGATCATCGGTACGCAGGACATCGTGTTCGGCGAAATCGACCGCTGA

Upstream 100 bases:

>100_bases
GCGCGTCGTGTACCAGCCGGTGACGATCGAGCCGCGCGAAATCACGCCGCGCGTGATCCGCGAGGATCGCTATGGCGGTC
TGAAACATTAAGGGGGCGTC

Downstream 100 bases:

>100_bases
CGGTCGCGCCGCTCGGTCGGCCCGATCGAGCGGCGAGTCACAAGCGGCGCGCATTCGAGTGCGCCGTCGCAACAAGCTGT
CAAAAGTGAGCGCCAGGTCT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
TGPMIRGSGIAWDLRKKQPYEVYDRIDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRENPGPVITDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIAD
AVTIIGTQDIVFGEIDR

Sequences:

>Translated_417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
TGPMIRGSGIAWDLRKKQPYEVYDRIDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRENPGPVITDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIAD
AVTIIGTQDIVFGEIDR
>Mature_416_residues
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSVPYMDRLDYVSMMVNEHGYVLA
IEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYR
DLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLT
GPMIRGSGIAWDLRKKQPYEVYDRIDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRENPGPVITDNHKVAPPS
RVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADA
VTIIGTQDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=60.6280193236715, Blast_Score=516, Evalue=1e-146,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=59.8039215686275, Blast_Score=500, Evalue=1e-141,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.2926829268293, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1789076, Length=419, Percent_Identity=28.4009546539379, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=27.4509803921569, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17555284, Length=414, Percent_Identity=57.9710144927536, Blast_Score=488, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17568379, Length=414, Percent_Identity=56.7632850241546, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=60, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=54.8543689320388, Blast_Score=467, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47451; Mature: 47320

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSV
CCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHEECC
TGPMIRGSGIAWDLRKKQPYEVYDRIDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCI
CCCCEECCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRENPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTFIQSV
CCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHEECC
TGPMIRGSGIAWDLRKKQPYEVYDRIDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCI
CCCCEECCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRENPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCEEECCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA